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Volumn 224, Issue 1, 2010, Pages 3-14

The endocannabinoid system and psychiatric disorders

Author keywords

Anxiety; Depression; Endocannabinoid system; Schizophrenia

Indexed keywords

ANANDAMIDE; BRAIN DERIVED NEUROTROPHIC FACTOR; CANNABIDIOL; CANNABINOID 1 RECEPTOR; CHOLECYSTOKININ; CLOZAPINE; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; ENDOCANNABINOID; HALOPERIDOL; RIMONABANT;

EID: 77953707182     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2010.03.018     Document Type: Review
Times cited : (118)

References (128)
  • 1
    • 67649998667 scopus 로고    scopus 로고
    • Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats
    • Aguiar D.C., Terzian A.L., Guimaraes F.S., Moreira F.A. Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats. Psychopharmacology (Berl.) 2009, 205:217-225.
    • (2009) Psychopharmacology (Berl.) , vol.205 , pp. 217-225
    • Aguiar, D.C.1    Terzian, A.L.2    Guimaraes, F.S.3    Moreira, F.A.4
  • 2
    • 0037164390 scopus 로고    scopus 로고
    • Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study
    • Arseneault L., Cannon M., Poulton R., Murray R., Caspi A., Moffitt T.E. Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study. BMJ 2002, 325:1212-1213.
    • (2002) BMJ , vol.325 , pp. 1212-1213
    • Arseneault, L.1    Cannon, M.2    Poulton, R.3    Murray, R.4    Caspi, A.5    Moffitt, T.E.6
  • 3
    • 41749106682 scopus 로고    scopus 로고
    • BDNF impairment in the hippocampus is related to enhanced despair behavior in CB1 knockout mice
    • Aso E., Ozaita A., Valdizan E.M., Ledent C., Pazos A., Maldonado R., Valverde O. BDNF impairment in the hippocampus is related to enhanced despair behavior in CB1 knockout mice. J. Neurochem. 2008, 105:565-572.
    • (2008) J. Neurochem. , vol.105 , pp. 565-572
    • Aso, E.1    Ozaita, A.2    Valdizan, E.M.3    Ledent, C.4    Pazos, A.5    Maldonado, R.6    Valverde, O.7
  • 4
    • 34548666018 scopus 로고    scopus 로고
    • Cannabinoid receptor antagonists counteract sensorimotor gating deficits in the phencyclidine model of psychosis
    • Ballmaier M., Bortolato M., Rizzetti C., Zoli M., Gessa G., Heinz A., Spano P. Cannabinoid receptor antagonists counteract sensorimotor gating deficits in the phencyclidine model of psychosis. Neuropsychopharmacology 2007, 32:2098-2107.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 2098-2107
    • Ballmaier, M.1    Bortolato, M.2    Rizzetti, C.3    Zoli, M.4    Gessa, G.5    Heinz, A.6    Spano, P.7
  • 5
    • 35548980029 scopus 로고    scopus 로고
    • Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex
    • Bambico F.R., Katz N., Debonnel G., Gobbi G. Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex. J. Neurosci. 2007, 27:11700-11711.
    • (2007) J. Neurosci. , vol.27 , pp. 11700-11711
    • Bambico, F.R.1    Katz, N.2    Debonnel, G.3    Gobbi, G.4
  • 6
    • 31444441701 scopus 로고    scopus 로고
    • New approaches to antidepressant drug discovery: beyond monoamines
    • Berton O., Nestler E.J. New approaches to antidepressant drug discovery: beyond monoamines. Nat. Rev. Neurosci. 2006, 7:137-151.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 137-151
    • Berton, O.1    Nestler, E.J.2
  • 8
    • 12344322520 scopus 로고    scopus 로고
    • The CB receptor agonist WIN 55,212-2 fails to elicit disruption of prepulse inhibition of the startle in Sprague-Dawley rats
    • Bortolato M., Aru G.N., Frau R., Orru M., Luckey G.C., Boi G., Gessa G.L. The CB receptor agonist WIN 55,212-2 fails to elicit disruption of prepulse inhibition of the startle in Sprague-Dawley rats. Psychopharmacology (Berl.) 2005, 177:264-271.
    • (2005) Psychopharmacology (Berl.) , vol.177 , pp. 264-271
    • Bortolato, M.1    Aru, G.N.2    Frau, R.3    Orru, M.4    Luckey, G.C.5    Boi, G.6    Gessa, G.L.7
  • 11
    • 20944446077 scopus 로고    scopus 로고
    • Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-o-methyltransferase gene: longitudinal evidence of a gene X environment interaction
    • Caspi A., Moffitt T.E., Cannon M., McClay J., Murray R., Harrington H., et al. Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-o-methyltransferase gene: longitudinal evidence of a gene X environment interaction. Biol. Psychiatry 2005, 57:1117-1127.
    • (2005) Biol. Psychiatry , vol.57 , pp. 1117-1127
    • Caspi, A.1    Moffitt, T.E.2    Cannon, M.3    McClay, J.4    Murray, R.5    Harrington, H.6
  • 14
    • 0035961131 scopus 로고    scopus 로고
    • Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use
    • Dean B., Sundram S., Bradbury R., Scarr E., Copolov D. Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use. Neuroscience 2001, 103:9-15.
    • (2001) Neuroscience , vol.103 , pp. 9-15
    • Dean, B.1    Sundram, S.2    Bradbury, R.3    Scarr, E.4    Copolov, D.5
  • 16
    • 56249124903 scopus 로고    scopus 로고
    • Auditory gating in rat hippocampus and medial prefrontal cortex: effect of the cannabinoid agonist WIN55, 212-2
    • Dissanayake D.W., Zachariou M., Marsden C.A., Mason R. Auditory gating in rat hippocampus and medial prefrontal cortex: effect of the cannabinoid agonist WIN55, 212-2. Neuropharmacology 2008, 55:1397-1404.
