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Volumn 9, Issue 5, 2010, Pages 389-396

Estrogen receptor-α-interacting cytokeratins potentiate the antiestrogenic activity of fulvestrant

Author keywords

Antiestrogen; Breast cancer; Cytokeratin; Estrogen receptor; Fulvestrant; Tamoxifen

Indexed keywords

CYTOKERATIN 18; CYTOKERATIN 8; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT;

EID: 77953706542     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.9.5.10926     Document Type: Article
Times cited : (9)

References (43)
  • 1
    • 0033753609 scopus 로고    scopus 로고
    • An oestrogen receptor downregulator
    • Howell A. Faslodex. An oestrogen receptor downregulator. Eur J Cancer 2000; 36:87-8.
    • (2000) Eur J Cancer , vol.36 , pp. 87-88
    • Faslodex, H.A.1
  • 2
    • 12144262323 scopus 로고    scopus 로고
    • The molecular pharmacology of estrogen receptor modulators: Implications for the treatment of breast cancer
    • McDonnell DP. The molecular pharmacology of estrogen receptor modulators: implications for the treatment of breast cancer. Clin Cancer Res 2005; 11:871-7.
    • (2005) Clin Cancer Res , vol.11 , pp. 871-877
    • McDonnell, D.P.1
  • 3
    • 0023093455 scopus 로고
    • Steroidal pure antioestrogens
    • Wakeling AE, Bowler J. Steroidal pure antioestrogens. J Endocrinol 1987; 112:7-10.
    • (1987) J Endocrinol , vol.112 , pp. 7-10
    • Wakeling, A.E.1    Bowler, J.2
  • 4
    • 0025084510 scopus 로고
    • Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization
    • Fawell SE, White R, Hoare S, Sydenham M, Page M, Parker MG. Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization. Proc Nat Acad Sci USA 1990; 87:6883-7.
    • (1990) Proc Nat Acad Sci USA , vol.87 , pp. 6883-6887
    • Fawell, S.E.1    White, R.2    Hoare, S.3    Sydenham, M.4    Page, M.5    Parker, M.G.6
  • 5
    • 0026560435 scopus 로고
    • Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover
    • Dauvois S, Danielian PS, White R, Parker MG. Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover. Proc Nat Acad Sci USA 1992; 89:4037-41.
    • (1992) Proc Nat Acad Sci USA , vol.89 , pp. 4037-4041
    • Dauvois, S.1    Danielian, P.S.2    White, R.3    Parker, M.G.4
  • 6
    • 0026701699 scopus 로고
    • ICI 182,780, a new antioestrogen with clinical potential
    • Wakeling AE, Bowler J. ICI 182,780, a new antioestrogen with clinical potential. J Steroid Biochem Mol Biol 1992; 43:173-7.
    • (1992) J Steroid Biochem Mol Biol , vol.43 , pp. 173-177
    • Wakeling, A.E.1    Bowler, J.2
  • 7
    • 35148869577 scopus 로고    scopus 로고
    • Definition of functionally important mechanistic differences among selective estrogen receptor downregulators
    • Wittmann BM, Sherk A, McDonnell DP. Definition of functionally important mechanistic differences among selective estrogen receptor downregulators. Cancer Res 2007; 67:9549-60.
    • (2007) Cancer Res , vol.67 , pp. 9549-9560
    • Wittmann, B.M.1    Sherk, A.2    McDonnell, D.P.3
  • 8
    • 0033855713 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators: Structure, function and clinical use
    • Osborne CK, Zhao H, Fuqua SA. Selective estrogen receptor modulators: structure, function and clinical use. J Clin Oncol 2000; 18:3172-86.
    • (2000) J Clin Oncol , vol.18 , pp. 3172-3186
    • Osborne, C.K.1    Zhao, H.2    Fuqua, S.A.3
  • 9
    • 2942679176 scopus 로고    scopus 로고
    • Tamoxifen: Dr. Jekyll and Mr. Hyde?
