Identification and characterization of important residues in the catalytic mechanism of CMP-Neu5Ac synthetase from Neisseria meningitidis

FEBS Journal

Volumn 277, Issue 13, 2010, Pages 2779-2790

  Horsfall, Louise E ^a   Nelson, Adam ^a   Berry, Alan ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

CMP Neu5Ac; Enzyme kinetics; N acylneuraminate cytidylyltransferase; Sialic acid

Indexed keywords

ACYLNEURAMINATE CYTIDYLYLTRANSFERASE; PYROPHOSPHATE; SIALIC ACID;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME KINETICS; METAL BINDING; MUTATION; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STEADY STATE;

BIOCATALYSIS; CATALYTIC DOMAIN; CYTIDINE MONOPHOSPHATE N-ACETYLNEURAMINIC ACID; KINETICS; N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE; NEISSERIA MENINGITIDIS; POINT MUTATION;

MAMMALIA; NEISSERIA MENINGITIDIS;

EID: 77953590143     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2010.07696.x     Document Type: Article

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