Inhibition of ATP-induced macrophage death by emodin via antagonizing P2X7 receptor

European Journal of Pharmacology

Volumn 640, Issue 1-3, 2010, Pages 15-19

  Liu, Lijun ^a   Zou, Jie ^a   Liu, Xing ^b   Jiang, Lin Hua ^b   Li, Junying ^a  

^a NANKAI UNIVERSITY   (China)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Antagonist; ATP; Emodin; Macrophage death; P2X7

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; EMODIN; ETHIDIUM BROMIDE; PURINERGIC P2X7 RECEPTOR; 3'-O-(4-BENZOYL)BENZOYLADENOSINE 5'-TRIPHOSPHATE; ANTIINFLAMMATORY AGENT; CALCIUM; ETHIDIUM; IMMUNOSUPPRESSIVE AGENT; P2RX7 PROTEIN, HUMAN; P2RX7 PROTEIN, RAT; PURINERGIC P2 RECEPTOR ANTAGONIST;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL STRAIN HEK293; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IC 50; MOLECULAR CLONING; NONHUMAN; PATCH CLAMP; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECTS; ELECTRIC CONDUCTIVITY; MACROPHAGE; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL; WISTAR RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL TRANSPORT; CALCIUM; CELL DEATH; CELL LINE; ELECTRIC CONDUCTIVITY; EMODIN; ETHIDIUM; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MACROPHAGES; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2; PURINERGIC P2 RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2X7;

EID: 77953809988     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.04.036     Document Type: Article

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