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Volumn 51, Issue 3, 2010, Pages 243-250

Cytogenetic and molecular characterization of plutonium-induced rat osteosarcomas

Author keywords

Alpha particle emitter; Chromosome aberrations; Ionizing radiation; Osteosarcoma

Indexed keywords

GENE EXPRESSION; PLUTONIUM; RADIATION SHIELDING; RATS; TUMORS;

EID: 77954003512     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1269/jrr.09110     Document Type: Article
Times cited : (5)

References (46)
  • 1
    • 18044364798 scopus 로고    scopus 로고
    • Overview of sarcomas in the adolescent and young adult population
    • Herzog CE (2005) Overview of sarcomas in the adolescent and young adult population. J Pediatr Hematol Oncol 27: 215-218.
    • (2005) J Pediatr Hematol Oncol , vol.27 , pp. 215-218
    • Herzog, C.E.1
  • 2
    • 0030848527 scopus 로고    scopus 로고
    • Cancer incidence after retinoblastoma. Radiation dose and sarcoma risk
    • Wong FL, et al (1997) Cancer incidence after retinoblastoma. Radiation dose and sarcoma risk. Jama 278: 1262-1267.
    • (1997) Jama , vol.278 , pp. 1262-1267
    • Wong, F.L.1
  • 3
    • 0034256517 scopus 로고    scopus 로고
    • Radiation-induced sarcoma
    • Patel SR (2000) Radiation-induced sarcoma. Curr Treat Options Oncol 1: 258-261.
    • (2000) Curr Treat Options Oncol , vol.1 , pp. 258-261
    • Patel, S.R.1
  • 4
    • 27144496377 scopus 로고    scopus 로고
    • Radiation-induced osteosarcomas in the pediatric population
    • Koshy M, et al (2005) Radiation-induced osteosarcomas in the pediatric population. Int J Radiat Oncol Biol Phys 63: 1169-1174.
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 1169-1174
    • Koshy, M.1
  • 5
    • 0018077471 scopus 로고
    • Dose-response relationships for female radium dial workers
    • Rowland RE, Stehney AF and Lucas HF Jr. (1978) Dose-response relationships for female radium dial workers. Radiat Res 76: 368-383.
    • (1978) Radiat Res , vol.76 , pp. 368-383
    • Rowland, R.E.1    Stehney, A.F.2    Lucas, J.H.F.3
  • 6
    • 0033817649 scopus 로고    scopus 로고
    • Bone cancers in Mayak workers
    • Koshurnikova NA, et al (2000) Bone cancers in Mayak workers. Radiat Res 154: 237-245.
    • (2000) Radiat Res , vol.154 , pp. 237-245
    • Koshurnikova, N.A.1
  • 7
    • 0034003187 scopus 로고    scopus 로고
    • Induction of malignant bone tumors in radium-224 patients: Risk estimates based on the improved dosimetry
    • Nekolla EA, et al (2000) Induction of malignant bone tumors in radium-224 patients: risk estimates based on the improved dosimetry. Radiat Res 153: 93-103.
    • (2000) Radiat Res , vol.153 , pp. 93-103
    • Nekolla, E.A.1
  • 8
    • 0141799898 scopus 로고    scopus 로고
    • Mechanisms of sarcoma development
    • Helman LJ and Meltzer P (2003) Mechanisms of sarcoma development. Nat Rev Cancer 3: 685-694.
    • (2003) Nat Rev Cancer , vol.3 , pp. 685-694
    • Helman, L.J.1    Meltzer, P.2
  • 9
    • 0032837702 scopus 로고    scopus 로고
    • Cytogenetic study of eight new cases of radiation-induced solid tumors
    • Chauveinc L, et al (1999) Cytogenetic study of eight new cases of radiation-induced solid tumors. Cancer genetics and cytogenetics 114: 1-8.
