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Volumn 411, Issue 17-18, 2010, Pages 1165-1171

Uveitis: Mechanisms and recent advances in therapy

Author keywords

Cytokine; Gene therapy; Intraocular inflammation; Uveitis

Indexed keywords

ADENOVIRUS VECTOR; ETANERCEPT; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; INFLIXIMAB; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; LENTIVIRUS VECTOR; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RECOMBINANT INTERLEUKIN 10; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 77954141742     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2010.04.017     Document Type: Review
Times cited : (30)

References (71)
  • 3
    • 0032077895 scopus 로고    scopus 로고
    • Involvement of TNF-α, IL-1beta and IL-1 receptor antagonist in LPS induced rabbit uveitis
    • Mo J.S., Matsukawa A., Ohkawara S., Yoshinaga M. Involvement of TNF-α, IL-1beta and IL-1 receptor antagonist in LPS induced rabbit uveitis. Exp Eye Res 1998, 66:547-557.
    • (1998) Exp Eye Res , vol.66 , pp. 547-557
    • Mo, J.S.1    Matsukawa, A.2    Ohkawara, S.3    Yoshinaga, M.4
  • 4
    • 0023176764 scopus 로고
    • Inflammatory responses to intraocularly injected interleukin-1
    • Bhattacherjee P., Henderson B. Inflammatory responses to intraocularly injected interleukin-1. Curr Eye Res 1987, 6:929-934.
    • (1987) Curr Eye Res , vol.6 , pp. 929-934
    • Bhattacherjee, P.1    Henderson, B.2
  • 6
    • 0032408878 scopus 로고    scopus 로고
    • Basic pathogenic mechanisms operating in experimental models of acute anterior uveitis
    • Smith J.R., Hart P.H., Williams K.A. Basic pathogenic mechanisms operating in experimental models of acute anterior uveitis. Immunol Cell Biol 1998, 76:497-512.
    • (1998) Immunol Cell Biol , vol.76 , pp. 497-512
    • Smith, J.R.1    Hart, P.H.2    Williams, K.A.3
  • 7
    • 42449114080 scopus 로고    scopus 로고
    • Relevance of animal models to human uveitis
    • Bodaghi B., Rao N. Relevance of animal models to human uveitis. Ophthalmic Res 2008, 40:200-202.
    • (2008) Ophthalmic Res , vol.40 , pp. 200-202
    • Bodaghi, B.1    Rao, N.2
  • 8
    • 0041875007 scopus 로고    scopus 로고
    • Chemokine-their role in immunotherapy for intraocular inflammation
    • Kwashima H. Chemokine-their role in immunotherapy for intraocular inflammation. Ocul Immunol Inflamm 2003, 11:83-90.
    • (2003) Ocul Immunol Inflamm , vol.11 , pp. 83-90
    • Kwashima, H.1
  • 9
    • 17744387550 scopus 로고    scopus 로고
    • TNF-α inhibitors in the treatment of uveitis
    • Greiner K., Plskova J. TNF-α inhibitors in the treatment of uveitis. Ophthalmologe 2005, 102:335-340.
    • (2005) Ophthalmologe , vol.102 , pp. 335-340
    • Greiner, K.1    Plskova, J.2
  • 10
    • 0028097369 scopus 로고
    • Expression of multiple cytokines and IL-1RA in the uvea and retina during endotoxin-induced uveitis in the rat
    • De Vos A.F., Klaren V.N., Kijlstra A. Expression of multiple cytokines and IL-1RA in the uvea and retina during endotoxin-induced uveitis in the rat. Invest Ophthalmol Vis Sci 1994, 35:3873-3883.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 3873-3883
    • De Vos, A.F.1    Klaren, V.N.2    Kijlstra, A.3
  • 11
    • 0031850685 scopus 로고    scopus 로고
    • Intraocular cytokine quantification of experimental autoimmune uveoretinitis in rats
    • Okada A.A., Sakai J., Usui M., Mizuguchi J.J. Intraocular cytokine quantification of experimental autoimmune uveoretinitis in rats. Ocul Immunol Inflamm 1998, 6:111-120.
