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Volumn 127, Issue 2, 2010, Pages 148-155

Cardiovascular risk factors regulate the expression of vascular endothelin receptors

Author keywords

Cardiovascular disease; Cardiovascular risk factors; Endothelin; MAPK signaling; Receptor

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; 4 TERT BUTYL N [6 (2 HYDROXYETHOXY) 5 (3 METHOXYPHENOXY) 4 PYRIMIDINYL]BENZENESULFONAMIDE; BOSENTAN; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN RECEPTOR; G PROTEIN COUPLED RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LOW DENSITY LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; SB 386023; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 77954213061     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2010.04.013     Document Type: Review
Times cited : (42)

References (119)
  • 1
    • 0025718651 scopus 로고
    • Cloning and characterization of cDNA encoding human A-type endothelin receptor
    • Adachi M., Yang Y.Y., Furuichi Y., Miyamoto C. Cloning and characterization of cDNA encoding human A-type endothelin receptor. Biochem Biophys Res Commun 1991, 180:1265-1272.
    • (1991) Biochem Biophys Res Commun , vol.180 , pp. 1265-1272
    • Adachi, M.1    Yang, Y.Y.2    Furuichi, Y.3    Miyamoto, C.4
  • 2
    • 0029853692 scopus 로고    scopus 로고
    • Plasticity of contractile endothelin-B receptors in human arteries after organ culture
    • Adner M., Cantera L., Ehlert F., Nilsson L., Edvinsson L. Plasticity of contractile endothelin-B receptors in human arteries after organ culture. Br J Pharmacol 1996, 119:1159-1166.
    • (1996) Br J Pharmacol , vol.119 , pp. 1159-1166
    • Adner, M.1    Cantera, L.2    Ehlert, F.3    Nilsson, L.4    Edvinsson, L.5
  • 3
    • 0031865908 scopus 로고    scopus 로고
    • Appearance of contractile endothelin-B receptors in rat mesenteric arterial segments following organ culture
    • Adner M., Geary G.G., Edvinsson L. Appearance of contractile endothelin-B receptors in rat mesenteric arterial segments following organ culture. Acta Physiol Scand 1998, 163:121-129.
    • (1998) Acta Physiol Scand , vol.163 , pp. 121-129
    • Adner, M.1    Geary, G.G.2    Edvinsson, L.3
  • 4
    • 0031912193 scopus 로고    scopus 로고
    • Regional variation in appearance of vascular contractile endothelin-B receptors following organ culture
    • Adner M., Uddman E., Cardell L.O., Edvinsson L. Regional variation in appearance of vascular contractile endothelin-B receptors following organ culture. Cardiovasc Res 1998, 37:254-262.
    • (1998) Cardiovasc Res , vol.37 , pp. 254-262
    • Adner, M.1    Uddman, E.2    Cardell, L.O.3    Edvinsson, L.4
  • 5
    • 0033607259 scopus 로고    scopus 로고
    • MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia
    • Alessandrini A., Namura S., Moskowitz M.A., Bonventre J.V. MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia. Proc Natl Acad Sci USA 1999, 96:12866-12869.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12866-12869
    • Alessandrini, A.1    Namura, S.2    Moskowitz, M.A.3    Bonventre, J.V.4
  • 6
    • 0029793720 scopus 로고    scopus 로고
    • Effect of immunization with homologous LDL and oxidized LDL on early atherosclerosis in hypercholesterolemic rabbits
    • Ameli S., Hultgardh-Nilsson A., Regnstrom J., Calara F., Yano J., Cercek B., et al. Effect of immunization with homologous LDL and oxidized LDL on early atherosclerosis in hypercholesterolemic rabbits. Arterioscler Thromb Vasc Biol 1996, 16:1074-1079.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1074-1079
    • Ameli, S.1    Hultgardh-Nilsson, A.2    Regnstrom, J.3    Calara, F.4    Yano, J.5    Cercek, B.6
  • 7
    • 38149037346 scopus 로고    scopus 로고
    • Subtype activation and interaction of protein kinase C and mitogen-activated protein kinase controlling receptor expression in cerebral arteries and microvessels after subarachnoid hemorrhage
    • Ansar S., Edvinsson L. Subtype activation and interaction of protein kinase C and mitogen-activated protein kinase controlling receptor expression in cerebral arteries and microvessels after subarachnoid hemorrhage. Stroke 2008, 39:185-190.
    • (2008) Stroke , vol.39 , pp. 185-190
    • Ansar, S.1    Edvinsson, L.2
  • 8
    • 0025605345 scopus 로고
    • Cloning and expression of a cDNA encoding an endothelin receptor
    • Arai H., Hori S., Aramori I., Ohkubo H., Nakanishi S. Cloning and expression of a cDNA encoding an endothelin receptor. Nature 1990, 348:730-732.
    • (1990) Nature , vol.348 , pp. 730-732
    • Arai, H.1    Hori, S.2    Aramori, I.3    Ohkubo, H.4    Nakanishi, S.5
  • 9
    • 0035124607 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia
    • Barone F.C., Irving E.A., Ray A.M., Lee J.C., Kassis S., Kumar S., et al. Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia. Med Res Rev 2001, 21:129-145.
    • (2001) Med Res Rev , vol.21 , pp. 129-145
    • Barone, F.C.1    Irving, E.A.2    Ray, A.M.3    Lee, J.C.4    Kassis, S.5    Kumar, S.6
  • 10
    • 33745698916 scopus 로고    scopus 로고
    • ERK1/2 inhibition attenuates cerebral blood flow reduction and abolishes ET(B) and 5-HT(1B) receptor upregulation after subarachnoid hemorrhage in rat
    • Beg S.A., Hansen-Schwartz J.A., Vikman P.J., Xu C.B., Edvinsson L. ERK1/2 inhibition attenuates cerebral blood flow reduction and abolishes ET(B) and 5-HT(1B) receptor upregulation after subarachnoid hemorrhage in rat. J Cereb Blood Flow Metab 2006, 26:846-856.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 846-856
    • Beg, S.A.1    Hansen-Schwartz, J.A.2    Vikman, P.J.3    Xu, C.B.4    Edvinsson, L.5
  • 11
    • 33845775387 scopus 로고    scopus 로고
    • Protein kinase C inhibition prevents upregulation of vascular ET(B) and 5-HT(1B) receptors and reverses cerebral blood flow reduction after subarachnoid haemorrhage in rats
    • Beg S.S., Hansen-Schwartz J.A., Vikman P.J., Xu C.B., Edvinsson L. Protein kinase C inhibition prevents upregulation of vascular ET(B) and 5-HT(1B) receptors and reverses cerebral blood flow reduction after subarachnoid haemorrhage in rats. J Cereb Blood Flow Metab 2007, 27:21-32.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 21-32
    • Beg, S.S.1    Hansen-Schwartz, J.A.2    Vikman, P.J.3    Xu, C.B.4    Edvinsson, L.5
  • 12
    • 0033144604 scopus 로고    scopus 로고
    • Passive smoking as well as active smoking increases the risk of acute stroke
    • Bonita R., Duncan J., Truelsen T., Jackson R.T., Beaglehole R. Passive smoking as well as active smoking increases the risk of acute stroke. Tob Control 1999, 8:156-160.