    • (2008) Neuropharmacology , vol.55 , pp. 1397-1404
    • Dissanayake, D.W.1    Zachariou, M.2    Marsden, C.A.3    Mason, R.4
  • 18
    • 34250344214 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis as target for the treatment of depression
    • Drew M.R., Hen R. Adult hippocampal neurogenesis as target for the treatment of depression. CNS Neurol. Disord. Drug Targets 2007, 6:205-218.
    • (2007) CNS Neurol. Disord. Drug Targets , vol.6 , pp. 205-218
    • Drew, M.R.1    Hen, R.2
  • 20
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman R.S., Monteggia L.M. A neurotrophic model for stress-related mood disorders. Biol. Psychiatry 2006, 59:1116-1127.
    • (2006) Biol. Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 21
    • 46849111394 scopus 로고    scopus 로고
    • Reduced cortical cannabinoid 1 receptor messenger RNA and protein expression in schizophrenia
    • Eggan S.M., Hashimoto T., Lewis D.A. Reduced cortical cannabinoid 1 receptor messenger RNA and protein expression in schizophrenia. Arch. Gen. Psychiatry 2008, 65:772-784.
    • (2008) Arch. Gen. Psychiatry , vol.65 , pp. 772-784
    • Eggan, S.M.1    Hashimoto, T.2    Lewis, D.A.3
  • 22
    • 0034481144 scopus 로고    scopus 로고
    • Cognitive impairment in schizophrenia is the core of the disorder
    • Elvevag B., Goldberg T.E. Cognitive impairment in schizophrenia is the core of the disorder. Crit. Rev. Neurobiol. 2000, 14:1-21.
    • (2000) Crit. Rev. Neurobiol. , vol.14 , pp. 1-21
    • Elvevag, B.1    Goldberg, T.E.2
  • 24
    • 77953693775 scopus 로고    scopus 로고
    • Endocannabinoid-mediated modulation of stress responses: Physiological and pathophysiological significance
    • (Electronic publication ahead of print)
    • Finn D.P. Endocannabinoid-mediated modulation of stress responses: Physiological and pathophysiological significance. Immunobiology 2009, (Electronic publication ahead of print).
    • (2009) Immunobiology
    • Finn, D.P.1
  • 25
    • 60349127390 scopus 로고    scopus 로고
    • The use of a synthetic cannabinoid in the management of treatment-resistant nightmares in posttraumatic stress disorder (PTSD)
    • Fraser G.A. The use of a synthetic cannabinoid in the management of treatment-resistant nightmares in posttraumatic stress disorder (PTSD). CNS Neurosci. Ther. 2009, 15:84-88.
    • (2009) CNS Neurosci. Ther. , vol.15 , pp. 84-88
    • Fraser, G.A.1
  • 27
    • 0031047273 scopus 로고    scopus 로고
    • Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain
    • Glass M., Dragunow M., Faull R.L. Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain. Neuroscience 1997, 77:299-318.
    • (1997) Neuroscience , vol.77 , pp. 299-318
    • Glass, M.1    Dragunow, M.2    Faull, R.L.3
  • 30
    • 0032587994 scopus 로고    scopus 로고
    • Chronic (-)-delta9-tetrahydrocannabinol treatment induces sensitization to the psychomotor effects of amphetamine in rats
    • Gorriti M.A., Rodriguez de Fonseca F., Navarro M., Palomo T. Chronic (-)-delta9-tetrahydrocannabinol treatment induces sensitization to the psychomotor effects of amphetamine in rats. Eur. J. Pharmacol. 1999, 365:133-142.
    • (1999) Eur. J. Pharmacol. , vol.365 , pp. 133-142
    • Gorriti, M.A.1    Rodriguez de Fonseca, F.2    Navarro, M.3    Palomo, T.4
  • 32
    • 45849113264 scopus 로고    scopus 로고
    • Regulation of endocannabinoid signaling by stress: implications for stress-related affective disorders
    • Gorzalka B.B., Hill M.N., Hillard C.J. Regulation of endocannabinoid signaling by stress: implications for stress-related affective disorders. Neurosci. Biobehav. Rev. 2008, 32:1152-1160.
    • (2008) Neurosci. Biobehav. Rev. , vol.32 , pp. 1152-1160
    • Gorzalka, B.B.1    Hill, M.N.2    Hillard, C.J.3
  • 33
    • 13244253872 scopus 로고    scopus 로고
    • Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents
    • Griebel G., Stemmelin J., Scatton B. Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents. Biol. Psychiatry 2005, 57:261-267.
    • (2005) Biol. Psychiatry , vol.57 , pp. 261-267
    • Griebel, G.1    Stemmelin, J.2    Scatton, B.3
  • 36
    • 43049155942 scopus 로고    scopus 로고
    • Activation of cannabinoid-1 receptors disrupts sensory gating and neuronal oscillation: relevance to schizophrenia
    • Hajos M., Hoffmann W.E., Kocsis B. Activation of cannabinoid-1 receptors disrupts sensory gating and neuronal oscillation: relevance to schizophrenia. Biol. Psychiatry 2008, 63:1075-1083.
    • (2008) Biol. Psychiatry , vol.63 , pp. 1075-1083
    • Hajos, M.1    Hoffmann, W.E.2    Kocsis, B.3
  • 37
    • 4944222090 scopus 로고    scopus 로고
    • Cannabis use and psychotic disorders: an update
    • Hall W., Degenhardt L., Teesson M. Cannabis use and psychotic disorders: an update. Drug Alcohol Rev. 2004, 23:433-443.
