Control, management, and prevention of bovine respiratory disease in dairy calves and cows

Veterinary Clinics of North America - Food Animal Practice

Volumn 26, Issue 2, 2010, Pages 243-259

  Gorden, Patrick J ^a   Plummer, Paul ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

Bovine respiratory disease; Control; Dairy calves; Dairy cows; Management

Indexed keywords

ANIMALIA; BOS; BOVINAE;

ANIMAL; ANIMAL DISEASE; CATTLE; CATTLE DISEASE; DAIRYING; FEMALE; MALE; MORTALITY; NEWBORN; REVIEW; STANDARD; VACCINATION; WEANING;

ANIMALS; ANIMALS, NEWBORN; BOVINE RESPIRATORY DISEASE COMPLEX; CATTLE; DAIRYING; FEMALE; MALE; VACCINATION; WEANING;

EID: 77954169685     PISSN: 07490720     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cvfa.2010.03.004     Document Type: Review

References (85)

1. USDA. Dairy 2007, Part V: changes in dairy cattle health and management practices in the United States, 1996-2007. Fort Collins (CO): USDA: APHIS:VS, CEAH; 2009 # 519.0709.
2. Sivula N.J., Ames T.R., Marsh W.E., et al. Descriptive epidemiology of morbidity and mortality in Minnesota dairy heifer calves. Prev Vet Med 1996, 27:155-171.
3. Kaneene J.B., Hurd S. The national animal health monitoring system in Michigan. III. Cost estimates of selected dairy cattle diseases. Prev Vet Med 1990, 8:127-140.
4. Sischo W.M., Hird D.W., Gardner L.A., et al. Economics of disease occurrence and prevention on California dairy farms: a report and evaluation of data collected for the National Animal Health Monitoring System, 1986-1987. Prev Vet Med 1990, 8:141-156.
5. Donovan G.A., Dohoo I.R., Montgomery D.M., et al. Calf and disease factors affecting growth in female Holstein calves in Florida, USA. Prev Vet Med 1998, 33:1-10.
6. Bach A., Ahedo J., Kertz A. Using growth monitoring in heifer management and research [abstract]. J Dairy Sci 2008, 91(E-Suppl 1):602.
7. Waltner-Toews D., Martin S.W., Meek A.H. The effect to early calfhood disease on survivorship and age at first calving. Can J Vet Res 1986, 50:314-317.
8. Correa M.T., Curtis C.R., Erb H.N., et al. Effect of calfhood morbidity on age at first calving in New York Holstein herd. Prev Vet Med 1988, 6:253-262.
9. USDA. Dairy 2007, Part I: reference of dairy cattle health and management practices in the United States, 2007 Fort Collins (CO): USDA-APHIS-VS, CEAH; 2007 #N480.1007.
10. Miller G.Y., Dorn C.R. Costs of dairy cattle diseases to producers in Ohio. Prev Vet Med 1990, 8:171-182.
11. Van Donkersgoed J., Ribble C., Boyer L.G., et al. Epidemiological study of enzootic pneumonia in dairy calves in Saskatchewan. Can J Vet Res 1993, 57:247-254.
12. Blom J.Y. The relationship between serum immunoglobulin values and incidence of respiratory disease and enteritis in calves. Nord Vet Med 1982, 34:276-284.
13. Thomas L.H., Swann R.G. Influence of colostrum on the incidence of calf pneumonia. Vet Rec 1973, 92:454-455.
14. Williams M.R., Spooner R.L., Thomas L.H. Quantitative studies on bovine immunoglobulins. Vet Rec 1975, 96:81-84.
15. Davidson J.N., Yancey S.P., Campbell S.G., et al. Relationship between serum immunoglobulin values and incidence of respiratory disease in calves. J Am Vet Med Assoc 1981, 179:708-710.
16. Corbeil L.B., Watt B., Corbeil R.R., et al. Immunoglobulin concentrations in serum and nasal secretions of calves at the onset of pneumonia. Am J Vet Res 1984, 45:773-778.
17. Virtala A.M., Grohn Y.T., Mechor G.D., et al. The effect of maternally derived immunoglobulin G on the risk of respiratory disease in heifers during the first 3 months of life. Prev Vet Med 1999, 39:25-37.
18. USDA. Dairy 2007, Heifer calf health and management practices on U.S. dairy operations, 2007. Fort Collins (CO): USDA: APHIS:VS, CEAH; 2010 #550.0110.
19. Villarroel A., Dargatz D.A., Lane V.M., et al. Suggested outline of potential critical control points for biosecurity and biocontainment on large dairy farms. J Am Vet Med Assoc 2007, 230:808-819.
20. Poulsen KP, Hartmann FA, McGuirk SM. Bacteria in colostrum: impact on calf health. In: Proceedings of the 2002 American College of Veterinary Internal Medicine Forum, Dallas (TX). Ontario (CA): Content Management Corp 2002. p. 773.