    • Hayes DF. Tamoxifen: Dr. Jekyll and Mr. Hyde? J Nat Cancer Inst 2004; 96:895-7.
    • (2004) J Nat Cancer Inst , vol.96 , pp. 895-897
    • Hayes, D.F.1
  • 11
  • 12
    • 33646930743 scopus 로고    scopus 로고
    • Fulvestrant (ICI 182,780)-dependent interacting proteins mediate immobilization and degradation of estrogen receptor-alpha
    • Long X, Nephew KP. Fulvestrant (ICI 182,780)-dependent interacting proteins mediate immobilization and degradation of estrogen receptor-alpha. J Biol Chem 2006; 281:9607-15.
    • (2006) J Biol Chem , vol.281 , pp. 9607-9615
    • Long, X.1    Nephew, K.P.2
  • 13
    • 0037339988 scopus 로고    scopus 로고
    • The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast cancer cells
    • Fan M, Bigsby RM, Nephew KP. The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast cancer cells. Mol Endocrinol 2003; 17:356-65.
    • (2003) Mol Endocrinol , vol.17 , pp. 356-365
    • Fan, M.1    Bigsby, R.M.2    Nephew, K.P.3
  • 14
    • 0029853432 scopus 로고    scopus 로고
    • Estrogen regulation of nuclear matrix-intermediate filament proteins in human breast cancer cells
    • Coutts AS, Davie JR, Dotzlaw H, Murphy LC. Estrogen regulation of nuclear matrix-intermediate filament proteins in human breast cancer cells. J Cellular Biochem 1996; 63:174-84.
    • (1996) J Cellular Biochem , vol.63 , pp. 174-184
    • Coutts, A.S.1    Davie, J.R.2    Dotzlaw, H.3    Murphy, L.C.4
  • 15
    • 34247898925 scopus 로고    scopus 로고
    • Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12
    • Lupien M, Jeyakumar M, Hebert E, Hilmi K, Cotnoir- White D, Loch C, et al. Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12. Mol Endocrinol 2007; 21:797-816.
    • (2007) Mol Endocrinol , vol.21 , pp. 797-816
    • Lupien, M.1    Jeyakumar, M.2    Hebert, E.3    Hilmi, K.4    Cotnoir-White, D.5    Loch, C.6
  • 16
    • 0029978077 scopus 로고    scopus 로고
    • Human estrogen receptor ligand activity inversion mutants: Receptors that interpret antiestrogens as estrogens and estrogens as antiestrogens and discriminate among different antiestrogens
    • Montano MM, Ekena K, Krueger KD, Keller AL, Katzenellenbogen BS. Human estrogen receptor ligand activity inversion mutants: receptors that interpret antiestrogens as estrogens and estrogens as antiestrogens and discriminate among different antiestrogens. Mol Endocrinol 1996; 10:230-42.
    • (1996) Mol Endocrinol , vol.10 , pp. 230-242
    • Montano, M.M.1    Ekena, K.2    Krueger, K.D.3    Keller, A.L.4    Katzenellenbogen, B.S.5
  • 17
    • 0032145883 scopus 로고    scopus 로고
    • Cytokeratin expression in breast cancer: Phenotypic changes associated with disease progression
    • Brotherick I, Robson CN, Browell DA, Shenfine J, White MD, Cunliffe WJ, et al. Cytokeratin expression in breast cancer: phenotypic changes associated with disease progression. Cytometry 1998; 32:301-8.
    • (1998) Cytometry , vol.32 , pp. 301-308
    • Brotherick, I.1    Robson, C.N.2    Browell, D.A.3    Shenfine, J.4    White, M.D.5    Cunliffe, W.J.6
  • 18
    • 1942470138 scopus 로고    scopus 로고
    • Downregulated expression of cytokeratin 18 promotes progression of human breast cancer
    • Woelfle U, Sauter G, Santjer S, Brakenhoff R, Pantel K. Downregulated expression of cytokeratin 18 promotes progression of human breast cancer. Clin Cancer Res 2004; 10:2670-4.
