-
1
-
-
0036263128
-
Development of a derivatization method, coupled with reverse phase HPLC, for monitoring the formation of an enolate intermediate
-
Abrahim A, Hartman R, Ge Z, Mao B, Marcoux J, (2002). Development of a derivatization method, coupled with reverse phase HPLC, for monitoring the formation of an enolate intermediate J. Liq. Chromatogr. Rel. Technol. 25: 1049-1062.
-
(2002)
J. Liq. Chromatogr. Rel. Technol.
, vol.25
, pp. 1049-1062
-
-
Abrahim, A.1
Hartman, R.2
Ge, Z.3
Mao, B.4
Marcoux, J.5
-
2
-
-
0034836419
-
Dose proportionality of oral etoricoxib, a highly selective cyclooxygenase-2 inhibitor, in healthy volunteers
-
Agrawal NG, Porras AG, Matthews CZ, Woolf EJ, Miller JL, Mukhopadhyay S, Neu DC, Gottesdiener KM, (2001). Dose proportionality of oral etoricoxib, a highly selective cyclooxygenase-2 inhibitor, in healthy volunteers. J. Clin. Pharmacol. 41: 1106-1110
-
(2001)
J. Clin. Pharmacol.
, vol.41
, pp. 1106-1110
-
-
Agrawal, N.G.1
Porras, A.G.2
Matthews, C.Z.3
Woolf, E.J.4
Miller, J.L.5
Mukhopadhyay, S.6
Neu, D.C.7
Gottesdiener, K.M.8
-
3
-
-
77953666001
-
-
Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B, Day R, Ferraz MB, Hawkey CJ, Hochberg MC, Kvien TK, Schnitzer TJ, (2000). Comparison of upper gastrointestinal toxicityof rofecoxib and naproxen in patients with rheumatoid arthritis.
-
(2000)
Comparison of Upper Gastrointestinal Toxicityof Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis
-
-
Bombardier, C.1
Laine, L.2
Reicin, A.3
Shapiro, D.4
Burgos-Vargas, R.5
Davis, B.6
Day, R.7
Ferraz, M.B.8
Hawkey, C.J.9
Hochberg, M.C.10
Kvien, T.K.11
Schnitzer, T.J.12
-
4
-
-
77953672246
-
-
VIGOR study group following 1528
-
VIGOR study group N. Engl. J. Med. 343: 1520-1528, 1522 p following 1528.
-
N. Engl. J. Med.
, vol.343
, Issue.1520-1528
, pp. 1522
-
-
-
6
-
-
0032788729
-
Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3-phenyl-2- (5H)-furanone]: A potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles
-
Chan CC, Boyce S, Brideau C, Charleson W, Cromlish W, Ethier D, Evans J, Ford-Hutchinson AW, Forrest MJ, Gauthier JY, Gordon R, Gresser M, Guay J, Kargman S, Kennedy B, Leblanc Y, Leger S, Mancini J, O'Neill GP, Ouellet M, Patrick D, Percival MD, Perrier H, Mahasen et al. 345 Prasit P, Rodger I (1999). Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3-phenyl-2-(5H)- furanone]: A potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles. Pharmacol. Exp. Ther. 290: 551-560
-
(1999)
Pharmacol. Exp. Ther.
, vol.290
, pp. 551-560
-
-
Chan, C.C.1
Boyce, S.2
Brideau, C.3
Charleson, W.4
Cromlish, W.5
Ethier, D.6
Evans, J.7
Ford-Hutchinson, A.W.8
Forrest, M.J.9
Gauthier, J.Y.10
Gordon, R.11
Gresser, M.12
Guay, J.13
Kargman, S.14
Kennedy, B.15
Leblanc, Y.16
Leger, S.17
Mancini, J.18
O'Neill, G.P.19
Ouellet, M.20
Patrick, D.21
Percival, M.D.22
Perrier, H.23
Prasit, P.24
Rodger, I.25
more..