    • (1998) Ocul Immunol Inflamm , vol.6 , pp. 111-120
    • Okada, A.A.1    Sakai, J.2    Usui, M.3    Mizuguchi, J.J.4
  • 13
    • 0031820107 scopus 로고    scopus 로고
    • Neutralizing TNF-α activity modulates T-cell phenotype function in experimental autoimmune uveoretinitis
    • Dick A.D., Duncan L., Hale G., Waldmann H., Isaacs J. Neutralizing TNF-α activity modulates T-cell phenotype function in experimental autoimmune uveoretinitis. J Autoimmun 1998, 11:255-264.
    • (1998) J Autoimmun , vol.11 , pp. 255-264
    • Dick, A.D.1    Duncan, L.2    Hale, G.3    Waldmann, H.4    Isaacs, J.5
  • 14
    • 0038576873 scopus 로고    scopus 로고
    • Neutralizing tumor necrosis factor-α activity suppresses activation of infiltrating macrophages in experimental autoimmune uveoretinitis
    • Robertson M., Liversidge J., Forrester J.V., Andrew D.D. Neutralizing tumor necrosis factor-α activity suppresses activation of infiltrating macrophages in experimental autoimmune uveoretinitis. Invest Ophthalmol Vis Sci 2003, 44:3034-3041.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 3034-3041
    • Robertson, M.1    Liversidge, J.2    Forrester, J.V.3    Andrew, D.D.4
  • 17
    • 0031029814 scopus 로고    scopus 로고
    • Systemic levels of the T cell regulatory cytokines IL-10 and IL-12 in Behcet's disease; soluble TNFR-75 as a biological marker of disease activity
    • Turan B., Gallati H., Erdi H., Gurler A., Michel B.A., Villiger P.M., et al. Systemic levels of the T cell regulatory cytokines IL-10 and IL-12 in Behcet's disease; soluble TNFR-75 as a biological marker of disease activity. J Rheumatol 1997, 24:128-132.
    • (1997) J Rheumatol , vol.24 , pp. 128-132
    • Turan, B.1    Gallati, H.2    Erdi, H.3    Gurler, A.4    Michel, B.A.5    Villiger, P.M.6
  • 18
    • 0033524159 scopus 로고    scopus 로고
    • Infliximab (chimeric anti-tumour necrosis factor-alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial
    • Maini R., St Clair E.W., Breedveld F., Frust D., Kalden J., Weisman M., et al. Infliximab (chimeric anti-tumour necrosis factor-alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. Lancet 1999, 354:1932-1939.
    • (1999) Lancet , vol.354 , pp. 1932-1939
    • Maini, R.1    St Clair, E.W.2    Breedveld, F.3    Frust, D.4    Kalden, J.5    Weisman, M.6
  • 19
    • 0034039605 scopus 로고    scopus 로고
    • Chimeric anti-tumor necrosis factor-α monoclonal antibody treatment of patients with rheumatoid arthritis receiving methotrexate therapy.
    • Kavanaugh A., St Clair E.W., McCune W.J., Braakman T., Lipsky P. Chimeric anti-tumor necrosis factor-α monoclonal antibody treatment of patients with rheumatoid arthritis receiving methotrexate therapy. J Rheumatol 2000, 27:841-850.
    • (2000) J Rheumatol , vol.27 , pp. 841-850
    • Kavanaugh, A.1    St Clair, E.W.2    McCune, W.J.3    Braakman, T.4    Lipsky, P.5
  • 20
    • 0033125226 scopus 로고    scopus 로고
    • Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety
    • Sandborn W.J., Hanauer S.B. Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety. Inflamm Bowel Dis 1999, 5:119-133.
    • (1999) Inflamm Bowel Dis , vol.5 , pp. 119-133
    • Sandborn, W.J.1    Hanauer, S.B.2
  • 21
    • 0037379801 scopus 로고    scopus 로고
    • Infliximab treatment of sarcoidosis
    • Serio R.N. Infliximab treatment of sarcoidosis. Ann Pharmacother 2003, 37:577-581.
    • (2003) Ann Pharmacother , vol.37 , pp. 577-581
    • Serio, R.N.1
  • 22
    • 0037029430 scopus 로고    scopus 로고
    • Treatment of active ankylosing spondylitis with infliximab: randomised controlled multicentre trial
    • Braun J., Brandt J., Listing J., Zink A., Alten R., Golder W., et al. Treatment of active ankylosing spondylitis with infliximab: randomised controlled multicentre trial. Lancet 2002, 359:1187-1193.
