Inhibitory Effect of Sulfobutyl Ether β-Cyclodextrin on DY-9760e-Induced Cellular Damage: In Vitro and in Vivo Studies

Journal of Pharmaceutical Sciences

Volumn 92, Issue 12, 2003, Pages 2466-2474

  Nagase, Yukihiko ^a   Arima, Hidetoshi ^b   Wada, Koki ^b   Sugawara, Tadaki ^a   Satoh, Hiroshi ^a   Hirayama, Fumitoshi ^b   Uekama, Kaneto ^b  

^a DAIICHI SANKYO CO   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

2 hydroxypropyl cyclodextrin; Cytotoxicity; DY 9760e; Inclusion complex; Sulfobutyl ether cyclodextrin; Vascular damage

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; 3 [2 [4 (3 CHLORO 2 METHYLPHENYL) 1 PIPERAZINYL]ETHYL] 5,6 DIMETHOXY 1 (4 IMIDAZOLYLMETHYL) 1H INDAZOLE; BETA CYCLODEXTRIN; BETA CYCLODEXTRIN DERIVATIVE; BETA CYCLODEXTRIN SULFOBUTYL ETHER; CALMODULIN INHIBITOR; DY 9760E; MALTOSYL BETA CYCLODEXTRIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DESQUAMATION; ELECTRICITY; ENDOTHELIUM CELL; EXTERNAL EAR; HUMAN; HUMAN CELL; HYDROPHOBICITY; NONHUMAN; RABBIT; UMBILICAL VEIN; VASCULAR ENDOTHELIUM; VASCULITIS; VEIN THROMBOSIS;

EID: 0345306613     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10517     Document Type: Article

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