21. Stewart S., Godden S., Bey R., et al. Preventing bacterial contamination and proliferation during the harvest, storage, and feeding of fresh bovine colostrum. J Dairy Sci 2005, 88:2571-2578.
22. McGuirk S.M., Collins M. Managing the production, storage, and delivery of colostrum. Vet Clin North Am Food Anim Pract 2004, 20:593-603.
23. Godden S. Colostrum management for dairy calves. Vet Clin North Am Food Anim Pract 2008, 24:19-39.
24. Quirk Z, West J, Gorden PJ. Efficacy of formic acid as a means of controlling Mycoplasma bovis and Mycobacterium avium subspecies paratuberculosis in dairy cattle. In: Proceedings of the 41st Annual Meeting of the American Association of Bovine Practitioners, Charlotte (NC). Stillwater (OK): Frontier Printers Inc 2008. p. 279.
25. Anderson N. Experiences with free-access acidified-milk feeding in Ontario. In: Proceedings of the 41st Annual Meeting of the American Association of Bovine Practitioners, Charlotte (NC). Stillwater (OK): Frontier Printers Inc, 2008. p. 12-24.
26. Godden S., McMartin S., Feirtag J., et al. Heat-treatment of bovine colostrum. II: effects of heating duration on pathogen viability and immunoglobulin G. J Dairy Sci 2006, 89:3476-3483.
27. Peterson J, Godden S, Bey R. Relationship between bacteria levels in colostrum and efficiency of absorption of immunoglobulin G in newborn dairy calves. In: Proceedings of the 41st Annual Meeting of the American Association of Bovine Practitioners, Charlotte (NC). Stillwater (OK): Frontier Printers Inc 2008. p. 248.
28. Donahue M, Godden S, Bey R, et al. Preliminary results on the effect of feeding heat-treated colostrum on health and growth in pre-weaned dairy calves. In: Proceedings of the 42nd Annual Meeting of the American Association of Bovine Practitioners, Omaha (NE). Stillwater (OK): VM Publishing Co 2009. p. 187.
29. Bovine Alliance on Management and Nutrition A guide to colostrum and colostrum management for dairy calves revision. Available at:, Accessed January, 2010. http://www.aphis.usda.gov/vs/ceah/ncahs/nahms/dairy/bamn/BAMNColostrum.pdf.
30. Molla A. Immunoglobulin levels in calves fed colostrum by stomach tube. Vet Rec 1978, 103:377-380.
31. Adams G.D., Bush L.J., Horner J.L., et al. Two methods for administering colostrum to newborn calves. J Dairy Sci 1985, 68:773-775.
32. Besser T.E., Gay C.C., Pritchett L. Comparison of three methods of feeding colostrum to dairy calves. J Am Vet Med Assoc 1991, 198:419-422.
33. Lochmiller R.H., Deerenberg C. Trade-offs in evolutionary immunology: just what is the cost of immunity?. Oikos 2000, 88(1):87-98.
34. Godden S.M., Fetrow J.P., Feirtag J.M., et al. Economic analysis of feeding pasteurized nonsaleable milk versus conventional milk replacer to dairy calves. J Am Vet Med Assoc 2005, 226(9):1547-1554.
35. Nonnencke B.J., Foote M.R., Miller B.L., et al. Effects of chronic environmental cold on growth, health, and select metabolic and immunologic responses of pre-ruminant calves. J Dairy Sci 2009, 92:6134-6143.
36. Callan R.J., Garry F.B. Biosecurity and bovine respiratory disease. Vet Clin North Am Food Anim Pract 2002, 18:57-77.
37. Butler J.A., Sickles S.A., Johanns C.J., et al. Pasteurization of discard Mycoplasma mastitic milk used to feed calves: thermal effects on various Mycoplasma. J Dairy Sci 2000, 83:2285-2288.
38. Stabel J.R., Hurd S., Calvente L., et al. Destruction of Mycobacterium paratuberculosis, Salmonella spp and Mycoplasma spp in raw milk by a commercial on-farm high-temperature, short-time pasteurization. J Dairy Sci 2004, 87(7):2177-2183.
39. Woolums A.R., Ames T.R., Baker J.C. The bronchopneumonias (respiratory disease complex of cattle, sheep, and goats). Large animal internal medicine 2007, 602-652. Mosby Elsevier, St. Louis (MO). 4th edition. B.P. Smith (Ed.).
40. Lago A., McGuirk S.M., Bennett T.B., et al. Calf respiratory disease and pen microenvironments in naturally ventilated calf barns in winter. J Dairy Sci 2006, 89:4014-4025.