    • (2002) Lancet , vol.359 , pp. 1187-1193
    • Braun, J.1    Brandt, J.2    Listing, J.3    Zink, A.4    Alten, R.5    Golder, W.6
  • 23
    • 0035083651 scopus 로고    scopus 로고
    • Treatment of psoriatic arthritis with antitumour necrosis factor-α antibody clears skin lesions of psoriasis resistant to treatment with methotrexate
    • Ogilvie A.L., Antoni C., Dechant C., Manger B., Kalden J.R., Schuler G., et al. Treatment of psoriatic arthritis with antitumour necrosis factor-α antibody clears skin lesions of psoriasis resistant to treatment with methotrexate. Br J Dermatol 2001, 144:587-589.
    • (2001) Br J Dermatol , vol.144 , pp. 587-589
    • Ogilvie, A.L.1    Antoni, C.2    Dechant, C.3    Manger, B.4    Kalden, J.R.5    Schuler, G.6
  • 24
    • 0036233794 scopus 로고    scopus 로고
    • Treatment of recalcitrant psoriatic arthritis with anti-tumor necrosis factor-alpha antibody
    • Wollina U., Konrad H. Treatment of recalcitrant psoriatic arthritis with anti-tumor necrosis factor-alpha antibody. J Eur Acad Dermatol Venereol 2002, 16:127-129.
    • (2002) J Eur Acad Dermatol Venereol , vol.16 , pp. 127-129
    • Wollina, U.1    Konrad, H.2
  • 26
    • 0036897465 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-α therapy with infliximab as an alternative to corticosteroids in the treatment of human leukocyte antigen B27-associated acute anterior uveitis
    • El-Shabrawi Y., Hermann J. Anti-tumor necrosis factor-α therapy with infliximab as an alternative to corticosteroids in the treatment of human leukocyte antigen B27-associated acute anterior uveitis. Ophthalmology 2002, 109:2342-2346.
    • (2002) Ophthalmology , vol.109 , pp. 2342-2346
    • El-Shabrawi, Y.1    Hermann, J.2
  • 27
    • 0034796250 scopus 로고    scopus 로고
    • Differential efficacy of tumor necrosis factor inhibition in the management of inflammatory eye disease and associated rheumatic disease
    • Smith J.R., Levinson R.D., Holland G.N., Jabs D.A., Robinson M.R., Whitcup S.M., et al. Differential efficacy of tumor necrosis factor inhibition in the management of inflammatory eye disease and associated rheumatic disease. Arthritis Rheum 2001, 45:252-257.
    • (2001) Arthritis Rheum , vol.45 , pp. 252-257
    • Smith, J.R.1    Levinson, R.D.2    Holland, G.N.3    Jabs, D.A.4    Robinson, M.R.5    Whitcup, S.M.6
  • 29
    • 0035960624 scopus 로고    scopus 로고
    • Onset of multiple sclerosis associated with anti-TNF therapy
    • Sicotte N.L., Voskuhl R.R. Onset of multiple sclerosis associated with anti-TNF therapy. Neurology 2001, 57:1885-1888.
    • (2001) Neurology , vol.57 , pp. 1885-1888
    • Sicotte, N.L.1    Voskuhl, R.R.2
  • 32
    • 0036822552 scopus 로고    scopus 로고
    • Life-threatening histoplasmosis complicating immunotherapy with tumour necrosis factor α antagonists infliximab and etanercept
    • Lee J.H., Slifman N.R., Gershon S.K., Edwards E.T., Schwieterman W.D., Seigel J.N., et al. Life-threatening histoplasmosis complicating immunotherapy with tumour necrosis factor α antagonists infliximab and etanercept. Arthritis Rheum 2002, 46:2565-2570.
    • (2002) Arthritis Rheum , vol.46 , pp. 2565-2570
    • Lee, J.H.1    Slifman, N.R.2    Gershon, S.K.3    Edwards, E.T.4    Schwieterman, W.D.5    Seigel, J.N.6
  • 34
    • 69249238444 scopus 로고    scopus 로고
    • Immunotherapy of uveitis: is gene therapy in our future?
    • Springer Berlin Heidelberg, U. Pleyer, C.S. Foster (Eds.)
    • Caspi R.R. Immunotherapy of uveitis: is gene therapy in our future?. Uveitis and immunological disorders 2007, 193-210. Springer Berlin Heidelberg. U. Pleyer, C.S. Foster (Eds.).