    • (2004) Drug Alcohol Rev. , vol.23 , pp. 433-443
    • Hall, W.1    Degenhardt, L.2    Teesson, M.3
  • 38
    • 0036431691 scopus 로고    scopus 로고
    • The effects of genetic and pharmacological blockade of the CB1 cannabinoid receptor on anxiety
    • Haller J., Bakos N., Szirmay M., Ledent C., Freund T.F. The effects of genetic and pharmacological blockade of the CB1 cannabinoid receptor on anxiety. Eur. J. Neurosci. 2002, 16:1395-1398.
    • (2002) Eur. J. Neurosci. , vol.16 , pp. 1395-1398
    • Haller, J.1    Bakos, N.2    Szirmay, M.3    Ledent, C.4    Freund, T.F.5
  • 39
    • 1842633508 scopus 로고    scopus 로고
    • Context-dependent effects of CB1 cannabinoid gene disruption on anxiety-like and social behaviour in mice
    • Haller J., Varga B., Ledent C., Barna I., Freund T.F. Context-dependent effects of CB1 cannabinoid gene disruption on anxiety-like and social behaviour in mice. Eur. J. Neurosci. 2004, 19:1906-1912.
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1906-1912
    • Haller, J.1    Varga, B.2    Ledent, C.3    Barna, I.4    Freund, T.F.5
  • 40
    • 4043145966 scopus 로고    scopus 로고
    • CB1 cannabinoid receptors mediate anxiolytic effects: convergent genetic and pharmacological evidence with CB1-specific agents
    • Haller J., Varga B., Ledent C., Freund T.F. CB1 cannabinoid receptors mediate anxiolytic effects: convergent genetic and pharmacological evidence with CB1-specific agents. Behav. Pharmacol. 2004, 15:299-304.
    • (2004) Behav. Pharmacol. , vol.15 , pp. 299-304
    • Haller, J.1    Varga, B.2    Ledent, C.3    Freund, T.F.4
  • 41
    • 26044456455 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor dependent effects of the NMDA antagonist phencyclidine in the social withdrawal model of schizophrenia
    • Haller J., Szirmai M., Varga B., Ledent C., Freund T.F. Cannabinoid CB1 receptor dependent effects of the NMDA antagonist phencyclidine in the social withdrawal model of schizophrenia. Behav. Pharmacol. 2005, 16:415-422.
    • (2005) Behav. Pharmacol. , vol.16 , pp. 415-422
    • Haller, J.1    Szirmai, M.2    Varga, B.3    Ledent, C.4    Freund, T.F.5
  • 42
    • 67349253906 scopus 로고    scopus 로고
    • Interactions between environmental aversiveness and the anxiolytic effects of enhanced cannabinoid signaling by FAAH inhibition in rats
    • Haller J., Barna I., Barsvari B., Gyimesi Pelczer K., Yasar S., Panlilio L.V., Goldberg S. Interactions between environmental aversiveness and the anxiolytic effects of enhanced cannabinoid signaling by FAAH inhibition in rats. Psychopharmacology (Berl.) 2009, 204:607-616.
    • (2009) Psychopharmacology (Berl.) , vol.204 , pp. 607-616
    • Haller, J.1    Barna, I.2    Barsvari, B.3    Gyimesi Pelczer, K.4    Yasar, S.5    Panlilio, L.V.6    Goldberg, S.7
  • 44
    • 24344470642 scopus 로고    scopus 로고
    • The environment and schizophrenia: the role of cannabis use
    • Henquet C., Murray R., Linszen D., van Os J. The environment and schizophrenia: the role of cannabis use. Schizophr. Bull. 2005, 31:608-612.
    • (2005) Schizophr. Bull. , vol.31 , pp. 608-612
    • Henquet, C.1    Murray, R.2    Linszen, D.3    van Os, J.4
  • 45
    • 33751119258 scopus 로고    scopus 로고
    • An experimental study of catechol-o-methyltransferase Val158Met moderation of delta-9-tetrahydrocannabinol-induced effects on psychosis and cognition
    • Henquet C., Rosa A., Krabbendam L., Papiol S., Fananas L., Drukker M., et al. An experimental study of catechol-o-methyltransferase Val158Met moderation of delta-9-tetrahydrocannabinol-induced effects on psychosis and cognition. Neuropsychopharmacology 2006, 31:2748-2757.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2748-2757
    • Henquet, C.1    Rosa, A.2    Krabbendam, L.3    Papiol, S.4    Fananas, L.5    Drukker, M.6
  • 46
    • 67349150691 scopus 로고    scopus 로고
    • The association between early cannabis use and psychotic-like experiences in a community adolescent sample
    • Hides L., Lubman D.I., Buckby J., Yuen H.P., Cosgrave E., Baker K., et al. The association between early cannabis use and psychotic-like experiences in a community adolescent sample. Schizophr. Res. 2009, 112:130-135.
    • (2009) Schizophr. Res. , vol.112 , pp. 130-135
    • Hides, L.1    Lubman, D.I.2    Buckby, J.3    Yuen, H.P.4    Cosgrave, E.5    Baker, K.6
  • 47
    • 26044433145 scopus 로고    scopus 로고
    • Is there a role for the endocannabinoid system in the etiology and treatment of melancholic depression?
    • Hill M.N., Gorzalka B.B. Is there a role for the endocannabinoid system in the etiology and treatment of melancholic depression?. Behav. Pharmacol. 2005, 16:333-352.
    • (2005) Behav. Pharmacol. , vol.16 , pp. 333-352
    • Hill, M.N.1    Gorzalka, B.B.2
  • 48
    • 26044436133 scopus 로고    scopus 로고
    • Pharmacological enhancement of cannabinoid CB1 receptor activity elicits an antidepressant-like response in the rat forced swim test
    • Hill M.N., Gorzalka B.B. Pharmacological enhancement of cannabinoid CB1 receptor activity elicits an antidepressant-like response in the rat forced swim test. Eur. Neuropsychopharmacol. 2005, 15:593-599.
