메뉴 건너뛰기




Volumn 15, Issue 22, 2008, Pages 1478-1488

Lentiviral-vector-mediated expression of murine IL-1 receptor antagonist or IL-10 reduces the severity of endotoxin-induced uveitis

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA; ENDOTOXIN; FLUORESCEIN; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; LENTIVIRUS VECTOR;

EID: 55549121559     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2008.109     Document Type: Article
Times cited : (41)

References (55)
  • 1
    • 31644445580 scopus 로고    scopus 로고
    • Uveitis in the elderly: Epidemiological data from the national long-term care survey medicare cohort
    • Reeves SW, Sloan FA, Lee PP, Jaffe GJ. Uveitis in the elderly: epidemiological data from the national long-term care survey medicare cohort. Ophthalmology 2006, 113: 307
    • (2006) Ophthalmology , vol.113 , pp. 307
    • Reeves, S.W.1    Sloan, F.A.2    Lee, P.P.3    Jaffe, G.J.4
  • 2
    • 0037405484 scopus 로고    scopus 로고
    • Visual loss associated with pediatric uveitis in English primary and referral centers
    • Edelsten C, Reddy MA, Stanford MR, Graham EM. Visual loss associated with pediatric uveitis in English primary and referral centers. Am J Ophthalmol 2003; 135: 676-680.
    • (2003) Am J Ophthalmol , vol.135 , pp. 676-680
    • Edelsten, C.1    Reddy, M.A.2    Stanford, M.R.3    Graham, E.M.4
  • 3
    • 1442275270 scopus 로고    scopus 로고
    • Incidence and prevalence of uveitis in Northern California; the Northern California Epidemiology of Uveitis Study
    • Gritz DC, Wong IG. Incidence and prevalence of uveitis in Northern California; the Northern California Epidemiology of Uveitis Study. Ophthalmology 2004; 111: 491-500.
    • (2004) Ophthalmology , vol.111 , pp. 491-500
    • Gritz, D.C.1    Wong, I.G.2
  • 4
    • 34247252966 scopus 로고    scopus 로고
    • Nonsteroidal drugs for the treatment of noninfectious posterior and intermediate uveitis
    • Imrie FR, Dick AD. Nonsteroidal drugs for the treatment of noninfectious posterior and intermediate uveitis. Curr Opin Ophthalmol 2007; 18: 212-219.
    • (2007) Curr Opin Ophthalmol , vol.18 , pp. 212-219
    • Imrie, F.R.1    Dick, A.D.2
  • 5
    • 22644445751 scopus 로고    scopus 로고
    • Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental. autoimmune uveitis
    • Broderick CA, Smith AJ, Balaggan KS, Georgiadis A, Buch PK, Trittibach PC et al. Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental. autoimmune uveitis. Mol Ther 2005; 12: 369-373.
    • (2005) Mol Ther , vol.12 , pp. 369-373
    • Broderick, C.A.1    Smith, A.J.2    Balaggan, K.S.3    Georgiadis, A.4    Buch, P.K.5    Trittibach, P.C.6
  • 6
    • 0038576873 scopus 로고    scopus 로고
    • Neutralizing tumor necrosis factor-alpha activity suppresses activation of infiltrating macrophages in experimental autoimmune uveoretinitis
    • Robertson M, Liversidge J, Forrester JV, Dick AD. Neutralizing tumor necrosis factor-alpha activity suppresses activation of infiltrating macrophages in experimental autoimmune uveoretinitis. Invest Ophthalmol Vis Sci 2003; 44: 3034-3041.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 3034-3041
    • Robertson, M.1    Liversidge, J.2    Forrester, J.V.3    Dick, A.D.4
  • 7
    • 34147193118 scopus 로고    scopus 로고
    • Infliximab and etanercept in the treatment of chronic uveitis associated with refractory juvenile idiopathic arthritis
    • Tynjala P, Lindahl P, Honkanen V, Lahdenne P, Kotaniemi K. Infliximab and etanercept in the treatment of chronic uveitis associated with refractory juvenile idiopathic arthritis. Ann Rheum Dis 2007; 66: 548-550.
