Advances in Campylobacter biology and implications for biotechnological applications

Microbial Biotechnology

Volumn 3, Issue 3, 2010, Pages 242-258

  Jeon, Byeonghwa ^a   Muraoka, Wayne T ^a,b   Zhang, Qijing ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b NATIONAL ANIMAL DISEASE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL VACCINE; BACTERIOCIN; CIPROFLOXACIN; E 760; ERYTHROMYCIN; MACROLIDE; OR 7; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RECOMBINANT FLAC VACCINE; RECOMBINANT FSPA1 VACCINE; RECOMBINANT FSPA2 VACCINE; RECOMBINANT VACCINE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

BACTERIOPHAGE; BIOLOGICAL TRAIT; BIOTECHNOLOGY; CAMPYLOBACTER JEJUNI; ENVIRONMENTAL STRESS; ESCHERICHIA COLI; HUMAN; IMMUNIZATION; NONHUMAN; PATHOGENESIS; PROTEIN GLYCOSYLATION; REVIEW; SALMONELLA;

ANIMALS; BIOTECHNOLOGY; CAMPYLOBACTER INFECTIONS; CAMPYLOBACTER JEJUNI; HUMANS;

ANIMALIA; BACTERIA (MICROORGANISMS); CAMPYLOBACTER; CAMPYLOBACTER JEJUNI; ESCHERICHIA COLI; EUKARYOTA; SALMONELLA;

EID: 77953579655     PISSN: 17517907     EISSN: 17517915     Source Type: Journal    
DOI: 10.1111/j.1751-7915.2009.00118.x     Document Type: Review

References (167)