    • (1999) Tob Control , vol.8 , pp. 156-160
    • Bonita, R.1    Duncan, J.2    Truelsen, T.3    Jackson, R.T.4    Beaglehole, R.5
  • 13
    • 0037192332 scopus 로고    scopus 로고
    • Improved endothelium-dependent vasodilation after blockade of endothelin receptors in patients with essential hypertension
    • Cardillo C., Campia U., Kilcoyne C.M., Bryant M.B., Panza J.A. Improved endothelium-dependent vasodilation after blockade of endothelin receptors in patients with essential hypertension. Circulation 2002, 105:452-456.
    • (2002) Circulation , vol.105 , pp. 452-456
    • Cardillo, C.1    Campia, U.2    Kilcoyne, C.M.3    Bryant, M.B.4    Panza, J.A.5
  • 14
    • 0034332783 scopus 로고    scopus 로고
    • Increased activity of endogenous endothelin in patients with hypercholesterolemia
    • Cardillo C., Kilcoyne C.M., Cannon R.O., Panza J.A. Increased activity of endogenous endothelin in patients with hypercholesterolemia. J Am Coll Cardiol 2000, 36:1483-1488.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1483-1488
    • Cardillo, C.1    Kilcoyne, C.M.2    Cannon, R.O.3    Panza, J.A.4
  • 15
    • 0032999576 scopus 로고    scopus 로고
    • Role of endothelin in the increased vascular tone of patients with essential hypertension
    • Cardillo C., Kilcoyne C.M., Waclawiw M., Cannon R.O., Panza J.A. Role of endothelin in the increased vascular tone of patients with essential hypertension. Hypertension 1999, 33:753-758.
    • (1999) Hypertension , vol.33 , pp. 753-758
    • Cardillo, C.1    Kilcoyne, C.M.2    Waclawiw, M.3    Cannon, R.O.4    Panza, J.A.5
  • 16
    • 59149104504 scopus 로고    scopus 로고
    • Oxidized LDL affects smooth muscle cell growth through MAPK-mediated actions on nuclear protein import
    • Chahine M.N., Blackwood D.P., Dibrov E., Richard M.N., Pierce G.N. Oxidized LDL affects smooth muscle cell growth through MAPK-mediated actions on nuclear protein import. J Mol Cell cardiol 2009, 46:431-441.
    • (2009) J Mol Cell cardiol , vol.46 , pp. 431-441
    • Chahine, M.N.1    Blackwood, D.P.2    Dibrov, E.3    Richard, M.N.4    Pierce, G.N.5
  • 17
    • 68249144367 scopus 로고    scopus 로고
    • Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells
    • Chen Q.W., Edvinsson L., Xu C.B. Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells. BMC Cell Biol 2009, 10:52.
    • (2009) BMC Cell Biol , vol.10 , pp. 52
    • Chen, Q.W.1    Edvinsson, L.2    Xu, C.B.3
  • 18
    • 3342974363 scopus 로고    scopus 로고
    • The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a >>MEK-ERK and Akt-independent mechanism
    • Chin P.C., Liu L., Morrison B.E., Siddiq A., Ratan R.R., Bottiglieri T., et al. The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a >>MEK-ERK and Akt-independent mechanism. J Neurochem 2004, 90:595-608.
    • (2004) J Neurochem , vol.90 , pp. 595-608
    • Chin, P.C.1    Liu, L.2    Morrison, B.E.3    Siddiq, A.4    Ratan, R.R.5    Bottiglieri, T.6
  • 19
    • 0028113411 scopus 로고
    • Signal transduction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin
    • Chun M., Liyanage U.K., Lisanti M.P., Lodish H.F. Signal transduction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin. Proc Natl Acad Sci USA 1994, 91:11728-11732.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11728-11732
    • Chun, M.1    Liyanage, U.K.2    Lisanti, M.P.3    Lodish, H.F.4
  • 20
    • 0027369239 scopus 로고
    • Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist
    • Clozel M., Breu V., Burri K., Cassal J.M., Fischli W., Gray G.A., et al. Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist. Nature 1993, 365:759-761.
    • (1993) Nature , vol.365 , pp. 759-761
    • Clozel, M.1    Breu, V.2    Burri, K.3    Cassal, J.M.4    Fischli, W.5    Gray, G.A.6
  • 21
    • 0028292620 scopus 로고
    • Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist
    • Clozel M., Breu V., Gray G.A., Kalina B., Loffler B.M., Burri K., et al. Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist. J Pharmacol Exp Ther 1994, 270:228-235.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 228-235
    • Clozel, M.1    Breu, V.2    Gray, G.A.3    Kalina, B.4    Loffler, B.M.5    Burri, K.6
  • 22
    • 0343247780 scopus 로고    scopus 로고
    • Subtype-specific desensitization of human endothelin ETA and ETB receptors reflects differential receptor phosphorylation
    • Cramer H., Muller-Esterl W., Schroeder C. Subtype-specific desensitization of human endothelin ETA and ETB receptors reflects differential receptor phosphorylation. Biochemistry 1997, 36:13325-13332.
    • (1997) Biochemistry , vol.36 , pp. 13325-13332
    • Cramer, H.1    Muller-Esterl, W.2    Schroeder, C.3
  • 23
    • 0034786636 scopus 로고    scopus 로고
    • Coupling of endothelin receptors to the ERK/MAP kinase pathway. Roles of palmitoylation and G(alpha)q
    • Cramer H., Schmenger K., Heinrich K., Horstmeyer A., Boning H., Breit A., et al. Coupling of endothelin receptors to the ERK/MAP kinase pathway. Roles of palmitoylation and G(alpha)q. Eur J Biochem 2001, 268:5449-5459.
    • (2001) Eur J Biochem , vol.268 , pp. 5449-5459
    • Cramer, H.1    Schmenger, K.2    Heinrich, K.3    Horstmeyer, A.4    Boning, H.5    Breit, A.6
  • 24
  • 27
    • 27744603554 scopus 로고    scopus 로고
    • Reducing residual risk for patients on statin therapy: the potential role of combination therapy
    • (discussion 34K-35K)
    • Davidson M.H. Reducing residual risk for patients on statin therapy: the potential role of combination therapy. Am J Cardiol 2005, 96:3K-13K. (discussion 34K-35K).
    • (2005) Am J Cardiol , vol.96
    • Davidson, M.H.1
  • 28
    • 77953204816 scopus 로고    scopus 로고
    • Cardiovascular risk stratification in unselected primary care patients with newly detected arterial hypertension
    • Dieterle T., Sigle J.P., Bengel G., Kiefer G., Brenneisen V., Martina B. Cardiovascular risk stratification in unselected primary care patients with newly detected arterial hypertension. Hypertens Res 2010, 33:607-615.
    • (2010) Hypertens Res , vol.33 , pp. 607-615
    • Dieterle, T.1    Sigle, J.P.2    Bengel, G.3    Kiefer, G.4    Brenneisen, V.5    Martina, B.6
  • 29
    • 77049111525 scopus 로고    scopus 로고
    • Increased tissue endothelin-1 and endothelin-B receptor expression in temporal arteries from patients with giant cell arteritis
    • Dimitrijevic I., Andersson C., Rissler P., Edvinsson L. Increased tissue endothelin-1 and endothelin-B receptor expression in temporal arteries from patients with giant cell arteritis. Ophthalmology 2010, 117:628-636.