    • (2007) Uveitis and immunological disorders , pp. 193-210
    • Caspi, R.R.1
  • 35
    • 30544453442 scopus 로고    scopus 로고
    • Inhibition of experimental autoimmune anterior uveitis by adenovirus-mediated transfer of the interleukin-10 gene
    • Fang I.M., Lin C.P., Yang C.H., Chiang B.L., Yang C.M., Chan L.Y., et al. Inhibition of experimental autoimmune anterior uveitis by adenovirus-mediated transfer of the interleukin-10 gene. J Ocul Pharmacol Ther 2005, 21:420-428.
    • (2005) J Ocul Pharmacol Ther , vol.21 , pp. 420-428
    • Fang, I.M.1    Lin, C.P.2    Yang, C.H.3    Chiang, B.L.4    Yang, C.M.5    Chan, L.Y.6
  • 36
    • 55549121559 scopus 로고    scopus 로고
    • Lentiviral vector-mediated expression of murine IL-1 receptor antagonist or IL-10 reduces the severity of endotoxin-induced uveitis
    • Trittibach P., Barker S.E., Broderick C.A., Natkunarajah M., Duran Y., Robbie S.J., et al. Lentiviral vector-mediated expression of murine IL-1 receptor antagonist or IL-10 reduces the severity of endotoxin-induced uveitis. Gene Ther 2008, 15:1478-1488.
    • (2008) Gene Ther , vol.15 , pp. 1478-1488
    • Trittibach, P.1    Barker, S.E.2    Broderick, C.A.3    Natkunarajah, M.4    Duran, Y.5    Robbie, S.J.6
  • 38
    • 0032102995 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis
    • Apparailly F., Verwaerde C., Jacquet C., Auriault C., Sany J., Jorgensen C. Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis. J Immunol 1998, 160:5213-5220.
    • (1998) J Immunol , vol.160 , pp. 5213-5220
    • Apparailly, F.1    Verwaerde, C.2    Jacquet, C.3    Auriault, C.4    Sany, J.5    Jorgensen, C.6
  • 40
    • 22644445751 scopus 로고    scopus 로고
    • Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis
    • Broderick C.A., Smith A.J., Balaggan K.S., Georgiadis A., Buch P.K., Trittibach P.C., et al. Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis. Mol Ther 2005, 12:369-373.
    • (2005) Mol Ther , vol.12 , pp. 369-373
    • Broderick, C.A.1    Smith, A.J.2    Balaggan, K.S.3    Georgiadis, A.4    Buch, P.K.5    Trittibach, P.C.6
  • 41
    • 0036406868 scopus 로고    scopus 로고
    • Inhibition of experimental autoimmune uveoretinitis by systemic and subconjunctival adenovirus mediated transfer of the viral IL-10 gene
    • De Kozak Y., Thillaye-Goldenberg B., Naud M.C., Da Costa A.V., Auriault C., Verwaerde C. Inhibition of experimental autoimmune uveoretinitis by systemic and subconjunctival adenovirus mediated transfer of the viral IL-10 gene. Clin Exp Immunol 2002, 130:212-223.
    • (2002) Clin Exp Immunol , vol.130 , pp. 212-223
    • De Kozak, Y.1    Thillaye-Goldenberg, B.2    Naud, M.C.3    Da Costa, A.V.4    Auriault, C.5    Verwaerde, C.6
  • 42
    • 0036694645 scopus 로고    scopus 로고
    • The balance between IL-1 and IL-1Ra in disease
    • Arend W.P. The balance between IL-1 and IL-1Ra in disease. Cytokine Growth Factor Rev 2002, 13:323-340.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 323-340
    • Arend, W.P.1
  • 44
    • 0034130299 scopus 로고    scopus 로고
    • Therapy and prevention of arthritis by recombinant adeno-associated virus vector with delivery of interleukin-1 receptor antagonist
    • Pan R.Y., Chen S.L., Xiao X., Liu D.W., Peng H.J., Tsao Y.P. Therapy and prevention of arthritis by recombinant adeno-associated virus vector with delivery of interleukin-1 receptor antagonist. Arthritis Rheum 2000, 43:289-297.
    • (2000) Arthritis Rheum , vol.43 , pp. 289-297
    • Pan, R.Y.1    Chen, S.L.2    Xiao, X.3    Liu, D.W.4    Peng, H.J.5    Tsao, Y.P.6
  • 45
    • 0030031182 scopus 로고    scopus 로고
    • Pharmacokinetics and immunomodulatory properties of intravenously administered recombinant human interleukin-10 in healthy volunteers
    • Huhn R.D., Radwanski E., O'Connell S.M., Sturgill M.G., Clarke L., Cody R.P., et al. Pharmacokinetics and immunomodulatory properties of intravenously administered recombinant human interleukin-10 in healthy volunteers. Blood 1996, 87:699-705.