1. Alaimo, C., Catrein, I., Morf, L., Marolda, C.L., Callewaert, N., Valvano, M.A., et al. (2006) Two distinct but interchangeable mechanisms for flipping of lipid-linked oligosaccharides. EMBO J 25: 967-976. (Pubitemid 43372111)
2. Allos, B.M. (2001) Campylobacter jejuni infections: update on emerging issues and trends. Clin Infect Dis 32: 1201-1206.
3. Andersen-Nissen, E., Smith, K.D., Strobe, K.L., Barrett, S.L., Cookson, B.T., Logan, S.M., and Aderem, A. (2005) Evasion of Toll-like receptor 5 by flagellated bacteria. Proc Natl Acad Sci USA 102: 9247-9252. (Pubitemid 40923549)
4. Asakura, H., Yamasaki, M., Yamamoto, S., and Igimi, S. (2007) Deletion of peb4 gene impairs cell adhesion and biofilm formation in Campylobacter jejuni. FEMS Microbiol Lett 275: 278-285. (Pubitemid 47437862)
5. Atack, J.M., and Kelly, D.J. (2007) Structure, mechanism and physiological roles of bacterial cytochrome c peroxidases. Adv Microb Physiol 52: 73-106.
6. Atterbury, R.J., Connerton, P.L., Dodd, C.E., Rees, C.E., and Connerton, I.F. (2003) Application of host-specific bacteriophages to the surface of chicken skin leads to a reduction in recovery of Campylobacter jejuni. Appl Environ Microbiol 69: 6302-6306. (Pubitemid 37280360)
7. Avrain, L., Vernozy-Rozand, C., and Kempf, I. (2004) Evidence for natural horizontal transfer of tetO gene between Campylobacter jejuni strains in chickens. J Appl Microbiol 97: 134-140. (Pubitemid 38869890)
8. Bacon, D.J., Alm, R.A., Burr, D.H., Hu, L., Kopecko, D.J., Ewing, C.P., et al. (2000) Involvement of a plasmid in virulence of Campylobacter jejuni 81-176. Infect Immun 68: 4384-4390. (Pubitemid 30497702)
9. Bacon, D.J., Szymanski, C.M., Burr, D.H., Silver, R.P., Alm, R.A., and Guerry, P. (2001) A phase-variable capsule is involved in virulence of Campylobacter jejuni 81-176. Mol Microbiol 40: 769-777.
10. Baqar, S., Applebee, L.A., Gilliland, T.C., Jr, Lee, L.H., Porter, C.K., and Guerry, P. (2008) Immunogenicity and protective efficacy of recombinant Campylobacter jejuni flagellum-secreted proteins in mice. Infect Immun 76: 3170-3175.
11. Barnes, I.H., Bagnall, M.C., Browning, D.D., Thompson, S.A., Manning, G., and Newell, D.G. (2007) Gamma-glutamyl transpeptidase has a role in the persistent colonization of the avian gut by Campylobacter jejuni. Microb Pathog 43: 198-207. (Pubitemid 47405152)
12. Bingham-Ramos, L.K., and Hendrixson, D.R. (2008) Characterization of two putative cytochrome c peroxidases of Campylobacter jejuni involved in promoting commensal colonization of poultry. Infect Immun 76: 1105-1114.
13. Black, R.E., Levine, M.M., Clements, M.L., Hughes, T.P., and Blaser, M.J. (1988) Experimental Campylobacter jejuni infection in humans. J Infect Dis 157: 472-479.
14. Blaser, M.J., and Engberg, J. (2008) Clinical aspects of Campylobacter jejuni and Campylobacter coli infections. In Campylobacter. Nachamkin, I., Szymanski, C., and Blaser, M.J. (eds).Washington, DC, USA: ASM Press, pp. 99-121.
15. de Boer, P., Wagenaar, J.A., Achterberg, R.P., van Putten, J.P., Schouls, L.M., and Duim, B. (2002) Generation of Campylobacter jejuni genetic diversity in vivo. Mol Microbiol 44: 351-359. (Pubitemid 34429741)
16. Bras, A.M., Chatterjee, S., Wren, B.W., Newell, D.G., and Ketley, J.M. (1999) A novel Campylobacter jejuni two-component regulatory system important for temperature-dependent growth and colonization. J Bacteriol 181: 3298-3302. (Pubitemid 29236942)
17. Caldwell, M.B., Guerry, P., Lee, E.C., Burans, J.P., and Walker, R.I. (1985) Reversible expression of flagella in Campylobacter jejuni. Infect Immun 50: 941-943. (Pubitemid 16216898)
18. Clark, C.G., and Ng, L.K. (2008) Sequence variability of Campylobacter temperate bacteriophages. BMC Microbiol 8: 49.
19. Cordwell, S.J., Len, A.C., Touma, R.G., Scott, N.E., Falconer, L., Jones, D., et al. (2008) Identification of membrane-associated proteins from Campylobacter jejuni strains using complementary proteomics technologies. Proteomics 8: 122-139.
20. Cotter, P.D., Hill, C., and Ross, R.P. (2005) Bacteriocins: developing innate immunity for food. Nat Rev Microbiol 3: 777-788.
21. Cremades, N., Bueno, M., Toja, M., and Sancho, J. (2005) Towards a new therapeutic target: Helicobacter pylori flavodoxin. Biophys Chem 115: 267-276. (Pubitemid 40327070)
