Therapeutic effect of a novel anti-parkinsonian agent zonisamide against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)neurotoxicity in mice

Metabolic Brain Disease

Volumn 25, Issue 2, 2010, Pages 135-143

  Yokoyama, Hironori ^a   Yano, Ryohei ^a   Kuroiwa, Hayato ^a   Tsukada, Tatsuya ^a   Uchida, Hiroto ^a   Kato, Hiroyuki ^b   Kasahara, Jiro ^a   Araki, Tsutomu ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

Behavioral test; Immunohistochemistry; Mice; MPTP; Parkinson's disease; Western blot analysis; Zonisamide

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; TYROSINE 3 MONOOXYGENASE; ZONISAMIDE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; DRUG EFFECT; FUNCTIONAL STATUS; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; MOTOR DYSFUNCTION; MOUSE; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PROTEIN DEPLETION; SUBSTANTIA NIGRA; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; ANTIPARKINSON AGENTS; DISEASE MODELS, ANIMAL; DOPAMINE; ISOXAZOLES; MALE; MICE; MICE, INBRED C57BL; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; PARKINSONIAN DISORDERS; SUBSTANTIA NIGRA; TREATMENT OUTCOME;

MUS; PARKINSONIA;

EID: 77954089281     PISSN: 08857490     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11011-010-9191-0     Document Type: Article

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