ASICs aggravate acidosis-induced injuries during ischemic reperfusion

Neuroscience Letters

Volumn 479, Issue 1, 2010, Pages 63-68

  Gu, Ling ^a   Liu, Xiaoyu ^a   Yang, Yi ^a   Luo, Dijun ^b   Zheng, Xiaoxiang ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b The University of Texas at Arlington   (United States)

Author keywords

Acid sensing ion channels (ASICs); Acidosis; Hippocampal neuron; OGD; Reperfusion

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1A; AMILORIDE; GLUCOSE; LIPOCORTIN 5; NEUROPROTECTIVE AGENT; PCTX1 VENOM; PROPIDIUM IODIDE; UNCLASSIFIED DRUG; NERVE PROTEIN; SODIUM CHANNEL;

ACIDOSIS; ANIMAL CELL; ANIMAL TISSUE; ANOXIA; APOPTOSIS; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CELL VIABILITY; CONTROLLED STUDY; DESENSITIZATION; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG EFFECT; DRUG MECHANISM; GLUCOSE BRAIN LEVEL; LONG TERM EXPOSURE; NERVE CELL NECROSIS; NEUROPROTECTION; NEWBORN; NONHUMAN; PATCH CLAMP; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; RAT; REPERFUSION INJURY; STAINING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL DEATH; CELL HYPOXIA; DEFICIENCY; DRUG EFFECTS; HIPPOCAMPUS; MEMBRANE POTENTIAL; METABOLISM; NERVE CELL; PATCH CLAMP TECHNIQUE; PATHOPHYSIOLOGY; PH; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME;

ACIDOSIS; ANIMALS; CELL DEATH; CELL HYPOXIA; CELLS, CULTURED; GLUCOSE; HIPPOCAMPUS; HYDROGEN-ION CONCENTRATION; MEMBRANE POTENTIALS; NERVE TISSUE PROTEINS; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SODIUM CHANNELS; TIME FACTORS; ACID SENSING ION CHANNELS;

EID: 77953706080     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.05.029     Document Type: Article

References (27)

