Parturition and hypocalcemia blunts calcium signals in immune cells of dairy cattle

Journal of Dairy Science

Volumn 89, Issue 7, 2006, Pages 2588-2595

  Kimura, K ^a   Reinhardt, T A ^a   Goff, J P ^a  

^a NATIONAL ANIMAL DISEASE CENTER   (United States)

Author keywords

Endoplasmic reticulum; Flow cytometry; Immunosuppression; Signal transduction

Indexed keywords

ANIMALIA; BOS TAURUS;

EID: 33745894154     PISSN: 00220302     EISSN: None     Source Type: Journal    
DOI: 10.3168/jds.S0022-0302(06)72335-9     Document Type: Article

References (34)

1. Allen, M. E., S. P. Young, R. H. Michell, and P. A. Bacon. 1995. Altered T lymphocyte signaling in rheumatoid arthritis. Eur. J. Immunol. 25:1547-1554.
2. Baus, E., F. Andris, P. M. Dubois, J. Urbain, and O. Leo. 1996. Dexamethasone inhibits the early steps of antigen receptor signaling in activated T lymphocytes. J. Immunol. 156:4555-4561.
3. Burton, J. L., and M. E. Kehrli, Jr. 1995. Regulation of neutrophil adhesion molecules and shedding of Staphylococcus aureus in milk of cortisol-and dexamethasone-treated cows. Am. J. Vet. Res. 56:997-1006.
4. 2+ signaling in synovial fluid T lymphocytes from patients with chronic inflammatory arthritis. Arthritis Rheum. 43:1257-1265.
5. Carruthers, D. M., W. G. Naylor, M. E. Allen, G. D. Kitas, P. A. Bacon, and S. P. Young. 1996. Characterization of altered calcium signalling in T lymphocytes from patients with rheumatoid arthritis (RA). Clin. Exp. Immunol. 105:291-296.
6. Chiodini, R. J., H. J. Van Kruiningen, and R. S. Merkal. 1984. Ruminant paratuberculosis (Johne's disease): The current status and future prospects. Cornell Vet. 74:218-262.
7. Curtis, C. R., H. N. Erb, C. J. Sniffen, R. D. Smith, P. A. Powers, M. C. Smith, M. E. White, R. B. Hillman, and E. J. Pearson. 1983. Association of parturient hypocalcemia with eight periparturient disorders in Holstein cows. J. Am. Vet. Med. Assoc. 183:559-561.
8. Duffield, T., S. L. E. Blanc, and K. Leslie. 2005. Impact of subclinical metabolic disease on risk of early lactation culling. J. Dairy Sci. 88(Suppl. 1):199-200. (Abstr.)
9. Fantus, I. G., S. Kadota, G. Deragon, B. Foster, and B. I. Posner. 1989. Pervanadate [peroxide(s) of vanadate] mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase. Biochemistry 28:8864-8871.
10. Fossler, C. P., S. J. Wells, J. B. Kaneene, P. L. Ruegg, L. D. Warnick, L. E. Eberly, S. M. Godden, L. W. Halbert, A. M. Campbell, C. A. Bolin, and A. M. Zwald. 2005. Cattle and environmental sample-level factors associated with the presence of Salmonella in a multi-state study of conventional and organic dairy farms. Prev. Vet. Med. 67:39-53.
11. Gascon-Barre, M., P. Haddad, S. J. Provencher, S. Bilodeau, F. Pecker, S. Lotersztajn, and S. Vallierses. 1994. Chronic hypocalcemia of vitamin d deficiency leads to lower intracellular calcium concentrations in rat hepatocytes. J. Clin. Invest. 93:2159-2167.
12. Gascon-Barre, M., J.-L. Petit, C. Ethier, and S. Bilodeau. 1997. Hypocalcemia modifies the intracellular calcium response to the β1-adrenergic agent phenylephrine in rat hepatocytes. Cell Calcium 22:343-356.
13. Goff, J. P., and R. L. Horst. 1997. Physiological changes at parturition and their relationship to metabolic disorders. J. Dairy Sci. 80:1260-1268.
14. Goff, J. P., and K. Kimura. 2002. Effect of mastectomy on milk fever, energy, and vitamins A, E, and β-carotene status at parturition. J. Dairy Sci. 85:1427-1436.