    • (2007) Ann Rheum Dis , vol.66 , pp. 548-550
    • Tynjala, P.1    Lindahl, P.2    Honkanen, V.3    Lahdenne, P.4    Kotaniemi, K.5
  • 8
    • 24944449409 scopus 로고    scopus 로고
    • Tetracycline-inducible viral interleukin-10 intraocular gene transfer, using adeno-associated virus in experimental autoinumme uveoretinitis
    • Smith JR, Verwaerde C, Rolling F, Naud MC, Delanoye A, Thillaye-Goldenberg B et al. Tetracycline-inducible viral interleukin-10 intraocular gene transfer, using adeno-associated virus in experimental autoinumme uveoretinitis. Hum Gene Ther 2005; 16: 1037-1046.
    • (2005) Hum Gene Ther , vol.16 , pp. 1037-1046
    • Smith, J.R.1    Verwaerde, C.2    Rolling, F.3    Naud, M.C.4    Delanoye, A.5    Thillaye-Goldenberg, B.6
  • 9
    • 0019304038 scopus 로고
    • Endotoxin-induced uveitis in rats as a model for human disease
    • Rosenbaum JT, McDevitt HO, Guss RB, Egbert PR. Endotoxin-induced uveitis in rats as a model for human disease. Nature 1980; 286: 611-613.
    • (1980) Nature , vol.286 , pp. 611-613
    • Rosenbaum, J.T.1    McDevitt, H.O.2    Guss, R.B.3    Egbert, P.R.4
  • 11
    • 0028174061 scopus 로고
    • Function and activation of NF-kappa B in the immune system
    • Baeuerle PA, Henkel T. Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 1994; 12: 141-179.
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 12
    • 0030271387 scopus 로고    scopus 로고
    • NF-kappa B: Ten years after
    • Baeuerle PA, Baltimore D. NF-kappa B: Ten years after. Cell 1996; 87: 13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 13
    • 0028097369 scopus 로고
    • Expression of multiple cytokines and IL-1RA in the uvea and retina during endotoxin-induced uveitis in the rat
    • de Vos AF, Klaren VN, Kijlstra A. Expression of multiple cytokines and IL-1RA in the uvea and retina during endotoxin-induced uveitis in the rat. Invest Ophthalmol Vis Sci 1994; 35: 3873-3883.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 3873-3883
    • de Vos, A.F.1    Klaren, V.N.2    Kijlstra, A.3
  • 15
    • 0034472026 scopus 로고    scopus 로고
    • Cytokine gene expression in different strains of mice with endotoxin-induced uveitis (EIU)
    • Shen DF, Buggage RR, Eng HC, Chan CC. Cytokine gene expression in different strains of mice with endotoxin-induced uveitis (EIU). Ocul Immunol Inflamm 2000; 8: 221-225.
    • (2000) Ocul Immunol Inflamm , vol.8 , pp. 221-225
    • Shen, D.F.1    Buggage, R.R.2    Eng, H.C.3    Chan, C.C.4
  • 17
    • 0029967110 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase in the eye from endotoxin-induced uveitis rats
    • Jacquemin E, De Kozak Y, Thillaye B, Courtois Y, Goureau O. Expression of inducible nitric oxide synthase in the eye from endotoxin-induced uveitis rats. Invest Ophthalmol Vis Sci 1996; 37: 1187-1196.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 1187-1196
    • Jacquemin, E.1    De Kozak, Y.2    Thillaye, B.3    Courtois, Y.4    Goureau, O.5
  • 18
    • 0030007891 scopus 로고    scopus 로고
    • Additive effect of nitric oxide and prostaglandin-E2 synthesis inhibitors in endotoxin-induced uveitis in the rabbit
    • Bellot JL, Palmero M, Garcia-Cabanes C, Espi R, Hariton C, Orts A. Additive effect of nitric oxide and prostaglandin-E2 synthesis inhibitors in endotoxin-induced uveitis in the rabbit. Inflamm Res 1996; 45: 203-208.
    • (1996) Inflamm Res , vol.45 , pp. 203-208
    • Bellot, J.L.1    Palmero, M.2    Garcia-Cabanes, C.3    Espi, R.4    Hariton, C.5    Orts, A.6
  • 19
    • 0036694645 scopus 로고    scopus 로고
    • The balance between IL-1 and IL-1Ra in disease
    • Arend WP. The balance between IL-1 and IL-1Ra in disease. Cytokine Growth Factor Rev 2002; 13: 323-340.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 323-340
    • Arend, W.P.1
  • 20
    • 0036888372 scopus 로고    scopus 로고
    • Cytokines: Promoters and dampeners of autoimmunity
    • Hill N, Sarvetnick N. Cytokines: Promoters and dampeners of autoimmunity. Curr Opin Immunol 2002; 14: 791-797.