-
7
-
-
0035938410
-
In Vitro Metabolism Considerations, Including Activity Testing of Metabolites, in the Discovery and Selection of the COX-2 Inhibitor Etoricoxib (MK- 0663)
-
Chauret N, Yergey JA, Brideau C, Friesen RW, Mancini J, Riendeau D, Silva J, Styhler A, Trimble LA, Nicoll-Griffith DA, (2001). In Vitro Metabolism Considerations, Including Activity Testing of Metabolites, in the Discovery and Selection of the COX-2 Inhibitor Etoricoxib (MK- 0663) Bioorg. Med. Chem. Lett.11(2001): 1059-1062.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, Issue.2001
, pp. 1059-1062
-
-
Chauret, N.1
Yergey, J.A.2
Brideau, C.3
Friesen, R.W.4
Mancini, J.5
Riendeau, D.6
Silva, J.7
Styhler, A.8
Trimble, L.A.9
Nicoll-Griffith, D.A.10
-
9
-
-
0037568022
-
Characterization of etoricoxib, a novel, selective COX-2 inhibitor
-
Dallob A, Hawkey CJ, Greenberg H, Wight N, De Schepper P, Waldman S, Wong P, DeTora L, Gertz B, Agrawal N, Wagner J, Gottesdiener K, (2003). Characterization of etoricoxib, a novel, selective COX-2 inhibitor. J. Clin. Pharmacol. 43 :573-585
-
(2003)
J. Clin. Pharmacol.
, vol.43
, pp. 573-585
-
-
Dallob, A.1
Hawkey, C.J.2
Greenberg, H.3
Wight, N.4
De Schepper, P.5
Waldman, S.6
Wong, P.7
Detora, L.8
Gertz, B.9
Agrawal, N.10
Wagner, J.11
Gottesdiener, K.12
-
11
-
-
0032491270
-
2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: Selective and orally active cyclooxygenase-2 inhibitors
-
Friesen RW, Brideau C, Chan CC, Charleson S, Deschenes D, Dube D, Etheir D, Fortin R, Gauthier JY, Girard Y, Gorden R, Greig GM, Riendeau D, Savoie C, Wang Z, Wong Z, Visco D, Xu LJ, Young RN, (1998). 2-Pyridinyl-3-(4- methylsulfonyl)phenylpyridines: selective and orally active cyclooxygenase-2 inhibitors. Bioorg. Med. Chem. Lett. 19: 2777-2782
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 2777-2782
-
-
Friesen, R.W.1
Brideau, C.2
Chan, C.C.3
Charleson, S.4
Deschenes, D.5
Dube, D.6
Etheir, D.7
Fortin, R.8
Gauthier, J.Y.9
Girard, Y.10
Gorden, R.11
Greig, G.M.12
Riendeau, D.13
Savoie, C.14
Wang, Z.15
Wong, Z.16
Visco, D.17
Xu, L.J.18
Young, R.N.19
-
13
-
-
0041832232
-
Development and Validation of an HPLC Method for the Impurity and Quantitative Analysis of Etoricoxib
-
Hartmann R, Abrahim A, Clausen A, Mao B, Crocker LS, Ge Z (2003). Development and Validation of an HPLC Method for the Impurity and Quantitative Analysis of Etoricoxib. J. Liq. Chromatogr. Rel. Technol. 26: 2551-2566.
-
(2003)
J. Liq. Chromatogr. Rel. Technol.
, vol.26
, pp. 2551-2566
-
-
Hartmann, R.1
Abrahim, A.2
Clausen, A.3
Mao, B.4
Crocker, L.S.5
Ge, Z.6
-
14
-
-
0033031331
-
COX-2 inhibitors
-
Hawley C, (1999). COX-2 inhibitors. Lancet 353: 307.
