-
1
-
-
0031836392
-
Current perspectives on pain upon injection of drugs
-
Brazeau GA et al. Current perspectives on pain upon injection of drugs. J Pharm Sci 1998 87 : 667 677.
-
(1998)
J Pharm Sci
, vol.87
, pp. 667-677
-
-
Brazeau, G.A.1
-
2
-
-
0346729796
-
SolEmuls(R): Novel technology for the formulation of i.v. emulsions with poorly soluble drugs
-
Muller RH et al. SolEmuls(R): novel technology for the formulation of i.v. emulsions with poorly soluble drugs. Int J Pharm 2004 269 : 293 302.
-
(2004)
Int J Pharm
, vol.269
, pp. 293-302
-
-
Muller, R.H.1
-
3
-
-
0036742053
-
Poor aqueous solubility - An industry wide problem in drug discovery
-
Lipinski C. Poor aqueous solubility - an industry wide problem in drug discovery. American Pharm Rev 2002 5 : 82 85.
-
(2002)
American Pharm Rev
, vol.5
, pp. 82-85
-
-
Lipinski, C.1
-
4
-
-
0024997481
-
A comparative study on irritation and residue aspects of five oxytetracycline formulations administered intramuscularly to calves, pigs and sheep
-
Nouws JF et al. A comparative study on irritation and residue aspects of five oxytetracycline formulations administered intramuscularly to calves, pigs and sheep. Vet Quart 1990 12 : 129 138.
-
(1990)
Vet Quart
, vol.12
, pp. 129-138
-
-
Nouws, J.F.1
-
5
-
-
0024392051
-
Physicochemical properties of binary organic cosolvent-water mixtures and their relationships to muscle damage following intramuscular injection
-
Brazeau GA, Fung HL. Physicochemical properties of binary organic cosolvent-water mixtures and their relationships to muscle damage following intramuscular injection. J Parenter Sci Technol 1989 43 : 144 149.
-
(1989)
J Parenter Sci Technol
, vol.43
, pp. 144-149
-
-
Brazeau, G.A.1
Fung, H.L.2
-
6
-
-
0024450121
-
Use of an in vitro model for the assessment of muscle damage from intramuscular injections: In vitro-in vivo correlation and predictability with mixed solvent systems
-
Brazeau GA, Fung HL. Use of an in vitro model for the assessment of muscle damage from intramuscular injections: in vitro-in vivo correlation and predictability with mixed solvent systems. Pharm Res 1989 6 : 766 771.
-
(1989)
Pharm Res
, vol.6
, pp. 766-771
-
-
Brazeau, G.A.1
Fung, H.L.2
-
7
-
-
0025145763
-
Effect of organic cosolvent-induced skeletal muscle damage on the bioavailability of intramuscular [14C]diazepam
-
Brazeau GA, Fung HL. Effect of organic cosolvent-induced skeletal muscle damage on the bioavailability of intramuscular [14C]diazepam. J Pharm Sci 1990 79 : 773 777.
-
(1990)
J Pharm Sci
, vol.79
, pp. 773-777
-
-
Brazeau, G.A.1
Fung, H.L.2
-
8
-
-
0029846340
-
Solubility principles and practices for parenteral drug dosage form development
-
Sweetana S, Akers MJ. Solubility principles and practices for parenteral drug dosage form development. PDA J Pharm Sci Technol 1996 50 : 330 342.
-
(1996)
PDA J Pharm Sci Technol
, vol.50
, pp. 330-342
-
-
Sweetana, S.1
Akers, M.J.2
-
9
-
-
0029940055
-
Studies in phlebitis VIII: Evaluations of pH solubilized intravenous dexverapamil formulations
-
Simamora P et al. Studies in phlebitis VIII: evaluations of pH solubilized intravenous dexverapamil formulations. PDA J Pharm Sci Technol 1996 50 : 123 128.