    • (1999) Cancer Genetics and Cytogenetics , vol.114 , pp. 1-8
    • Chauveinc, L.1
  • 10
    • 0033992096 scopus 로고    scopus 로고
    • Radiation-associated sarcomas are characterized by complex karyotypes with frequent rearrangements of chromosome arm 3p
    • Mertens F, et al (2000) Radiation-associated sarcomas are characterized by complex karyotypes with frequent rearrangements of chromosome arm 3p. Cancer genetics and cytogenet-ics 116: 89-96.
    • (2000) Cancer Genetics and Cytogenet-ics , vol.116 , pp. 89-96
    • Mertens, F.1
  • 11
    • 18244365152 scopus 로고    scopus 로고
    • Genome instability in secondary solid tumors developing after radiotherapy of bilateral retino-blastoma
    • Lefevre SH, et al (2001) Genome instability in secondary solid tumors developing after radiotherapy of bilateral retino-blastoma. Oncogene 20: 8092-8099.
    • (2001) Oncogene , vol.20 , pp. 8092-8099
    • Lefevre, S.H.1
  • 12
    • 0035477483 scopus 로고    scopus 로고
    • Comparative genomic hybridization of postirradiation sarcomas
    • Tarkkanen M, et al (2001) Comparative genomic hybridization of postirradiation sarcomas. Cancer 92: 1992-1998.
    • (2001) Cancer , vol.92 , pp. 1992-1998
    • Tarkkanen, M.1
  • 13
    • 0037202212 scopus 로고    scopus 로고
    • Cytogenetics and molecular genetics of bone and soft-tissue tumors
    • Sandberg AA (2002) Cytogenetics and molecular genetics of bone and soft-tissue tumors. Am J Med Genet 115: 189-193.
    • (2002) Am J Med Genet , vol.115 , pp. 189-193
    • Sandberg, A.A.1
  • 14
    • 0026417618 scopus 로고
    • Analysis of alterations in the retinoblas-toma gene and tumor grade in bone and soft-tissue sarcomas
    • Wunder JS, et al (1991) Analysis of alterations in the retinoblas-toma gene and tumor grade in bone and soft-tissue sarcomas. J Natl Cancer Inst 83: 194-200.
    • (1991) J Natl Cancer Inst , vol.83 , pp. 194-200
    • Wunder, J.S.1
  • 15
    • 0028276710 scopus 로고
    • Mutation spectrum of the retino-blastoma gene in osteosarcomas
    • Wadayama B, et al (1994) Mutation spectrum of the retino-blastoma gene in osteosarcomas. Cancer Res 54: 3042-3048.
    • (1994) Cancer Res , vol.54 , pp. 3042-3048
    • Wadayama, B.1
  • 16
    • 0029789170 scopus 로고    scopus 로고
    • Loss of heterozygosity and microsat-ellite instability at the retinoblastoma locus in osteosarcomas
    • Belchis DA, et al (1996) Loss of heterozygosity and microsat-ellite instability at the retinoblastoma locus in osteosarcomas. Diagn Mol Pathol 5: 214-219.
    • (1996) Diagn Mol Pathol , vol.5 , pp. 214-219
    • Belchis, D.A.1
  • 17
    • 0029118134 scopus 로고
    • Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas-relationship to amplification and mRNA levels of CDK4 and CCND1
    • Maelandsmo GM, et al (1995) Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas-relationship to amplification and mRNA levels of CDK4 and CCND1. Br J Cancer 72: 393-398.
    • (1995) Br J Cancer , vol.72 , pp. 393-398
    • Maelandsmo, G.M.1
  • 18
    • 15144353460 scopus 로고    scopus 로고
    • Amplification of the CDK4 gene in sarcomas: Tumor specificity and relationship with the RB gene mutation
    • Kanoe H, et al (1998) Amplification of the CDK4 gene in sarcomas: tumor specificity and relationship with the RB gene mutation. Anticancer Res 18: 2317-2321.
