메뉴 건너뛰기




Volumn 18, Issue 4, 2010, Pages 338-343

Predicting malignant potential of gastrointestinal stromal tumors: Role of p16 and E2F1 expression

Author keywords

E2F1; gastrointestinal stromal tumor; immunohistochemistry; Ki 67; p16

Indexed keywords

KI 67 ANTIGEN; PROTEIN P16; TRANSCRIPTION FACTOR E2F1;

EID: 77954110448     PISSN: 15412016     EISSN: 15334058     Source Type: Journal    
DOI: 10.1097/PAI.0b013e3181d245c0     Document Type: Article
Times cited : (4)

References (30)
  • 2
    • 12144288616 scopus 로고    scopus 로고
    • C-kit and PDGFRA mutations in extragastrointestinal stromal tumor (gastrointestinal stromal tumor of the soft tissue)
    • Yamamoto H, Oda Y, Kawaguchi K, et al. c-kit and PDGFRA mutations in extragastrointestinal stromal tumor (gastrointestinal stromal tumor of the soft tissue). Am J Surg Pathol. 2004;28: 479-488.
    • (2004) Am J Surg Pathol , vol.28 , pp. 479-488
    • Yamamoto, H.1    Oda, Y.2    Kawaguchi, K.3
  • 3
    • 23444443877 scopus 로고    scopus 로고
    • Prognostic significance of expression of cell-cycle regulatory proteins in gastrointestinal stromal tumor and the relevance of the risk grade
    • Nakamura N, Yamamoto H, Yao T, et al. Prognostic significance of expression of cell-cycle regulatory proteins in gastrointestinal stromal tumor and the relevance of the risk grade. Hum Pathol. 2005;36:828-837.
    • (2005) Hum Pathol , vol.36 , pp. 828-837
    • Nakamura, N.1    Yamamoto, H.2    Yao, T.3
  • 4
    • 4243733832 scopus 로고    scopus 로고
    • Molecular biology of sarcomas
    • De Vita VT, Helman S, Rosenberg SA, eds. 5th ed. Philadelphia: JB Lippincott Company
    • Cordon-Cardo C. Molecular biology of sarcomas. In: De Vita VT, Helman S, Rosenberg SA, eds. Principles and Practice of Oncology. 5th ed. Philadelphia: JB Lippincott Company; 1997:1731-1738.
    • (1997) Principles and Practice of Oncology , pp. 1731-1738
    • Cordon-Cardo, C.1
  • 5
    • 19944427609 scopus 로고    scopus 로고
    • Loss of p16 protein defines high risk patients with gastrointestinal stromal tumors: A tissue microarray study
    • Schneider SR, Boltze C, Lasota J, et al. Loss of p16 protein defines high risk patients with gastrointestinal stromal tumors: a tissue microarray study. Clin Cancer Res. 2005;11:638-645.
    • (2005) Clin Cancer Res , vol.11 , pp. 638-645
    • Schneider, S.R.1    Boltze, C.2    Lasota, J.3
  • 6
    • 8144222050 scopus 로고    scopus 로고
    • Loss of heterozygosity of chromosome 9p and loss of p 16INK4A expression are associated with malignant gastrointestinal stromal tumors
    • Sabah M, Cummins R, Leader M, et al. Loss of heterozygosity of chromosome 9p and loss of p 16INK4A expression are associated with malignant gastrointestinal stromal tumors. Mod Pathol. 2004;17:1364-1371.
    • (2004) Mod Pathol , vol.17 , pp. 1364-1371
    • Sabah, M.1    Cummins, R.2    Leader, M.3
  • 7
    • 33746033715 scopus 로고    scopus 로고
    • Pattern of expression of gene linked to epigenetic silencing in human breast cancer
    • Munot K, Bell SM, Lane S, et al. Pattern of expression of gene linked to epigenetic silencing in human breast cancer. Hum Pathol. 2006;37:989-999.
    • (2006) Hum Pathol , vol.37 , pp. 989-999
    • Munot, K.1    Bell, S.M.2    Lane, S.3
  • 8
    • 33644939223 scopus 로고    scopus 로고
    • McCluggage WG. p16 expression in the female genital tract and its value in diagnosis
    • O'Neill CJ, McCluggage WG. p16 expression in the female genital tract and its value in diagnosis. Adv Anat Pathol. 2006;13:8-15.
    • (2006) Adv Anat Pathol , vol.13 , pp. 8-15
    • O'Neill, C.J.1
  • 9
    • 37549051775 scopus 로고    scopus 로고
    • Diagnostic and prognostic markers for gastrointestinal stromal tumors in Norway
    • Steigen SE, Bjerkehagen B, Haugland HK, et al. Diagnostic and prognostic markers for gastrointestinal stromal tumors in Norway. Modern Pathol. 2008;21:46-53.
    • (2008) Modern Pathol , vol.21 , pp. 46-53
    • Steigen, S.E.1    Bjerkehagen, B.2    Haugland, H.K.3
  • 10
    • 33745469852 scopus 로고    scopus 로고
    • Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: Markers with potential prognostic implications
