Glucose but Not Lactate in Combination with Acidosis Aggravates Ischemic Neuronal Death in Vitro

Stroke

Volumn 35, Issue 3, 2004, Pages 753-757

  Cronberg, Tobias ^a   Rytter, Anna ^a   Asztély, Fredrik ^a   Söder, Anna ^a   Wieloch, Tadeusz ^a,b  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Acidosis; Cell culture; Hippocampus; Hyperglycemia; Ischemia

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; GLUCOSE; IONOTROPIC RECEPTOR; LACTIC ACID; PROPIDIUM IODIDE;

ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN SLICE; CELL CULTURE; CONTROLLED STUDY; EXTRACELLULAR FLUID; HIPPOCAMPUS; HYPERGLYCEMIA; IN VITRO STUDY; LACTIC ACIDOSIS; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PH; PRIORITY JOURNAL; RECEPTOR BLOCKING;

ACIDOSIS; ANIMALS; BRAIN ISCHEMIA; CELL DEATH; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; GLUCOSE; HIPPOCAMPUS; HYDROGEN-ION CONCENTRATION; HYPERGLYCEMIA; LACTIC ACID; MICE; MICE, INBRED BALB C; NEURONS; RECEPTORS, GLUTAMATE; TIME FACTORS;

EID: 1442323829     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000117576.09512.32     Document Type: Article

References (30)

1. Myers RE, Yamaguchi S. Nervous system effects of cardiac arrest in monkeys: preservation of vision. Arch Neurol. 1977;34:65-74.
2. Pulsinelli WA, Waldman S, Rawlinson D, Plum F. Moderate hyperglycemia augments ischemic brain damage: a neuropathologic study in the rat. Neurology. 1982;32:1239-1246.
3. Nedergaard M. Transient focal ischemia in hyperglycemic rats is associated with increased cerebral infarction. Brain Res. 1987;408:79-85.
4. Pulsinelli WA, Levy DE, Sigsbee B, Scherer P, Plum F. Increased damage after ischemic stroke in patients with hyperglycemia with or without established diabetes mellitus. Am J Med. 1983;74:540-544.
5. Kagansky N, Levy S, Knobler H. The role of hyperglycemia in acute stroke. Arch Neurol. 2001;58:1209-1212.
6. Woo E, Chan YW, Yu YL, Huang CY. Admission glucose level in relation to mortality and morbidity outcome in 252 stroke patients. Stroke. 1988;19:185-191.
7. Parsons MW, Barber PA, Desmond PM, Baird TA, Darby DG, Byrnes G, Tress BM, Davis SM. Acute hyperglycemia adversely affects stroke outcome: a magnetic resonance imaging and spectroscopy study. Ann Neurol. 2002;52:20-28.
8. Schurr A, West CA, Reid KH, Tseng MT, Reiss SJ, Rigor BM. Increased glucose improves recovery of neuronal function after cerebral hypoxia in vitro. Brain Res. 1987;421:135-139.
9. Goldberg MP, Choi DW. Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury. J Neurosci. 1993;13:3510-3524.
10. Pringle AK, Iannotti F, Wilde GJ, Chad JE, Seeley PJ, Sundstrom LE. Neuroprotection by both NMDA and non-NMDA receptor antagonists in in vitro ischemia. Brain Res. 1997;755:36-46.
11. Rytter A, Cronberg T, Asztély F, Nemali S, Wieloch T. Mouse hippocampal organotypic tissue cultures exposed to in vitro "ischemia" show selective and delayed CA1 damage that is aggravated by glucose. J Cereb Blood Flow Metab. 2003;23:23-33.
12. Andsberg G, Kokaia Z, Lindvall O. Upregulation of p75 neurotrophin receptor after stroke in mice does not contribute to differential vulnerability of striatal neurons. Exp Neurol. 2001;169:351-363.
13. Schmued LC, Albertson C, Slikker W Jr. Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res. 1997;751:37-46.
14. Li PA, Shamloo M, Katsura K, Smith ML, Siesjö, BK. Critical values for plasma glucose in aggravating ischaemic brain damage: correlation to extracellular pH. Neurobiol Dis. 1995;2:97-108.
15. Siesjö BK, Katsura K, Kristian T. Acidosis-related damage. Adv Neurol. 1996;71:209-233; comment 234-206.
16. Katsura K, Kristian T, Smith ML, Siesjö BK. Acidosis induced by hypercapnia exaggerates ischemic brain damage. J Cereb Blood Flow Metab. 1994;14:243-250.
17. Gisselsson L, Smith ML, Siesjö BK. Hyperglycemia and focal brain ischemia. J Cereb Blood Flow Metab. 1999;19:288-297.
18. Xiang Z, Bergold PJ. Synaptic depression and neuronal loss in transiently acidic hippocampal slice cultures. Brain Res. 2000;881:77-87.
19. Bouzier-Sore AK, Merle M, Magistretti PJ, Pellerin L. Feeding active neurons: (re)emergence of a nursing role for astrocytes. J Physiol Paris. 2002;96:273-282.
20. Deitmer JW. Strategies for metabolic exchange between glial cells and neurons. Respir Physiol. 2001;129:71-81.
21. Smith ML, von Hanwehr R, Siesjö BK. Changes in extra- and intracellular pH in the brain during and following ischemia in hyperglycemic and in moderately hypoglycemic rats. J Cereb Blood Flow Metab. 1986;6:574-583.
22. Siemkowicz E, Hansen AJ. Brain extracellular ion composition and EEG activity following 10 minutes ischemia in normo- and hyperglycemic rats. Stroke. 1981;12:236-240.
23. Giffard RG, Monyer H, Christine CW, Choi DW. Acidosis reduces NMDA receptor activation, glutamate neurotoxicity, and oxygen-glucose deprivation neuronal injury in cortical cultures. Brain Res. 1990;506:339-342.
24. Newell DW, Barth A, Papermaster V, Malouf AT. Glutamate and nonglutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures. J Neurosci. 1995;15:7702-7711.
25. Plum F. What causes infarction in ischemic brain? The Robert Wartenberg lecture. Neurology. 1983;33:222-233.
26. Hulse RE, Winterfield J, Kunkler PE, Kraig RP. Astrocytic clasmatodendrosis in hippocampal organ culture. Glia. 2001;33:169-179.
27. Zimmerman GA, Meistrell M III, Bloom O, Cockroft KM, Bianchi M, Risucci D, Broome J, Farmer P, Cerami A, Vlassara H, et al. Neurotoxicity of advanced glycation endproducts during focal stroke and neuroprotective effects of aminoguanidine. Proc Natl Acad Sci USA. 1995;92:3744-3748.
28. Kikuchi S, Shinpo K, Takeuchi M, Yamagishi S, Makita Z, Sasaki N, Tashiro K. Glycation: a sweet tempter for neuronal death. Brain Res Brain Res Rev. 2003;41:306-323.
29. Arai K, Maguchi S, Fujii S, Ishibashi H, Oikawa K, Taniguchi N. Glycation and inactivation of human Cu-Zn-superoxide dismutase: identification of the in vitro glycated sites. J Biol Chem. 1987;262:16969-16972.
30. Russell JW, Golovoy D, Vincent AM, Mahendru P, Olzmann JA, Mentzer A, Feldman EL. High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB J. 2002;16:1738-1748.