A liquid chromatography-mass spectrometry method for the quantification of both etoricoxib and valdecoxib in human plasma

Biomedical Chromatography

Volumn 19, Issue 2, 2005, Pages 113-118

  Werner, Ulrike ^a   Werner, Dierk ^b   Hinz, Burkhard ^a   Lambrecht, Christoph ^a   Brune, Kay ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b HELIOS KLINIKEN SCHWERIN   (Germany)

Author keywords

Cyclooxygenase 2 inhibitors; HPLC APCI MS; Pharmacokinetic profiles

Indexed keywords

ATMOSPHERIC IONIZATION; ATMOSPHERIC PRESSURE; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; PLASMA (HUMAN); POSITIVE IONS;

ATMOSPHERIC PRESSURE CHEMICAL IONIZATION; CYCLO-OXYGENASE-2 INHIBITOR; ETORICOXIB; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY/ATMOSPHERIC PRESSURE CHEMICAL IONIZATION MS; HUMAN PLASMAS; ION TRAPS; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; PHARMACOKINETIC PROFILES; VALDECOXIB;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ETORICOXIB; VALDECOXIB;

AREA UNDER THE CURVE; ARTICLE; ATMOSPHERIC PRESSURE; BLOOD SAMPLING; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG RETENTION; DRUG STRUCTURE; HUMAN; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NORMAL HUMAN; PHASE TRANSITION; PLASMA; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS; VOLUNTEER;

EID: 15844385651     PISSN: 02693879     EISSN: None     Source Type: Journal    
DOI: 10.1002/bmc.423     Document Type: Article

References (12)

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