    • (2004) Clin Cancer Res , vol.10 , pp. 2670-2674
    • Woelfle, U.1    Sauter, G.2    Santjer, S.3    Brakenhoff, R.4    Pantel, K.5
  • 19
    • 27544495512 scopus 로고    scopus 로고
    • Progestins initiate a luminal to myoepithelial switch in estrogen-dependent human breast tumors without altering growth
    • Sartorius CA, Harvell DM, Shen T, Horwitz KB. Progestins initiate a luminal to myoepithelial switch in estrogen-dependent human breast tumors without altering growth. Cancer Res 2005; 65:9779-88.
    • (2005) Cancer Res , vol.65 , pp. 9779-9788
    • Sartorius, C.A.1    Harvell, D.M.2    Shen, T.3    Horwitz, K.B.4
  • 20
    • 0032519345 scopus 로고    scopus 로고
    • Differential screening and suppression subtractive hybridization identified genes differentially expressed in an estrogen receptor-positive breast carcinoma cell line
    • Kuang WW, Thompson DA, Hoch RV, Weigel RJ. Differential screening and suppression subtractive hybridization identified genes differentially expressed in an estrogen receptor-positive breast carcinoma cell line. Nucleic Acids Res 1998; 26:1116-23.
    • (1998) Nucleic Acids Res , vol.26 , pp. 1116-1123
    • Kuang, W.W.1    Thompson, D.A.2    Hoch, R.V.3    Weigel, R.J.4
  • 21
    • 0035210802 scopus 로고    scopus 로고
    • Evidence for estrogenic contamination of the MAPK inhibitor PD98059
    • Long X, Gize EA, Nephew K, Bigsby RM. Evidence for estrogenic contamination of the MAPK inhibitor PD98059. Endocrinology 2001; 142:5390-3.
    • (2001) Endocrinology , vol.142 , pp. 5390-5393
    • Long, X.1    Gize, E.A.2    Nephew, K.3    Bigsby, R.M.4
  • 22
    • 8344241132 scopus 로고    scopus 로고
    • Inhibiting proteasomal proteolysis sustains estrogen receptor-alpha activation
    • Fan M, Nakshatri H, Nephew KP. Inhibiting proteasomal proteolysis sustains estrogen receptor-alpha activation. Mol Endocrinol 2004; 18:2603-15.
    • (2004) Mol Endocrinol , vol.18 , pp. 2603-2615
    • Fan, M.1    Nakshatri, H.2    Nephew, K.P.3
  • 24
    • 33846207899 scopus 로고    scopus 로고
    • Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant
    • Fan M, Yan PS, Hartman-Frey C, Chen L, Paik H, Oyer SL, et al. Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant. Cancer Res 2006; 66:11954-66.
    • (2006) Cancer Res , vol.66 , pp. 11954-11966
    • Fan, M.1    Yan, P.S.2    Hartman-Frey, C.3    Chen, L.4    Paik, H.5    Oyer, S.L.6
  • 25
    • 0027369120 scopus 로고    scopus 로고
    • Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines
    • Brown R, Clugston C, Burns P, Edlin A, Vasey P, Vojtesek B, et al. Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines. Int J Cancer 1996; 55:678-84.
    • (1996) Int J Cancer , vol.55 , pp. 678-684
    • Brown, R.1    Clugston, C.2    Burns, P.3    Edlin, A.4    Vasey, P.5    Vojtesek, B.6
  • 26
    • 11144230050 scopus 로고    scopus 로고
    • SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways
    • Jonas BA, Privalsky ML. SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways. J Biol Chem 2004; 279:54676-86.
