Intracranial tumor response to respiratory challenges at 3.0 T: Impact of different methods to quantify changes in the MR relaxation rate R2*

Journal of Magnetic Resonance Imaging

Volumn 32, Issue 1, 2010, Pages 17-23

  Müller, Andreas ^a   Remmele, Stefanie ^b   Wenningmann, Ingobert ^a   Clusmann, Hans ^a   Träber, Frank ^a   Flacke, Sebastian ^a,c   König, Roy ^a   Gieseke, Jürgen ^a,d   Willinek, Winfried A ^a   Schild, Hans H ^a   Mürtz, Petra ^a  

^a UNIVERSITY OF BONN   (Germany)

^b PHILIPS RESEARCH LABORATORIES   (Germany)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d PHILIPS HEALTHCARE   (United States)

Author keywords

3.0 T; BOLD; Intracranial tumors; Oxygenation; Quantification methods; Vasoreactivity; R2*

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD OXYGENATION; BREATHING MECHANICS; CLINICAL ARTICLE; FEMALE; HUMAN; INTRACRANIAL TUMOR; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; BRAIN; BRAIN TUMOR; BREATHING; COMPARATIVE STUDY; ECHO PLANAR IMAGING; GLIOBLASTOMA; HYPERCAPNIA; HYPEROXIA; IMAGE PROCESSING; MENINGIOMA; METABOLISM; MIDDLE AGED; NONHODGKIN LYMPHOMA; PATHOLOGY; PROCEDURES; SECONDARY; SENSITIVITY AND SPECIFICITY;

CARBOGEN; CARBON DIOXIDE; OXYGEN;

ADULT; AGED; BRAIN; BRAIN NEOPLASMS; CARBON DIOXIDE; ECHO-PLANAR IMAGING; FEMALE; GLIOBLASTOMA; HUMANS; HYPERCAPNIA; HYPEROXIA; IMAGE PROCESSING, COMPUTER-ASSISTED; LYMPHOMA, NON-HODGKIN; MAGNETIC RESONANCE IMAGING; MALE; MENINGIOMA; MIDDLE AGED; OXYGEN; RESPIRATION; SENSITIVITY AND SPECIFICITY;

EID: 77954138587     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.22205     Document Type: Article

References (43)