    • (2010) Ophthalmology , vol.117 , pp. 628-636
    • Dimitrijevic, I.1    Andersson, C.2    Rissler, P.3    Edvinsson, L.4
  • 30
    • 70349329422 scopus 로고    scopus 로고
    • Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease
    • Dimitrijevic I., Edvinsson M.L., Chen Q., Malmsjo M., Kimblad P.O., Edvinsson L. Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. BMC Cardiovasc Disord 2009, 9:40.
    • (2009) BMC Cardiovasc Disord , vol.9 , pp. 40
    • Dimitrijevic, I.1    Edvinsson, M.L.2    Chen, Q.3    Malmsjo, M.4    Kimblad, P.O.5    Edvinsson, L.6
  • 31
    • 0028827684 scopus 로고
    • Pharmacologic evidence for the presence of three functional endothelin receptor subtypes in rabbit saphenous vein
    • Douglas S.A., Beck G.R., Elliott J.D., Ohlstein E.H. Pharmacologic evidence for the presence of three functional endothelin receptor subtypes in rabbit saphenous vein. J Cardiovasc Pharmacol 1995, 26:S163-S168.
    • (1995) J Cardiovasc Pharmacol , vol.26
    • Douglas, S.A.1    Beck, G.R.2    Elliott, J.D.3    Ohlstein, E.H.4
  • 32
    • 70349567634 scopus 로고    scopus 로고
    • Carotid intima-media thickness, systemic inflammation, and incidence of heart failure hospitalizations
    • Engstrom G., Melander O., Hedblad B. Carotid intima-media thickness, systemic inflammation, and incidence of heart failure hospitalizations. Arterioscler Thromb Vasc Biol 2009, 29:1691-1695.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1691-1695
    • Engstrom, G.1    Melander, O.2    Hedblad, B.3
  • 33
    • 23044450323 scopus 로고    scopus 로고
    • Role of smoking in global and regional cardiovascular mortality
    • Ezzati M., Henley S.J., Thun M.J., Lopez A.D. Role of smoking in global and regional cardiovascular mortality. Circulation 2005, 112:489-497.
    • (2005) Circulation , vol.112 , pp. 489-497
    • Ezzati, M.1    Henley, S.J.2    Thun, M.J.3    Lopez, A.D.4
  • 35
    • 0031702543 scopus 로고    scopus 로고
    • Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes
    • Freigang S., Horkko S., Miller E., Witztum J.L., Palinski W. Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes. Arterioscler Thromb Vasc Biol 1998, 18:1972-1982.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1972-1982
    • Freigang, S.1    Horkko, S.2    Miller, E.3    Witztum, J.L.4    Palinski, W.5
  • 36
    • 0025615664 scopus 로고
    • Plasma renin activity, angiotensin II, prostacyclin and thromboxane A2 concentrations in 139 preeclamptic patients
    • Furuhashi N., Tsujiei M., Kimura H., Yajima A., Kimura C., Ide Y. Plasma renin activity, angiotensin II, prostacyclin and thromboxane A2 concentrations in 139 preeclamptic patients. Tohoku J Exp Med 1990, 162:235-241.
    • (1990) Tohoku J Exp Med , vol.162 , pp. 235-241
    • Furuhashi, N.1    Tsujiei, M.2    Kimura, H.3    Yajima, A.4    Kimura, C.5    Ide, Y.6
  • 37
    • 45249119855 scopus 로고    scopus 로고
    • Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial
    • Galie N., Rubin L., Hoeper M., Jansa P., Al-Hiti H., Meyer G., et al. Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial. Lancet 2008, 371:2093-2100.
    • (2008) Lancet , vol.371 , pp. 2093-2100
    • Galie, N.1    Rubin, L.2    Hoeper, M.3    Jansa, P.4    Al-Hiti, H.5    Meyer, G.6
  • 38
    • 77449130241 scopus 로고    scopus 로고
    • Persistent use of secondary preventive drugs declines rapidly during the first 2years after stroke
    • Glader E.L., Sjolander M., Eriksson M., Lundberg M. Persistent use of secondary preventive drugs declines rapidly during the first 2years after stroke. Stroke 2010, 41:397-401.
    • (2010) Stroke , vol.41 , pp. 397-401
    • Glader, E.L.1    Sjolander, M.2    Eriksson, M.3    Lundberg, M.4
  • 39
    • 0033624157 scopus 로고    scopus 로고
    • Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction
    • Gohla A., Schultz G., Offermanns S. Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction. Circ Res 2000, 87:221-227.
    • (2000) Circ Res , vol.87 , pp. 221-227
    • Gohla, A.1    Schultz, G.2    Offermanns, S.3
  • 40
    • 0033838131 scopus 로고    scopus 로고
    • Localization and function of ET-1 and ET receptors in small arteries post-myocardial infarction: upregulation of smooth muscle ET(B) receptors that modulate contraction
    • Gray G.A., Mickley E.J., Webb D.J., McEwan P.E. Localization and function of ET-1 and ET receptors in small arteries post-myocardial infarction: upregulation of smooth muscle ET(B) receptors that modulate contraction. Br J Pharmacol 2000, 130:1735-1744.
    • (2000) Br J Pharmacol , vol.130 , pp. 1735-1744
    • Gray, G.A.1    Mickley, E.J.2    Webb, D.J.3    McEwan, P.E.4
  • 41
    • 0030775322 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular disease
    • Griendling K.K., Alexander R.W. Oxidative stress and cardiovascular disease. Circulation 1997, 96:3264-3265.
    • (1997) Circulation , vol.96 , pp. 3264-3265
    • Griendling, K.K.1    Alexander, R.W.2
  • 42
    • 0028288965 scopus 로고
    • Elevated endothelin-1 levels after cigarette smoking
    • Haak T., Jungmann E., Raab C., Usadel K.H. Elevated endothelin-1 levels after cigarette smoking. Metabolism 1994, 43:267-269.
    • (1994) Metabolism , vol.43 , pp. 267-269
    • Haak, T.1    Jungmann, E.2    Raab, C.3    Usadel, K.H.4
  • 43
    • 0037406222 scopus 로고    scopus 로고
    • Subarachnoid hemorrhage enhances endothelin receptor expression and function in rat cerebral arteries. Neurosurgery 52, 1188-1194; 1194-1185.
    • Hansen-Schwartz, J., Hoel, N. L., Zhou, M., Xu, C. B., Svendgaard, N. A., & Edvinsson, L. (2003). Subarachnoid hemorrhage enhances endothelin receptor expression and function in rat cerebral arteries. Neurosurgery 52, 1188-1194; 1194-1185.
    • (2003)
    • Hansen-Schwartz, J.1    Hoel, N.L.2    Zhou, M.3    Xu, C.B.4    Svendgaard, N.A.5    Edvinsson, L.6
  • 45
    • 33846614175 scopus 로고    scopus 로고
    • Protein kinase C inhibition attenuates vascular ETB receptor upregulation and decreases brain damage after cerebral ischemia in rat
    • Henriksson M., Stenman E., Vikman P., Edvinsson L. Protein kinase C inhibition attenuates vascular ETB receptor upregulation and decreases brain damage after cerebral ischemia in rat. BMC Neurosci 2007, 8:7.