    • (2002) Curr Opin Immunol , vol.14 , pp. 791-797
    • Hill, N.1    Sarvetnick, N.2
  • 21
    • 0033523019 scopus 로고    scopus 로고
    • Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action
    • Riley JK, Takeda K, Akira S, Schreiber RD. Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action. J Biol Chem 1999; 274: 16513-16521.
    • (1999) J Biol Chem , vol.274 , pp. 16513-16521
    • Riley, J.K.1    Takeda, K.2    Akira, S.3    Schreiber, R.D.4
  • 23
    • 0035182556 scopus 로고    scopus 로고
    • In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; efficient long-term transduction of corneal endothelium and retinal pigment epithelium
    • Bainbridge JW, Stephens C, Parsley K, Demaison C, Halfyard A, Thrasher AJ et al. In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; efficient long-term transduction of corneal endothelium and retinal pigment epithelium. Gene Therapy 2001; 8: 1665-1668.
    • (2001) Gene Therapy , vol.8 , pp. 1665-1668
    • Bainbridge, J.W.1    Stephens, C.2    Parsley, K.3    Demaison, C.4    Halfyard, A.5    Thrasher, A.J.6
  • 24
    • 0033981566 scopus 로고    scopus 로고
    • A defined window for efficient gene marking of severe combined immunodeficient-repopulating cells using a gibbon ape leukemia virus-pseudotyped retroviral vector
    • Demaison C, Brouns G, Blundell MP, Goldman JP, Levinsky RJ, Grez M et al. A defined window for efficient gene marking of severe combined immunodeficient-repopulating cells using a gibbon ape leukemia virus-pseudotyped retroviral vector. Hum Gene Ther 2000; 11: 91-100.
    • (2000) Hum Gene Ther , vol.11 , pp. 91-100
    • Demaison, C.1    Brouns, G.2    Blundell, M.P.3    Goldman, J.P.4    Levinsky, R.J.5    Grez, M.6
  • 25
    • 17644415316 scopus 로고    scopus 로고
    • Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy
    • Tschernutter M, Schlichtenbrede FC, Howe S, Balaggan KS, Munro PM, Bainbridge JW et al. Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy. Gene Therapy 2005; 12: 694-701.
    • (2005) Gene Therapy , vol.12 , pp. 694-701
    • Tschernutter, M.1    Schlichtenbrede, F.C.2    Howe, S.3    Balaggan, K.S.4    Munro, P.M.5    Bainbridge, J.W.6
  • 27
    • 0031581174 scopus 로고    scopus 로고
    • Promoter attenuation in gene therapy: Interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression
    • Qin L, Ding Y, Pahud DR, Chang E, Imperiale MJ, Bromberg JS. Promoter attenuation in gene therapy: Interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression. Hum Gene Ther 1997; 8: 2019-2029.
    • (1997) Hum Gene Ther , vol.8 , pp. 2019-2029
    • Qin, L.1    Ding, Y.2    Pahud, D.R.3    Chang, E.4    Imperiale, M.J.5    Bromberg, J.S.6
  • 28
    • 0025167803 scopus 로고
    • Interleukin 1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis
    • Cominelli F, Nast CC, Clark BD, Schindler R, Lierena R, Eysselein VE et al. Interleukin 1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis. J Clin Invest 1990; 86: 972-980.
    • (1990) J Clin Invest , vol.86 , pp. 972-980
    • Cominelli, F.1    Nast, C.C.2    Clark, B.D.3    Schindler, R.4    Lierena, R.5    Eysselein, V.E.6
  • 29
    • 0026697049 scopus 로고
    • Recombinant interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous interleukin-1 in rabbit immune colitis
    • Cominelli F, Nast CC, Duchini A, Lee M. Recombinant interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous interleukin-1 in rabbit immune colitis. Gastroenterology 1992; 103: 65-71.
    • (1992) Gastroenterology , vol.103 , pp. 65-71
    • Cominelli, F.1    Nast, C.C.2    Duchini, A.3    Lee, M.4
  • 30
    • 0025873675 scopus 로고
    • Evaluation of an interleukin-1 receptor antagonist in the rat acetic acid-induced colitis model
    • Thomas TK, Will PC, Srivastava A, Wilson CL, Harbison M, Little J et al. Evaluation of an interleukin-1 receptor antagonist in the rat acetic acid-induced colitis model. Agents Actions 1991; 34: 187-190.