1. Almaas R., Pytte M., Lindstad J.K., Wright M., Saugstad O.D., Pleasure D., Rootwelt T. Acidosis has opposite effects on neuronal survival during hypoxia and reoxygenation. J. Neurochem. 2003, 84:1018-1027.
2. Arias R.L., Sung M.L., Vasylyev D., Zhang M.Y., Albinson K., Kubek K., Kagan N., Beyer C., Lin Q., Dwyer J.M., Zaleska M.M., Bowlby M.R., Dunlop J., Monaghan M. Amiloride is neuroprotective in an MPTP model of Parkinson's disease. Neurobiol. Dis. 2008, 31:334-341.
3. Back T., Hoehn M., Mies G., Busch E., Schmitz B., Kohno K., Hossmann K. Penumbral tissue alkalosis in focal cerebral ischemia: relationship to energy metabolism, blood flow, and steady potential. Ann. Neurol. 2000, 47:485-492.
4. Chen C.C., England S., Akopian A.N., Wood J.N. A sensory neuron-specific, proton-gated ion channel. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:10240-10245.
5. Coryell M.W, Ziemann A.E., Westmoreland P.J., Haenfler J.M., Kurjakovic Z., Zha X.M., Price M., Schnizler M.K., Wemmie J.A. Targeting ASIC1a reduces innate fear and alters neuronal activity in the fear circuit. Biol. Psychiatry 2007, 62:1140-1148.
6. Cronberg T., Rytter A., Asztely F., Soder A., Wieloch T. Glucose but not lactate in combination with acidosis aggravates ischemic neuronal death in vitro. Stroke 2004, 35:753-757.
7. de la Rosa D.A., Canessa C.M., Fyfe G.K., Zhang P. Structure and regulation of amiloride-sensitive sodium channels. Annu. Rev. Physiol. 2000, 62:573-594.
8. de la Rosa D.A., Krueger S.R., Kolar A., Shao D., Fitzsimonds R.M., Canessa C.M. Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system. J. Physiol. 2003, 546:77-87.
9. Deval E, Noel J., Lay N., Alloui A., Diochot S., Friend V., Jodar M., Lazdunski M., Lingueglia E. ASIC3, a sensor of acidic and primary inflammatory pain. EMBO J. 2008, 27:3047-3055.
10. Duan B., Wu L.-J., Yu Y.-Q., Ding Y., Jing L., Xu L., Chen J., Xu T.-L. Upregulation of acid-sensing ion channel ASIC1a in spinal dorsal horn neurons contributes to inflammatory pain hypersensitivity. J. Neurosci. 2007, 27:11139-11148.
11. Froyland E., Wibrand F., Almaas R., Dalen I., Lindstad J.K., Rootwelt T. Acidosis during reoxygenation has an early detrimental effect on neuronal metabolic activity. Pediatr. Res. 2005, 57:488-493.
12. Gao J., Duan B., Wang D.G., Deng X.H., Zhang G.Y., Xu L., Xu T.L. Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron 2005, 48:635-646.
13. Giffard R.G., Monyer H., Christine C.W., Choi D.W. Acidosis reduces NMDA receptor activation, glutamate neurotoxicity, and oxygen-glucose deprivation neuronal injury in cortical cultures. Brain Res. 1990, 506:339-342.
14. Gu L, Yang Y., Sun Y., Zheng X. Puerarin inhibits acid-sensing ion channels and protects against neuron death induced by acidosis. Planta Med. 2010, 76:583-588.
15. Kamada Y., Hiramatsu K., Sakaki T. Effects of acidosis on the post-hypoxic recovery of synaptic transmission in gerbil hippocampal slices. Brain Res. 2000, 868:347-351.
16. Li D., Shao Z., Vanden Hoek T.L., Brorson J.R. Reperfusion accelerates acute neuronal death induced by simulated ischemia. Exp. Neurol. 2007, 206:280-287.
17. Nedergaard M., Kraig R.P., Tanabe J., Pulsinelli W.A. Dynamics of interstitial and intracellular pH in evolving brain infarct. Am. J. Physiol. Regul. Integr. Comp. Physiol. 1991, 260:581-588.
18. Pignataro G., Simon R.P., Xiong Z.G. Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischemia. Brain 2007, 130:151-158.
19. Siesjö B., Katsura K., Kristián T. Acidosis-related damage. Adv. Neurol. 1996, 71:209-233. discussion 234-236.
20. Siesjo B.K. Acidosis and ischemic brain damage. Neurochem. Pathol. 1988, 9:31-88.
21. Tomlinson F.H., Anderson R.E., Meyer F.B. Brain pHi, cerebral blood flow, and NADH fluorescence during severe incomplete global ischemia in rabbits. Stroke 1993, 24:435-443.
22. Vukicevic M, Kellenberger S. Modulatory effects of acid-sensing ion channels on action potential generation in hippocampal neurons. Am. J. Physiol.-Cell Physiol. 2004, 287:682-690.
23. Waldmann R., Champigny G., Bassilana F., Heurteaux C., Lazdunski M. A proton-gated cation channel involved in acid-sensing. Nature 1997, 386:173-177.
24. Wemmie J.A., Chen J., Askwith C.C., Hruska-Hageman A.M., Price M.P., Nolan B.C., Yoder P.G., Lamani E., Hoshi T., Freeman J.H., Welsh M.J. The acid-activated ion channel ASIC contributes to synaptic plasticity. Learn. Memory Neuron 2002, 34:463-477.
25. Xiong Z.G., Pignataro G., Li M., Chang S., Simon R.P. Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases. Curr. Opin. Pharmacol. 2008, 8:25-32.
26. Xiong Z.G., Zhu X.M., Chu X.P., Minami M., Hey J., Wei W.L., MacDonald J.F., Wemmie J.A., Price M.P., Welsh M.J., Simon R.P. Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell 2004, 118:687-698.
27. Yermolaieva O., Leonard A.S., Schnizler M.K., Abboud F.M., Welsh M.J. Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:6752-6757.