1. Ogawa S, Lee TM, Kay AR, Tank DW. Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci U S A 1990;87:9868-9872. (Pubitemid 120016545)
2. Baudelet C, Gallez B. Current issues in the utility of blood oxygen level dependent MRI for the assessment of modulations in tumor oxygenation. Curr Med Imaging Rev 2005;1:229-243.
3. Punwani S, Ordidge RJ, Cooper CE, Amess P, Clemence M. MRI measurements of cerebral deoxyhaemoglobin concentration [dHb] - correlation with near infrared spectroscopy (NIRS). NMR Biomed 1998;11:281-289.
4. Neeman M, Dafni H. Structural, functional, and molecular MR imaging of the microvasculature. Annu Rev Biomed Eng 2003;5:29-56. (Pubitemid 40125307)
5. Baudelet C, Gallez B. How does blood oxygen level-dependent (BOLD) contrast correlate with oxygen partial pressure (pO2) inside tumors? Magn Reson Med 2002;48:980-986.
6. Yetkin FZ, Mendelsohn D. Hypoxia imaging in brain tumors. Neuroimaging Clin N Am 2002;12:537-552.
7. Howe FA, Robinson SP, McIntyre DJ, Stubbs M, Griffiths JR. Issues in flow and oxygenation dependent contrast (FLOOD) imaging of tumours. NMR Biomed 2001;14:497-506. (Pubitemid 33150238)
8. Peebles K, Celi L, McGrattan K, Murrell C, Thomas K, Ainslie PN. Human cerebrovascular and ventilatory CO2 reactivity to endtidal, arterial and internal jugular vein PCO2. J Physiol 2007;584:347-357. (Pubitemid 47500559)
9. Ziyeh S, Rick J, Reinhard M, Hetzel A, Mader I, Speck O. Blood oxygen level-dependent MRI of cerebral CO2 reactivity in severe carotid stenosis and occlusion. Stroke 2005;36:751-756.
10. van der Zande FH, Hofman PA, Backes WH. Mapping hypercapnia-induced cerebrovascular reactivity using BOLD MRI. Neuroradiology 2005;47:114-120.
11. Kastrup A, Kruger G, Neumann-Haefelin T, Moseley ME. Assessment of cerebrovascular reactivity with functional magnetic resonance imaging: comparison of CO(2) and breath holding. Magn Reson Imaging 2001;19:13-20.
12. Vesely A, Sasano H, Volgyesi G, et al. MRI mapping of cerebrovascular reactivity using square wave changes in end-tidal PCO2. Magn Reson Med 2001;45:1011-1013.
13. Rostrup E, Law I, Blinkenberg M, et al. Regional differences in the CBF and BOLD responses to hypercapnia: a combined PET and fMRI study. NeuroImage 2000;11:87-97. (Pubitemid 30141447)
14. Baudelet C, Cron GO, Gallez B. Determination of the maturity and functionality of tumor vasculature by MRI: correlation between BOLD-MRI and DCE-MRI using P792 in experimental fibrosarcoma tumors. Magn Reson Med 2006;56:1041-1049. (Pubitemid 44691346)
15. Neeman M, Dafni H, Bukhari O, Braun RD, Dewhirst MW. In vivo BOLD contrast MRI mapping of subcutaneous vascular function and maturation: validation by intravital microscopy. Magn Reson Med 2001;45:887-898.
16. Rodrigues LM, Howe FA, Griffiths JR, Robinson SP. Tumor R2* is a prognostic indicator of acute radiotherapeutic response in rodent tumors. J Magn Reson Imaging 2004;19:482-488.
17. Abramovitch R, Dafni H, Smouha E, Benjamin LE, Neeman M. In vivo prediction of vascular susceptibility to vascular susceptibility endothelial growth factor withdrawal: magnetic resonance imaging of C6 rat glioma in nude mice. Cancer Res 1999;59:5012-5016.
18. Robinson SP, Collingridge DR, Howe FA, Rodrigues LM, Chaplin DJ, Griffiths JR. Tumour response to hypercapnia and hyperoxia monitored by FLOOD magnetic resonance imaging. NMR Biomed 1999;12:98-106.
19. Kuperman VY, River JN, Lewis MZ, Lubich LM, Karczmar GS. Changes in T2*-weighted images during hyperoxia differentiate tumors from normal tissue. Magn Reson Med 1995;33:318-325.
20. Rauscher A, Sedlacik J, Fitzek C, et al. High resolution susceptibility weighted MR-imaging of brain tumors during the application of a gaseous agent. Rofo 2005;177:1065-1069.
21. Rijpkema M, Schuuring J, Bernsen PL, et al. BOLD MRI response to hypercapnic hyperoxia in patients with meningiomas: correlation with Gadolinium-DTPA uptake rate. Magn Reson Imaging 2004;22:761-767. (Pubitemid 38962312)
22. Rijpkema M, Kaanders JH, Joosten FB, van der Kogel AJ, Heerschap A. Effects of breathing a hyperoxic hypercapnic gas mixture on blood oxygenation and vascularity of head-and-neck tumors as measured by magnetic resonance imaging. Int J Radiat Oncol Biol Phys 2002;53:1185-1191. (Pubitemid 34787854)