-
(1996)
PDA J Pharm Sci Technol
, vol.50
, pp. 123-128
-
-
Simamora, P.1
-
10
-
-
0345306613
-
Inhibitory effect of sulfobutyl ether betacyclodextrin on DY-9760e-induced cellular damage: In vitro and in vivo studies
-
Nagase Y et al. Inhibitory effect of sulfobutyl ether betacyclodextrin on DY-9760e-induced cellular damage: in vitro and in vivo studies. J Pharm Sci 2003 92 : 2466 2474.
-
(2003)
J Pharm Sci
, vol.92
, pp. 2466-2474
-
-
Nagase, Y.1
-
13
-
-
0017383869
-
Intramuscular injections and bioavailability
-
Tuttle CB. Intramuscular injections and bioavailability. Am J Hosp Pharm 1977 34 : 965 968.
-
(1977)
Am J Hosp Pharm
, vol.34
, pp. 965-968
-
-
Tuttle, C.B.1
-
14
-
-
0025344957
-
The use of oil-in-water emulsions as a vehicle for parenteral drug administration
-
Prankerd RJ, Stella VJ. The use of oil-in-water emulsions as a vehicle for parenteral drug administration. J Parenter Sci Technol 1990 44 : 139 149.
-
(1990)
J Parenter Sci Technol
, vol.44
, pp. 139-149
-
-
Prankerd, R.J.1
Stella, V.J.2
-
15
-
-
0023676918
-
Preliminary development and evaluation of a parenteral emulsion formulation of penclomedine (NSC-338720; 3,5-dichloro-2,4-dimethoxy-6- trichloromethylpyridine): A novel, practically water insoluble cytotoxic agent
-
Prankerd RJ et al. Preliminary development and evaluation of a parenteral emulsion formulation of penclomedine (NSC-338720; 3,5-dichloro-2,4-dimethoxy-6- trichloromethylpyridine): a novel, practically water insoluble cytotoxic agent. J Parenter Sci Technol 1988 42 : 76 81.
-
(1988)
J Parenter Sci Technol
, vol.42
, pp. 76-81
-
-
Prankerd, R.J.1
-
16
-
-
0032920457
-
Preparation and evaluation of flurbiprofen- loaded microemulsion for parenteral delivery
-
Park K-M, Kim C-K. Preparation and evaluation of flurbiprofen- loaded microemulsion for parenteral delivery. Int J Pharm 1999 181 : 173 179.
-
(1999)
Int J Pharm
, vol.181
, pp. 173-179
-
-
Park, K.-M.1
Kim, C.-K.2
-
17
-
-
0037925140
-
Comparative pharmacokinetics and safety of a novel lyophilized amphotericin B lecithin-based oil-water microemulsion and amphotericin B deoxycholate in animal models
-
Brime B et al. Comparative pharmacokinetics and safety of a novel lyophilized amphotericin B lecithin-based oil-water microemulsion and amphotericin B deoxycholate in animal models. J Antimicrob Chemother 2003 52 : 103 109.
-
(2003)
J Antimicrob Chemother
, vol.52
, pp. 103-109
-
-
Brime, B.1
-
18
-
-
0033430984
-
Microemulsions: An overview and pharmaceutical applications
-
Tenjarla S. Microemulsions: an overview and pharmaceutical applications. Crit Rev Ther Drug Carrier Syst 1999 16 : 461 521.
-
(1999)
Crit Rev Ther Drug Carrier Syst
, vol.16
, pp. 461-521
-
-
Tenjarla, S.1
-
19
-
-
0037745094
-
Lecithin-based oil-in-water microemulsions for parenteral use: Pseudoternary phase diagrams, characterization and toxicity studies
-
Moreno MA et al. Lecithin-based oil-in-water microemulsions for parenteral use: pseudoternary phase diagrams, characterization and toxicity studies. J Pharm Sci 2003 92 : 1428 1437.
-
(2003)
J Pharm Sci
, vol.92
, pp. 1428-1437
-
-
Moreno, M.A.1
-
20
-
-
0034961459
-
Lyophilized lecithin based oil-water microemulsions as a new and low toxic delivery system for amphotericin B
-
Moreno MA et al. Lyophilized lecithin based oil-water microemulsions as a new and low toxic delivery system for amphotericin B. Pharm Res 2001 18 : 344 351.