22. Du, L.F., Li, Z.J., Tang, X.Y., Huang, J.Q., and Sun, W.B. (2008) Immunogenicity and immunoprotection of recombinant PEB1 in Campylobacter jejuni-infected mice. World J Gastroenterol 14: 6244-6248.
23. Engberg, J., Aarestrup, F.M., Taylor, D.E., Gerner-Smidt, P., and Nachamkin, I. (2001) Quinolone and macrolide resistance in Campylobacter jejuni and C. coli: resistance mechanisms and trends in human isolates. Emerg Infect Dis 7: 24-34. (Pubitemid 32173330)
24. Feldman, M.F., Wacker, M., Hernandez, M., Hitchen, P.G., Marolda, C.L., Kowarik, M., et al. (2005) Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli. Proc Natl Acad Sci USA 102: 3016-3021. (Pubitemid 40299908)
25. Fouts, D.E., Mongodin, E.F., Mandrell, R.E., Miller, W.G., Rasko, D.A., Ravel, J., et al. (2005) Major structural differences and novel potential virulence mechanisms from the genomes of multiple Campylobacter species. PLoS Biol 3: e15. (Pubitemid 40318109)
26. Friedman, C.R., Neimann, J., Wegener, H.C., and Tauxe, R.V. (2000) Epidemiology of Campylobacter jejuni infections in the United States and other industrialized nations. In Campylobacter. Nachamkin, I., and Blaser, M.J. (eds). Washington, DC, USA: ASM Press, pp. 121-138.
27. Gaynor, E.C., Wells, D.H., MacKichan, J.K., and Falkow, S. (2005) The Campylobacter jejuni stringent response controls specific stress survival and virulence-associated phenotypes. Mol Microbiol 56: 8-27.
28. Gibreel, A., Kos, V.N., Keelan, M., Trieber, C.A., Levesque, S., Michaud, S., and Taylor, D.E. (2005) Macrolide resistance in Campylobacter jejuni and Campylobacter coli: molecular mechanism and stability of the resistance phenotype. Antimicrob Agents Chemother 49: 2753-2759. (Pubitemid 40917588)
29. Gibreel, A., Wetsch, N.M., and Taylor, D.E. (2007) Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. Antimicrob Agents Chemother 51: 3212-3216. (Pubitemid 350067530)
30. Gillespie, I.A., O'Brien, S.J., Penman, C., Tompkins, D., Cowden, J., and Humphrey, T.J. (2008) Demographic determinants for Campylobacter infection in England and Wales: implications for future epidemiological studies. Epidemiol Infect 136: 1717-1725.
31. Glover, K.J., Weerapana, E., and Imperiali, B. (2005) In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation. Proc Natl Acad Sci USA 102: 14255-14259. (Pubitemid 41429685)
32. Golden, N.J., and Acheson, D.W. (2002) Identification of motility and autoagglutination Campylobacter jejuni mutants by random transposon mutagenesis. Infect Immun 70: 1761-1771.
33. Gu, R., Su, C.C., Shi, F., Li, M., McDermott, G., Zhang, Q., and Yu, E.W. (2007) Crystal structure of the transcriptional regulator CmeR from Campylobacter jejuni. J Mol Biol 372: 583-593. (Pubitemid 47313482)
34. Guccione, E., Leon-Kempis, M.R., Pearson, B.M., Hitchin, E., Mulholland, F., van Diemen, P.M., et al. (2008) Amino acid-dependent growth of Campylobacter jejuni: key roles for aspartase (AspA) under microaerobic and oxygen-limited conditions and identification of AspB (Cj0762), essential for growth on glutamate. Mol Microbiol 69: 77-93. (Pubitemid 351832756)
35. Guerry, P., and Szymanski, C.M. (2008) Campylobacter sugars sticking out. Trends Microbiol 16: 428-435.
36. Guerry, P., Alm, R.A., Power, M.E., Logan, S.M., and Trust, T.J. (1991) Role of two flagellin genes in Campylobacter motility. J Bacteriol 173: 4757-4764.
37. Guerry, P., Pope, P.M., Burr, D.H., Leifer, J., Joseph, S.W., and Bourgeois, A.L. (1994) Development and characterization of recA mutants of Campylobacter jejuni for inclusion in attenuated vaccines. Infect Immun 62: 426-432. (Pubitemid 24033759)
38. Guerry, P., Ewing, C.P., Schirm, M., Lorenzo, M., Kelly, J., Pattarini, D., et al. (2006) Changes in flagellin glycosylation affect Campylobacter autoagglutination and virulence. Mol Microbiol 60: 299-311.
39. Guo, B., Wang, Y., Shi, F., Barton, Y.W., Plummer, P., Reynolds, D.L., et al. (2008) CmeR functions as a pleiotropic regulator and is required for optimal colonization of Campylobacter jejuni in vivo. J Bacteriol 190: 1879-1890. (Pubitemid 351355311)
40. Han, J., Sahin, O., Barton, Y.W., and Zhang, Q. (2008) Key role of Mfd in the development of fluoroquinolone resistance in Campylobacter jejuni. PLoS Pathog 4: e1000083.