41. Maunsell F., Donovan G.A. Biosecurity and risk management for dairy replacements. Vet Clin North Am Food Anim Pract 2008, 24:155-190.
42. Federation of Animal Science Societies. Dairy cattle. In: Guide for the care and use of agricultural animals in teaching and research. 3rd edition. Champagne (IL): Federation of Animal Science Societies 2010. p. 74-88.
43. Webster J. Environmental needs. Calf husbandry, health and welfare 1984, 71-97. Westview, Boulder (CO).
44. Pritchard D.G., Carpenter G.A., Morzaria S.P., et al. Effect of air filtration on respiratory disease in intensively housed veal calves. Vet Rec 1981, 109:5-9.
45. Hillman P., Gebremedhin K., Warner R. Ventilation system to minimize airborne bacteria, dust, humidity, and ammonia in calf nurseries. J Dairy Sci 1992, 75:1305-1312.
46. Blom J.Y., Madsen E.B., Krogh H.V., et al. Numbers of airborne bacteria and fungi in calf houses. Nord Vet Med 1984, 36:215-220.
47. Wathes C.M., Howard K., Jones C.D.R., et al. The balance of airborne bacteria in calf houses. J Agric Eng Res 1984, 30:81-90.
48. Eduard W., Heederik D. Methods for quantitative assessment of airborne levels of noninfectious microorganisms in highly contaminated work environments. Am Ind Hyg Assoc J 1998, 59:113-127.
49. Nordlund K. Practical considerations for ventilating calf barns in winter. In: Proceedings of 40th Annual Meeting of the American Association of Bovine Practitioners-Preconference Seminar 7B, Vancouver. Stillwater (OK): Frontier Printers Inc, 2007. p. 85-93.
50. Maatje K., Verhoeff J., Kremer W.D.J., et al. Automated feeding of milk replacer and health control of group-housed veal calves. Vet Rec 1993, 133:266-270.
51. Svensson C., Liberg P. The effect of group size on health and growth rate of Swedish dairy calves housed in pens with automatic milk-feeders. Prev Vet Med 2006, 73:43-53.
52. Willard C., Losinger M.S., Heinrichs A.J. Management variables associated with high mortality rates attributable to respiratory-tract problems in female calves prior to weaning. J Am Vet Med Assoc 1996, 209:1756-1759.
53. Nardell E.A., Keegan J., Cheney S.A., et al. Airborne infection: Theoretical limits of protection achievable by building ventilation. Am Rev Respir Dis 1991, 144:302-306.
54. Wathes C.M., Jones C.D., Webster A.J. Ventilation, air hygiene and animal health. Vet Rec 1983, 113:554-559.
55. Bates D.W., Anderson J.F. Calculation of ventilation needs for confined cattle. J Am Vet Med Assoc 1979, 174(6):581-589.
56. Bach A., Ahedo J., Ferrer A. Optimizing weaning strategies of dairy replacement calves. J Dairy Sci 2010, 93(1):413-419.
57. Quigley J. Calf Note #16-Stress at weaning Available at:, Accessed February, 2010. http://www.calfnotes.com.
58. Ziegler D., Ziegler B., Raeth-Knight M., et al. Performance of post weaned Holstein heifer calves transitioned to group housing using different management strategies while fed a common diet [abstract TH191]. J Dairy Sci 2008, 91(E-Suppl 1). F.
59. McGuirk S.M. Disease management of dairy calves and heifers. Vet Clin North Am Food Anim Pract 2008, 24:139-153.
60. Stanton A.L., Kelton D.F., LeBlanc S.J., et al. The effect of treatment with long-acting antibiotic at postweaning movement on respiratory disease and on growth in commercial dairy calves. J Dairy Sci 2010, 93(1):574-581.
61. Chase C.L., Hurley D.J., Reber A.J. Neonatal immune development in the calf and its impact on vaccine response. Vet Clin North Am Food Anim Pract 2008, 24:87-104.
62. Platt R., Widel P.W., Kesl L.D., et al. Comparison of humoral and cellular immune responses to a pentavalent modified live virus vaccine in three age groups of calves with maternal antibodies, before and after BVDV type 2 challenge. Vaccine 2009, 27:4508-4519.
63. Cortese V. Bovine vaccines and herd vaccination programs. Large animal internal medicine 2007, 1591-1603. Mosby Elsevier, St. Louis (MO). 4th edition. B.P. Smith (Ed.).
