메뉴 건너뛰기




Volumn 16, Issue 7, 2010, Pages 1371-1385

Single amino acid changes in the predicted RNase H domain of Escherichia coli RNase G lead to complementation of RNase e deletion mutants

Author keywords

Cell viability; Chimeric proteins; mRNA decay; rRNA maturation; tRNA processing

Indexed keywords

BACTERIAL PROTEIN; CYSTEINE; HISTIDINE; MESSENGER RNA; PROLINE; PROTEIN RNG 219; PROTEIN RNG 248; RIBONUCLEASE; RIBONUCLEASE E; RIBONUCLEASE G; TRANSFER RNA; UNCLASSIFIED DRUG; ESCHERICHIA COLI PROTEIN; RNG PROTEIN, E COLI;

EID: 77953636824     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.2104810     Document Type: Article
Times cited : (28)

References (50)
  • 2
    • 0017887243 scopus 로고
    • A conditional lethal mutant of Escherichia coli which affects the processing of ribosomal RNA
    • Apirion D, Lasser AB. 1978. A conditional lethal mutant of Escherichia coli which affects the processing of ribosomal RNA. J Biol Chem 253: 1738-1742. (Pubitemid 8312357)
    • (1978) Journal of Biological Chemistry , vol.253 , Issue.5 , pp. 1738-1742
    • Apirion, D.1    Lassar, A.B.2
  • 3
    • 0024095739 scopus 로고
    • Stabilization of discrete mRNA breakdown products in ams pnp rnb multiple mutants of Escherichia coli K-12
    • Arraiano CM, Yancey SD, Kushner SR. 1988. Stabilization of discrete mRNA breakdown products in ams pnp rnb multiple mutants of Escherichia coli K-12. J Bacteriol 170: 4625-4633.
    • (1988) J Bacteriol , vol.170 , pp. 4625-4633
    • Arraiano, C.M.1    Yancey, S.D.2    Kushner, S.R.3
  • 5
    • 0027391014 scopus 로고
    • Analysis of mRNA decay and rRNA processing in Escherichia coli multiple mutants carrying a deletion in RNase III
    • Babitzke P, Granger L, Olszewski J, Kushner SR. 1993. Analysis of mRNA decay and rRNA processing in Escherichia coli multiple mutants carrying a deletion in RNase III. J Bacteriol 175: 229-239. (Pubitemid 23016671)
    • (1993) Journal of Bacteriology , vol.175 , Issue.1 , pp. 229-239
    • Babitzke, P.1    Granger, L.2    Olszewski, J.3    Kushner, S.R.4
  • 6
    • 4143073655 scopus 로고    scopus 로고
    • Exchange of regions between bacterial poly(A) polymerase and the CCA-adding enzyme generates altered specificities
    • Betat H, Rammelt C, Martin G, Morl M. 2004. Exchange of regions between bacterial poly(A) polymerase and the CCA-adding enzyme generates altered specificities. Mol Cell 15: 389-398.
    • (2004) Mol Cell , vol.15 , pp. 389-398
    • Betat, H.1    Rammelt, C.2    Martin, G.3    Morl, M.4
  • 7
  • 8
    • 33644752796 scopus 로고    scopus 로고
    • Identification and analysis of Escherichia coli ribonuclease E dominant-negative mutants
    • Briegel KJ, Baker A, Jain C. 2006. Identification and analysis of Escherichia coli ribonuclease E dominant-negative mutants. Genetics 172: 7-15.
    • (2006) Genetics , vol.172 , pp. 7-15
    • Briegel, K.J.1    Baker, A.2    Jain, C.3
  • 9
    • 0030891309 scopus 로고    scopus 로고
    • Northern blotting of RNA denatured in glyoxal without buffer recirculation
    • Burnett WV. 1997. Northern blotting of RNA denatured in glyoxal without buffer recirculation. Biotechniques 22: 668-671.
    • (1997) Biotechniques , vol.22 , pp. 668-671
    • Burnett, W.V.1
  • 10
    • 27144495430 scopus 로고    scopus 로고
    • Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover
    • Callaghan AJ, Marcaida MJ, Stead JA, McDowall KJ, Scott WG, Luisi BF. 2005. Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover. Nature 437: 1187-1191.