41. Hannula, M., and Hanninen, M.L. (2008) Effect of putative efflux pump inhibitors and inducers on the antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli. J Med Microbiol 57: 851-855.
42. Hazeleger, W.C., Wouters, J.A., Rombouts, F.M., and Abee, T. (1998) Physiological activity of Campylobacter jejuni far below the minimal growth temperature. Appl Environ Microbiol 64: 3917-3922.
43. Hendrixson, D.R. (2006) A phase-variable mechanism controlling the Campylobacter jejuni FlgR response regulator influences commensalism. Mol Microbiol 61: 1646-1659.
44. Hendrixson, D.R. (2008) Restoration of flagellar biosynthesis by varied mutational events in Campylobacter jejuni. Mol Microbiol 70: 519-536.
45. Hendrixson, D.R., and Dirita, V.J. (2003) Transcription of sigma54-dependent but not sigma28-dependent flagellar genes in Campylobacter jejuni is associated with formation of the flagellar secretory apparatus. Mol Microbiol 50: 687-702.
46. Hendrixson, D.R., and Dirita, V.J. (2004) Identification of Campylobacter jejuni genes involved in commensal colonization of the chick gastrointestinal tract. Mol Microbiol 52: 471-484.
47. Hiratsuka, T., Furihata, K., Ishikawa, J., Yamashita, H., Itoh, N., Seto, H., and Dairi, T. (2008) An alternative menaquinone biosynthetic pathway operating in microorganisms. Science 321: 1670-1673.
48. Hoffman, P.S., and Goodman, T.G. (1982) Respiratory physiology and energy conservation efficiency of Campylobacter jejuni. J Bacteriol 150: 319-326.
49. Hofreuter, D., Tsai, J., Watson, R.O., Novik, V., Altman, B., Benitez, M., et al. (2006) Unique features of a highly pathogenic Campylobacter jejuni strain. Infect Immun 74: 4694-4707. (Pubitemid 44157257)
50. Hofreuter, D., Novik, V., and Galan, J.E. (2008) Metabolic diversity in Campylobacter jejuni enhances specific tissue colonization. Cell Host Microbe 4: 425-433.
51. Hughes, N.J., Clayton, C.L., Chalk, P.A., and Kelly, D.J. (1998) Helicobacter pylori porCDAB and oorDABC genes encode distinct pyruvate:flavodoxin and 2-oxoglutarate:acceptor oxidoreductases which mediate electron transport to NADP. J Bacteriol 180: 1119-1128.
52. Jackson, R.J., Elvers, K.T., Lee, L.J., Gidley, M.D., Wainwright, L.M., Lightfoot, J., et al. (2007) Oxygen reactivity of both respiratory oxidases in Campylobacter jejuni: the cydAB genes encode a cyanide-resistant, low-affinity oxidase that is not of the cytochrome bd type. J Bacteriol 189: 1604-1615. (Pubitemid 46446122)
53. Janssen, R., Krogfelt, K.A., Cawthraw, S.A., van Pelt, W., Wagenaar, J.A., and Owen, R.J. (2008) Host-pathogen interactions in Campylobacter infections: the host perspective. Clin Microbiol Rev 21: 505-518.
54. Jeon, B., and Zhang, Q. (2007) Cj0011c, a periplasmic single- and double-stranded DNA-binding protein, contributes to natural transformation in Campylobacter jejuni. J Bacteriol 189: 7399-7407. (Pubitemid 47557356)
55. Jeon, B., and Zhang, Q. (2009) Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter. J Antimicrob Chemother 63: 946-948.
56. Jeon, B., Muraoka, W., Sahin, O., and Zhang, Q. (2008) Role of Cj1211 in natural transformation and transfer of antibiotic resistance determinants in Campylobacter jejuni. Antimicrob Agents Chemother 52: 2699-2708.
57. Jeon, B., Muraoka, W., Scupham, A., and Zhang, Q. (2009) Roles of lipooligosaccharide and capsular polysaccharide in antimicrobial resistance and natural transformation of Campylobacter jejuni. J Antimicrob Chemother 63: 462-468.
58. Jiang, W., Hou, Y., and Inouye, M. (1997) CspA, the major cold-shock protein of Escherichia coli, is an RNA chaperone. J Biol Chem 272: 196-202.
59. Jin, S., Joe, A., Lynett, J., Hani, E.K., Sherman, P., and Chan, V.L. (2001) JlpA, a novel surface-exposed lipoprotein specific to Campylobacter jejuni, mediates adherence to host epithelial cells. Mol Microbiol 39: 1225-1236. (Pubitemid 32225133)
60. Jones, M.A., Marston, K.L., Woodall, C.A., Maskell, D.J., Linton, D., Karlyshev, A.V., et al. (2004) Adaptation of Campylobacter jejuni NCTC11168 to high-level colonization of the avian gastrointestinal tract. Infect Immun 72: 3769-3776. (Pubitemid 38821888)