    • (2005) Eur. Neuropsychopharmacol. , vol.15 , pp. 593-599
    • Hill, M.N.1    Gorzalka, B.B.2
  • 49
    • 75849127602 scopus 로고    scopus 로고
    • The endocannabinoid system and the treatment of mood and anxiety disorders
    • Hill M.N., Gorzalka B.B. The endocannabinoid system and the treatment of mood and anxiety disorders. CNS Neurol. Disord. Drug Targets 2009, 8:451-458.
    • (2009) CNS Neurol. Disord. Drug Targets , vol.8 , pp. 451-458
    • Hill, M.N.1    Gorzalka, B.B.2
  • 51
    • 33750060283 scopus 로고    scopus 로고
    • Endocannabinoids modulate stress-induced suppression of hippocampal cell proliferation and activation of defensive behaviours
    • Hill M.N., Kambo J.S., Sun J.C., Gorzalka B.B., Galea L.A. Endocannabinoids modulate stress-induced suppression of hippocampal cell proliferation and activation of defensive behaviours. Eur. J. Neurosci. 2006, 24:1845-1849.
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 1845-1849
    • Hill, M.N.1    Kambo, J.S.2    Sun, J.C.3    Gorzalka, B.B.4    Galea, L.A.5
  • 52
    • 50849142856 scopus 로고    scopus 로고
    • Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment
    • Hill M.N., Carrier E.J., McLaughlin R.J., Morrish A.C., Meier S.E., Hillard C.J., Gorzalka B.B. Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment. J. Neurochem. 2008, 106:2322-2336.
    • (2008) J. Neurochem. , vol.106 , pp. 2322-2336
    • Hill, M.N.1    Carrier, E.J.2    McLaughlin, R.J.3    Morrish, A.C.4    Meier, S.E.5    Hillard, C.J.6    Gorzalka, B.B.7
  • 53
    • 67650617724 scopus 로고    scopus 로고
    • Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress
    • Hill M.N., Miller G.E., Carrier E.J., Gorzalka B.B., Hillard C.J. Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. Psychoneuroendocrinology 2009, 34:1257-1262.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. 1257-1262
    • Hill, M.N.1    Miller, G.E.2    Carrier, E.J.3    Gorzalka, B.B.4    Hillard, C.J.5
  • 54
    • 12344282798 scopus 로고    scopus 로고
    • CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors
    • Houchi H., Babovic D., Pierrefiche O., Ledent C., Daoust M., Naassila M. CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors. Neuropsychopharmacology 2005, 30:339-349.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 339-349
    • Houchi, H.1    Babovic, D.2    Pierrefiche, O.3    Ledent, C.4    Daoust, M.5    Naassila, M.6
  • 56
    • 27644433182 scopus 로고    scopus 로고
    • Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects
    • Jiang W., Zhang Y., Xiao L., Van Cleemput J., Ji S.P., Bai G., Zhang X. Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects. J. Clin. Invest. 2005, 115:3104-3116.
    • (2005) J. Clin. Invest. , vol.115 , pp. 3104-3116
    • Jiang, W.1    Zhang, Y.2    Xiao, L.3    Van Cleemput, J.4    Ji, S.P.5    Bai, G.6    Zhang, X.7
  • 58
    • 34447098652 scopus 로고    scopus 로고
    • Expression of CB1 cannabinoid receptor in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression
    • Koethe D., Llenos I.C., Dulay J.R., Hoyer C., Torrey E.F., Leweke F.M., Weis S. Expression of CB1 cannabinoid receptor in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression. J. Neural Transm. 2007, 114:1055-1063.
    • (2007) J. Neural Transm. , vol.114 , pp. 1055-1063
    • Koethe, D.1    Llenos, I.C.2    Dulay, J.R.3    Hoyer, C.4    Torrey, E.F.5    Leweke, F.M.6    Weis, S.7
  • 59
    • 35649020711 scopus 로고    scopus 로고
    • The endocannabinoid system in the processing of anxiety and fear and how CB1 receptors may modulate fear extinction
    • Lafenetre P., Chaouloff F., Marsicano G. The endocannabinoid system in the processing of anxiety and fear and how CB1 receptors may modulate fear extinction. Pharmacol. Res. 2007, 56:367-381.
    • (2007) Pharmacol. Res. , vol.56 , pp. 367-381
    • Lafenetre, P.1    Chaouloff, F.2    Marsicano, G.3
  • 61
    • 54249154003 scopus 로고    scopus 로고
    • Double blind, controlled clinical trial of cannabidiol monotherapy versus amisulpiride in the treatment of acutely psychotic schizophrenia patients
    • Leweke F., Koethe D., Gerth C.W., et al. Double blind, controlled clinical trial of cannabidiol monotherapy versus amisulpiride in the treatment of acutely psychotic schizophrenia patients. Schizophr. Bull. 2007, 33:310.
    • (2007) Schizophr. Bull. , vol.33 , pp. 310
    • Leweke, F.1    Koethe, D.2    Gerth, C.W.3
  • 63
    • 33645029075 scopus 로고    scopus 로고
    • Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice
    • Long L.E., Malone D.T., Taylor D.A. Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice. Neuropsychopharmacology 2006, 31:795-803.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 795-803
    • Long, L.E.1    Malone, D.T.2    Taylor, D.A.3
  • 64
    • 4744351585 scopus 로고    scopus 로고
    • Marijuana and cannabinoid regulation of brain reward circuits
    • Lupica C.R., Riegel A.C., Hoffman A.F. Marijuana and cannabinoid regulation of brain reward circuits. Br. J. Pharmacol. 2004, 143:227-234.