    • (2005) Nature , vol.437 , pp. 1187-1191
    • Callaghan, A.J.1    Marcaida, M.J.2    Stead, J.A.3    McDowall, K.J.4    Scott, W.G.5    Luisi, B.F.6
  • 11
    • 34250875706 scopus 로고    scopus 로고
    • Initiation of RNA decay in Escherichia coli by 5′ pyrophosphate removal
    • Celesnik H, Deana A, Belasco JG. 2007. Initiation of RNA decay in Escherichia coli by 5′ pyrophosphate removal. Mol Cell 27: 79-90.
    • (2007) Mol Cell , vol.27 , pp. 79-90
    • Celesnik, H.1    Deana, A.2    Belasco, J.G.3
  • 13
    • 0036172167 scopus 로고    scopus 로고
    • Geno3D: Automatic comparative molecular modelling of protein
    • Combet C, Jambon M, Deleage G, Geourjan C. 2002. Geno3D: Automatic comparative molecular modelling of protein. Bioinformatics 18: 213-214. (Pubitemid 34145058)
    • (2002) Bioinformatics , vol.18 , Issue.1 , pp. 213-214
    • Combet, C.1    Jambon, M.2    Deleage, G.3    Geourjon, C.4
  • 14
    • 1442325396 scopus 로고    scopus 로고
    • The function of RNase G in Escherichia coli is constrained by its amino and carboxyl termini
    • Deana A, Belasco JG. 2004. The function of RNase G in Escherichia coli is constrained by its amino and carboxyl termini. Mol Microbiol 51: 1205-1217.
    • (2004) Mol Microbiol , vol.51 , pp. 1205-1217
    • Deana, A.1    Belasco, J.G.2
  • 15
    • 0029924182 scopus 로고    scopus 로고
    • Synonymous codon selection controls in vivo turnover and amount of mRNA in Escherichia coli bla and ompA genes
    • Deana A, Ehrlich R, Reiss C. 1996. Synonymous codon selection controls in vivo turnover and amount of mRNA in Escherichia coli bla and ompA genes. J Bacteriol 178: 2718-2720.
    • (1996) J Bacteriol , vol.178 , pp. 2718-2720
    • Deana, A.1    Ehrlich, R.2    Reiss, C.3
  • 16
    • 0030033310 scopus 로고    scopus 로고
    • Differential mRNA stability of the cspA gene in the cold-shock response of Escherichia coli
    • Goldenberg D, Azar I, Oppenheim AB. 1996. Differential mRNA stability of the cspA gene in the cold-shock response of Escherichia coli. Mol Microbiol 19: 241-248. (Pubitemid 26037262)
    • (1996) Molecular Microbiology , vol.19 , Issue.2 , pp. 241-248
    • Goldenberg, D.1    Azar, I.2    Oppenheim, A.B.3
  • 17
    • 0344389019 scopus 로고    scopus 로고
    • E. coli rpsO mRNA decay: RNase E processing at the beginning of the coding sequence stimulates poly(A)-dependent degradation of the mRNA
    • Hajnsdorf E, Regnier P. 1999. E. coli rpsO mRNA decay: RNase E processing at the beginning of the coding sequence stimulates poly(A)-dependent degradation of the mRNA. J Mol Biol 286: 1033-1043.
    • (1999) J Mol Biol , vol.286 , pp. 1033-1043
    • Hajnsdorf, E.1    Regnier, P.2
  • 18
    • 0028235826 scopus 로고
    • Roles of RNase E, RNase II and PNPase in the degradation of the rpsO transcripts of Escherichia coli: Stabilizing function of RNase II and evidence for efficient degradation in an ams pnp rnb mutant
    • Hajnsdorf E, Steier O, Coscoy L, Teysset L, Régnier P. 1994. Roles of RNase E, RNase II and PNPase in the degradation of the rpsO transcripts of Escherichia coli: Stabilizing function of RNase II and evidence for efficient degradation in an ams pnp rnb mutant. EMBO J 13: 3368-3377.