    • (2004) J Biol Chem , vol.279 , pp. 54676-54686
    • Jonas, B.A.1    Privalsky, M.L.2
  • 28
    • 3042735780 scopus 로고    scopus 로고
    • Distinct effects of the antiestrogen Faslodex on the stability of estrogen receptors-alpha and -beta in the breast cancer cell line MCF-7
    • Peekhaus NT, Chang T, Hayes EC, Wilkinson HA, Mitra SW, Schaeffer JM, Rohrer SP. Distinct effects of the antiestrogen Faslodex on the stability of estrogen receptors-alpha and -beta in the breast cancer cell line MCF-7. J Mol Endocrinol 2004; 32:987-95.
    • (2004) J Mol Endocrinol , vol.32 , pp. 987-995
    • Peekhaus, N.T.1    Chang, T.2    Hayes, E.C.3    Wilkinson, H.A.4    Mitra, S.W.5    Schaeffer, J.M.6    Rohrer, S.P.7
  • 31
    • 0029073127 scopus 로고
    • Specific mutations in the estrogen receptor change the properties of antiestrogens to full agonists
    • Mahfoudi A, Roulet E, Dauvois S, Parker MG, Wahli W. Specific mutations in the estrogen receptor change the properties of antiestrogens to full agonists. Proc Nat Acad Sci USA 1995; 92:4206-10.
    • (1995) Proc Nat Acad Sci USA , vol.92 , pp. 4206-4210
    • Mahfoudi, A.1    Roulet, E.2    Dauvois, S.3    Parker, M.G.4    Wahli, W.5
  • 32
    • 0028786569 scopus 로고
    • Yeast two-hybrid system demonstrates that estrogen receptor dimerization is ligand-dependent in vivo
    • Wang H, Peters GA, Zeng X, Tang M, Ip W, Khan SA. Yeast two-hybrid system demonstrates that estrogen receptor dimerization is ligand-dependent in vivo. The J BiolChem 1995; 270:23322-9.
    • (1995) The J BiolChem , vol.270 , pp. 23322-23329
    • Wang, H.1    Peters, G.A.2    Zeng, X.3    Tang, M.4    Ip, W.5    Khan, S.A.6
  • 33
    • 34250643551 scopus 로고    scopus 로고
    • Cytokeratin-18 is a useful serum biomarker for early determination of response of breast carcinomas to chemotherapy
    • Olofsson MH, Ueno T, Pan Y, Xu R, Cai F, van der Kuip H, et al. Cytokeratin-18 is a useful serum biomarker for early determination of response of breast carcinomas to chemotherapy. Clin Cancer Res 2007; 13:3198-206.
    • (2007) Clin Cancer Res , vol.13 , pp. 3198-3206
    • Olofsson, M.H.1    Ueno, T.2    Pan, Y.3    Xu, R.4    Cai, F.5    Van Der Kuip, H.6
  • 34
    • 0242525131 scopus 로고    scopus 로고
    • Ubiquitin-immunoreactive degradation products of cytokeratin 8/18 correlate with aggressive breast cancer
    • Iwaya K, Ogawa H, Mukai Y, Iwamatsu A, Mukai K. Ubiquitin-immunoreactive degradation products of cytokeratin 8/18 correlate with aggressive breast cancer. Cancer Sci 2003; 94:864-70.
    • (2003) Cancer Sci , vol.94 , pp. 864-870
    • Iwaya, K.1    Ogawa, H.2    Mukai, Y.3    Iwamatsu, A.4    Mukai, K.5
  • 35
    • 12144290503 scopus 로고    scopus 로고
    • Differentiation between cell death modes using measurements of different soluble forms of extracellular cytokeratin 18
    • Kramer G, Erdal H, Mertens HJ, Nap M, Mauermann J, Steiner G, et al. Differentiation between cell death modes using measurements of different soluble forms of extracellular cytokeratin 18. Cancer Res 2004; 64:1751-6.