-
(1999)
Lancet
, vol.353
, pp. 307
-
-
Hawley, C.1
-
15
-
-
0035946023
-
High-throughput, semi-automated determination of a cyclooxygenase II inhibitor in human plasma and urine using solid-phase extraction in the 96-well format and high-performance liquid chromatography with post-column photochemical derivatization-fluorescence detection
-
DOI 10.1016/S0378-4347(00)00475-8, PII S0378434700004758
-
Matthews CZ, Woolf EJ, Lin L, Fang W, Hsieh J, Ha S, Simpson R, Matuszewski BK, (2001). High-throughput, semi-automated determination of a cyclooxygenase II inhibitor in human plasma and urine using solid-phase extraction in the 96-well format and high-performance liquid chromatography with post-column photochemical derivatization-fluorescence detection. J. Chromatogr. B 751: 237-246 (Pubitemid 32126311)
-
(2001)
Journal of Chromatography B: Biomedical Sciences and Applications
, vol.751
, Issue.2
, pp. 237-246
-
-
Matthews, C.Z.1
Woolf, E.J.2
Lin, L.3
Fang, W.4
Hsieh, J.5
Ha, S.6
Simpson, R.7
Matuszewski, B.K.8
-
17
-
-
31344436945
-
Simultaneous quantitation of etoricoxib, salicylic acid, valdecoxib, ketoprofen, nimesulide and celecoxib in plasma by highperformance liquid chromatography with UV detection
-
Pavan Kumar VV, Vinu MC, Ramani AV, Mullangi R, Srinivas NR (2006). Simultaneous quantitation of etoricoxib, salicylic acid, valdecoxib, ketoprofen, nimesulide and celecoxib in plasma by highperformance liquid chromatography with UV detection. Biomed. Chromatogr. 20: 125-132
-
(2006)
Biomed. Chromatogr.
, vol.20
, pp. 125-132
-
-
Pavan Kumar, V.V.1
Vinu, M.C.2
Ramani, A.V.3
Mullangi, R.4
Srinivas, N.R.5
-
18
-
-
13444266910
-
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methylphenyl)- 3(trifluoromethyl)-1h-pyrazol-1-yl]benzenesulfonamide (sc-58635, celecoxib)
-
DOI 10.1021/jm960803q
-
Penning TD, Talley JJ, Bertenshaw SR, Carter JS, Collins PW, Docter S, Graneto MJ, Lee LF, Malecha JW, Miyashiro JM, Rodgers RS, Rogier DJ, Yu SS, Anderson GD, Burton EG, Cogburn JN, Gregory SA, Koboldt CM, Perkins WE, Seibert K, Veenhuizen AW, Zhanng YY, Isakson PC, (1997). Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] benze nesulfonamide (SC-58635, celecoxib). J. Med. Chem. 40: 1347-1365 (Pubitemid 27198082)
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, Issue.9
, pp. 1347-1365
-
-
Penning, T.D.1
Talley, J.J.2
Bertenshaw, S.R.3
Carter, J.S.4
Collins, P.W.5
Docter, S.6
Graneto, M.J.7
Lee, L.F.8
Malecha, J.W.9
Miyashiro, J.M.10
Rogers, R.S.11
Rogier, D.J.12
Yu, S.S.13
Anderson, G.D.14
Burton, E.G.15
Cogburn, J.N.16
Gregory, S.A.17
Koboldt, C.M.18
Perkins, W.E.19
Seibert, K.20
Veenhuizen, A.W.21
Zhang, Y.Y.22
Isakson, P.C.23
more..
-
19
-
-
0033526928
-
The discovery of rofecoxib, [MK 966, Vioxx, 4-(4′- methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor
-
Prasit P, Wang Z, Brideau C, Chan C C, Charleson S, Cromlish W, Ethier D, Evans JF, Ford-Hutchinson AW, Gauthier JY, Gordon R, Guay J, Gresser M, Kargman S, Kennedy B, Leblanc Y, Leger S, Mancini J, O'Neill GP, Ouellet M, Percival MD, Perrier H, Riendeau D, Rodger I, Zamboni R, (1999). The discovery of rofecoxib, [MK 966, Vioxx, 4-(4′-methylsulfonylphenyl)-3-phenyl-2(5H)- furanone], an orally active cyclooxygenase-2-inhibitor. Bioorg. Med. Chem. Lett. 9: 1773-1778
-
(1999)
Bioorg. Med. Chem. Lett.