    • (2007) BMC Neurosci , vol.8 , pp. 7
    • Henriksson, M.1    Stenman, E.2    Vikman, P.3    Edvinsson, L.4
  • 46
    • 4143053531 scopus 로고    scopus 로고
    • Importance of ERK1/2 in upregulation of endothelin type B receptors in cerebral arteries
    • Henriksson M., Xu C.B., Edvinsson L. Importance of ERK1/2 in upregulation of endothelin type B receptors in cerebral arteries. Br J Pharmacol 2004, 142:1155-1161.
    • (2004) Br J Pharmacol , vol.142 , pp. 1155-1161
    • Henriksson, M.1    Xu, C.B.2    Edvinsson, L.3
  • 47
    • 33947139110 scopus 로고    scopus 로고
    • Effect of bosentan on plasma endothelin-1 concentration in patients with pulmonary arterial hypertension
    • Hiramoto Y., Shioyama W., Kuroda T., Masaki M., Sugiyama S., Okamoto K., et al. Effect of bosentan on plasma endothelin-1 concentration in patients with pulmonary arterial hypertension. Circ J 2007, 71:367-369.
    • (2007) Circ J , vol.71 , pp. 367-369
    • Hiramoto, Y.1    Shioyama, W.2    Kuroda, T.3    Masaki, M.4    Sugiyama, S.5    Okamoto, K.6
  • 48
    • 0032515362 scopus 로고    scopus 로고
    • Cigarette smoking and progression of atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) Study
    • Howard G., Wagenknecht L.E., Burke G.L., Diez-Roux A., Evans G.W., McGovern P., et al. Cigarette smoking and progression of atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) Study. Jama 1998, 279:119-124.
    • (1998) Jama , vol.279 , pp. 119-124
    • Howard, G.1    Wagenknecht, L.E.2    Burke, G.L.3    Diez-Roux, A.4    Evans, G.W.5    McGovern, P.6
  • 49
    • 39049149953 scopus 로고    scopus 로고
    • The vascular endothelin system in hypertension - recent patents and discoveries
    • Hynynen M.M., Khalil R.A. The vascular endothelin system in hypertension - recent patents and discoveries. Recent Pat Cardiovasc Drug Discov 2006, 1:95-108.
    • (2006) Recent Pat Cardiovasc Drug Discov , vol.1 , pp. 95-108
    • Hynynen, M.M.1    Khalil, R.A.2
  • 50
    • 0026593030 scopus 로고
    • Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor
    • Ihara M., Noguchi K., Saeki T., Fukuroda T., Tsuchida S., Kimura S., et al. Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor. Life Sci 1992, 50:247-255.
    • (1992) Life Sci , vol.50 , pp. 247-255
    • Ihara, M.1    Noguchi, K.2    Saeki, T.3    Fukuroda, T.4    Tsuchida, S.5    Kimura, S.6
  • 51
    • 0013543367 scopus 로고
    • The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes
    • Inoue A., Yanagisawa M., Kimura S., Kasuya Y., Miyauchi T., Goto K., et al. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci USA 1989, 86:2863-2867.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2863-2867
    • Inoue, A.1    Yanagisawa, M.2    Kimura, S.3    Kasuya, Y.4    Miyauchi, T.5    Goto, K.6
  • 52
    • 64549142419 scopus 로고    scopus 로고
    • Systematic review: association of low-density lipoprotein subfractions with cardiovascular outcomes
    • Ip S., Lichtenstein A.H., Chung M., Lau J., Balk E.M. Systematic review: association of low-density lipoprotein subfractions with cardiovascular outcomes. Ann Intern Med 2009, 150:474-484.
    • (2009) Ann Intern Med , vol.150 , pp. 474-484
    • Ip, S.1    Lichtenstein, A.H.2    Chung, M.3    Lau, J.4    Balk, E.M.5
  • 55
    • 0029886630 scopus 로고    scopus 로고
    • Blood pressure as a cardiovascular risk factor: prevention and treatment
    • Kannel W.B. Blood pressure as a cardiovascular risk factor: prevention and treatment. Jama 1996, 275:1571-1576.
    • (1996) Jama , vol.275 , pp. 1571-1576
    • Kannel, W.B.1
  • 56
    • 0027301252 scopus 로고
    • Cloning and characterization of an endothelin-3 specific receptor (ETC receptor) from Xenopus laevis dermal melanophores
    • Karne S., Jayawickreme C.K., Lerner M.R. Cloning and characterization of an endothelin-3 specific receptor (ETC receptor) from Xenopus laevis dermal melanophores. J Biol Chem 1993, 268:19126-19133.
    • (1993) J Biol Chem , vol.268 , pp. 19126-19133
    • Karne, S.1    Jayawickreme, C.K.2    Lerner, M.R.3
  • 57
    • 18444367405 scopus 로고    scopus 로고
    • Acute and chronic effects of cigarette smoking on arterial stiffness
    • Kim J.W., Park C.G., Hong S.J., Park S.M., Rha S.W., Seo H.S., et al. Acute and chronic effects of cigarette smoking on arterial stiffness. Blood press 2005, 14:80-85.
    • (2005) Blood press , vol.14 , pp. 80-85
    • Kim, J.W.1    Park, C.G.2    Hong, S.J.3    Park, S.M.4    Rha, S.W.5    Seo, H.S.6
  • 58
    • 77649246336 scopus 로고    scopus 로고
    • The efficacy of statin therapy in patients with acute coronary syndromes and concomitant carotid disease
    • Komorovsky R., Desideri A., Coscarelli S., Tonello D., Visona A., Celegon L. The efficacy of statin therapy in patients with acute coronary syndromes and concomitant carotid disease. Clin Cardiol 2010, 33:E15-E19.
    • (2010) Clin Cardiol , vol.33
    • Komorovsky, R.1    Desideri, A.2    Coscarelli, S.3    Tonello, D.4    Visona, A.5    Celegon, L.6
  • 60
    • 0031888499 scopus 로고    scopus 로고
    • Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension
    • Lacy F., O'Connor D.T., Schmid-Schonbein G.W. Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension. J Hypertens 1998, 16:291-303.
    • (1998) J Hypertens , vol.16 , pp. 291-303
    • Lacy, F.1    O'Connor, D.T.2    Schmid-Schonbein, G.W.3
  • 61
    • 60549111686 scopus 로고    scopus 로고
    • The Raf-1 inhibitor GW5074 and dexamethasone suppress sidestream smoke-induced airway hyperresponsiveness in mice
    • Lei Y., Cao Y.X., Xu C.B., Zhang Y. The Raf-1 inhibitor GW5074 and dexamethasone suppress sidestream smoke-induced airway hyperresponsiveness in mice. Respir Res 2008, 9:71.
    • (2008) Respir Res , vol.9 , pp. 71
    • Lei, Y.1    Cao, Y.X.2    Xu, C.B.3    Zhang, Y.4
  • 62
    • 36549034768 scopus 로고    scopus 로고
    • Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths
    • Lewington S., Whitlock G., Clarke R., Sherliker P., Emberson J., Halsey J., et al. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet 2007, 370:1829-1839.