-
(2001)
Pharm Res
, vol.18
, pp. 344-351
-
-
Moreno, M.A.1
-
21
-
-
0036159683
-
Microemulsion formulation of clonixic acid: Solubility enhancement and pain reduction
-
Lee JM et al. Microemulsion formulation of clonixic acid: solubility enhancement and pain reduction. J Pharm Pharmacol 2002 54 : 43 49.
-
(2002)
J Pharm Pharmacol
, vol.54
, pp. 43-49
-
-
Lee, J.M.1
-
22
-
-
0031054513
-
Pharmaceutical applications of cyclodextrins. III. Toxicological issues and safety evaluation
-
Irie T, Uekama K. Pharmaceutical applications of cyclodextrins. III. Toxicological issues and safety evaluation. J Pharm Sci 1997 86 : 147 162.
-
(1997)
J Pharm Sci
, vol.86
, pp. 147-162
-
-
Irie, T.1
Uekama, K.2
-
23
-
-
0031657040
-
Comparison of the effects of potential parenteral vehicles for poorly water soluble anticancer drugs (organic cosolvents and cyclodextrin solutions) on cultured endothelial cells (HUV-EC)
-
Medlicott NJ et al. Comparison of the effects of potential parenteral vehicles for poorly water soluble anticancer drugs (organic cosolvents and cyclodextrin solutions) on cultured endothelial cells (HUV-EC). J Pharm Sci 1998 87 : 1138 1143.
-
(1998)
J Pharm Sci
, vol.87
, pp. 1138-1143
-
-
Medlicott, N.J.1
-
24
-
-
0029048935
-
The effect of SBE4-[beta]-CD on i.m. prednisolone pharmacokinetics and tissue damage in rabbits: Comparison to a co-solvent solution and a water-soluble prodrug
-
Stella VJ et al. The effect of SBE4-[beta]-CD on i.m. prednisolone pharmacokinetics and tissue damage in rabbits: Comparison to a co-solvent solution and a water-soluble prodrug. Int J Pharm 1995 120 : 197 204.
-
(1995)
Int J Pharm
, vol.120
, pp. 197-204
-
-
Stella, V.J.1
-
25
-
-
0028134662
-
A comparison of two formulations for etomidate, 2-hydroxypropyl-beta- cyclodextrin (HPCD) and propylene glycol
-
Doenicke A et al. A comparison of two formulations for etomidate, 2-hydroxypropyl-beta-cyclodextrin (HPCD) and propylene glycol. Anesth Analg 1994 79 : 933 939.
-
(1994)
Anesth Analg
, vol.79
, pp. 933-939
-
-
Doenicke, A.1
-
26
-
-
0029852699
-
Pharmaceutical applications of cyclodextrins. 2. in vivo drug delivery
-
Rajewski RA, Stella VJ. Pharmaceutical applications of cyclodextrins. 2. In vivo drug delivery. J Pharm Sci 1996 85 : 1142 1169.
-
(1996)
J Pharm Sci
, vol.85
, pp. 1142-1169
-
-
Rajewski, R.A.1
Stella, V.J.2
-
27
-
-
0031786221
-
Prevention of precipitation of phenytoin in an infusion fluid by hydroxypropyl beta-cyclodextrin
-
McDonald C, Muzumdar PP. Prevention of precipitation of phenytoin in an infusion fluid by hydroxypropyl beta-cyclodextrin. J Clin Pharm Ther 1998 23 : 235 239.
-
(1998)
J Clin Pharm Ther
, vol.23
, pp. 235-239
-
-
McDonald, C.1
Muzumdar, P.P.2
-
28
-
-
0033855301
-
Development and testing of an improved parenteral formulation of phenytoin using 2-hydroxypropylbeta-cyclodextrin
-
Blanchard J et al. Development and testing of an improved parenteral formulation of phenytoin using 2-hydroxypropylbeta-cyclodextrin. Pharmaceut Dev Tech 2000 5 : 333 338.