    • (1991) Agents Actions , vol.34 , pp. 187-190
    • Thomas, T.K.1    Will, P.C.2    Srivastava, A.3    Wilson, C.L.4    Harbison, M.5    Little, J.6
  • 31
    • 0028327808 scopus 로고
    • Tissue interleukin 1 and interleukin-1 receptor antagonist expression in enterocolitis in resistant and susceptible rats
    • McCall RD, Haskill S, Zimmermann EM, Lund PK, Thompson RC, Sartor RB. Tissue interleukin 1 and interleukin-1 receptor antagonist expression in enterocolitis in resistant and susceptible rats. Gastroenterology 1994; 106: 960-972.
    • (1994) Gastroenterology , vol.106 , pp. 960-972
    • McCall, R.D.1    Haskill, S.2    Zimmermann, E.M.3    Lund, P.K.4    Thompson, R.C.5    Sartor, R.B.6
  • 32
    • 22844449524 scopus 로고    scopus 로고
    • Suppression of immune-mediated ocular inflammation in mice by interleukin 1 receptor antagonist administration
    • Lim WK, Fujimoto C, Ursea R, Mahesh SP, Silver P, Chan CC et al. Suppression of immune-mediated ocular inflammation in mice by interleukin 1 receptor antagonist administration. Arch Ophthalmol 2005; 123: 957-963.
    • (2005) Arch Ophthalmol , vol.123 , pp. 957-963
    • Lim, W.K.1    Fujimoto, C.2    Ursea, R.3    Mahesh, S.P.4    Silver, P.5    Chan, C.C.6
  • 33
    • 33846845020 scopus 로고    scopus 로고
    • Tailoring biological treatment: Anakinra treatment of posterior uveitis associated with the CINCA syndrome
    • Teoh SC, Sharma S, Hogan A, Lee R, Ramanan AV, Dick AD. Tailoring biological treatment: Anakinra treatment of posterior uveitis associated with the CINCA syndrome. Br J Ophthalmol 2007; 91: 263-264.
    • (2007) Br J Ophthalmol , vol.91 , pp. 263-264
    • Teoh, S.C.1    Sharma, S.2    Hogan, A.3    Lee, R.4    Ramanan, A.V.5    Dick, A.D.6
  • 35
    • 0032102995 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis
    • Apparailly F, Verwaerde C, Jacquet C, Auriault C, Sany J, Jorgensen C. Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis. J Immunol 1998; 160: 5213-5220.
    • (1998) J Immunol , vol.160 , pp. 5213-5220
    • Apparailly, F.1    Verwaerde, C.2    Jacquet, C.3    Auriault, C.4    Sany, J.5    Jorgensen, C.6
  • 36
    • 30544453442 scopus 로고    scopus 로고
    • Inhibition of experimental autoimmune anterior uveitis by adenovirus-mediated transfer of the interleukin-10 gene
    • Fang IM, Lin CP, Yang CH, Chiang BL, Yang CM, Chau LY et al. Inhibition of experimental autoimmune anterior uveitis by adenovirus-mediated transfer of the interleukin-10 gene. J Ocul Pharmacol Ther. 2005; 21: 420-428.
    • (2005) J Ocul Pharmacol Ther , vol.21 , pp. 420-428
    • Fang, I.M.1    Lin, C.P.2    Yang, C.H.3    Chiang, B.L.4    Yang, C.M.5    Chau, L.Y.6
  • 37
    • 0036406868 scopus 로고    scopus 로고
    • Inhibition of experimental autoimmune uveoretinitis by systemic and subconjunctival adenovirus-mediated transfer of the viral IL-10 gene
    • De Kozak Y, Thillaye-Goldenberg B, Naud MC, Da Costa AV, Auriault C, Verwaerde C. Inhibition of experimental autoimmune uveoretinitis by systemic and subconjunctival adenovirus-mediated transfer of the viral IL-10 gene. Clin Exp Immunol 2002; 130: 212-223.
    • (2002) Clin Exp Immunol , vol.130 , pp. 212-223
    • De Kozak, Y.1    Thillaye-Goldenberg, B.2    Naud, M.C.3    Da Costa, A.V.4    Auriault, C.5    Verwaerde, C.6
  • 39
    • 0034130299 scopus 로고    scopus 로고
    • Therapy and prevention of arthritis by recombinant adeno-associated virus vector with delivery of interleukin-1 receptor antagonist
    • Pan RY, Chen SL, Xiao X, Liu DW, Peng HJ, Tsao YP. Therapy and prevention of arthritis by recombinant adeno-associated virus vector with delivery of interleukin-1 receptor antagonist. Arthritis Rheum 2000; 43: 289-297.