    • (2004) Br. J. Pharmacol. , vol.143 , pp. 227-234
    • Lupica, C.R.1    Riegel, A.C.2    Hoffman, A.F.3
  • 65
    • 38449115285 scopus 로고    scopus 로고
    • The endocannabinoid system and extinction learning
    • Lutz B. The endocannabinoid system and extinction learning. Mol. Neurobiol. 2007, 36:92-101.
    • (2007) Mol. Neurobiol. , vol.36 , pp. 92-101
    • Lutz, B.1
  • 66
    • 63249087708 scopus 로고    scopus 로고
    • What is the mechanism whereby cannabis use increases risk of psychosis?
    • Luzi S., Morrison P.D., Powell J., di Forti M., Murray R.M. What is the mechanism whereby cannabis use increases risk of psychosis?. Neurotox. Res. 2008, 14:105-112.
    • (2008) Neurotox. Res. , vol.14 , pp. 105-112
    • Luzi, S.1    Morrison, P.D.2    Powell, J.3    di Forti, M.4    Murray, R.M.5
  • 68
    • 33748145215 scopus 로고    scopus 로고
    • Effects of the cannabinoid CB1 receptor agonist CP55, 940 and antagonist SR141716A on d-amphetamine-induced behaviours in Cebus monkeys
    • Madsen M.V., Peacock L., Werge T., Andersen M.B. Effects of the cannabinoid CB1 receptor agonist CP55, 940 and antagonist SR141716A on d-amphetamine-induced behaviours in Cebus monkeys. J. Psychopharmacol. 2006, 20:622-628.
    • (2006) J. Psychopharmacol. , vol.20 , pp. 622-628
    • Madsen, M.V.1    Peacock, L.2    Werge, T.3    Andersen, M.B.4
  • 69
    • 27944484447 scopus 로고    scopus 로고
    • The effect of Delta9-tetrahydrocannabinol on sensorimotor gating in socially isolated rats
    • Malone D.T., Taylor D.A. The effect of Delta9-tetrahydrocannabinol on sensorimotor gating in socially isolated rats. Behav. Brain Res. 2006, 166:101-109.
    • (2006) Behav. Brain Res. , vol.166 , pp. 101-109
    • Malone, D.T.1    Taylor, D.A.2
  • 70
    • 1942455357 scopus 로고    scopus 로고
    • The effect of SR 141716 and apomorphine on sensorimotor gating in Swiss mice
    • Malone D.T., Long L.E., Taylor D.A. The effect of SR 141716 and apomorphine on sensorimotor gating in Swiss mice. Pharmacol. Biochem. Behav. 2004, 77:839-845.
    • (2004) Pharmacol. Biochem. Behav. , vol.77 , pp. 839-845
    • Malone, D.T.1    Long, L.E.2    Taylor, D.A.3
  • 71
    • 39649120778 scopus 로고    scopus 로고
    • Effect of social isolation on CB1 and D2 receptor and fatty acid amide hydrolase expression in rats
    • Malone D.T., Kearn C.S., Chongue L., Mackie K., Taylor D.A. Effect of social isolation on CB1 and D2 receptor and fatty acid amide hydrolase expression in rats. Neuroscience 2008, 152:265-272.
    • (2008) Neuroscience , vol.152 , pp. 265-272
    • Malone, D.T.1    Kearn, C.S.2    Chongue, L.3    Mackie, K.4    Taylor, D.A.5
  • 72
    • 0029933318 scopus 로고    scopus 로고
    • Effects of the cannabinoid CB1 receptor antagonist SR141716A on the behavior of pigeons and rats
    • Mansbach R.S., Rovetti C.C., Winston E.N., Lowe J.A. Effects of the cannabinoid CB1 receptor antagonist SR141716A on the behavior of pigeons and rats. Psychopharmacology (Berl.) 1996, 124:315-322.
    • (1996) Psychopharmacology (Berl.) , vol.124 , pp. 315-322
    • Mansbach, R.S.1    Rovetti, C.C.2    Winston, E.N.3    Lowe, J.A.4
  • 79
    • 34548389394 scopus 로고    scopus 로고
    • Local enhancement of cannabinoid CB1 receptor signalling in the dorsal hippocampus elicits an antidepressant-like effect
    • McLaughlin R.J., Hill M.N., Morrish A.C., Gorzalka B.B. Local enhancement of cannabinoid CB1 receptor signalling in the dorsal hippocampus elicits an antidepressant-like effect. Behav. Pharmacol. 2007, 18:431-438.
    • (2007) Behav. Pharmacol. , vol.18 , pp. 431-438
    • McLaughlin, R.J.1    Hill, M.N.2    Morrish, A.C.3    Gorzalka, B.B.4
  • 80
    • 2942538034 scopus 로고    scopus 로고
    • Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder
    • Meltzer H.Y., Arvanitis L., Bauer D., Rein W. Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder. Am. J. Psychiatry 2004, 161:975-984.
    • (2004) Am. J. Psychiatry , vol.161 , pp. 975-984
    • Meltzer, H.Y.1    Arvanitis, L.2    Bauer, D.3    Rein, W.4
  • 81
    • 58149461157 scopus 로고    scopus 로고
    • Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels
    • Micale V., Cristino L., Tamburella A., Petrosino S., Leggio G.M., Drago F., Di Marzo V. Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels. Neuropsychopharmacology 2009, 34:593-606.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 593-606
    • Micale, V.1    Cristino, L.2    Tamburella, A.3    Petrosino, S.4    Leggio, G.M.5    Drago, F.6    Di Marzo, V.7
  • 82
    • 34447619511 scopus 로고    scopus 로고
    • Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
    • Moore T.H., Zammit S., Lingford-Hughes A., Barnes T.R., Jones P.B., Burke M., Lewis G. Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet 2007, 370:319-328.