    • (1994) EMBO J , vol.13 , pp. 3368-3377
    • Hajnsdorf, E.1    Steier, O.2    Coscoy, L.3    Teysset, L.4    Régnier, P.5
  • 19
    • 0029825005 scopus 로고    scopus 로고
    • Multiple degradation pathways of the rpsO mRNA of Escherichia coli. RNase E interacts with the 5′ and 3′ extremities of the primary transcript
    • Hajnsdorf E, Braun F, Haugel-Nielsen J, Le Derout J, Régnier P. 1996. Multiple degradation pathways of the rpsO mRNA of Escherichia coli. RNase E interacts with the 5′ and 3′ extremities of the primary transcript. Biochimie 78: 416-424.
    • (1996) Biochimie , vol.78 , pp. 416-424
    • Hajnsdorf, E.1    Braun, F.2    Haugel-Nielsen, J.3    Le Derout, J.4    Régnier, P.5
  • 20
    • 34250323480 scopus 로고    scopus 로고
    • Role of RNA structure and susceptibility to RNase E in regulation of a cold shock mRNA, cspA mRNA
    • Hankins JS, Zappavigna C, Prud'homme-Genereux A, Mackie GA. 2007. Role of RNA structure and susceptibility to RNase E in regulation of a cold shock mRNA, cspA mRNA. J Bacteriol 189: 4353-4358.
    • (2007) J Bacteriol , vol.189 , pp. 4353-4358
    • Hankins, J.S.1    Zappavigna, C.2    Prud'homme-Genereux, A.3    Mackie, G.A.4
  • 21
  • 22
    • 0042497078 scopus 로고    scopus 로고
    • RNase G-dependent degradation of the eno mRNA encoding a glycolysis enzyme enolase in Escherichia coli
    • Kaga N, Umitsuki G, Nagai K, Wachi M. 2002. RNase G-dependent degradation of the eno mRNA encoding a glycolysis enzyme enolase in Escherichia coli. Biosci Biotechnol Biochem 66: 2216-2220.
    • (2002) Biosci Biotechnol Biochem , vol.66 , pp. 2216-2220
    • Kaga, N.1    Umitsuki, G.2    Nagai, K.3    Wachi, M.4
  • 23
    • 0017697982 scopus 로고
    • Gene affecting longevity of messenger RNA: A mutant of Escherichia coli with altered mRNA stability
    • Kuwano M, Ono M, Endo H, Hori K, Nakamura K, Hirota Y, Ohnishi Y. 1977. Gene affecting longevity of messenger RNA: A mutant of Escherichia coli with altered mRNA stability. Mol Gen Genet 154: 279-285.
    • (1977) Mol Gen Genet , vol.154 , pp. 279-285
    • Kuwano, M.1    Ono, M.2    Endo, H.3    Hori, K.4    Nakamura, K.5    Hirota, Y.6    Ohnishi, Y.7
  • 24
    • 0036274640 scopus 로고    scopus 로고
    • RNase G complementation of rne null mutation identified functional interrelationships with RNase E in Escherichia coli
    • Lee K, Bernstein JA, Cohen SN. 2002. RNase G complementation of rne null mutation identified functional interrelationships with RNase E in Escherichia coli. Mol Microbiol 43: 1445-1456.
    • (2002) Mol Microbiol , vol.43 , pp. 1445-1456
    • Lee, K.1    Bernstein, J.A.2    Cohen, S.N.3
  • 25
    • 0036210631 scopus 로고    scopus 로고
    • RNase E plays an essential role in the maturation of Escherichia coli tRNA precursors
    • Li Z, Deutscher MP. 2002. RNase E plays an essential role in the maturation of Escherichia coli tRNA precursors. RNA 8: 97-109.
    • (2002) RNA , vol.8 , pp. 97-109
    • Li, Z.1    Deutscher, M.P.2
  • 26
    • 0033577789 scopus 로고    scopus 로고
    • RNase G (CafA protein) and RNase E are both required for the 5′ maturation of 16S ribosomal RNA
    • Li Z, Pandit S, Deutscher MP. 1999. RNase G (CafA protein) and RNase E are both required for the 5′ maturation of 16S ribosomal RNA. EMBO J 18: 2878-2885.