    • (1998) Anticancer Res , vol.18 , pp. 2317-2321
    • Kanoe, H.1
  • 19
    • 0035915773 scopus 로고    scopus 로고
    • Loss of p16(INK4a) expression correlates with decreased survival in pediatric osteosarcomas
    • Maitra A, et al (2001) Loss of p16(INK4a) expression correlates with decreased survival in pediatric osteosarcomas. Int J Cancer 95: 34-38.
    • (2001) Int J Cancer , vol.95 , pp. 34-38
    • Maitra, A.1
  • 20
    • 0036211680 scopus 로고    scopus 로고
    • Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines
    • Park YB, et al (2002) Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines. Cancer Genet Cytogenet 133: 105-111.
    • (2002) Cancer Genet Cytogenet , vol.133 , pp. 105-111
    • Park, Y.B.1
  • 21
    • 0030964879 scopus 로고    scopus 로고
    • P53 and MDM2 alterations in osteosa-rcomas: Correlation with clinicopathologic features and prolif-erative rate
    • Lonardo F, et al (1997) P53 and MDM2 alterations in osteosa-rcomas: correlation with clinicopathologic features and prolif-erative rate. Cancer 79: 1541-1547.
    • (1997) Cancer , vol.79 , pp. 1541-1547
    • Lonardo, F.1
  • 22
    • 0025665155 scopus 로고
    • Frequency and structure of p53 rearrangements in human osteosarcoma
    • Miller CW, et al (1990) Frequency and structure of p53 rearrangements in human osteosarcoma. Cancer Res 50: 7950-7954.
    • (1990) Cancer Res , vol.50 , pp. 7950-7954
    • Miller, C.W.1
  • 23
    • 0027295746 scopus 로고
    • Screening for TP53 mutations in osteosarcomas using constant denaturant gel electrophore-sis (CDGE)
    • Smith-Sorensen B, et al (1993) Screening for TP53 mutations in osteosarcomas using constant denaturant gel electrophore-sis (CDGE). Hum Mutat 2: 274-285.
    • (1993) Hum Mutat , vol.2 , pp. 274-285
    • Smith-Sorensen, B.1
  • 24
    • 0026443949 scopus 로고
    • A significant proportion of patients with osteosarcoma may belong to Li-Fraumeni cancer families
    • Porter DE, et al (1992) A significant proportion of patients with osteosarcoma may belong to Li-Fraumeni cancer families. J Bone Joint Surg Br 74: 883-886.
    • (1992) J Bone Joint Surg Br , vol.74 , pp. 883-886
    • Porter, D.E.1
  • 25
    • 0031470962 scopus 로고    scopus 로고
    • Expression of transforming growth factor-beta (TGF-beta) isoforms in osteosarcomas: TGF-beta3 is related to disease progression
    • Kloen P, et al (1997) Expression of transforming growth factor-beta (TGF-beta) isoforms in osteosarcomas: TGF-beta3 is related to disease progression. Cancer 80: 2230-2239.
    • (1997) Cancer , vol.80 , pp. 2230-2239
    • Kloen, P.1
  • 26
    • 0031704545 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor receptor, IGF-1, and IGF-2 in primary and metastatic osteosarcoma
    • Burrow S, et al (1998) Expression of insulin-like growth factor receptor, IGF-1, and IGF-2 in primary and metastatic osteosarcoma. J Surg Oncol 69: 21-27.
    • (1998) J Surg Oncol , vol.69 , pp. 21-27
    • Burrow, S.1
  • 27
    • 0343628689 scopus 로고    scopus 로고
    • Platelet-derived growth factor-AA and-alpha receptor expression suggests an autocrine and/or paracrine loop in osteosarcoma
    • Sulzbacher I, et al (2000) Platelet-derived growth factor-AA and-alpha receptor expression suggests an autocrine and/or paracrine loop in osteosarcoma. Mod Pathol 13: 632-637.