-
(2000)
Pharmaceut Dev Tech
, vol.5
, pp. 333-338
-
-
Blanchard, J.1
-
30
-
-
0031717684
-
Ricobendazole kinetics and availability following subcutaneous administration of a novel injectable formulation to calves
-
Lanusse CE et al. Ricobendazole kinetics and availability following subcutaneous administration of a novel injectable formulation to calves. Res Vet Sci 1998 65 : 5 10.
-
(1998)
Res Vet Sci
, vol.65
, pp. 5-10
-
-
Lanusse, C.E.1
-
31
-
-
0034929799
-
Albendazole sulphoxide enantiomeric ratios in plasma and target tissues after intravenous administration of ricobendazole to cattle
-
Cristofol C et al. Albendazole sulphoxide enantiomeric ratios in plasma and target tissues after intravenous administration of ricobendazole to cattle. J Vet Pharmacol Ther 2001 24 : 117 124.
-
(2001)
J Vet Pharmacol Ther
, vol.24
, pp. 117-124
-
-
Cristofol, C.1
-
32
-
-
0034434515
-
Comparative disposition of ricobendazole enantiomers after intravenous and subcutaneous administration of a racemic formulation to calves
-
Cristofol C et al. Comparative disposition of ricobendazole enantiomers after intravenous and subcutaneous administration of a racemic formulation to calves. Biopharm Drug Dispos 2000 21 : 303 311.
-
(2000)
Biopharm Drug Dispos
, vol.21
, pp. 303-311
-
-
Cristofol, C.1
-
33
-
-
0034930861
-
Pharmacokinetics of ricobendazole in calves
-
Formentini EA et al. Pharmacokinetics of ricobendazole in calves. J Vet Pharmacol Ther 2001 24 : 199 202.
-
(2001)
J Vet Pharmacol Ther
, vol.24
, pp. 199-202
-
-
Formentini, E.A.1
-
34
-
-
20344362165
-
Physicochemical characterization of ricobendazole. I. Solubility, lipophilicity and ionization characteristics
-
Wu Z et al. Physicochemical characterization of ricobendazole. I. Solubility, lipophilicity and ionization characteristics. J Pharm Sci 2005 94 : 983 993.
-
(2005)
J Pharm Sci
, vol.94
, pp. 983-993
-
-
Wu, Z.1
-
35
-
-
26444539529
-
An in vitro kinetic method for detection of precipitation of poorly soluble drugs
-
Wu Z et al. An in vitro kinetic method for detection of precipitation of poorly soluble drugs. Int J Pharm 2005 304 : 1 3.
-
(2005)
Int J Pharm
, vol.304
, pp. 1-3
-
-
Wu, Z.1
-
36
-
-
0033803690
-
Pharmacokinetics of sulphadoxine and trimethoprim and tissue irritation caused by two sulphadoxinetrimethoprim containing products after subcutaneous administration in pre-ruminant calves
-
Kaartinen L et al. Pharmacokinetics of sulphadoxine and trimethoprim and tissue irritation caused by two sulphadoxinetrimethoprim containing products after subcutaneous administration in pre-ruminant calves. Vet Res 2000 31 : 517 526.
-
(2000)
Vet Res
, vol.31
, pp. 517-526
-
-
Kaartinen, L.1
-
37
-
-
23444444895
-
Development and optimization of a rapid HPLC method for analysis of ricobendazole and albendazole sulfone in sheep plasma
-
Wu Z et al. Development and optimization of a rapid HPLC method for analysis of ricobendazole and albendazole sulfone in sheep plasma. J Pharm Biomed Anal 2005 39 : 225 232.
-
(2005)
J Pharm Biomed Anal
, vol.39
, pp. 225-232
-
-
Wu, Z.1
-
39
-
-
1242337285
-
Solubilizing excipients in oral and injectable formulations
-
Strickley RG. Solubilizing excipients in oral and injectable formulations. Pharm Res 2004 21 : 201 230.
