High-throughput sequencing for the identification of binding molecules from DNA-encoded chemical libraries

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 14, 2010, Pages 4188-4192

  Buller, Fabian ^a   Steiner, Martina ^a   Scheuermann, Jörg ^a   Mannocci, Luca ^a   Nissen, Ina ^a   Kohler, Manuel ^a   Beisel, Christian ^a   Neri, Dario ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

454; DNA encoded chemical library; Drug discovery; High throughput sequencing; Illumina

Indexed keywords

DNA;

ARTICLE; COST; DNA DETERMINATION; DNA SEQUENCE; EXPERIMENT; MOLECULAR LIBRARY; TECHNOLOGY;

COMBINATORIAL CHEMISTRY TECHNIQUES; DNA;

EID: 77953870958     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.05.053     Document Type: Article

References (33)

1. Brenner S., and Lerner R.A. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 5381
2. Scheuermann J., Dumelin C.E., Melkko S., and Neri D. J. Biotechnol. 126 (2006) 568
3. Tse B.N., Snyder T.M., Shen Y., and Liu D.R. J. Am. Chem. Soc. 130 (2008) 15611
4. Melkko S., Scheuermann J., Dumelin C.E., and Neri D. Nat. Biotechnol. 22 (2004) 568
5. Mannocci L., Zhang Y., Scheuermann J., Leimbacher M., De Bellis G., Rizzi E., Dumelin C., Melkko S., and Neri D. Proc. Natl. Acad. Sci. U.S.A. 105 (2008) 17670
6. Clark M.A., Acharya R.A., Arico-Muendel C.C., Belyanskaya S.L., Benjamin D.R., Carlson N.R., Centrella P.A., Chiu C.H., Creaser S.P., Cuozzo J.W., Davie C.P., Ding Y., Franklin G.J., Franzen K.D., Gefter M.L., Hale S.P., Hansen N.J., Israel D.I., Jiang J., Kavarana M.J., Kelley M.S., Kollmann C.S., Li F., Lind K., Mataruse S., Medeiros P.F., Messer J.A., Myers P., O'Keefe H., Oliff M.C., Rise C.E., Satz A.L., Skinner S.R., Svendsen J.L., Tang L., van Vloten K., Wagner R.W., Yao G., Zhao B., and Morgan B.A. Nat. Chem. Biol. 5 (2009) 647
7. Buller F., Zhang Y., Scheuermann J., Schafer J., Buhlmann P., and Neri D. Chem. Biol. 16 (2009) 1075
8. Buller F., Mannocci L., Zhang Y., Dumelin C.E., Scheuermann J., and Neri D. Bioorg. Med. Chem. Lett. 18 (2008) 5926
9. Halpin D.R., and Harbury P.B. PLoS Biol. 2 (2004) 1022
10. Wrenn S.J., Weisinger R.M., Halpin D.R., and Harbury P.B. J. Am. Chem. Soc. 129 (2007) 13137
11. Hansen M.H., Blakskjaer P., Petersen L.K., Hansen T.H., Hojfeldt J.W., Gothelf K.V., and Hansen N.J. J. Am. Chem. Soc. 131 (2009) 1322
12. Pellecchia M., Bertini I., Cowburn D., Dalvit C., Giralt E., Jahnke W., James T.L., Homans S.W., Kessler H., Luchinat C., Meyer B., Oschkinat H., Peng J., Schwalbe H., and Siegal G. Nat. Rev. Drug Disc. 7 (2008) 738
13. Keseru G.M., and Makara G.M. Nat. Rev. Drug Disc. 8 (2009) 203
14. Scheuermann J., Dumelin C.E., Melkko S., Zhang Y., Mannocci L., Jaggi M., Sobek J., and Neri D. Bioconjug. Chem. 19 (2008) 778
15. Gartner Z.J., Tse B.N., Grubina R., Doyon J.B., Snyder T.M., and Liu D.R. Science 305 (2004) 1601
16. Dumelin C.E., Trussel S., Buller F., Trachsel E., Bootz F., Zhang Y., Mannocci L., Beck S.C., Drumea-Mirancea M., Seeliger M.W., Baltes C., Muggler T., Kranz F., Rudin M., Melkko S., Scheuermann J., and Neri D. Angew. Chem., Int. Ed. 47 (2008) 3196
17. Melkko S., Zhang Y., Dumelin C.E., Scheuermann J., and Neri D. Angew. Chem., Int. Ed. 46 (2007) 4671
18. Margulies M., Egholm M., Altman W.E., Attiya S., Bader J.S., Bemben L.A., Berka J., Braverman M.S., Chen Y.J., Chen Z., Dewell S.B., Du L., Fierro J.M., Gomes X.V., Godwin B.C., He W., Helgesen S., Ho C.H., Irzyk G.P., Jando S.C., Alenquer M.L., Jarvie T.P., Jirage K.B., Kim J.B., Knight J.R., Lanza J.R., Leamon J.H., Lefkowitz S.M., Lei M., Li J., Lohman K.L., Lu H., Makhijani V.B., McDade K.E., McKenna M.P., Myers E.W., Nickerson E., Nobile J.R., Plant R., Puc B.P., Ronan M.T., Roth G.T., Sarkis G.J., Simons J.F., Simpson J.W., Srinivasan M., Tartaro K.R., Tomasz A., Vogt K.A., Volkmer G.A., Wang S.H., Wang Y., Weiner M.P., Yu P., Begley R.F., and Rothberg J.M. Nature 437 (2005) 376
19. Pettersson E., Lundeberg J., and Ahmadian A. Genomics 93 (2009) 105
20. Bennett S.T., Barnes C., Cox A., Davies L., and Brown C. Pharmacogenomics 6 (2005) 373
21. Bennett S. Pharmacogenomics 5 (2004) 433
22. Morozova O., and Marra M.A. Genomics 92 (2008) 255
23. Adessi C., Matton G., Ayala G., Turcatti G., Mermod J.J., Mayer P., and Kawashima E. Nucleic Acids Res. 28 (2000) E87
24. Dumelin C.E., Scheuermann J., Melkko S., and Neri D. Bioconjug. Chem. 17 (2006) 366
25. Lehar J., Stockwell B.R., Giaever G., and Nislow C. Nat. Chem. Biol. 4 (2008) 674
26. Wells J.A., and McClendon C.L. Nature 450 (2007) 1001
27. Kramer R., and Cohen D. Nat. Rev. Drug Disc. 3 (2004) 965
28. Mayr L.M., and Bojanic D. Curr. Opin. Pharmacol. 9 (2009) 580
29. Winter G., Griffiths A.D., Hawkins R.E., and Hoogenboom H.R. Annu. Rev. Immunol. 12 (1994) 433
30. Fox S., Filichkin S., and Mockler T.C. Methods Mol. Biol. 553 (2009) 79
31. Lipinski C.A. J. Pharmacol. Toxicol. Methods 44 (2000) 235
32. Lipinski C.A., Lombardo F., Dominy B.W., and Feeney P.J. Adv. Drug. Deliv. Rev. 46 (2001) 3
33. Pfaffen S., Hemmerle T., Weber M., and Neri D. Exp. Cell Res. 316 (2009) 836