    • (1996) Blood , vol.87 , pp. 699-705
    • Huhn, R.D.1    Radwanski, E.2    O'Connell, S.M.3    Sturgill, M.G.4    Clarke, L.5    Cody, R.P.6
  • 46
    • 2342505985 scopus 로고    scopus 로고
    • A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer
    • Gouze J.N., Gouze E., Palmer G.D., Liew V.S., Pascher A., Betz O.B., et al. A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer. Arthritis Res Ther 2003, 5:R301-R309.
    • (2003) Arthritis Res Ther , vol.5
    • Gouze, J.N.1    Gouze, E.2    Palmer, G.D.3    Liew, V.S.4    Pascher, A.5    Betz, O.B.6
  • 47
    • 24944449409 scopus 로고    scopus 로고
    • Tetracycline-inducible viral interleukin-10 intraocular gene transfer, using adeno-associated virus in experimental autoimmune uveoretinitis
    • Smith J.R., Verwaerde C., Rolling F., Naud M.C., Delanoye A., Thillaye-Goldenberg B., et al. Tetracycline-inducible viral interleukin-10 intraocular gene transfer, using adeno-associated virus in experimental autoimmune uveoretinitis. Hum Gene Ther 2005, 16:1037-1046.
    • (2005) Hum Gene Ther , vol.16 , pp. 1037-1046
    • Smith, J.R.1    Verwaerde, C.2    Rolling, F.3    Naud, M.C.4    Delanoye, A.5    Thillaye-Goldenberg, B.6
  • 48
    • 68749105905 scopus 로고    scopus 로고
    • Suppression of experimental uveitis by a recombinant adeno-associated virus vector encoding interleukin-1 receptor antagonist
    • Tsai M.L., Horng C.T., Chen S.L., Xiao X., Wang C.H., Tsao Y.P. Suppression of experimental uveitis by a recombinant adeno-associated virus vector encoding interleukin-1 receptor antagonist. Mol Vis 2009, 1542-1552.
    • (2009) Mol Vis , pp. 1542-1552
    • Tsai, M.L.1    Horng, C.T.2    Chen, S.L.3    Xiao, X.4    Wang, C.H.5    Tsao, Y.P.6
  • 50
    • 0030926098 scopus 로고    scopus 로고
    • Topical interleukin-1 receptor antagonist promotes corneal transplant survival
    • Dana M.R., Yamada J., Streilein J.W. Topical interleukin-1 receptor antagonist promotes corneal transplant survival. Transplantation 1997, 63:1501-1507.
    • (1997) Transplantation , vol.63 , pp. 1501-1507
    • Dana, M.R.1    Yamada, J.2    Streilein, J.W.3
  • 51
    • 22844449524 scopus 로고    scopus 로고
    • Suppression of immune-mediated ocular inflammation in mice by interleukin-1 receptor antagonist administration
    • Lim W.K., Fujimoto C., Ursea R., Mahesh S.P., Silver P., Chan C.C., et al. Suppression of immune-mediated ocular inflammation in mice by interleukin-1 receptor antagonist administration. Arch Ophthalmol 2005, 123:957-963.
    • (2005) Arch Ophthalmol , vol.123 , pp. 957-963
    • Lim, W.K.1    Fujimoto, C.2    Ursea, R.3    Mahesh, S.P.4    Silver, P.5    Chan, C.C.6
  • 52
    • 0026552420 scopus 로고
    • Activity of an interleukin-1 receptor antagonist in rabbit models of uveitis
    • Rosenbaum J.T., Boney R.S. Activity of an interleukin-1 receptor antagonist in rabbit models of uveitis. Arch Ophthalmol 1992, 110:547-549.