15. Grafton, G., and L. Thwaite. 2001. Calcium channels in lymphocytes. Immunology 104:119-126.
16. Kadota, S., I. G. Fantus, G. Deragon, H. J. Guyda, and B. I. Posner. 1987. Stimulation of insulin-like growth factor II receptor binding and insulin receptor kinase activity in rat adipocytes. J. Biol. Chem. 262:8252-8256.
17. Kehrli, M. E., Jr., and J. P. Goff. 1989. Periparturient hypocalcemia in cows: Effects on peripheral blood neutrophil and lymphocyte function. J. Dairy Sci. 72:1188-1196.
18. Kehrli, M. E., Jr., B. J. Nonnecke, and J. A. Roth. 1989a. Alterations in bovine lymphocyte function during the periparturient period. Am. J. Vet. Res. 50:215-220.
19. Kehrli, M. E., Jr., B. J. Nonnecke, and J. A. Roth. 1989b. Alterations in bovine neutrophil function during the periparturient period. Am. J. Vet. Res. 50:207-214.
20. Kimura, K., J. P. Goff, M. E. Kehrli, Jr., and J. A. Harp. 1999. Pheno-type analysis of peripheral blood mononuclear cells in periparturient dairy cows. J. Dairy Sci. 82:315-319.
21. Kurosaki, T. 1999. Genetic analysis of B cell antigen receptor signaling. Annu. Rev. Immunol. 17:555-592.
22. Lewis, R. S. 2001. Calcium signaling mechanisms in T lymphocytes. Annu. Rev. Immunol. 19:497-521.
23. Mailhot, G., J.-L. Petit, C. Demers, and M. Gascon-Barre. 2000. Influence of the in vivo calcium status on cellular calcium homeostasis and the level of the calcium-binding protein calreticulin in rat hepatocytes. Endocrinology 141:891-900.
24. Nonnecke, B. J., K. Kimura, J. P. Goff, J. Marcus, and E. Kehrli. 2003. Effects of the mammary gland on functional capacities of blood mononuclear leukocyte populations from periparturient cows. J. Dairy Sci. 86:2359-2368.
25. Oishi, H., S. Budel, A. Shuster, N. Stergiopulos, J. J. Meister, and J. L. Beny. 2001. Cytosolic-free calcium in smooth-muscle and endothelial cells in an intact arterial wall from rat mesenteric artery in vitro. Cell Calcium 30:261-267.
26. Partiseti, M., F. L. Deist, C. Hivroz, A. Fisher, H. Korn, and D. Choquet. 1994. The calcium current activated by T cell receptor and store depletion in human lymphocytes is absent in a primary immunodeficiency. J. Biol. Chem. 269:32327-32335.
27. Perkin-Elmer. 1965. Analytical methods for atomic absorption spectrophotometry. Perkin-Elmer Corp., Norwalk, CT.
28. Reinhardt, T. A., R. L. Horst, and J. P. Goff. 1988. Calcium, phosphorus, and magnesium homeostasis in ruminants. Vet. Clin. North Am. Food Anim. Pract. 4:331-350.
29. Roderick, H. L., D. H. Llewellyn, A. K. Campbell, and J. M. Kendall. 1998. Role of calreticulin in regulating intracellular Ca2+ storage and capacitative Ca2+ entry in HeLa cells. Cell Calcium 24:253-262.
30. 2+-ATPases in fractionated pig brain membranes using calcium pump inhibitors. Arch. Biochem. Biophys. 351:272-278.
31. Schieven, G. L., and J. A. Ledbetter. 1994. Activation of tyrosine kinase signal pathways by radiation and oxidative stress. Trends Endocrinol. Metab. 5:383-388.
32. Telford, W. G., and R. A. Miller. 1996. Detection of plasma membrane Ca2+-ATPase activity in mouse T lymphocytes by flow cytometry using Fluo-3-loaded vesicles. Cytometry 24:243-250.
33. Tsien, R. Y. 1981. A non-disruptive technique for loading calcium buffers and indicators into cells. Nature 290:527-528.
34. Vassilopoulos, D., R. B. Zurier, R. G. Rossetti, and G. C. Tsokos. 1997. Gammalinolenic acid and dihomogammalinolenic acid suppress the CD3-mediated signal transduction pathway in human T cells. Clin. Immunol. Immunopathol. 83:237-244.