    • (2004) Cancer Res , vol.64 , pp. 1751-1756
    • Kramer, G.1    Erdal, H.2    Mertens, H.J.3    Nap, M.4    Mauermann, J.5    Steiner, G.6
  • 38
    • 0028983214 scopus 로고
    • Immunohistochemical analysis of cytokeratin #8 as a prognostic factor in invasive breast carcinoma
    • Takei H, Iino Y, Horiguchi J, Kanoh T, Takao Y, Oyama T, et al. Immunohistochemical analysis of cytokeratin #8 as a prognostic factor in invasive breast carcinoma. Anticancer Res 1995; 15:1101-5.
    • (1995) Anticancer Res , vol.15 , pp. 1101-1105
    • Takei, H.1    Iino, Y.2    Horiguchi, J.3    Kanoh, T.4    Takao, Y.5    Oyama, T.6
  • 39
    • 28144440871 scopus 로고    scopus 로고
    • Changes in cytoskeletal protein composition indicative of an epithelialmesenchymal transition in human micrometastatic and primary breast carcinoma cells
    • Willipinski-Stapelfeldt B, Riethdorf S, Assmann V, Woelfle U, Rau T, Sauter G, et al. Changes in cytoskeletal protein composition indicative of an epithelialmesenchymal transition in human micrometastatic and primary breast carcinoma cells. Clin Cancer Res 2005; 11:8006-14.
    • (2005) Clin Cancer Res , vol.11 , pp. 8006-8014
    • Willipinski-Stapelfeldt, B.1    Riethdorf, S.2    Assmann, V.3    Woelfle, U.4    Rau, T.5    Sauter, G.6
  • 40
    • 22944492443 scopus 로고    scopus 로고
    • Transfection of keratin 18 gene in human breast cancer cells causes induction of adhesion proteins and dramatic regression of malignancy in vitro and in vivo
    • Buhler H, Schaller G. Transfection of keratin 18 gene in human breast cancer cells causes induction of adhesion proteins and dramatic regression of malignancy in vitro and in vivo. Mol Cancer Res 2005; 3:365-71.
    • (2005) Mol Cancer Res , vol.3 , pp. 365-371
    • Buhler, H.1    Schaller, G.2
  • 41
    • 33747418929 scopus 로고    scopus 로고
    • DEDD association with cytokeratin filaments correlates with sensitivity to apoptosis
    • Schutte B, Henfling M, Ramaekers FC. DEDD association with cytokeratin filaments correlates with sensitivity to apoptosis. Apoptosis 2006; 11:1561-72.
    • (2006) Apoptosis , vol.11 , pp. 1561-1572
    • Schutte, B.1    Henfling, M.2    Ramaekers, F.C.3
  • 42
    • 33646075716 scopus 로고    scopus 로고
    • Changes in oestrogen receptor-alpha and -beta during progression to acquired resistance to tamoxifen and fulvestrant (Faslodex, ICI 182,780) in MCF7 human breast cancer cells
    • Shaw LE, Sadler AJ, Pugazhendhi D, Darbre PD. Changes in oestrogen receptor-alpha and -beta during progression to acquired resistance to tamoxifen and fulvestrant (Faslodex, ICI 182,780) in MCF7 human breast cancer cells. J Steroid Biochem Mol Biol 2006; 99:19-32.
    • (2006) J Steroid Biochem Mol Biol , vol.99 , pp. 19-32
    • Shaw, L.E.1    Sadler, A.J.2    Pugazhendhi, D.3    Darbre, P.D.4
  • 43
    • 32044470341 scopus 로고    scopus 로고
    • Potential of endogenous estrogen receptor beta to influence the selective ER modulator ERbeta complex
    • Chen B, Gajdos C, Dardes R, Kidwai N, Johnston SR, Dowsett M, et al. Potential of endogenous estrogen receptor beta to influence the selective ER modulator ERbeta complex. Int J Oncol 2005; 27:327-35.
    • (2005) Int J Oncol , vol.27 , pp. 327-335
    • Chen, B.1    Gajdos, C.2    Dardes, R.3    Kidwai, N.4    Johnston, S.R.5    Dowsett, M.6


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