    • (1999) EMBO J , vol.18 , pp. 2878-2885
    • Li, Z.1    Pandit, S.2    Deutscher, M.P.3
  • 27
    • 0033607239 scopus 로고    scopus 로고
    • RNase E is required for the maturation of ssrA and normal ssrA RNA peptide-tagging activity
    • Lin-Chao S, Wei C-L, Lin Y-T. 1999. RNase E is required for the maturation of ssrA and normal ssrA RNA peptide-tagging activity. Proc Natl Acad Sci 96: 12406-12411.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 12406-12411
    • Lin-Chao, S.1    Wei, C.-L.2    Lin, Y.-T.3
  • 28
    • 0033048415 scopus 로고    scopus 로고
    • The C-terminal half of RNase E, which organizes the Escherichia coli degradosome, participates in mRNA degradation but not rRNA processing in vivo
    • Lopez PJ, Marchand I, Joyce SA, Dreyfus M. 1999. The C-terminal half of RNase E, which organizes the Escherichia coli degradosome, participates in mRNA degradation but not rRNA processing in vivo. Mol Microbiol 33: 188-199.
    • (1999) Mol Microbiol , vol.33 , pp. 188-199
    • Lopez, P.J.1    Marchand, I.2    Joyce, S.A.3    Dreyfus, M.4
  • 29
    • 0029295957 scopus 로고
    • Processing of the precursor to the catalytic RNA subunit of RNase P from Escherichia coli
    • Lundberg U, Altman S. 1995. Processing of the precursor to the catalytic RNA subunit of RNase P from Escherichia coli. RNA 1: 327-334.
    • (1995) RNA , vol.1 , pp. 327-334
    • Lundberg, U.1    Altman, S.2
  • 30
    • 0025796969 scopus 로고
    • Specific endonucleolytic cleavage of the mRNA for ribosomal protein S20 of Escherichia coli requires the products of the ams gene in vivo and in vitro
    • Mackie GA. 1991. Specific endonucleolytic cleavage of the mRNA for ribosomal protein S20 of Escherichia coli requires the products of the ams gene in vivo and in vitro. J Bacteriol 173: 2488-2497.
    • (1991) J Bacteriol , vol.173 , pp. 2488-2497
    • Mackie, G.A.1
  • 31
    • 0032531768 scopus 로고    scopus 로고
    • Ribonuclease E is a 5′-end-dependent endonuclease
    • Mackie GA. 1998. Ribonuclease E is a 5′-end-dependent endonuclease. Nature 395: 720-723.
    • (1998) Nature , vol.395 , pp. 720-723
    • Mackie, G.A.1
  • 32
    • 0141860088 scopus 로고    scopus 로고
    • Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli
    • Masse R, Escorcia FE, Gottesman S. 2003. Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli. Genes Dev 17: 2374-2383.
    • (2003) Genes Dev , vol.17 , pp. 2374-2383
    • Masse, R.1    Escorcia, F.E.2    Gottesman, S.3
  • 33
    • 39149140707 scopus 로고    scopus 로고
    • Rho-independent transcription terminators inhibit RNase P processing of the secG leuU and metT tRNA polycistronic transcripts in Escherichia coli
    • Mohanty BK, Kushner SR. 2008. Rho-independent transcription terminators inhibit RNase P processing of the secG leuU and metT tRNA polycistronic transcripts in Escherichia coli. Nucleic Acids Res 36: 364-375.
    • (2008) Nucleic Acids Res , vol.36 , pp. 364-375
    • Mohanty, B.K.1    Kushner, S.R.2
  • 35
    • 0027955358 scopus 로고
    • Cytoplasmic axial filaments in Escherichia coli cells: Possible function in the mechanism of chromosome segregation and cell division
    • Okada Y, Wachi M, Hirata A, Suzuki K, Nagai K, Matsuhashi M. 1994. Cytoplasmic axial filaments in Escherichia coli cells: Possible function in the mechanism of chromosome segregation and cell division. J Bacteriol 176: 917-922. (Pubitemid 24043982)
    • (1994) Journal of Bacteriology , vol.176 , Issue.3 , pp. 917-922
    • Okada, Y.1    Wachi, M.2    Hirata, A.3    Suzuki, K.4    Nagai, K.5    Matsuhashi, M.6
  • 36
    • 13744261009 scopus 로고    scopus 로고
    • A novel endoribonuclease, RNase LS, in Escherichia coli
    • Otsuka Y, Yonesaki T. 2005. A novel endoribonuclease, RNase LS, in Escherichia coli. Genetics 169: 13-20.