    • (2007) Lancet , vol.370 , pp. 319-328
    • Moore, T.H.1    Zammit, S.2    Lingford-Hughes, A.3    Barnes, T.R.4    Jones, P.B.5    Burke, M.6    Lewis, G.7
  • 83
    • 17444393586 scopus 로고    scopus 로고
    • Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice
    • Moreira F.A., Guimarães F.S. Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice. Eur. J. Pharmacol. 2005, 512:199-205.
    • (2005) Eur. J. Pharmacol. , vol.512 , pp. 199-205
    • Moreira, F.A.1    Guimarães, F.S.2
  • 85
    • 67649482339 scopus 로고    scopus 로고
    • Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: role of gender and noradrenergic transmission
    • Morrish A.C., Hill M.N., Riebe C.J., Gorzalka B.B. Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: role of gender and noradrenergic transmission. Physiol. Behav. 2009, 98:118-124.
    • (2009) Physiol. Behav. , vol.98 , pp. 118-124
    • Morrish, A.C.1    Hill, M.N.2    Riebe, C.J.3    Gorzalka, B.B.4
  • 87
    • 33745623410 scopus 로고    scopus 로고
    • Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia
    • Newell K.A., Deng C., Huang X.F. Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia. Exp. Brain Res. 2006, 172:556-560.
    • (2006) Exp. Brain Res. , vol.172 , pp. 556-560
    • Newell, K.A.1    Deng, C.2    Huang, X.F.3
  • 89
    • 20144378367 scopus 로고    scopus 로고
    • Systemic administration of WIN 55, 212-2 increases norepinephrine release in the rat frontal cortex
    • Oropeza V.C., Page M.E., Van Bockstaele E.J. Systemic administration of WIN 55, 212-2 increases norepinephrine release in the rat frontal cortex. Brain Res. 2005, 1046:45-54.
    • (2005) Brain Res. , vol.1046 , pp. 45-54
    • Oropeza, V.C.1    Page, M.E.2    Van Bockstaele, E.J.3
  • 90
    • 9444277292 scopus 로고    scopus 로고
    • Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis
    • Patel S., Roelke C.T., Rademacher D.J., Cullinan W.E., Hillard C.J. Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis. Endocrinology 2004, 145:5431-5438.
    • (2004) Endocrinology , vol.145 , pp. 5431-5438
    • Patel, S.1    Roelke, C.T.2    Rademacher, D.J.3    Cullinan, W.E.4    Hillard, C.J.5
  • 91
    • 47549107048 scopus 로고    scopus 로고
    • Cognitive role of neurogenesis in depression and antidepressant treatment
    • Perera T.D., Park S., Nemirovskaya Y. Cognitive role of neurogenesis in depression and antidepressant treatment. Neuroscientist 2008, 14:326-338.
    • (2008) Neuroscientist , vol.14 , pp. 326-338
    • Perera, T.D.1    Park, S.2    Nemirovskaya, Y.3
  • 92
    • 0242268553 scopus 로고    scopus 로고
    • The molecular logic of endocannabinoid signalling
    • Piomelli D. The molecular logic of endocannabinoid signalling. Nat. Rev. Neurosci. 2003, 4:873-884.
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 873-884
    • Piomelli, D.1
  • 93
    • 0033059089 scopus 로고    scopus 로고
    • Blockade of cannabinoid (CB1) receptors by 141716 selectively antagonizes drug-induced reinstatement of exploratory behaviour in gerbils
    • Poncelet M., Barnouin M.C., Breliere J.C., Le Fur G., Soubrie P. Blockade of cannabinoid (CB1) receptors by 141716 selectively antagonizes drug-induced reinstatement of exploratory behaviour in gerbils. Psychopharmacology (Berl.) 1999, 144:144-150.
    • (1999) Psychopharmacology (Berl.) , vol.144 , pp. 144-150
    • Poncelet, M.1    Barnouin, M.C.2    Breliere, J.C.3    Le Fur, G.4    Soubrie, P.5
  • 94
    • 21344470462 scopus 로고    scopus 로고
    • WIN 55, 212-2-induced reduction of cocaine hyperlocomotion: possible inhibition of 5-HT(3) receptor function
    • Przegalinski E., Gothert M., Frankowska M., Filip M. WIN 55, 212-2-induced reduction of cocaine hyperlocomotion: possible inhibition of 5-HT(3) receptor function. Eur. J. Pharmacol. 2005, 517:68-73.
    • (2005) Eur. J. Pharmacol. , vol.517 , pp. 68-73
    • Przegalinski, E.1    Gothert, M.2    Frankowska, M.3    Filip, M.4
  • 95
    • 67649643797 scopus 로고    scopus 로고
    • Differential effects of chronic unpredictable stress on hippocampal CB1 receptors in male and female rats
    • Reich C.G., Taylor M.E., McCarthy M.M. Differential effects of chronic unpredictable stress on hippocampal CB1 receptors in male and female rats. Behav. Brain Res. 2009, 203:264-269.
    • (2009) Behav. Brain Res. , vol.203 , pp. 264-269
    • Reich, C.G.1    Taylor, M.E.2    McCarthy, M.M.3
  • 96
    • 61349092930 scopus 로고    scopus 로고
    • Altered CB receptor-signaling in prefrontal cortex from an animal model of depression is reversed by chronic fluoxetine
    • Rodriguez-Gaztelumendi A., Rojo M.L., Pazos A., Diaz A. Altered CB receptor-signaling in prefrontal cortex from an animal model of depression is reversed by chronic fluoxetine. J. Neurochem. 2009, 108:1423-1433.
    • (2009) J. Neurochem. , vol.108 , pp. 1423-1433
    • Rodriguez-Gaztelumendi, A.1    Rojo, M.L.2    Pazos, A.3    Diaz, A.4
  • 97
    • 33846429160 scopus 로고    scopus 로고
    • Role of dorsal hippocampal cannabinoid receptors and nitric oxide in anxiety like behaviours in rats using the elevated plus-maze test
    • Roohbakhsh A., Moghaddam A.H., Massoudi R., Zarrindast M.R. Role of dorsal hippocampal cannabinoid receptors and nitric oxide in anxiety like behaviours in rats using the elevated plus-maze test. Clin. Exp. Pharmacol. Physiol. 2007, 34:223-229.