    • (2000) Arthritis Rheum , vol.43 , pp. 289-297
    • Pan, R.Y.1    Chen, S.L.2    Xiao, X.3    Liu, D.W.4    Peng, H.J.5    Tsao, Y.P.6
  • 40
    • 0030031182 scopus 로고    scopus 로고
    • Pharmacokinetics and immunomodulatory properties of intravenously administered recombinant human interleukin-10 in healthy volunteers
    • Huhn RD, Radwanski E, O'Connell SM, Sturgill MG, Clarke L, Cody RP et al. Pharmacokinetics and immunomodulatory properties of intravenously administered recombinant human interleukin-10 in healthy volunteers. Blood 1996; 87: 699-705.
    • (1996) Blood , vol.87 , pp. 699-705
    • Huhn, R.D.1    Radwanski, E.2    O'Connell, S.M.3    Sturgill, M.G.4    Clarke, L.5    Cody, R.P.6
  • 41
    • 2342505985 scopus 로고    scopus 로고
    • A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer
    • Gouze JN, Gouze E, Palmer GD, Liew VS, Pascher A, Betz OB et al. A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer. Arthritis Res Ther 2003, 5: R301-R309.
    • (2003) Arthritis Res Ther , vol.5
    • Gouze, J.N.1    Gouze, E.2    Palmer, G.D.3    Liew, V.S.4    Pascher, A.5    Betz, O.B.6
  • 42
    • 0034122396 scopus 로고    scopus 로고
    • Interleukin 10 gene transfer prevents experimental colitis in rats
    • Barbara G, Xing Z, Hogaboam CM, Gauldie J, Collins SM. Interleukin 10 gene transfer prevents experimental colitis in rats. Gut 2000; 46: 344-349.
    • (2000) Gut , vol.46 , pp. 344-349
    • Barbara, G.1    Xing, Z.2    Hogaboam, C.M.3    Gauldie, J.4    Collins, S.M.5
  • 43
    • 0029795485 scopus 로고    scopus 로고
    • Administration of neutralizing antibody against rabbit IL-1 receptor antagonist exacerbates lipopolysaccharide-induced arthritis in rabbits
    • Fukumoto T, Matsukawa A, Ohkawara S, Takagi K, Yoshinaga, M. Administration of neutralizing antibody against rabbit IL-1 receptor antagonist exacerbates lipopolysaccharide-induced arthritis in rabbits. Inflamm Res 1996; 45: 479-485.
    • (1996) Inflamm Res , vol.45 , pp. 479-485
    • Fukumoto, T.1    Matsukawa, A.2    Ohkawara, S.3    Takagi, K.4    Yoshinaga, M.5
  • 44
    • 0042196164 scopus 로고    scopus 로고
    • Science review: Cell membrane expression (connectivity) regulates neutrophil delivery, function and clearance
    • Seely AJ, Pascual JL, Christou NV. Science review: Cell membrane expression (connectivity) regulates neutrophil delivery, function and clearance. Crit Care 2003; 7: 291-307.
    • (2003) Crit Care , vol.7 , pp. 291-307
    • Seely, A.J.1    Pascual, J.L.2    Christou, N.V.3
  • 45
    • 0029921163 scopus 로고    scopus 로고
    • Regulation of ICAM-1 expression by inflammatory cytokines in rat mesangial cells
    • Ikeda M, Ikeda U, Shimada. K, Minota S, Kano S. Regulation of ICAM-1 expression by inflammatory cytokines in rat mesangial cells. Cytokine 1996; 8: 109-114.
    • (1996) Cytokine , vol.8 , pp. 109-114
    • Ikeda, M.1    Ikeda, U.2    Shimada, K.3    Minota, S.4    Kano, S.5
  • 46
    • 0036398446 scopus 로고    scopus 로고
    • The IL-1 family and inflammatory diseases
    • Dinarello CA. The IL-1 family and inflammatory diseases. Clin Exp Rheumatol 2002; 20: S1-13.