    • (2005) Genetics , vol.169 , pp. 13-20
    • Otsuka, Y.1    Yonesaki, T.2
  • 37
    • 0036571060 scopus 로고    scopus 로고
    • Initiation of tRNA maturation by RNase E is essential for cell viability in E. coli
    • Ow MC, Kushner SR. 2002. Initiation of tRNA maturation by RNase E is essential for cell viability in E. coli. Genes Dev 16: 1102-1115.
    • (2002) Genes Dev , vol.16 , pp. 1102-1115
    • Ow, M.C.1    Kushner, S.R.2
  • 38
    • 0033636189 scopus 로고    scopus 로고
    • Analysis of mRNA decay and rRNA processing in Escherichia coli in the absence of RNase E-based degradosome assembly
    • Ow MC, Liu Q, Kushner SR. 2000. Analysis of mRNA decay and rRNA processing in Escherichia coli in the absence of RNase E-based degradosome assembly. Mol Microbiol 38: 854-866.
    • (2000) Mol Microbiol , vol.38 , pp. 854-866
    • Ow, M.C.1    Liu, Q.2    Kushner, S.R.3
  • 39
    • 0036197752 scopus 로고    scopus 로고
    • RNase E levels in Escherichia coli are controlled by a complex regulatory system that involves transcription of the rne gene from three promoters
    • Ow MC, Liu Q, Mohanty BK, Andrew ME, Maples VF, Kushner SR. 2002. RNase E levels in Escherichia coli are controlled by a complex regulatory system that involves transcription of the rne gene from three promoters. Mol Microbiol 43: 159-171.
    • (2002) Mol Microbiol , vol.43 , pp. 159-171
    • Ow, M.C.1    Liu, Q.2    Mohanty, B.K.3    Andrew, M.E.4    Maples, V.F.5    Kushner, S.R.6
  • 40
    • 0042665928 scopus 로고    scopus 로고
    • RNase G of Escherichia coli exhibits only limited functional overlap with its essential homologue, RNase E
    • Ow MC, Perwez T, Kushner SR. 2003. RNase G of Escherichia coli exhibits only limited functional overlap with its essential homologue, RNase E. Mol Microbiol 49: 607-622.
    • (2003) Mol Microbiol , vol.49 , pp. 607-622
    • Ow, M.C.1    Perwez, T.2    Kushner, S.R.3
  • 41
    • 33645826534 scopus 로고    scopus 로고
    • RNase Z in Escherichia coli plays a significant role in mRNA decay
    • Perwez T, Kushner SR. 2006. RNase Z in Escherichia coli plays a significant role in mRNA decay. Mol Microbiol 60: 723-737.
    • (2006) Mol Microbiol , vol.60 , pp. 723-737
    • Perwez, T.1    Kushner, S.R.2
  • 42
    • 52649171479 scopus 로고    scopus 로고
    • Intragenic suppressors of temperature-sensitive rne mutations lead to the dissociation of RNase E activity on mRNA and tRNA substrates in Escherichia coli
    • Perwez T, Hami D, Maples VF, Min Z, Wang BC, Kushner SR. 2008. Intragenic suppressors of temperature-sensitive rne mutations lead to the dissociation of RNase E activity on mRNA and tRNA substrates in Escherichia coli. Nucleic Acids Res 36: 5306-5318.
    • (2008) Nucleic Acids Res , vol.36 , pp. 5306-5318
    • Perwez, T.1    Hami, D.2    Maples, V.F.3    Min, Z.4    Wang, B.C.5    Kushner, S.R.6
  • 43
    • 0019515477 scopus 로고
    • Transfer RNA precursors are accumulated in Escherichia coli in the absence of RNase E
    • Ray BK, Apirion D. 1981. Transfer RNA precursors are accumulated in Escherichia coli in the absence of RNase E. Eur J Biochem 114: 517-524.