    • (2007) Lancet , vol.370 , pp. 1829-1839
    • Lewington, S.1    Whitlock, G.2    Clarke, R.3    Sherliker, P.4    Emberson, J.5    Halsey, J.6
  • 63
    • 0031900740 scopus 로고    scopus 로고
    • Signal transduction through MAP kinase cascades
    • Lewis T.S., Shapiro P.S., Ahn N.G. Signal transduction through MAP kinase cascades. Adv Cancer Res 1998, 74:49-139.
    • (1998) Adv Cancer Res , vol.74 , pp. 49-139
    • Lewis, T.S.1    Shapiro, P.S.2    Ahn, N.G.3
  • 64
    • 33846821685 scopus 로고    scopus 로고
    • Enhanced G-protein coupled receptors-mediated contraction and reduced endothelium-dependent relaxation in hypertension
    • Li J., Cao Y.X., Liu H., Xu C.B. Enhanced G-protein coupled receptors-mediated contraction and reduced endothelium-dependent relaxation in hypertension. Eur J Pharmacol 2007, 557:186-194.
    • (2007) Eur J Pharmacol , vol.557 , pp. 186-194
    • Li, J.1    Cao, Y.X.2    Liu, H.3    Xu, C.B.4
  • 65
    • 1642545106 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis: role of C-reactive protein in risk assessment
    • Libby P., Ridker P.M. Inflammation and atherosclerosis: role of C-reactive protein in risk assessment. Am J Med 2004, 116:9S-16S.
    • (2004) Am J Med , vol.116
    • Libby, P.1    Ridker, P.M.2
  • 66
    • 0033029044 scopus 로고    scopus 로고
    • Selective increase of the contractile response to endothelin-1 in subcutaneous arteries from patients with essential hypertension
    • Lind H., Adner M., Erlinge D., Brunkwall J., Edvinsson L. Selective increase of the contractile response to endothelin-1 in subcutaneous arteries from patients with essential hypertension. Blood Press 1999, 8:9-15.
    • (1999) Blood Press , vol.8 , pp. 9-15
    • Lind, H.1    Adner, M.2    Erlinge, D.3    Brunkwall, J.4    Edvinsson, L.5
  • 67
    • 49249118773 scopus 로고    scopus 로고
    • Role of thromboxane A(2) receptor on the effects of oxidized LDL on microvascular endothelium nitric oxide, endothelin-1, and IL-6 production
    • Lubrano V., Baldi S., Ferrannini E., L'Abbate A., Natali A. Role of thromboxane A(2) receptor on the effects of oxidized LDL on microvascular endothelium nitric oxide, endothelin-1, and IL-6 production. Microcirculation 2008, 15:543-553.
    • (2008) Microcirculation , vol.15 , pp. 543-553
    • Lubrano, V.1    Baldi, S.2    Ferrannini, E.3    L'Abbate, A.4    Natali, A.5
  • 69
    • 33744727235 scopus 로고    scopus 로고
    • Endothelin-1: the yin and yang on vascular function
    • Marasciulo F.L., Montagnani M., Potenza M.A. Endothelin-1: the yin and yang on vascular function. Curr Med Chem 2006, 13:1655-1665.
    • (2006) Curr Med Chem , vol.13 , pp. 1655-1665
    • Marasciulo, F.L.1    Montagnani, M.2    Potenza, M.A.3
  • 72
    • 0036634351 scopus 로고    scopus 로고
    • Darusentan: an effective endothelinA receptor antagonist for treatment of hypertension
    • Nakov R., Pfarr E., Eberle S. Darusentan: an effective endothelinA receptor antagonist for treatment of hypertension. Am J Hypertens 2002, 15:583-589.
    • (2002) Am J Hypertens , vol.15 , pp. 583-589
    • Nakov, R.1    Pfarr, E.2    Eberle, S.3
  • 73
    • 0035949472 scopus 로고    scopus 로고
    • Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia
    • Namura S., Iihara K., Takami S., Nagata I., Kikuchi H., Matsushita K., et al. Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia. Proc Natl Acad Sci USA 2001, 98:11569-11574.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 11569-11574
    • Namura, S.1    Iihara, K.2    Takami, S.3    Nagata, I.4    Kikuchi, H.5    Matsushita, K.6
  • 74
    • 39449106613 scopus 로고    scopus 로고
    • Increased ET(A) and ET(B) receptor contraction in the left internal mammary artery from patients with hypertension
    • Nilsson D., Wackenfors A., Gustafsson L., Edvinsson L., Paulsson P., Ingemansson R., et al. Increased ET(A) and ET(B) receptor contraction in the left internal mammary artery from patients with hypertension. J Hum Hypertens 2008, 22:226-229.
    • (2008) J Hum Hypertens , vol.22 , pp. 226-229
    • Nilsson, D.1    Wackenfors, A.2    Gustafsson, L.3    Edvinsson, L.4    Paulsson, P.5    Ingemansson, R.6
  • 77
    • 0027459416 scopus 로고
    • Antihypertensive effect of a newly synthesized endothelin antagonist, BQ-123, in a genetic hypertensive model
    • Nishikibe M., Tsuchida S., Okada M., Fukuroda T., Shimamoto K., Yano M., et al. Antihypertensive effect of a newly synthesized endothelin antagonist, BQ-123, in a genetic hypertensive model. Life Sci 1993, 52:717-724.
    • (1993) Life Sci , vol.52 , pp. 717-724
    • Nishikibe, M.1    Tsuchida, S.2    Okada, M.3    Fukuroda, T.4    Shimamoto, K.5    Yano, M.6
  • 78
    • 0028895573 scopus 로고
    • Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis
    • Palinski W., Miller E., Witztum J.L. Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis. Proc Natl Acad Sci USA 1995, 92:821-825.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 821-825
    • Palinski, W.1    Miller, E.2    Witztum, J.L.3
  • 79
    • 0033743318 scopus 로고    scopus 로고
    • Enhanced vasoconstrictor response to endothelin-B-receptor stimulation in patients with atherosclerosis
    • Pernow J., Bohm F., Johansson B.L., Hedin U., Ryden L. Enhanced vasoconstrictor response to endothelin-B-receptor stimulation in patients with atherosclerosis. J Cardiovasc Pharmacol 2000, 36:S418-S420.
    • (2000) J Cardiovasc Pharmacol , vol.36
    • Pernow, J.1    Bohm, F.2    Johansson, B.L.3    Hedin, U.4    Ryden, L.5
  • 80
    • 0242410275 scopus 로고    scopus 로고
    • Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study
    • Raitakari O.T., Juonala M., Kahonen M., Taittonen L., Laitinen T., Maki-Torkko N., et al. Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study. Jama 2003, 290:2277-2283.
    • (2003) Jama , vol.290 , pp. 2277-2283
    • Raitakari, O.T.1    Juonala, M.2    Kahonen, M.3    Taittonen, L.4    Laitinen, T.5    Maki-Torkko, N.6
  • 81
    • 33846451061 scopus 로고    scopus 로고
    • Expression and immunolocalization of endothelin peptides and its receptors, ETA and ETB, in the carotid body exposed to chronic intermittent hypoxia
    • Rey S., Corthorn J., Chacon C., Iturriaga R. Expression and immunolocalization of endothelin peptides and its receptors, ETA and ETB, in the carotid body exposed to chronic intermittent hypoxia. J Histochem Cytochem 2007, 55:167-174.