    • (1992) Arch Ophthalmol , vol.110 , pp. 547-549
    • Rosenbaum, J.T.1    Boney, R.S.2
  • 53
    • 0028355564 scopus 로고
    • Herpes simplex viral vectors for therapeutic gene delivery to ocular tissues. Recent breakthroughs in the molecular genetics of ocular diseases
    • Pepose J.S., Leib D.A. Herpes simplex viral vectors for therapeutic gene delivery to ocular tissues. Recent breakthroughs in the molecular genetics of ocular diseases. Invest Ophthalmol Vis Sci 1994, 35:2662-2666.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 2662-2666
    • Pepose, J.S.1    Leib, D.A.2
  • 54
    • 0029887454 scopus 로고    scopus 로고
    • Ocular adenovirus gene transfer varies in efficiency and inflammatory response
    • Borras T., Tamm E.R., Zigler J.S. Ocular adenovirus gene transfer varies in efficiency and inflammatory response. Invest Ophthalmol Vis Sci 1996, 37:1282-1293.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 1282-1293
    • Borras, T.1    Tamm, E.R.2    Zigler, J.S.3
  • 55
    • 0031104792 scopus 로고    scopus 로고
    • Gene transfer by adeno-associated virus vectors into the central nervous system
    • Xiao X., Li J., McCown T.J., Samulski R.J. Gene transfer by adeno-associated virus vectors into the central nervous system. Exp Neurol 1997, 144:113-124.
    • (1997) Exp Neurol , vol.144 , pp. 113-124
    • Xiao, X.1    Li, J.2    McCown, T.J.3    Samulski, R.J.4
  • 56
    • 0029936764 scopus 로고    scopus 로고
    • Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors
    • Tripathy S.K., Black H.B., Goldwasser E., Leiden J.M. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nat Med 1996, 2:545-550.
    • (1996) Nat Med , vol.2 , pp. 545-550
    • Tripathy, S.K.1    Black, H.B.2    Goldwasser, E.3    Leiden, J.M.4
  • 57
    • 0034610364 scopus 로고    scopus 로고
    • Adeno-associated virus vector carrying human minidystrophin genes effectively ameliorates muscular dystrophy in mdx mouse model
    • Wang B., Li J., Xiao X. Adeno-associated virus vector carrying human minidystrophin genes effectively ameliorates muscular dystrophy in mdx mouse model. Proc Natl Acad Sci USA 2000, 97:13714-13719.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13714-13719
    • Wang, B.1    Li, J.2    Xiao, X.3
  • 58
    • 0141636324 scopus 로고    scopus 로고
    • Adeno-associated viral vectors for gene transfer and gene therapy
    • Bueler H. Adeno-associated viral vectors for gene transfer and gene therapy. Biol Chem 1999, 380:613-622.
    • (1999) Biol Chem , vol.380 , pp. 613-622
    • Bueler, H.1
  • 59
    • 0034960344 scopus 로고    scopus 로고
    • Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo
    • Nakai H., Yant S.R., Storm T.A., Fuess S., Meuse L., Kay M.A. Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo. J Virol 2001, 75:6969-6976.
    • (2001) J Virol , vol.75 , pp. 6969-6976
    • Nakai, H.1    Yant, S.R.2    Storm, T.A.3    Fuess, S.4    Meuse, L.5    Kay, M.A.6
  • 60
  • 61
    • 54549125880 scopus 로고    scopus 로고
    • Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potential
    • Li Q., Miller R., Han P.Y., Pang J., Dinculescu A., Chiodo V., et al. Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potential. Mol Vis 2008, 14:1760-1769.
    • (2008) Mol Vis , vol.14 , pp. 1760-1769
    • Li, Q.1    Miller, R.2    Han, P.Y.3    Pang, J.4    Dinculescu, A.5    Chiodo, V.6
  • 62
    • 1442354301 scopus 로고    scopus 로고
    • GDNF gene therapy attenuates retinal ischemic injuries in rats
    • Wu W.C., Lai C.C., Chen S.L., Sun M.H., Xiao X., Chen T.L., et al. GDNF gene therapy attenuates retinal ischemic injuries in rats. Mol Vis 2004, 10:93-102.
    • (2004) Mol Vis , vol.10 , pp. 93-102
    • Wu, W.C.1    Lai, C.C.2    Chen, S.L.3    Sun, M.H.4    Xiao, X.5    Chen, T.L.6
  • 63
    • 0032077895 scopus 로고    scopus 로고
    • Involvement of TNF-α, IL-1beta and IL-1 receptor antagonist in LPS induced rabbit uveitis
    • Mo J.S., Matsukawa A., Ohkawara S., Yoshinaga M. Involvement of TNF-α, IL-1beta and IL-1 receptor antagonist in LPS induced rabbit uveitis. Exp Eye Res 1998, 66:547-557.