    • (2000) Mod Pathol , vol.13 , pp. 632-637
    • Sulzbacher, I.1
  • 28
    • 0030922893 scopus 로고    scopus 로고
    • Bone tumor location in dogs given skeletal irradiation by 239Pu or 226Ra
    • Lloyd RD, et al (1997) Bone tumor location in dogs given skeletal irradiation by 239Pu or 226Ra. Health Phys 73: 684-689.
    • (1997) Health Phys , vol.73 , pp. 684-689
    • Lloyd, R.D.1
  • 29
    • 2942606642 scopus 로고    scopus 로고
    • The specific induction of osteosarcomas in different mouse strains after injections of 239Pu citrate
    • Oghiso Y and Yamada Y (2003) The specific induction of osteosarcomas in different mouse strains after injections of 239Pu citrate. J Radiat Res (Tokyo) 44: 125-132.
    • (2003) J Radiat Res (Tokyo) , vol.44 , pp. 125-132
    • Oghiso, Y.1    Yamada, Y.2
  • 30
    • 67650077096 scopus 로고    scopus 로고
    • Gene expression profiling of alpha-radiation-induced rat osteosarcomas: Identification of dysregu-lated genes involved in radiation-induced tumorigenesis of bone
    • Daino K, et al (2009) Gene expression profiling of alpha-radiation-induced rat osteosarcomas: Identification of dysregu-lated genes involved in radiation-induced tumorigenesis of bone. Int J Cancer 125: 612-620.
    • (2009) Int J Cancer , vol.125 , pp. 612-620
    • Daino, K.1
  • 31
    • 0016353218 scopus 로고
    • Separation of parathyroid hormone and calcitonin-sensitive cells from non-responsive bone cells
    • Wong G and Cohn DV (1974) Separation of parathyroid hormone and calcitonin-sensitive cells from non-responsive bone cells. Nature 252: 713-715.
    • (1974) Nature , vol.252 , pp. 713-715
    • Wong, G.1    Cohn, D.V.2
  • 32
    • 0033853229 scopus 로고    scopus 로고
    • CGH analysis of radon-induced rat lung tumors indicates similarities with human lung cancers
    • Dano L, et al (2000) CGH analysis of radon-induced rat lung tumors indicates similarities with human lung cancers. Genes Chromosomes Cancer 29: 1-8.
    • (2000) Genes Chromosomes Cancer , vol.29 , pp. 1-8
    • Dano, L.1
  • 33
    • 0037447929 scopus 로고    scopus 로고
    • In vitro aging of rat lung cells. Down-regulation of telomerase activity and continuous decrease of telomere length are not incompatible with malignant transformation
    • Petitot F, et al (2003) In vitro aging of rat lung cells. Down-regulation of telomerase activity and continuous decrease of telomere length are not incompatible with malignant transformation. Exp Cell Res 286: 30-39.
    • (2003) Exp Cell Res , vol.286 , pp. 30-39
    • Petitot, F.1
  • 34
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of realtime quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J, et al (2002) Accurate normalization of realtime quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1
  • 35
    • 0035866809 scopus 로고    scopus 로고
    • Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hyper-methylation
    • Evron E, et al (2001) Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hyper-methylation. Cancer Res 61: 2782-2787.
    • (2001) Cancer Res , vol.61 , pp. 2782-2787
    • Evron, E.1
  • 36
    • 0038455147 scopus 로고    scopus 로고
    • Absence of cyclin D2 expression is associated with promoter hypermethylation in gastric cancer
    • Yu J, et al (2003) Absence of cyclin D2 expression is associated with promoter hypermethylation in gastric cancer. Br J Cancer 88: 1560-1565.
    • (2003) Br J Cancer , vol.88 , pp. 1560-1565
    • Yu, J.1
  • 37
    • 7244254368 scopus 로고    scopus 로고
    • Genetic analysis of fibrosarcoma of bone, a rare tumour entity closely related to osteosarcoma and malignant fibrous histiocytoma of bone
    • Hattinger CM, et al (2004) Genetic analysis of fibrosarcoma of bone, a rare tumour entity closely related to osteosarcoma and malignant fibrous histiocytoma of bone. Eur J Cell Biol 83: 483-491.