    • (2002) Clin Exp Rheumatol , vol.20
    • Dinarello, C.A.1
  • 47
    • 0034787987 scopus 로고    scopus 로고
    • Inhibition of leukocyte sticking and infiltration, but not rolling, by antibodies to ICAM-1. and LFA-1 in munne endotoxin-induced uveitis
    • Becker MD, Garman K, Whitcup SM, Planck SR, Rosenbaum JT. Inhibition of leukocyte sticking and infiltration, but not rolling, by antibodies to ICAM-1. and LFA-1 in munne endotoxin-induced uveitis. Invest Ophthalmol Vis Sci 2001; 42: 2563-2566.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2563-2566
    • Becker, M.D.1    Garman, K.2    Whitcup, S.M.3    Planck, S.R.4    Rosenbaum, J.T.5
  • 49
    • 0037406962 scopus 로고    scopus 로고
    • Contribution of TNF-alpha to leukocyte adhesion, vascular leakage, and apoptotic cell death in endotoxin-induced uveitis in vivo
    • Koizumi K, Poulaki V, Doehmen S, Welsandt G, Radetzky S, Lappas A et al. Contribution of TNF-alpha to leukocyte adhesion, vascular leakage, and apoptotic cell death in endotoxin-induced uveitis in vivo. Invest Ophthalmol Vis Sci 2003; 44: 2184-2191.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 2184-2191
    • Koizumi, K.1    Poulaki, V.2    Doehmen, S.3    Welsandt, G.4    Radetzky, S.5    Lappas, A.6
  • 50
    • 0033525435 scopus 로고    scopus 로고
    • Expression of intercellular adhesion molecule 1 (ICAM-1) is reduced in permanent focal cerebral ischemic mouse brain using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist
    • Yang GY, Mao Y, Zhou LF, Gong C, Ge HL, Betz AL. Expression of intercellular adhesion molecule 1 (ICAM-1) is reduced in permanent focal cerebral ischemic mouse brain using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist. Brain Res Mol Brain Res 1999; 65: 143-150.
    • (1999) Brain Res Mol Brain Res , vol.65 , pp. 143-150
    • Yang, G.Y.1    Mao, Y.2    Zhou, L.F.3    Gong, C.4    Ge, H.L.5    Betz, A.L.6
  • 51
    • 0036180817 scopus 로고    scopus 로고
    • Kinetics of transgene expression in mouse retina following sub-retinal injection of recombinant adeno-associated virus
    • Sarra GM, Stephens C, Schlichtenbrede FC, Bainbridge JW, Thrasher AJ, Luthert PJ et al. Kinetics of transgene expression in mouse retina following sub-retinal injection of recombinant adeno-associated virus. Vision Res 2002; 42: 541-549.
    • (2002) Vision Res , vol.42 , pp. 541-549
    • Sarra, G.M.1    Stephens, C.2    Schlichtenbrede, F.C.3    Bainbridge, J.W.4    Thrasher, A.J.5    Luthert, P.J.6
  • 52
    • 0036083592 scopus 로고    scopus 로고
    • Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy
    • Lai YK, Shen WY, Brankov M, Lai CM, Constable IJ, Rakoczy PE. Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy. Gene Therapy 2002; 9: 804-813.
    • (2002) Gene Therapy , vol.9 , pp. 804-813
    • Lai, Y.K.1    Shen, W.Y.2    Brankov, M.3    Lai, C.M.4    Constable, I.J.5    Rakoczy, P.E.6
  • 53
    • 20844463069 scopus 로고    scopus 로고
    • Stability of Ientiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses
    • Abordo-Adesida E, Follenzi A, Barcia C, Sciascia S, Castro MG, Naldini L et al. Stability of Ientiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses. Hum Gene Ther 2005; 16: 741-751.
    • (2005) Hum Gene Ther , vol.16 , pp. 741-751
    • Abordo-Adesida, E.1    Follenzi, A.2    Barcia, C.3    Sciascia, S.4    Castro, M.G.5    Naldini, L.6
  • 54
    • 0033035831 scopus 로고    scopus 로고
    • Characterization of phenotype and cytokine profiles of T cell lines derived from vitreous humour in ocular inflammation in man
    • Muhaya M, Calder VL, Towler HM, Jolly G, McLauchlan M, Lightman S. Characterization of phenotype and cytokine profiles of T cell lines derived from vitreous humour in ocular inflammation in man. Clin Exp Immunol 1999; 116: 410-414.
    • (1999) Clin Exp Immunol , vol.116 , pp. 410-414
    • Muhaya, M.1    Calder, V.L.2    Towler, H.M.3    Jolly, G.4    McLauchlan, M.5    Lightman, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.