    • Sabah M, Cummins R, Leader M, et al. Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: markers with potential prognostic implications. Hum Pathol. 2006;37: 648-655.
    • (2006) Hum Pathol , vol.37 , pp. 648-655
    • Sabah, M.1    Cummins, R.2    Leader, M.3
  • 11
    • 0033989829 scopus 로고    scopus 로고
    • Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14ARF tumor supressor
    • Dimri GP, Itahana K, Acosta M, et al. Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14ARF tumor supressor. Mol Cell Biol. 2000;20:273-285.
    • (2000) Mol Cell Biol , vol.20 , pp. 273-285
    • Dimri, G.P.1    Itahana, K.2    Acosta, M.3
  • 12
    • 0028361374 scopus 로고
    • Regulation of two E2F related genes in presenescent and senescent human fibroblasts
    • Dimri GP, Hara EE, Campisi J, et al. Regulation of two E2F related genes in presenescent and senescent human fibroblasts. J Biol Chem. 1994;269:16180-16186.
    • (1994) J Biol Chem , vol.269 , pp. 16180-16186
    • Dimri, G.P.1    Hara, E.E.2    Campisi, J.3
  • 13
    • 0036773376 scopus 로고    scopus 로고
    • Transcription factor E2F1 acts as a growth promoting factor and is associated with adverse prognosis in non small cell carcinomas
    • Gorgoulis VG, Zacharatos P, Mariatos G, et al. Transcription factor E2F1 acts as a growth promoting factor and is associated with adverse prognosis in non small cell carcinomas. J Pathol. 2002;198:142-156.
    • (2002) J Pathol , vol.198 , pp. 142-156
    • Gorgoulis, V.G.1    Zacharatos, P.2    Mariatos, G.3
  • 14
    • 25144520884 scopus 로고    scopus 로고
    • Prognostic role of E2F1 and members of the CDKN2A network in gastrointestinal stromal tumors
    • Haller F, Gunawan B, Heydebreck AV, et al. Prognostic role of E2F1 and members of the CDKN2A network in gastrointestinal stromal tumors. Clin Cancer Res. 2005;11:6589-6597.
    • (2005) Clin Cancer Res , vol.11 , pp. 6589-6597
    • Haller, F.1    Gunawan, B.2    Heydebreck, A.V.3
  • 16
    • 10744233692 scopus 로고    scopus 로고
    • Prognostic indicators for gastrointestinal stromal tumors: A clinicopathological and immunohistochemial study of 108 resected cases of the stomach
    • Wong NACS, Young R, Malcomson RDG, et al. Prognostic indicators for gastrointestinal stromal tumors: a clinicopathological and immunohistochemial study of 108 resected cases of the stomach. Histopathology. 2003;43:118-126.
    • (2003) Histopathology , vol.43 , pp. 118-126
    • Nacs, W.1    Young, R.2    Rdg, M.3
  • 17
    • 0033868759 scopus 로고    scopus 로고
    • Prognostic factors in malignant gastrointestinal stromal tumors
    • Muro-cacho CA, Cantor AB, Morgan M. Prognostic factors in malignant gastrointestinal stromal tumors. Ann Clin Lab Sci. 2000;30:239-247.
    • (2000) Ann Clin Lab Sci , vol.30 , pp. 239-247
    • Muro-Cacho, C.A.1    Cantor, A.B.2    Morgan, M.3
  • 18
    • 0034049784 scopus 로고    scopus 로고
    • Predicting metastatic risk of gastrointestinal stromal tumors: Role of cell proliferation and cell cycle regulatory proteins
    • Panizo-Santos A, Sola I, Vega F, et al. Predicting metastatic risk of gastrointestinal stromal tumors: role of cell proliferation and cell cycle regulatory proteins. Int J Surg Pathol. 2000;8:133-144.
    • (2000) Int J Surg Pathol , vol.8 , pp. 133-144
    • Panizo-Santos, A.1    Sola, I.2    Vega, F.3
  • 19
    • 34948892047 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: Usefulness of immunohistochemistry, flow cytometry and fluorescence in situ hybridization
    • Fontana MG, Rossi E, Bassotti G, et al. Gastrointestinal stromal tumors: usefulness of immunohistochemistry, flow cytometry and fluorescence in situ hybridization. J Gastroenterol Hepatol. 2007;22:1754-1759.
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 1754-1759
    • Fontana, M.G.1    Rossi, E.2    Bassotti, G.3
  • 20
    • 33845717325 scopus 로고    scopus 로고
    • Immunohistochemical expression of p16INK4A Ki-67 and Mcm2 proteins in gastrointestinal stromal tumors: Prognostic implications and correlations with risk stratification of NIH consensus criteria