    • (2007) J Histochem Cytochem , vol.55 , pp. 167-174
    • Rey, S.1    Corthorn, J.2    Chacon, C.3    Iturriaga, R.4
  • 82
    • 34248669012 scopus 로고    scopus 로고
    • Acute effects of cigarette smoking on arterial stiffness and blood pressure in male smokers with hypertension
    • Rhee M.Y., Na S.H., Kim Y.K., Lee M.M., Kim H.Y. Acute effects of cigarette smoking on arterial stiffness and blood pressure in male smokers with hypertension. Am J Hypertens 2007, 20:637-641.
    • (2007) Am J Hypertens , vol.20 , pp. 637-641
    • Rhee, M.Y.1    Na, S.H.2    Kim, Y.K.3    Lee, M.M.4    Kim, H.Y.5
  • 83
    • 0031045954 scopus 로고    scopus 로고
    • Enhanced expression of endothelin-1 gene in resistance arteries in severe human essential hypertension
    • Schiffrin E.L., Deng L.Y., Sventek P., Day R. Enhanced expression of endothelin-1 gene in resistance arteries in severe human essential hypertension. J Hypertens 1997, 15:57-63.
    • (1997) J Hypertens , vol.15 , pp. 57-63
    • Schiffrin, E.L.1    Deng, L.Y.2    Sventek, P.3    Day, R.4
  • 84
    • 0027960431 scopus 로고
    • Molecular characterization of human and bovine endothelin converting enzyme (ECE-1)
    • Schmidt M., Kroger B., Jacob E., Seulberger H., Subkowski T., Otter R., et al. Molecular characterization of human and bovine endothelin converting enzyme (ECE-1). FEBS Lett 1994, 356:238-243.
    • (1994) FEBS Lett , vol.356 , pp. 238-243
    • Schmidt, M.1    Kroger, B.2    Jacob, E.3    Seulberger, H.4    Subkowski, T.5    Otter, R.6
  • 85
    • 33847031260 scopus 로고    scopus 로고
    • Contrasting actions of endothelin ET(A) and ET(B) receptors in cardiovascular disease
    • Schneider M.P., Boesen E.I., Pollock D.M. Contrasting actions of endothelin ET(A) and ET(B) receptors in cardiovascular disease. Annu Rev Pharmacol Toxicol 2007, 47:731-759.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 731-759
    • Schneider, M.P.1    Boesen, E.I.2    Pollock, D.M.3
  • 86
    • 0028261084 scopus 로고
    • Cloning and functional expression of endothelin-converting enzyme from rat endothelial cells
    • Shimada K., Takahashi M., Tanzawa K. Cloning and functional expression of endothelin-converting enzyme from rat endothelial cells. J Biol Chem 1994, 269:18275-18278.
    • (1994) J Biol Chem , vol.269 , pp. 18275-18278
    • Shimada, K.1    Takahashi, M.2    Tanzawa, K.3
  • 87
    • 0034090823 scopus 로고    scopus 로고
    • Functional coupling of G proteins to endothelin receptors is ligand and receptor subtype specific
    • Shraga-Levine Z., Sokolovsky M. Functional coupling of G proteins to endothelin receptors is ligand and receptor subtype specific. Cell Mol Neurobiol 2000, 20:305-317.
    • (2000) Cell Mol Neurobiol , vol.20 , pp. 305-317
    • Shraga-Levine, Z.1    Sokolovsky, M.2
  • 88
    • 0020673707 scopus 로고
    • Systemic excretion of benzo(a)pyrene in the control and microsomally induced rat: the influence of plasma lipoproteins and albumin as carrier molecules
    • Shu H.P., Bymun E.N. Systemic excretion of benzo(a)pyrene in the control and microsomally induced rat: the influence of plasma lipoproteins and albumin as carrier molecules. Cancer Res 1983, 43:485-490.
    • (1983) Cancer Res , vol.43 , pp. 485-490
    • Shu, H.P.1    Bymun, E.N.2
  • 89
    • 0029837395 scopus 로고    scopus 로고
    • Rediscovering an endothelin antagonist (BQ-123): a self-deconvoluting cyclic pentapeptide library
    • Spatola A.F., Crozet Y. Rediscovering an endothelin antagonist (BQ-123): a self-deconvoluting cyclic pentapeptide library. J Medicinal Chem 1996, 39:3842-3846.
    • (1996) J Medicinal Chem , vol.39 , pp. 3842-3846
    • Spatola, A.F.1    Crozet, Y.2
  • 90
    • 0028203238 scopus 로고
    • The discovery of sulfonamide endothelin antagonists and the development of the orally active ETA antagonist 5-(dimethylamino)-N-(3, 4-dimethyl-5-isoxazolyl)-1-naphthalenesulf onamide
    • Stein P.D., Hunt J.T., Floyd D.M., Moreland S., Dickinson K.E., Mitchell C., et al. The discovery of sulfonamide endothelin antagonists and the development of the orally active ETA antagonist 5-(dimethylamino)-N-(3, 4-dimethyl-5-isoxazolyl)-1-naphthalenesulf onamide. J Med Chem 1994, 37:329-331.
    • (1994) J Med Chem , vol.37 , pp. 329-331
    • Stein, P.D.1    Hunt, J.T.2    Floyd, D.M.3    Moreland, S.4    Dickinson, K.E.5    Mitchell, C.6
  • 91
    • 34547903660 scopus 로고    scopus 로고
    • Cooperative effect of angiotensin AT(1) and endothelin ET(A) receptor antagonism limits the brain damage after ischemic stroke in rat
    • Stenman E., Jamali R., Henriksson M., Maddahi A., Edvinsson L. Cooperative effect of angiotensin AT(1) and endothelin ET(A) receptor antagonism limits the brain damage after ischemic stroke in rat. Eur J Pharmacol 2007, 570:142-148.
    • (2007) Eur J Pharmacol , vol.570 , pp. 142-148
    • Stenman, E.1    Jamali, R.2    Henriksson, M.3    Maddahi, A.4    Edvinsson, L.5
  • 92
    • 0036713458 scopus 로고    scopus 로고
    • Cerebral ischemia upregulates vascular endothelin ET(B) receptors in rat
    • Stenman E., Malmsjo M., Uddman E., Gido G., Wieloch T., Edvinsson L. Cerebral ischemia upregulates vascular endothelin ET(B) receptors in rat. Stroke 2002, 33:2311-2316.
    • (2002) Stroke , vol.33 , pp. 2311-2316
    • Stenman, E.1    Malmsjo, M.2    Uddman, E.3    Gido, G.4    Wieloch, T.5    Edvinsson, L.6
  • 94
    • 0026911134 scopus 로고
    • Inhibition of endothelin (ET-1) induced pressor responses by the endothelin (ETA) receptor antagonist FR139317 in the pithed rat
    • Sun X.Y., Hedner T., Feng Q., Edvinsson L. Inhibition of endothelin (ET-1) induced pressor responses by the endothelin (ETA) receptor antagonist FR139317 in the pithed rat. Blood Press 1992, 1:108-112.
