MEF2C silencing attenuates load-induced left ventricular hypertrophy by modulating mTOR/S6K pathway in mice

PLoS ONE

Volumn 4, Issue 12, 2009, Pages

  Pereira, Ana Helena M ^a   Clemente, Carolina F M Z ^a   Cardoso, Alisson C ^a   Theizen, Thais H ^a   Rocco, Silvana A ^a   Judice, Carla C ^a   Guido, Maria Carolina ^a   Pascoal, Vinícius D B ^a   Lopes Cendes, Iscia ^a   Souza, Joséroberto M ^a   Franchini, Kleber G ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ATRIAL NATRIURETIC FACTOR; MAMMALIAN TARGET OF RAPAMYCIN; MITOCHONDRIAL DNA; MYOCYTE ENHANCER FACTOR 2; MYOCYTE ENHANCER FACTOR 2C; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; S6 KINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENERGY METABOLISM; GENE SILENCING; HEART FAILURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE FIBROSIS; HEART MUSCLE METABOLISM; MECHANICAL STRESS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE;

ANIMALS; CELLS, CULTURED; DNA, MITOCHONDRIAL; GENE SILENCING; HEMODYNAMICS; HYPERTROPHY, LEFT VENTRICULAR; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MYOCARDIUM; MYOCYTES, CARDIAC; MYOGENIC REGULATORY FACTORS; PROTEIN-SERINE-THREONINE KINASES; RATS; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; VENTRICULAR PRESSURE;

MUS;

EID: 77954050386     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008472     Document Type: Article

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