Structure of a Sialic Acid-activating Synthetase, CMP-acylneuraminate Synthetase in the Presence and Absence of CDP

Journal of Biological Chemistry

Volumn 276, Issue 11, 2001, Pages 8190-8196

  Mosimann, Steven C ^a,c   Gilbert, Michel ^b   Dombroswki, Dennise ^a   To, Rebecca ^b   Wakarchuk, Warren ^b   Strynadka, Natalie C J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c UNIVERSITY OF LETHBRIDGE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIODIVERSITY; CELLS; ENZYMES; SUBSTRATES; SYNTHESIS (CHEMICAL); VIRUSES; X RAY CRYSTALLOGRAPHY;

DRUG DESIGN;

ORGANIC ACIDS;

ACYLNEURAMINATE CYTIDYLYLTRANSFERASE; CYTIDINE DIPHOSPHATE; N ACETYLNEURAMINIC ACID;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL VIRULENCE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME ISOLATION; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; CHEMISTRY; DIMERIZATION; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE;

BACTERIA (MICROORGANISMS); HAEMOPHILUS; MAMMALIA; NEISSERIA; NEISSERIA MENINGITIDIS; STREPTOCOCCUS SP. 'GROUP B';

AMINO ACID SEQUENCE; BINDING SITES; CYTIDINE DIPHOSPHATE; DIMERIZATION; MOLECULAR SEQUENCE DATA; N-ACETYLNEURAMINIC ACID; N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY;

EID: 0035896636     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M007235200     Document Type: Article

References (41)

1. Munster, A. K., Eckhardt, M., Potvin, B., Muhlenhoff, M., Stanley, P., and Gerardy-Schahn, R. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 9140-9145
2. Haft, R. F., Wessels, M. R., Mebane, M. F., Conaty, N., and Rubens, C. E. (1996) Mol Microbiol. 19, 555-563
3. Kelm, S., and Schauer, R. (1997) Int. Rev. Cytol. 175, 137-240
4. Kern, W. F., Spier, C. M., Miller, T. P., and Grogan, T. M. (1993) Leuk. Lymphoma 12, 1-10
5. Rosenberg, A. (1995) The Biology of Sialic Acids, Plenum Press, New York
6. Jann, B., and Jann, K. (1990) Curr. Top. Micorbiol. Immunol. 150, 19-42
7. Rest, R. F., and Frangipane, J. V. (1992) Infect. Immun. 60, 989-997
8. Lagergard, T. (1992) Microb. Pathog. 13, 203-217
9. Bitter-Suermann, D. (1993) Polysialic Acid: From Microbe to Man, Birkhauser Verlag, Basel
10. Jann, K., and Jann, B. (1985) The Virulence of Escherichia coli: Reviews and Methods, Academic Press, Orlando, Florida
11. Timmis, K. N., Boulnois, G. J., Bitter, S. D., and Cabello, F. C. (1985) Curr. Top. Microbiol. Immunol. 118, 197-218
12. Mandrell, R. E., and Apicella, M. A. (1993) Immunobiology 187, 382-402
13. Kean, E. L. (1991) Glycobiology 5, 441-447
14. Warren, L., and Blacklow, R. S. (1962) J. Biol. Chem. 237, 3527-3534
15. Roseman, S. (1962) Proc. Natl. Acad. Sci. U. S. A. 48, 437-441
16. Kapitonov, D., and Yu, R. K. (1999) Glycobiology 9, 961-978
17. Gilbert, M., Bayer, R., Cunningham, A. M., DeFrees, S., Gao, Y., Watson, D. C., Young, N. M., and Wakarchuk, W. W. (1998) Nat. Biotechnol. 16, 769-772
18. Gilbert, M., Watson, D. C., and Wakarchuk, W. (1997) Biotech. Lett. 19, 417-420
19. Ramakrishnan, V., Finch, J. T., Graziano, V., Lee, P. L., and Sweet, R. M. (1993) Nature 362, 219-223
20. Miller, R., Gallo, S. M., Khalak, H. G., and Weeks, C. M. (1994) J. Appl. Cryst. 27, 613-621
21. Terwilliger, T. C., and Berendzen, J. (1999) Acta Crystallogr. Sect. D Biol. Crystallogr. 55, 849-861
22. Collaborative Computational Project, Number 4. (1994) Acta Crystallogr. Sect. D Biol. Crystallogr. 50, 760-763
23. McRee, D. E. (1993) Practical Protein Crystallography, Academic Press, San Diego, CA
24. Navaza, J. (1994) Acta Crystallogr. Sect. A 50, 157-163
25. Brunger, A. T., Adams, P. D., Clore, G. M., Delano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J.-S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 905-921
26. Chan, A. W. E., Hutchinson, E. G., Harris, D., and Thornton, J. M. (1993) Protein Sci. 2, 1574-1590
27. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Cryst. 26, 283-291
28. Nicholls, A., Sharp, K., and Honig, B. (1991) Proteins Struct. Funct. Genet. 11, 281-296
29. Hart, T. N., Ness, S. R., and Read, R. J. (1997) Proteins Struct. Funct. Genet. Suppl. 1, 205-209
30. Kraulis, P. K. (1991) J. Appl. Cryst. 24, 946-950
31. Orengo, C. A., Michie, A. D., Jones, S., Jones, D. T., Swindells, M. B., and Thornton, J. M. (1997) Structure 5, 1093-1108
32. Richardson, J. S., and Richardson, D. C. (1989) Principles and Patterns of Protein Conformation, Plenum Press, New York
33. Tullius, M. V., Vann, W. F., and Gibson, B. W. (1999) Protein Sci. 8, 666-675
34. Petsko, G. A., Kenyon, G. L., Gerlt, J. A., Ringe, D., and Kozarich, J. W. (1993) Trends Biochem. Sci. 18, 372-376
35. Schwabe, C. (1996) FASEB. J. 10, 184-185
36. Holm, L., and Sander, C. (1993) J. Mol. Biol. 233, 123-138
37. Schulz, G. E. (1992) Faraday Discuss. 93, 85-93
38. Jelakovic, S., Jann, K., and Schulz, G. E. (1996) FEBS Lett. 391, 157-161
39. Samuels, N. M., Gibson, B. W., and Miller, S. M. (1999) Biochemistry 38, 6195-6203
40. Stoughton, D. M., Zapata, G., Picone, R., and Vann, W. F. (1999) Biochem. J. 343, 397-402
41. Ambrose, M. E., Freese, S. J., Reinhold, M. S., Warner, T. G., and Vann, W. F. (1992) Biochemistry 31, 775-780