-
(2004)
Pharm Res
, vol.21
, pp. 201-230
-
-
Strickley, R.G.1
-
40
-
-
0000792056
-
Tissue irritation evaluation of potential parenteral vehicles
-
Hem SL et al. Tissue irritation evaluation of potential parenteral vehicles. Drug Dev Commun 1974 1 : 471 477.
-
(1974)
Drug Dev Commun
, vol.1
, pp. 471-477
-
-
Hem, S.L.1
-
41
-
-
0020515137
-
The clearance of oily vehicles following intramuscular and subcutaneous injections in rabbits
-
Howard JR, Hadgraft J. The clearance of oily vehicles following intramuscular and subcutaneous injections in rabbits. Int J Pharm 1983 16 : 31 39.
-
(1983)
Int J Pharm
, vol.16
, pp. 31-39
-
-
Howard, J.R.1
Hadgraft, J.2
-
43
-
-
0031714526
-
Human studies on polyglycerol polyricinoleate (PGPR)
-
Wilson R, Smith M. Human studies on polyglycerol polyricinoleate (PGPR). Food Chem Toxicol 1998 36 : 743 745.
-
(1998)
Food Chem Toxicol
, vol.36
, pp. 743-745
-
-
Wilson, R.1
Smith, M.2
-
44
-
-
0035848386
-
Sustained elevated plasma aprotinin concentration in mice following intraperitoneal injections of w/o emulsions incorporating aprotinin
-
Bjerregaard S et al. Sustained elevated plasma aprotinin concentration in mice following intraperitoneal injections of w/o emulsions incorporating aprotinin. J Control Release 2001 12 : 87 98.
-
(2001)
J Control Release
, vol.12
, pp. 87-98
-
-
Bjerregaard, S.1
-
45
-
-
0035857707
-
Parenteral water/oil emulsions containing hydrophilic compounds with enhanced in vivo retention: Formulation, rheological characterisation and study of in vivo fate using whole body gamma-scintigraphy
-
Bjerregaard S et al. Parenteral water/oil emulsions containing hydrophilic compounds with enhanced in vivo retention: formulation, rheological characterisation and study of in vivo fate using whole body gamma-scintigraphy. Int J Pharm 2001 14 : 13 27.
-
(2001)
Int J Pharm
, vol.14
, pp. 13-27
-
-
Bjerregaard, S.1
-
46
-
-
0030052420
-
Preliminary studies of the toxic effects of nonionic surfactants derived from lysine
-
Macian M et al. Preliminary studies of the toxic effects of nonionic surfactants derived from lysine. Toxicology 1996 106 : 1 9.
-
(1996)
Toxicology
, vol.106
, pp. 1-9
-
-
MacIan, M.1
-
47
-
-
0036001404
-
Utility of MTT assay in three-dimensional cultured human skin model as an alternative for draize skin irritation test: Approach using diffusion law of irritant in skin and toxicokinetics-toxicodynamics correlation
-
Watanabe T et al. Utility of MTT assay in three-dimensional cultured human skin model as an alternative for draize skin irritation test: approach using diffusion law of irritant in skin and toxicokinetics-toxicodynamics correlation. Pharm Res 2002 19 : 669 675.
-
(2002)
Pharm Res
, vol.19
, pp. 669-675
-
-
Watanabe, T.1
-
48
-
-
0142244248
-
Aspects of the pharmacokinetics of albendazole sulphoxide in sheep
-
Goudah A. Aspects of the pharmacokinetics of albendazole sulphoxide in sheep. Vet Res Commun 2003 27 : 555 566.
-
(2003)
Vet Res Commun
, vol.27
, pp. 555-566
-
-
Goudah, A.1
-
49
-
-
1642304142
-
Assessment of primary eye and skin irritants by in vitro cytotoxicity and phototoxicity models: An in vitro approach of new arginine-based surfactant-induced irritation
-
Benavides T et al. Assessment of primary eye and skin irritants by in vitro cytotoxicity and phototoxicity models: an in vitro approach of new arginine-based surfactant-induced irritation. Toxicology 2004 197 : 229 237.
-
(2004)
Toxicology
, vol.197
, pp. 229-237
-
-
Benavides, T.1
|