23. Taylor NJ, Baddeley H, Goodchild KA, et al. BOLD MRI of human tumor oxygenation during carbogen breathing. J Magn Reson Imaging 2001;14:156-163.
24. Griffiths JR, Taylor NJ, Howe FA, et al. The response of human tumors to carbogen breathing, monitored by gradient-recalled echo magnetic resonance imaging. Int J Radiat Oncol Biol Phys 1997;39:697-701.
25. Prisman E, Slessarev M, Azami T, Nayot D, Milosevic M, Fisher J. Modified oxygen mask to induce target levels of hyperoxia and hypercarbia during radiotherapy: a more effective alternative to carbogen. Int J Radiat Biol 2007;83:457-462. (Pubitemid 46854840)
26. Howe FA, Robinson SP, Rodrigues LM, Griffiths JR. Flow and oxygenation dependent (FLOOD) contrast MR imaging to monitor the response of rat tumors to carbogen breathing. Magn Reson Imaging 1999;17:1307-1318.
27. Ashkanian M, Borghammer P, Gjedde A, Ïstergaard L, Vafaee M. Improvement of brain tissue oxygenation by inhalation of carbogen. Neuroscience 2008;156:932-938.
28. Reichenbach JR, Venkatesan R, Yablonskiy DA, Thompson MR, Lai S, Haacke EM. Theory and application of static field inhomogeneity effects in gradient-echo imaging. J Magn Reson Imaging 1997;7:266-279. (Pubitemid 28356957)
29. Yablonskiy DA, Haacke EM. An MRI method for measuring T2 in the presence of static and RF magnetic field inhomogeneities. Magn Reson Med 1997;37:872-876.
30. Dahnke H, Persigehl T, Wall A, Heindel WL, Bremer C, Schaeffter T. Optimal calculation of relaxation rate changes for quantitative MRI applied to tumor blood volume determination. In: Proc 13th Annual Meeting ISMRM, Miami; 2005 (abstract 2107).
31. Winkelmann S, Dahnke H, Flacke S, et al. Measuring the effect of hyperoxia and hypercapnia on R2* and the balanced SSFP signal at 3T. In: Proc 16th Annual Meeting ISMRM, Toronto; 2008 (abstract 858).
32. Netsch T, Rösch P, van Muiswinkel A, Weese J. Towards real-time multi-modality 3D medical image registration. In: Proc ICCV; 2001 (abstract 501).
33. Hagberg GE, Indovina I, Sanes JN, Posse S. Real-time quantification of T(2)(*) changes using multiecho planar imaging and numerical methods. Magn Reson Med 2002;48:877-882.
34. Dahnke H, Schaeffter T. Limits of detection of SPIO at 3.0 T using T2 relaxometry. Magn Reson Med 2005;53:1202-1206. (Pubitemid 40627800)
35. Persigehl T, Wall A, Kellert J, Heindel W, Bremer C, Dahnke H. Determination of tumor vascular volume fraction by an optimized method for DR2* calculation. In: Proc 93rd Scientific Assembly and Annual Meeting RSNA, Chicago; 2007 (abstract SSM05-05).
36. Winkelmann S, Senegas J, Ring J, Persigehl T, Bremer C, Dahnke H. Rosbust simultaneous DR2 and DR2* estimation for vessel size imaging. In: Proc 16th Annual Meeting ISMRM, Toronto; 2008 (abstract 236).
37. Müller A, Remmele S, Wenningmann I, et al. MR signal response to hyperoxic and hypercapnic respiratory challenges in the brain at 3 T. In: Proc 7th International Symposium on Highfield MR in Clinical Applications, Bonn; 2009 (abstract 84).
38. Zhao D, Jiang L, Hahn EW, Mason RP. Comparison of 1H blood oxygen level-dependent (BOLD) and 19F MRI to investigate tumor oxygenation. Magn Reson Med 2009;62:357-364.
39. Gilad AA, Israely T, Dafni H, Meir G, Cohen B, Neeman M. Functional and molecular mapping of uncoupling between vascular permeability and loss of vascular maturation in ovarian carcinoma xenografts: the role of stroma cells in tumor angiogenesis. Int J Cancer 2005;117:202-211. (Pubitemid 41377439)
40. Packard SD, Mandeville JB, Ichikawa T, et al. Functional response of tumor vasculature to PaCO2: determination of total and microvascular blood volume by MRI. Neoplasia 2003;5:330-338.
41. Robinson SP, Rijken PF, Howe FA, et al. Tumor vascular architecture and function evaluated by non-invasive susceptibility MRI methods and immunohistochemistry. J Magn Reson Imaging 2003;17:445-454.
42. Hsu YY, Chang CN, Jung SM, et al. Blood oxygenation level-dependent MRI of cerebral gliomas during breath holding. J Magn Reson Imaging 2004;19:160-167.
43. Boxerman JL, Hamberg LM, Rosen BR, Weisskoff RM. MR contrast due to intravascular magnetic susceptibility perturbations. Magn Reson Med 1995;34:555-566.