64. Shelton T, Hoffman B. Determining the prevalence of bovine viral diarrhea virus persistently infected calves originating from a number of modern western well-vaccinated dairy herds In: Proceedings of the 42nd Annual Meeting of the American Association of Bovine Practitioners, Omaha (NE). Stillwater (OK): VM Publishing Co 2009. p. 182.
65. Angen O., Thomsen J., Larsen L.E., et al. Respiratory disease in calves: microbiological investigations on trans-tracheally aspirated bronchoalveolar fluid and acute phase protein response. Vet Microbiol 2009, 137:165-171.
66. Smith S. BVD control for the dairy practitioner: Strategies and implementation. In: Proceedings of the 42nd Annual Meeting of the American Association of Bovine Practitioners, Omaha (NE). Stillwater (OK): VM Publishing Co 2009. p. 98-102.
67. Baker J.C., Werdin R.E., Ames T.R., et al. Study on the etiologic role of bovine respiratory syncytial virus in pneumonia of dairy calves. J Am Vet Med Assoc 1986, 189:66-70.
68. Godinho K.S., Sarasola P., Renoult E., et al. Use of deep nasopharyngeal swabs as a predictive diagnostic method for natural respiratory infections in calves. Vet Rec 2007, 160:22-25.
69. Kimura K., Goff J.P., Kehrli M.E. Effects of the presence of the mammary gland on expression of neutrophil adhesion molecules and myeloperoxidase activity in periparturient dairy cows. J Dairy Sci 1999, 82:2385-2392.
70. Kehrli M.E., Nonnecke B.J., Roth J.A. Alterations in bovine neutrophil function during the periparturient period. Am J Vet Res 1989, 50(2):207-214.
71. Kehrli M.E., Nonnecke B.J., Roth J.A. Alterations in bovine lymphocyte function during the periparturient period. Am J Vet Res 1989, 50(2):215-220.
72. Kimura K., Goff J.P., Kehrli M.E., et al. Effects of mastectomy on composition of peripheral blood mononuclear cell populations in periparturient dairy cows. J Dairy Sci 2002, 85:1437-1444.
73. + suppressor lymphocytes alter immune responsiveness during the postpartum period. Vet Immunol Immunopathol 1997, 56:53-64.
74. Goff J.P., Horst R.L. Physiological changes at parturition and their relationship to metabolic disorders. J Dairy Sci 1997, 80(1):176-186.
75. Perkins K.H., VandeHaar J.M., Burton J.L., et al. Clinical responses to intramammary endotoxin infusion in dairy cows subjected to feed restriction. J Dairy Sci 2002, 85:1724-1731.
76. Moyes K.M., Drackley J.K., Salak-Johnson J.L., et al. Dietary-induced negative energy balance has minimal effects on innate immunity during a Streptococcus uberis mastitis challenge in dairy cows during mid-lactation. J Dairy Sci 2009, 92:4301-4316.
77. Kremer W.D., Noordhuizen-Stassen E.N., Grommers F.J., et al. Severity of experimental Escherichia coli mastitis in ketonemic and nonketonemic dairy cows. J Dairy Sci 1993, 76:3428-3436.
78. Kimura K., Reinhardt T.A., Goff J.P. Parturition and hypocalcemia blunts calcium signals in immune cells of dairy cattle. J Dairy Sci 2006, 89:2588-2595.
79. National Research Council. Dry matter intake. In: Nutrient requirements of dairy cattle. 7th edition. Washington, DC: National Academy Press 2001. p. 3-12.
80. Collier R.J., Dahl G.E., VanBaale M.J. Major advances associated with environmental effects on dairy cattle. J Dairy Sci 2006, 89:1244-1253.
81. Kleen J.L., Hooijer G.A., Rehage J., et al. Subacute rumen acidosis (SARA): a review. J Vet Med A Physiol Pathol Clin Med 2003, 50:406-414.
82. Whitlow L. Mold and mycotoxin issues in dairy cattle: effects, prevention, and treatment Available at:, Accessed January, 2010. http://www.extension.org/pages/Mold_and_Mycotoxin%20Issues_in%20Dairy_Cattle:_Effects,_Prevention_and_Treatment.
83. Divers T.J. Respiratory disease. Rebhun's diseases of dairy cattle 2008, 78-129. Saunders Elsevier, St. Louis (MO). 2nd edition. T.J. Divers, S.F. Peek (Eds.).
84. Midwest Plan Service Mechanical ventilating systems for livestock housing 1990, Midwest Plan Services-32. Iowa State University, Ames (IA), 50011. 1st edition.
85. Brouk MJ, Smith JF, Harner III JP. Managing the cow environment for improved animal health and milk quality. In: NMC 43rd Annual Meeting Proceedings, Charlotte (NC). Madison (WI): Omnipress 2004. p. 271-81.