    • (1992) Blood Press , vol.1 , pp. 108-112
    • Sun, X.Y.1    Hedner, T.2    Feng, Q.3    Edvinsson, L.4
  • 95
    • 0033584711 scopus 로고    scopus 로고
    • Vasoconstriction to endogenous endothelin-1 is increased in the peripheral circulation of patients with essential hypertension
    • Taddei S., Virdis A., Ghiadoni L., Sudano I., Notari M., Salvetti A. Vasoconstriction to endogenous endothelin-1 is increased in the peripheral circulation of patients with essential hypertension. Circulation 1999, 100:1680-1683.
    • (1999) Circulation , vol.100 , pp. 1680-1683
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Sudano, I.4    Notari, M.5    Salvetti, A.6
  • 96
    • 33745947105 scopus 로고    scopus 로고
    • C-reactive protein as a predictor of incident ischemic stroke among patients with preexisting cardiovascular disease
    • Tanne D., Benderly M., Goldbourt U., Haim M., Tenenbaum A., Fisman E.Z., et al. C-reactive protein as a predictor of incident ischemic stroke among patients with preexisting cardiovascular disease. Stroke 2006, 37:1720-1724.
    • (2006) Stroke , vol.37 , pp. 1720-1724
    • Tanne, D.1    Benderly, M.2    Goldbourt, U.3    Haim, M.4    Tenenbaum, A.5    Fisman, E.Z.6
  • 97
    • 0141754013 scopus 로고    scopus 로고
    • Cloning of bovine preproendothelin-2 cDNA and organ distribution of transcripts
    • Uchide T., Fujimori Y., Temma K., Sasaki T., Saida K. Cloning of bovine preproendothelin-2 cDNA and organ distribution of transcripts. DNA Seq 2003, 14:385-392.
    • (2003) DNA Seq , vol.14 , pp. 385-392
    • Uchide, T.1    Fujimori, Y.2    Temma, K.3    Sasaki, T.4    Saida, K.5
  • 98
    • 0037020476 scopus 로고    scopus 로고
    • Protein kinase C inhibitors decrease endothelin ET(B) receptor mRNA expression and contraction during organ culture of rat mesenteric artery
    • Uddman E., Adner M., Edvinsson L. Protein kinase C inhibitors decrease endothelin ET(B) receptor mRNA expression and contraction during organ culture of rat mesenteric artery. Eur J Pharmacol 2002, 452:215-222.
    • (2002) Eur J Pharmacol , vol.452 , pp. 215-222
    • Uddman, E.1    Adner, M.2    Edvinsson, L.3
  • 99
    • 0344737712 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinases in endothelin ETB receptor up-regulation after organ culture of rat mesenteric artery
    • Uddman E., Henriksson M., Eskesen K., Edvinsson L. Role of mitogen-activated protein kinases in endothelin ETB receptor up-regulation after organ culture of rat mesenteric artery. Eur J Pharmacol 2003, 482:39-47.
    • (2003) Eur J Pharmacol , vol.482 , pp. 39-47
    • Uddman, E.1    Henriksson, M.2    Eskesen, K.3    Edvinsson, L.4
  • 100
    • 0344298886 scopus 로고    scopus 로고
    • Cytokines induce increased endothelin ET(B) receptor-mediated contraction
    • Uddman E., Moller S., Adner M., Edvinsson L. Cytokines induce increased endothelin ET(B) receptor-mediated contraction. Eur J Pharmacol 1999, 376:223-232.
    • (1999) Eur J Pharmacol , vol.376 , pp. 223-232
    • Uddman, E.1    Moller, S.2    Adner, M.3    Edvinsson, L.4
  • 101
    • 0347948449 scopus 로고    scopus 로고
    • Ischemic heart disease induces upregulation of endothelin receptor mRNA in human coronary arteries
    • Wackenfors A., Emilson M., Ingemansson R., Hortobagyi T., Szok D., Tajti J., et al. Ischemic heart disease induces upregulation of endothelin receptor mRNA in human coronary arteries. Eur J Pharmacol 2004, 484:103-109.
    • (2004) Eur J Pharmacol , vol.484 , pp. 103-109
    • Wackenfors, A.1    Emilson, M.2    Ingemansson, R.3    Hortobagyi, T.4    Szok, D.5    Tajti, J.6
  • 102
    • 0037335160 scopus 로고    scopus 로고
    • Endothelin receptors in endothelium-denuded human coronary artery bypass grafts and coronary arteries
    • Wackenfors A., Ingemansson R., Malmsjo M. Endothelin receptors in endothelium-denuded human coronary artery bypass grafts and coronary arteries. Ann Thorac Surg 2003, 75:874-881.
    • (2003) Ann Thorac Surg , vol.75 , pp. 874-881
    • Wackenfors, A.1    Ingemansson, R.2    Malmsjo, M.3
  • 103
    • 0032568476 scopus 로고    scopus 로고
    • Passive smoking induces atherogenic changes in low-density lipoprotein
    • Valkonen M., Kuusi T. Passive smoking induces atherogenic changes in low-density lipoprotein. Circulation 1998, 97:2012-2016.
    • (1998) Circulation , vol.97 , pp. 2012-2016
    • Valkonen, M.1    Kuusi, T.2
  • 104
    • 0030053873 scopus 로고    scopus 로고
    • Expression of endothelin-1, endothelin-3, endothelin-converting enzyme-1, and endothelin-A and endothelin-B receptor mRNA after angioplasty-induced neointimal formation in the rat
    • Wang X., Douglas S.A., Louden C., Vickery-Clark L.M., Feuerstein G.Z., Ohlstein E.H. Expression of endothelin-1, endothelin-3, endothelin-converting enzyme-1, and endothelin-A and endothelin-B receptor mRNA after angioplasty-induced neointimal formation in the rat. Circ Res 1996, 78:322-328.
    • (1996) Circ Res , vol.78 , pp. 322-328
    • Wang, X.1    Douglas, S.A.2    Louden, C.3    Vickery-Clark, L.M.4    Feuerstein, G.Z.5    Ohlstein, E.H.6
  • 105
    • 33644957463 scopus 로고    scopus 로고
    • Hypoxia-induced reactive oxygen species downregulate ETB receptor-mediated contraction of rat pulmonary arteries
    • Wang X., Tong M., Chinta S., Raj J.U., Gao Y. Hypoxia-induced reactive oxygen species downregulate ETB receptor-mediated contraction of rat pulmonary arteries. Am J Physiol Lung Cell Mol Physiol 2006, 290:L570-L578.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290
    • Wang, X.1    Tong, M.2    Chinta, S.3    Raj, J.U.4    Gao, Y.5
  • 106
    • 0029126131 scopus 로고
    • Endothelium-dependent responses in hypertension
    • Vanhoutte P.M., Boulanger C.M. Endothelium-dependent responses in hypertension. Hypertens Res 1995, 18:87-98.
    • (1995) Hypertens Res , vol.18 , pp. 87-98
    • Vanhoutte, P.M.1    Boulanger, C.M.2
  • 107
    • 0027739274 scopus 로고
    • Comparative studies with the endothelin receptor antagonists BQ-123 and PD 142893 indicate at least three endothelin receptors
    • Warner T.D., Allcock G.H., Mickley E.J., Corder R., Vane J.R. Comparative studies with the endothelin receptor antagonists BQ-123 and PD 142893 indicate at least three endothelin receptors. J Cardiovasc Pharmacol 1993, 22:S117-S120.