, vol.9
, pp. 1773-1778
-
-
Prasit, P.1
Wang, Z.2
Brideau, C.3
Chan, C.C.4
Charleson, S.5
Cromlish, W.6
Ethier, D.7
Evans, J.F.8
Ford-Hutchinson, A.W.9
Gauthier, J.Y.10
Gordon, R.11
Guay, J.12
Gresser, M.13
Kargman, S.14
Kennedy, B.15
Leblanc, Y.16
Leger, S.17
Mancini, J.18
O'Neill, G.P.19
Ouellet, M.20
Percival, M.D.21
Perrier, H.22
Riendeau, D.23
Rodger, I.24
Zamboni, R.25
more..
-
20
-
-
12444264940
-
Validated liquid chromatographic ultraviolet method for the quantitation of Etoricoxib in human plasma using liquid-liquid extraction
-
Ramakrishna NVS, Vishwottam KN, Wishu S, Koteshwara M, (2005). Validated liquid chromatographic ultraviolet method for the quantitation of Etoricoxib in human plasma using liquid-liquid extraction. J. Chromatogr. B, 816: 215-221.
-
(2005)
J. Chromatogr. B
, vol.816
, pp. 215-221
-
-
Ramakrishna, N.V.S.1
Vishwottam, K.N.2
Wishu, S.3
Koteshwara, M.4
-
21
-
-
0028904461
-
Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent
-
Rao CV, Rivenson A, Simi B, Zang E, Kelloff G, Steele V, Reddy BS (1995). Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent. Cancer Res. 55: 1464-1472.
-
(1995)
Cancer Res.
, vol.55
, pp. 1464-1472
-
-
Rao, C.V.1
Rivenson, A.2
Simi, B.3
Zang, E.4
Kelloff, G.5
Steele, V.6
Reddy, B.S.7
-
22
-
-
0029794742
-
Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis
-
Reddy BS, Rao CV, Seibert K, (1996). Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis. Cancer Res. 56: 4566-4569. (Pubitemid 26338047)
-
(1996)
Cancer Research
, vol.56
, Issue.20
, pp. 4566-4569
-
-
Reddy, B.S.1
Rao, C.V.2
Seibert, K.3
-
23
-
-
0035145462
-
Etoricoxib (MK-0663): Preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2
-
Riendeau D, Percival MD, Brideau C, Charleson S, Dube D, Etheir D, Falgueyret JP, Friesen RW, Girard Y, Gorden R, Greig GM, Guay J, Mancini J, Ouellet M, Wong E, Visco D, Xu LJ, Boyce S, Girard Y, Prasit P, Zamboni R, Gresser M, Ford AW, Young HRN, Chan CC, (2001). Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2. J. Pharm. Exp. Ther. 296: 558-566
-
(2001)
J. Pharm. Exp. Ther.
, vol.296
, pp. 558-566
-
-
Riendeau, D.1
Percival, M.D.2
Brideau, C.3
Charleson, S.4
Dube, D.5
Etheir, D.6
Falgueyret, J.P.7
Friesen, R.W.8
Girard, Y.9
Gorden, R.10
Greig, G.M.11
Guay, J.12
Mancini, J.13
Ouellet, M.14
Wong, E.15
Visco, D.16
Xu, L.J.17
Boyce, S.18
Girard, Y.19
Prasit, P.20
Zamboni, R.21
Gresser, M.22
Ford, A.W.23
Young, H.R.N.24
Chan, C.C.25
more..