    • (1998) Exp Eye Res , vol.66 , pp. 547-557
    • Mo, J.S.1    Matsukawa, A.2    Ohkawara, S.3    Yoshinaga, M.4
  • 64
    • 0028180443 scopus 로고
    • Interleukin-1α, interleukin-1beta, and tumor necrosis factor gene expression in endotoxin-induced uveitis
    • Yoshida M., Yoshimura N., Hangai M., Tanihara H., Honda Y. Interleukin-1α, interleukin-1beta, and tumor necrosis factor gene expression in endotoxin-induced uveitis. Invest Ophthalmol Vis Sci 1994, 35:1107-1113.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 1107-1113
    • Yoshida, M.1    Yoshimura, N.2    Hangai, M.3    Tanihara, H.4    Honda, Y.5
  • 65
    • 0034128106 scopus 로고    scopus 로고
    • Correlation of metalloproteinase-2 and -9 with proinflammatory cytokines interleukin-1beta, interleukin-12 and the interleukin-1 receptor antagonist in patients with chronic uveitis
    • El-Shabrawi Y.G., Christen W.G., Foster S.C. Correlation of metalloproteinase-2 and -9 with proinflammatory cytokines interleukin-1beta, interleukin-12 and the interleukin-1 receptor antagonist in patients with chronic uveitis. Curr Eye Res 2000, 20:211-214.
    • (2000) Curr Eye Res , vol.20 , pp. 211-214
    • El-Shabrawi, Y.G.1    Christen, W.G.2    Foster, S.C.3
  • 66
    • 0033927572 scopus 로고    scopus 로고
    • Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis
    • Agarwal R.K., Kang Y., Zambidis E., Scott D.W., Chan C.C., Caspi R.R. Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis. J Clin Invest 2000, 106:245-252.
    • (2000) J Clin Invest , vol.106 , pp. 245-252
    • Agarwal, R.K.1    Kang, Y.2    Zambidis, E.3    Scott, D.W.4    Chan, C.C.5    Caspi, R.R.6
  • 68
    • 0015895768 scopus 로고
    • Prevention of murine lupus nephritis by carrier-dependent induction of immunologic tolerance to denatured DNA
    • Borel Y., Lewis R.M., Stollar B.D. Prevention of murine lupus nephritis by carrier-dependent induction of immunologic tolerance to denatured DNA. Science 1973, 182:76-78.
    • (1973) Science , vol.182 , pp. 76-78
    • Borel, Y.1    Lewis, R.M.2    Stollar, B.D.3
  • 69
    • 0019227125 scopus 로고
    • Haptens bound to self IgG induce immunologic tolerance, while when coupled to syngeneic spleen cells they induce immune suppression
    • Borel Y. Haptens bound to self IgG induce immunologic tolerance, while when coupled to syngeneic spleen cells they induce immune suppression. Immunol Rev 1980, 50:71-104.
    • (1980) Immunol Rev , vol.50 , pp. 71-104
    • Borel, Y.1
  • 70
    • 51249124438 scopus 로고    scopus 로고
    • Tumor necrosis factor-α small interfering RNA decreases herpes simplex virus induced inflammation in a mouse model
    • Choi B., Hwang Y., Kwon H.J., Lee E.S., Park K.S., Bang D., et al. Tumor necrosis factor-α small interfering RNA decreases herpes simplex virus induced inflammation in a mouse model. J Dermatol Sci 2008, 52:87-97.
    • (2008) J Dermatol Sci , vol.52 , pp. 87-97
    • Choi, B.1    Hwang, Y.2    Kwon, H.J.3    Lee, E.S.4    Park, K.S.5    Bang, D.6
  • 71
    • 67349102674 scopus 로고    scopus 로고
    • Down regulation of inducible co-stimulator (ICOS) by intravitreal injection of small interfering RNA (siRNA) plasmid suppresses ongoing experimental autoimmune uveoretinitis in rats
    • Hou Y., Xing L., Fu S., Zhang X., Liu J., Liu H., et al. Down regulation of inducible co-stimulator (ICOS) by intravitreal injection of small interfering RNA (siRNA) plasmid suppresses ongoing experimental autoimmune uveoretinitis in rats. Graefes Arch Clin Exp Ophthalmol 2009, 247:755-765.
    • (2009) Graefes Arch Clin Exp Ophthalmol , vol.247 , pp. 755-765
    • Hou, Y.1    Xing, L.2    Fu, S.3    Zhang, X.4    Liu, J.5    Liu, H.6


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