    • (1981) Eur J Biochem , vol.114 , pp. 517-524
    • Ray, B.K.1    Apirion, D.2
  • 44
    • 33745885282 scopus 로고    scopus 로고
    • RNase E maintenance of proper FtsZ/FtsA ratio required for nonfilamentous growth of Escherichia coli cells but not for colony-forming ability
    • Tamura M, Lee K, Miller CA, Moore CJ, Shirako Y, Kobayashi M, Cohen SN. 2006. RNase E maintenance of proper FtsZ/FtsA ratio required for nonfilamentous growth of Escherichia coli cells but not for colony-forming ability. J Bacteriol 188: 5145-5152.
    • (2006) J Bacteriol , vol.188 , pp. 5145-5152
    • Tamura, M.1    Lee, K.2    Miller, C.A.3    Moore, C.J.4    Shirako, Y.5    Kobayashi, M.6    Cohen, S.N.7
  • 45
    • 0034708447 scopus 로고    scopus 로고
    • The CafA protein required for the 5′-maturation of 16 S rRNA is a 5′-end-dependent ribonuclease that has context-dependent broad sequence specificity
    • Tock MR, Walsh AP, Carroll G, McDowall KJ. 2000. The CafA protein required for the 5′-maturation of 16 S rRNA is a 5′-end-dependent ribonuclease that has context-dependent broad sequence specificity. J Biol Chem 275: 8726-8732.
    • (2000) J Biol Chem , vol.275 , pp. 8726-8732
    • Tock, M.R.1    Walsh, A.P.2    Carroll, G.3    McDowall, K.J.4
  • 46
    • 0035018365 scopus 로고    scopus 로고
    • Involvement of RNase G in in vivo mRNA metabolism in Escherichia coli
    • Umitsuki G, Wachi M, Takada A, Hikichi T, Nagia K. 2001. Involvement of RNase G in in vivo mRNA metabolism in Escherichia coli. Genes Cells 6: 403-410.
    • (2001) Genes Cells , vol.6 , pp. 403-410
    • Umitsuki, G.1    Wachi, M.2    Takada, A.3    Hikichi, T.4    Nagia, K.5
  • 47
    • 0031020242 scopus 로고    scopus 로고
    • Functional relationship between Escherichia coli RNase e and the CafA protein
    • Wachi M, Umitsuki G, Nagai K. 1997. Functional relationship between Escherichia coli RNase E and the CafA protein. Mol Gen Genet 253: 515-519. (Pubitemid 127512186)
    • (1997) Molecular Genetics and Genomics , vol.253 , Issue.4 , pp. 515-519
    • Wachi, M.1    Umitsuki, G.2    Nagai, K.3
  • 48
    • 0033532514 scopus 로고    scopus 로고
    • Escherichia coli cafA gene encodes a novel RNase, designated as RNase G, involved in processing of the 5′ end of 16S rRNA
    • Wachi M, Umitsuki G, Shimizu M, Takada A, Nagai K. 1999. Escherichia coli cafA gene encodes a novel RNase, designated as RNase G, involved in processing of the 5′ end of 16S rRNA. Biochem Biophys Res Commun 259: 483-488.
    • (1999) Biochem Biophys Res Commun , vol.259 , pp. 483-488
    • Wachi, M.1    Umitsuki, G.2    Shimizu, M.3    Takada, A.4    Nagai, K.5
  • 49
    • 0035931008 scopus 로고    scopus 로고
    • A novel RNase G mutant that is defective in degradation of adhE mRNA but proficient in the processing of 16S rRNA precursor
    • Wachi M, Naoko K, Umitsuki G, Clarke DP, Nagai K. 2001. A novel RNase G mutant that is defective in degradation of adhE mRNA but proficient in the processing of 16S rRNA precursor. Biochem Biophys Res Commun 289: 1301-1306.
    • (2001) Biochem Biophys Res Commun , vol.289 , pp. 1301-1306
    • Wachi, M.1    Naoko, K.2    Umitsuki, G.3    Clarke, D.P.4    Nagai, K.5
  • 50
    • 0025782890 scopus 로고
    • Construction of versatile low-copynumber vectors for cloning, sequencing and expression in Escherichia coli
    • Wang RF, Kushner SR. 1991. Construction of versatile low-copynumber vectors for cloning, sequencing and expression in Escherichia coli. Gene 100: 195-199.
    • (1991) Gene , vol.100 , pp. 195-199
    • Wang, R.F.1    Kushner, S.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.