    • (2004) Eur J Cell Biol , vol.83 , pp. 483-491
    • Hattinger, C.M.1
  • 38
    • 19944427138 scopus 로고    scopus 로고
    • Gene amplifications in osteosarcoma-CGH microarray analysis
    • Atiye J, et al (2005) Gene amplifications in osteosarcoma-CGH microarray analysis. Genes Chromosomes Cancer 42: 158-163.
    • (2005) Genes Chromosomes Cancer , vol.42 , pp. 158-163
    • Atiye, J.1
  • 39
    • 0027249809 scopus 로고
    • Sporadic amplification of the MYC gene in human osteosarcomas
    • Ladanyi M, et al (1993) Sporadic amplification of the MYC gene in human osteosarcomas. Diagn Mol Pathol 2: 163-167.
    • (1993) Diagn Mol Pathol , vol.2 , pp. 163-167
    • Ladanyi, M.1
  • 40
    • 0029896367 scopus 로고    scopus 로고
    • Genomic imprinting of human p57KIP2 and its reduced expression in Wilms' tumors
    • Hatada I, et al (1996) Genomic imprinting of human p57KIP2 and its reduced expression in Wilms' tumors. Hum Mol Genet 5: 783-788.
    • (1996) Hum Mol Genet , vol.5 , pp. 783-788
    • Hatada, I.1
  • 41
    • 0034733047 scopus 로고    scopus 로고
    • Mutation and expression of the p27KIP1 and p57KIP2 genes in human gastric cancer
    • Shin JY, et al (2000) Mutation and expression of the p27KIP1 and p57KIP2 genes in human gastric cancer. Exp Mol Med 32: 79-83.
    • (2000) Exp Mol Med , vol.32 , pp. 79-83
    • Shin, J.Y.1
  • 42
    • 14044278146 scopus 로고    scopus 로고
    • Multiple mechanisms downregu-late CDKN1C in human bladder cancer
    • Hoffmann MJ, et al (2005) Multiple mechanisms downregu-late CDKN1C in human bladder cancer. Int J Cancer 114: 406-413.
    • (2005) Int J Cancer , vol.114 , pp. 406-413
    • Hoffmann, M.J.1
  • 43
    • 0041386110 scopus 로고    scopus 로고
    • TP53 and mutations in human cancer
    • Szymanska K and Hainaut P (2003) TP53 and mutations in human cancer. Acta biochim Polon 50: 231-238.
    • (2003) Acta Biochim Polon , vol.50 , pp. 231-238
    • Szymanska, K.1    Hainaut, P.2
  • 44
    • 0036251645 scopus 로고    scopus 로고
    • TP53: A key gene in human cancer
    • Guimaraes DP and Hainaut P (2002) TP53: a key gene in human cancer. Biochimie 84: 83-93.
    • (2002) Biochimie , vol.84 , pp. 83-93
    • Guimaraes, D.P.1    Hainaut, P.2
  • 45
    • 33745609248 scopus 로고    scopus 로고
    • Specific TP53 mutation pattern in radiation-induced sarcomas
    • Gonin-Laurent N, et al (2006) Specific TP53 mutation pattern in radiation-induced sarcomas. Carcinogenesis 27: 1266-1272.
    • (2006) Carcinogenesis , vol.27 , pp. 1266-1272
    • Gonin-Laurent, N.1
  • 46
    • 0346731877 scopus 로고    scopus 로고
    • The distribution of plutonium between the mineral and organic components of rat bone: A biochemical study after in vivo and in vitro contamination
    • Ramounet B and Fritsch P (1998) The distribution of plutonium between the mineral and organic components of rat bone: a biochemical study after in vivo and in vitro contamination. Int J Radiat Biol 73: 83-88.
    • (1998) Int J Radiat Biol , vol.73 , pp. 83-88
    • Ramounet, B.1    Fritsch, P.2


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