    • (1993) J Cardiovasc Pharmacol , vol.22
    • Warner, T.D.1    Allcock, G.H.2    Mickley, E.J.3    Corder, R.4    Vane, J.R.5
  • 108
    • 70350133404 scopus 로고    scopus 로고
    • A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial
    • Weber M.A., Black H., Bakris G., Krum H., Linas S., Weiss R., et al. A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial. Lancet 2009, 374:1423-1431.
    • (2009) Lancet , vol.374 , pp. 1423-1431
    • Weber, M.A.1    Black, H.2    Bakris, G.3    Krum, H.4    Linas, S.5    Weiss, R.6
  • 110
    • 0028085436 scopus 로고
    • Interactions between cultured bovine arterial endothelial and smooth muscle cells; effects of modulated low density lipoproteins on cell proliferation and prostacyclin release
    • Xu C.B., Stavenow L., Pessah-Rasmussen H. Interactions between cultured bovine arterial endothelial and smooth muscle cells; effects of modulated low density lipoproteins on cell proliferation and prostacyclin release. Scand J Clin Lab Invest 1994, 54:191-198.
    • (1994) Scand J Clin Lab Invest , vol.54 , pp. 191-198
    • Xu, C.B.1    Stavenow, L.2    Pessah-Rasmussen, H.3
  • 111
    • 56649109924 scopus 로고    scopus 로고
    • Lipid-soluble smoke particles upregulate vascular smooth muscle ETB receptors via activation of mitogen-activating protein kinases and NF-kappaB pathways
    • Xu C.B., Zheng J.P., Zhang W., Zhang Y., Edvinsson L. Lipid-soluble smoke particles upregulate vascular smooth muscle ETB receptors via activation of mitogen-activating protein kinases and NF-kappaB pathways. Toxicol Sci 2008, 106:546-555.
    • (2008) Toxicol Sci , vol.106 , pp. 546-555
    • Xu, C.B.1    Zheng, J.P.2    Zhang, W.3    Zhang, Y.4    Edvinsson, L.5
  • 112
    • 84878749431 scopus 로고    scopus 로고
    • The cardiovascular risk factor DMSO-soluble smoke particles enhance transcription and translation of endothelin type A receptors via activation of PKC? and ERK1/2 pathways in vascular smooth muscle cells
    • (abstr)
    • Xu C.B., Zhang Y., Zhang W., Edvinsson L. The cardiovascular risk factor DMSO-soluble smoke particles enhance transcription and translation of endothelin type A receptors via activation of PKC? and ERK1/2 pathways in vascular smooth muscle cells. Hypertension 2008, 52(770). (abstr).
    • (2008) Hypertension , vol.52 , Issue.770
    • Xu, C.B.1    Zhang, Y.2    Zhang, W.3    Edvinsson, L.4
  • 113
    • 0023859136 scopus 로고
    • A novel potent vasoconstrictor peptide produced by vascular endothelial cells
    • Yanagisawa M., Kurihara H., Kimura S., Tomobe Y., Kobayashi M., Mitsui Y., et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988, 332:411-415.
    • (1988) Nature , vol.332 , pp. 411-415
    • Yanagisawa, M.1    Kurihara, H.2    Kimura, S.3    Tomobe, Y.4    Kobayashi, M.5    Mitsui, Y.6
  • 114
    • 0035067083 scopus 로고    scopus 로고
    • Mitogenic effect of oxidized low-density lipoprotein on vascular smooth muscle cells mediated by activation of Ras/Raf/MEK/MAPK pathway
    • Yang C.M., Chien C.S., Hsiao L.D., Pan S.L., Wang C.C., Chiu C.T., et al. Mitogenic effect of oxidized low-density lipoprotein on vascular smooth muscle cells mediated by activation of Ras/Raf/MEK/MAPK pathway. Br J Pharmacol 2001, 132:1531-1541.
    • (2001) Br J Pharmacol , vol.132 , pp. 1531-1541
    • Yang, C.M.1    Chien, C.S.2    Hsiao, L.D.3    Pan, S.L.4    Wang, C.C.5    Chiu, C.T.6
  • 115
    • 27744541495 scopus 로고    scopus 로고
    • Cloning of cDNA encoding canine endothelin receptors and their expressions in normal tissues
    • Yasuda N., Tsukui T., Masuda K., Kawarai S., Ohmori K., Maeda S., et al. Cloning of cDNA encoding canine endothelin receptors and their expressions in normal tissues. J Vet Med Sci 2005, 67:1075-1079.
    • (2005) J Vet Med Sci , vol.67 , pp. 1075-1079
    • Yasuda, N.1    Tsukui, T.2    Masuda, K.3    Kawarai, S.4    Ohmori, K.5    Maeda, S.6
  • 116
    • 33644763047 scopus 로고    scopus 로고
    • Lipid-soluble smoke particles damage endothelial cells and reduce endothelium-dependent dilatation in rat and man
    • Zhang J.Y., Cao Y.X., Xu C.B., Edvinsson L. Lipid-soluble smoke particles damage endothelial cells and reduce endothelium-dependent dilatation in rat and man. BMC Cardiovasc Disord 2006, 6:3.
    • (2006) BMC Cardiovasc Disord , vol.6 , pp. 3
    • Zhang, J.Y.1    Cao, Y.X.2    Xu, C.B.3    Edvinsson, L.4
  • 117
    • 38349086656 scopus 로고    scopus 로고
    • Up-regulation of thromboxane A2 receptor expression by lipid soluble smoking particles through post-transcriptional mechanisms
    • Zhang W., Zhang Y., Edvinsson L., Xu C.B. Up-regulation of thromboxane A2 receptor expression by lipid soluble smoking particles through post-transcriptional mechanisms. Atherosclerosis 2008, 196:608-616.
    • (2008) Atherosclerosis , vol.196 , pp. 608-616
    • Zhang, W.1    Zhang, Y.2    Edvinsson, L.3    Xu, C.B.4
  • 118
    • 84863239538 scopus 로고    scopus 로고
    • Attenuation of endothelium-dependent relaxation in rat mesenteric arteries by ApoB protein of low density lipoprotein, but not cholesterol
    • (abstr)
    • Zhang Y., Zhang W., Edvinsson L., Xu C.B. Attenuation of endothelium-dependent relaxation in rat mesenteric arteries by ApoB protein of low density lipoprotein, but not cholesterol. Hypertension 2008, 52(768). (abstr).
    • (2008) Hypertension , vol.52 , Issue.768
    • Zhang, Y.1    Zhang, W.2    Edvinsson, L.3    Xu, C.B.4
  • 119
    • 77953290712 scopus 로고    scopus 로고
    • NF-kappaB signalling mediates vascular smooth muscle endothelin type B receptor expression in resistance arteries
    • Zheng J.P., Zhang Y., Edvinsson L., Hjalt T., Xu C.B. NF-kappaB signalling mediates vascular smooth muscle endothelin type B receptor expression in resistance arteries. Eur J Pharmacol 2010, 637:148-154.
    • (2010) Eur J Pharmacol , vol.637 , pp. 148-154
    • Zheng, J.P.1    Zhang, Y.2    Edvinsson, L.3    Hjalt, T.4    Xu, C.B.5


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