    • (2007) Clin. Exp. Pharmacol. Physiol. , vol.34 , pp. 223-229
    • Roohbakhsh, A.1    Moghaddam, A.H.2    Massoudi, R.3    Zarrindast, M.R.4
  • 99
    • 0033990498 scopus 로고    scopus 로고
    • In vivo characterization of the specific cannabinoid receptor antagonist, SR141716A: behavioral and cellular responses after acute and chronic treatments
    • Rubino T., Vigano D., Zagato E., Sala M., Parolaro D. In vivo characterization of the specific cannabinoid receptor antagonist, SR141716A: behavioral and cellular responses after acute and chronic treatments. Synapse 2000, 35:8-14.
    • (2000) Synapse , vol.35 , pp. 8-14
    • Rubino, T.1    Vigano, D.2    Zagato, E.3    Sala, M.4    Parolaro, D.5
  • 100
    • 33747838016 scopus 로고    scopus 로고
    • Changes in the expression of G protein-coupled receptor kinases and beta-arrestins in mouse brain during cannabinoid tolerance: a role for RAS-ERK cascade
    • Rubino T., Viganò D., Premoli F., Castiglioni C., Bianchessi S., Zippel R., Parolaro D. Changes in the expression of G protein-coupled receptor kinases and beta-arrestins in mouse brain during cannabinoid tolerance: a role for RAS-ERK cascade. Mol. Neurobiol. 2006, 33:199-213.
    • (2006) Mol. Neurobiol. , vol.33 , pp. 199-213
    • Rubino, T.1    Viganò, D.2    Premoli, F.3    Castiglioni, C.4    Bianchessi, S.5    Zippel, R.6    Parolaro, D.7
  • 104
    • 70449524654 scopus 로고    scopus 로고
    • The depressive phenotype induced in adult female rats by adolescent exposure to THC is associated with cognitive impairment and altered neuroplasticity in the prefrontal cortex
    • Rubino T., Realini N., Braida D., Alberio T., Capurro V., Vigano D., Guidali C., Sala M., Fasano M., Parolaro D. The depressive phenotype induced in adult female rats by adolescent exposure to THC is associated with cognitive impairment and altered neuroplasticity in the prefrontal cortex. Neurotox. Res. 2009, 15:291-302.
    • (2009) Neurotox. Res. , vol.15 , pp. 291-302
    • Rubino, T.1    Realini, N.2    Braida, D.3    Alberio, T.4    Capurro, V.5    Vigano, D.6    Guidali, C.7    Sala, M.8    Fasano, M.9    Parolaro, D.10
  • 106
    • 0036180943 scopus 로고    scopus 로고
    • The cannabinoid agonist WIN 55, 212-2 reduces sensorimotor gating and recognition memory in rats
    • Schneider M., Koch M. The cannabinoid agonist WIN 55, 212-2 reduces sensorimotor gating and recognition memory in rats. Behav. Pharmacol. 2002, 13:29-37.
    • (2002) Behav. Pharmacol. , vol.13 , pp. 29-37
    • Schneider, M.1    Koch, M.2
  • 107
  • 108
    • 77953545992 scopus 로고    scopus 로고
    • Inhibition of fatty-acid amide hydrolase and CB1 receptor antagonism differentially affect behavioural responses in normal and PCP-treated rats
    • Seillier A., Advani T., Cassano T., Hensler J.G., Giuffrida A. Inhibition of fatty-acid amide hydrolase and CB1 receptor antagonism differentially affect behavioural responses in normal and PCP-treated rats. Int. J. Neuropsychopharmacol. 2009, 1-14.
    • (2009) Int. J. Neuropsychopharmacol. , pp. 1-14
    • Seillier, A.1    Advani, T.2    Cassano, T.3    Hensler, J.G.4    Giuffrida, A.5
  • 109
    • 0036955771 scopus 로고    scopus 로고
    • Selective prefrontal cortex inputs to dopamine cells: implications for schizophrenia
    • Sesack S.R., Carr D.B. Selective prefrontal cortex inputs to dopamine cells: implications for schizophrenia. Physiol. Behav. 2002, 77:513-517.
    • (2002) Physiol. Behav. , vol.77 , pp. 513-517
    • Sesack, S.R.1    Carr, D.B.2
  • 110
    • 0024999460 scopus 로고
    • In the rat medial nucleus accumbens, hippocampal and catecholaminergic terminals converge on spiny neurons and are in apposition to each other
    • Sesack S.R., Pickel V.M. In the rat medial nucleus accumbens, hippocampal and catecholaminergic terminals converge on spiny neurons and are in apposition to each other. Brain Res. 1990, 527:266-279.
    • (1990) Brain Res. , vol.527 , pp. 266-279
    • Sesack, S.R.1    Pickel, V.M.2
  • 112
    • 2442507023 scopus 로고    scopus 로고
    • Antidepressant-like and anorectic effects of the cannabinoid CB1 receptor inverse agonist AM251 in mice
    • Shearman L.P., Rosko K.M., Fleischer R., Wang J., Xu S., Tong X.S., Rocha B.A. Antidepressant-like and anorectic effects of the cannabinoid CB1 receptor inverse agonist AM251 in mice. Behav. Pharmacol. 2003, 14:573-582.
