Pantothenate kinase-2 (Pank2) silencing causes cell growth reduction, cell-specific ferroportin upregulation and iron deregulation

Neurobiology of Disease

Volumn 39, Issue 2, 2010, Pages 204-210

  Poli, Maura ^a   Derosas, Manuela ^a   Luscieti, Sara ^a   Cavadini, Patrizia ^a   Campanella, Alessandro ^b,c   Verardi, Rosanna ^d   Finazzi, Dario ^a,e   Arosio, Paolo ^a,e  

^a UNIVERSITY OF BRESCIA   (Italy)

^b Research Unit of Molecular Neuroscience   (Italy)

^c VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^d Section of Immunohematology and Transfusional Medicine   (Italy)

^e Spedali Civili di Brescia   (Italy)

Author keywords

Ferritin; Ferroportin; Iron metabolism; Neurodegeneration with brain iron accumulation; Pantothenate kinase

Indexed keywords

ACONITATE HYDRATASE; COENZYME A; FERROPORTIN; IRON; MESSENGER RNA; MITOCHONDRIAL ENZYME; PANTOTHENATE KINASE 2; SMALL INTERFERING RNA;

ARTICLE; BIOACCUMULATION; CATALYSIS; CELL GROWTH; CELL LINE; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE INDUCTION; GENE SILENCING; GLIOMA CELL; GLOBUS PALLIDUS; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; IRON BALANCE; IRON DEFICIENCY; IRON STORAGE; IRON TRANSPORT; MOTOR DYSFUNCTION; NEUROBLASTOMA CELL; NEURODEGENERATION WITH BRAIN IRON ACCUMULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ACONITATE HYDRATASE; CATION TRANSPORT PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMANS; IRON; MITOCHONDRIA; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTOPORPHYRINS; RNA, MESSENGER; RNA, SMALL INTERFERING; SUPEROXIDE DISMUTASE;

EID: 77953703758     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2010.04.009     Document Type: Article

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