-
24
-
-
0036173226
-
Simultaneous determination of unlabeled and carbon-13-labeled etoricoxib, a new cyclooxygenase-2 inhibitor, in human plasma using HPLC-MS/MS
-
Rose MJ, Agrawal N, Woolf EJ, Matuszewski BK, (2002). Simultaneous determination of unlabeled and carbon-13-labeled etoricoxib, a new cyclooxygenase-2 inhibitor, in human plasma using HPLC-MS/MS. J. Pharm. Sci. 91: 405-412.
-
(2002)
J. Pharm. Sci.
, vol.91
, pp. 405-412
-
-
Rose, M.J.1
Agrawal, N.2
Woolf, E.J.3
Matuszewski, B.K.4
-
25
-
-
4344661128
-
Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: Randomised controlled trial
-
DOI 10.1016/S0140-6736(04)16893-1, PII S0140673604168931
-
Schnitzer TJ, Burmester GR, Mysler E, Hochberg MC, Doherty M, Ehrsam E, Gitton X, Krammer G, Mellein B, Matchaba P, Gimona A, Hawkey CJ; TARGET Study Group. (2004). Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial. Lancet 364: 665-674 (Pubitemid 39140622)
-
(2004)
Lancet
, vol.364
, Issue.9435
, pp. 665-674
-
-
Schnitzer, T.J.1
Burmester, G.R.2
Mysler, E.3
Hochberg, M.C.4
Doherty, M.5
Ehrsam, E.6
Gitton, X.7
Krammer, G.8
Mellein, B.9
Matchaba, P.10
Gimona, A.11
Hawkey, C.J.12
-
26
-
-
4143107932
-
Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition
-
Simmons DL, Botting RM, Hla T, (2004). Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition Pharmacol. Rev. 56: 387-437.
-
(2004)
Pharmacol. Rev.
, vol.56
, pp. 387-437
-
-
Simmons, D.L.1
Botting, R.M.2
Hla, T.3
-
27
-
-
32844455611
-
Celecoxib versus naproxen and diclofenac in osteoarthritis patients: SUCCESSI Study
-
SUCCESS-I Investigators
-
Singh G, Fort JG, Goldstein JL, Levy RA, Hanrahan PS, Bello AE, Andrade-Ortega L, Wallemark C, Agrawal NM, Eisen GM, Stenson WF, Triadafilopoulos G; SUCCESS-I Investigators. (2006). Celecoxib versus naproxen and diclofenac in osteoarthritis patients: SUCCESSI Study. Am J. Med. 119: 255-266
-
(2006)
Am J. Med.
, vol.119
, pp. 255-266
-
-
Singh, G.1
Fort, J.G.2
Goldstein, J.L.3
Levy, R.A.4
Hanrahan, P.S.5
Bello, A.E.6
Andrade-Ortega, L.7
Wallemark, C.8
Agrawal, N.M.9
Eisen, G.M.10
Stenson, W.F.11
Triadafilopoulos, G.12
-
28
-
-
0037249213
-
The second generation of COX-2 inhibitors: What advantages do the newest offer?
-
Stichtenoth DO, Frolich JC, (2003). The second generation of COX-2 inhibitors: what advantages do the newest offer? Drugs. 63:33-45.
-
(2003)
Drugs
, vol.63
, pp. 33-45
-
-
Stichtenoth, D.O.1
Frolich, J.C.2
-
29
-
-
15844385651
-
A liquid chromatography-mass spectrometry method for the quantification of both etoricoxib and valdecoxib in human plasma
-
DOI 10.1002/bmc.423
-
Werner U, Werner D, Hinz B, Lambrecht C, Brune K (2005). A liquid chromatography-mass spectrometry method for the quantification of both etoricoxib and valdecoxib in human plasma. Biomed Chromatogr. 19: 113-118. (Pubitemid 40425694)
-
(2005)
Biomedical Chromatography
, vol.19
, Issue.2
, pp. 113-118
-
-
Werner, U.1
Werner, D.2
Hinz, B.3
Lambrecht, C.4
Brune, K.5
|