    • (2003) Behav. Pharmacol. , vol.14 , pp. 573-582
    • Shearman, L.P.1    Rosko, K.M.2    Fleischer, R.3    Wang, J.4    Xu, S.5    Tong, X.S.6    Rocha, B.A.7
  • 114
    • 71549147546 scopus 로고    scopus 로고
    • Cannabinoid self-administration attenuates PCP-induced schizophrenia-like symptoms in adult rats
    • Spano M.S., Fadda P., Frau R., Fattore L., Fratta W. Cannabinoid self-administration attenuates PCP-induced schizophrenia-like symptoms in adult rats. Eur. Neuropsychopharmacol. 2010, 20:25-36.
    • (2010) Eur. Neuropsychopharmacol. , vol.20 , pp. 25-36
    • Spano, M.S.1    Fadda, P.2    Frau, R.3    Fattore, L.4    Fratta, W.5
  • 115
  • 116
    • 37549022284 scopus 로고    scopus 로고
    • Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice
    • Steiner M.A., Marsicano G., Nestler E.J., Holsboer F., Lutz B., Wotjak C.T. Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice. Psychoneuroendocrinology 2008, 33:54-67.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 54-67
    • Steiner, M.A.1    Marsicano, G.2    Nestler, E.J.3    Holsboer, F.4    Lutz, B.5    Wotjak, C.T.6
  • 118
    • 47549085721 scopus 로고    scopus 로고
    • Additive subthreshold dose effects of cannabinoid CB(1) receptor antagonist and selective serotonin reuptake inhibitor in antidepressant behavioral tests
    • Takahashi E., Katayama M., Niimi K., Itakura C. Additive subthreshold dose effects of cannabinoid CB(1) receptor antagonist and selective serotonin reuptake inhibitor in antidepressant behavioral tests. Eur. J. Pharmacol. 2008, 589:149-156.
    • (2008) Eur. J. Pharmacol. , vol.589 , pp. 149-156
    • Takahashi, E.1    Katayama, M.2    Niimi, K.3    Itakura, C.4
  • 119
    • 58949098416 scopus 로고    scopus 로고
    • Modulation of anxiety-like behaviour by Transient Receptor Potential Vanilloid Type 1 (TRPV1) channels located in the dorsolateral periaqueductal gray
    • Terzian A.L., Aguiar D.C., Guimaraes F.S., Moreira F.A. Modulation of anxiety-like behaviour by Transient Receptor Potential Vanilloid Type 1 (TRPV1) channels located in the dorsolateral periaqueductal gray. Eur. Neuropsychopharmacol. 2009, 19:188-195.
    • (2009) Eur. Neuropsychopharmacol. , vol.19 , pp. 188-195
    • Terzian, A.L.1    Aguiar, D.C.2    Guimaraes, F.S.3    Moreira, F.A.4
  • 120
    • 0037294538 scopus 로고    scopus 로고
    • The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions
    • Tzavara E.T., Davis R.J., Perry K.W., Li X., Salhoff C., Bymaster F.P., Witkin J.M., Nomikos G.G. The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions. Br. J. Pharmacol. 2003, 138:544-553.
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 544-553
    • Tzavara, E.T.1    Davis, R.J.2    Perry, K.W.3    Li, X.4    Salhoff, C.5    Bymaster, F.P.6    Witkin, J.M.7    Nomikos, G.G.8
  • 121
    • 1842664350 scopus 로고    scopus 로고
    • Impaired action of anxiolytic drugs in mice deficient in cannabinoid CB1 receptors
    • Uriguen L., Perez-Rial S., Ledent C., Palomo T., Manzanares J. Impaired action of anxiolytic drugs in mice deficient in cannabinoid CB1 receptors. Neuropharmacology 2004, 46:966-973.
    • (2004) Neuropharmacology , vol.46 , pp. 966-973
    • Uriguen, L.1    Perez-Rial, S.2    Ledent, C.3    Palomo, T.4    Manzanares, J.5
  • 123
    • 44249087350 scopus 로고    scopus 로고
    • Effects of acute systemic and intra-cerebral stimulation of cannabinoid receptors on sensorimotor gating, locomotion and spatial memory in rats
    • Wegener N., Kuhnert S., Thuns A., Roese R., Koch M. Effects of acute systemic and intra-cerebral stimulation of cannabinoid receptors on sensorimotor gating, locomotion and spatial memory in rats. Psychopharmacology (Berl.) 2008, 198:375-385.
    • (2008) Psychopharmacology (Berl.) , vol.198 , pp. 375-385
    • Wegener, N.1    Kuhnert, S.2    Thuns, A.3    Roese, R.4    Koch, M.5
  • 124
    • 0037164374 scopus 로고    scopus 로고
    • Self reported cannabis use as a risk factor for schizophrenia in Swedish conscripts of 1969: historical cohort study
    • Zammit S., Allebeck P., Andreasson S., Lundberg I., Lewis G. Self reported cannabis use as a risk factor for schizophrenia in Swedish conscripts of 1969: historical cohort study. BMJ 2002, 325:1199.
    • (2002) BMJ , vol.325 , pp. 1199
    • Zammit, S.1    Allebeck, P.2    Andreasson, S.3    Lundberg, I.4    Lewis, G.5
  • 125
    • 1642523101 scopus 로고    scopus 로고
    • Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia
    • Zavitsanou K., Garrick T., Huang X.F. Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 2004, 28:355-360.
    • (2004) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.28 , pp. 355-360
    • Zavitsanou, K.1    Garrick, T.2    Huang, X.F.3
  • 126
    • 0025876938 scopus 로고
    • Effects of cannabidiol in animal models predictive of antipsychotic activity
    • Zuardi A.W., Rodrigues J.A., Cunha J.M. Effects of cannabidiol in animal models predictive of antipsychotic activity. Psychopharmacology (Berl.) 1991, 104:260-264.
    • (1991) Psychopharmacology (Berl.) , vol.104 , pp. 260-264
    • Zuardi, A.W.1    Rodrigues, J.A.2    Cunha, J.M.3


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