    • Huang HY, Huang WW, Lin CN, et al. Immunohistochemical expression of p16INK4A, Ki-67, and Mcm2 proteins in gastrointestinal stromal tumors: prognostic implications and correlations with risk stratification of NIH consensus criteria. Annals Surgical Oncol. 2006;13:1633-1644.
    • (2006) Annals Surgical Oncol , vol.13 , pp. 1633-1644
    • Huang, H.Y.1    Huang, W.W.2    Lin, C.N.3
  • 21
    • 34748818101 scopus 로고    scopus 로고
    • Prediction of aggressiveness of gastrointestinal stromal tumors based on immunostaining with bcl-2 KI?-67 and p53
    • Meara RS, Cangiarella J, Simsir A, et al. Prediction of aggressiveness of gastrointestinal stromal tumors based on immunostaining with bcl-2, KI?-67 and p53. Cytopathology. 2007;18:283-289.
    • (2007) Cytopathology , vol.18 , pp. 283-289
    • Meara, R.S.1    Cangiarella, J.2    Simsir, A.3
  • 22
    • 0029587551 scopus 로고
    • Alternative reading frames of the INK4a tumor supressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle DE, Zindy F, Ashmun RA, et al. Alternative reading frames of the INK4a tumor supressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell. 1995;83:993-1000.
    • (1995) Cell , vol.83 , pp. 993-1000
    • De, Q.1    Zindy, F.2    Ashmun, R.A.3
  • 23
    • 0035487104 scopus 로고    scopus 로고
    • The INK4a/ARF network in tumor supression
    • Sherr CJ. The INK4a/ARF network in tumor supression. Nat Rev Mol Cell Biol. 2001;2:731-737.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 731-737
    • Sherr, C.J.1
  • 24
    • 0034660868 scopus 로고    scopus 로고
    • DNA sequence copy number changes in gastrointestinal stromal tumors: Tumor progression and prognostic significance
    • El-Rifai W, Sarlomo-Rikala M, Anderson LC, et al. DNA sequence copy number changes in gastrointestinal stromal tumors: tumor progression and prognostic significance. Cancer Res. 2000;60:3899-3903.
    • (2000) Cancer Res , vol.60 , pp. 3899-3903
    • El-Rifai, W.1    Sarlomo-Rikala, M.2    Anderson, L.C.3
  • 25
    • 0038135029 scopus 로고    scopus 로고
    • High prognostic value of p16INK4 alterations in gastrointestinal stromal tumors
    • Schneider-Stock R, Boltze C, Lasota J, et al. High prognostic value of p16INK4 alterations in gastrointestinal stromal tumors. J Clin Oncol. 2003;21:1688-1697.
    • (2003) J Clin Oncol , vol.21 , pp. 1688-1697
    • Schneider-Stock, R.1    Boltze, C.2    Lasota, J.3
  • 26
    • 0031886093 scopus 로고    scopus 로고
    • Regulation of cell proliferation by E2F transcription factors
    • Helin K. Regulation of cell proliferation by E2F transcription factors. Curr Opin Genet Dev. 1997;8:28-35.
    • (1997) Curr Opin Genet Dev , vol.8 , pp. 28-35
    • Helin, K.1
  • 27
    • 0031815596 scopus 로고    scopus 로고
    • Toward an understanding of the functional complexity of the E2F and retinoblastoma families
    • Nevins JR. Toward an understanding of the functional complexity of the E2F and retinoblastoma families. Nat Genet. 1998;9: 585-593.
    • (1998) Nat Genet , vol.9 , pp. 585-593
    • Nevins, J.R.1
  • 28
    • 0034949169 scopus 로고    scopus 로고
    • Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
    • Ishida S, Huang E, Zuzan H, et al. Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol Cell Biol. 2001;21:4684-4699.
    • (2001) Mol Cell Biol , vol.21 , pp. 4684-4699
    • Ishida, S.1    Huang, E.2    Zuzan, H.3
  • 29
    • 0030053130 scopus 로고    scopus 로고
    • Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A mediated growth supression
    • Lukas J, Petersen BO, Holm K, et al. Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A mediated growth supression. Mol Cell Biol. 1996; 16:1047-1057.
    • (1996) Mol Cell Biol , vol.16 , pp. 1047-1057
    • Lukas, J.1    Petersen, B.O.2    Holm, K.3
  • 30
    • 0035936113 scopus 로고    scopus 로고
    • The E2F1-3 transcription factors are essential for cellular proliferation
    • Wu L, Timmers C, Maiti B, et al. The E2F1-3 transcription factors are essential for cellular proliferation. Nature. 2001;414:457-462.
    • (2001) Nature , vol.414 , pp. 457-462
    • Wu, L.1    Timmers, C.2    Maiti, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.