61. Joshua, G.W., Guthrie-Irons, C., Karlyshev, A.V., and Wren, B.W. (2006) Biofilm formation in Campylobacter jejuni. Microbiology 152: 387-396.
62. Kakuda, T., and Dirita, V.J. (2006) Cj1496c encodes a Campylobacter jejuni glycoprotein that influences invasion of human epithelial cells and colonization of the chick gastrointestinal tract. Infect Immun 74: 4715-4723. (Pubitemid 44157259)
63. Kalmokoff, M., Lanthier, P., Tremblay, T.L., Foss, M., Lau, P.C., Sanders, G., et al. (2006) Proteomic analysis of Campylobacter jejuni 11168 biofilms reveals a role for the motility complex in biofilm formation. J Bacteriol 188: 4312-4320. (Pubitemid 43865750)
64. Kang, J., Huang, S., and Blaser, M.J. (2005) Structural and functional divergence of MutS2 from bacterial MutS1 and eukaryotic MSH4-MSH5 homologs. J Bacteriol 187: 3528-3537. (Pubitemid 40628710)
65. Karlyshev, A.V., Linton, D., Gregson, N.A., and Wren, B.W. (2002) A novel paralogous gene family involved in phase-variable flagella-mediated motility in Campylobacter jejuni. Microbiology 148: 473-480. (Pubitemid 34162790)
66. Karlyshev, A.V., Everest, P., Linton, D., Cawthraw, S., Newell, D.G., and Wren, B.W. (2004) The Campylobacter jejuni general glycosylation system is important for attachment to human epithelial cells and in the colonization of chicks. Microbiology 150: 1957-1964. (Pubitemid 38923693)
67. Karlyshev, A.V., Ketley, J.M., and Wren, B.W. (2005) The Campylobacter jejuni glycome. FEMS Microbiol Rev 29: 377-390.
68. Kelly, J., Jarrell, H., Millar, L., Tessier, L., Fiori, L.M., Lau, P.C., et al. (2006) Biosynthesis of the N-linked glycan in Campylobacter jejuni and addition onto protein through block transfer. J Bacteriol 188: 2427-2434.
69. Konkel, M.E., Garvis, S.G., Tipton, S.L., Anderson, D.E., Jr, and Cieplak, W., Jr (1997) Identification and molecular cloning of a gene encoding a fibronectin-binding protein (CadF) from Campylobacter jejuni. Mol Microbiol 24: 953-963.
70. Konkel, M.E., Kim, B.J., Rivera-Amill, V., and Garvis, S.G. (1999) Bacterial secreted proteins are required for the internaliztion of Campylobacter jejuni into cultured mammalian cells. Mol Microbiol 32: 691-701. (Pubitemid 29241511)
71. Konkel, M.E., Klena, J.D., Rivera-Amill, V., Monteville, M.R., Biswas, D., Raphael, B., and Mickelson, J. (2004) Secretion of virulence proteins from Campylobacter jejuni is dependent on a functional flagellar export apparatus. J Bacteriol 186: 3296-3303. (Pubitemid 38661524)
72. Kowarik, M., Young, N.M., Numao, S., Schulz, B.L., Hug, I., Callewaert, N., et al. (2006) Definition of the bacterial N-glycosylation site consensus sequence. EMBO J 25: 1957-1966.
73. Larsen, J.C., Szymanski, C., and Guerry, P. (2004) N-linked protein glycosylation is required for full competence in Campylobacter jejuni 81-176. J Bacteriol 186: 6508-6514. (Pubitemid 39258133)
74. Lee, L.H., Burg, E., III, Baqar, S., Bourgeois, A.L., Burr, D.H., Ewing, C.P., et al. (1999) Evaluation of a truncated recombinant flagellin subunit vaccine against Campylobacter jejuni. Infect Immun 67: 5799-5805.
75. Lin, J., and Martinez, A. (2006) Effect of efflux pump inhibitors on bile resistance and in vivo colonization of Campylobacter jejuni. J Antimicrob Chemother 58: 966-972.
76. Lin, J., Michel, L.O., and Zhang, Q. (2002) CmeABC functions as a multidrug efflux system in Campylobacter jejuni. Antimicrob Agents Chemother 46: 2124-2131. (Pubitemid 34665906)
77. Lin, J., Sahin, O., Michel, L.O., and Zhang, Q. (2003) Critical role of multidrug efflux pump CmeABC in bile resistance and in vivo colonization of Campylobacter jejuni. Infect Immun 71: 4250-4259. (Pubitemid 36919887)
78. Lin, J., Akiba, M., Sahin, O., and Zhang, Q. (2005a) CmeR functions as a transcriptional repressor for the multidrug efflux pump CmeABC in Campylobacter jejuni. Antimicrob Agents Chemother 49: 1067-1075. (Pubitemid 40327725)
79. Lin, J., Cagliero, C., Guo, B., Barton, Y.W., Maurel, M.C., Payot, S., and Zhang, Q. (2005b) Bile salts modulate expression of the CmeABC multidrug efflux pump in Campylobacter jejuni. J Bacteriol 187: 7417-7424. (Pubitemid 41507798)
80. Lin, J., Yan, M., Sahin, O., Pereira, S., Chang, Y.J., and Zhang, Q. (2007) Effect of macrolide usage on emergence of erythromycin-resistant Campylobacter isolates in chickens. Antimicrob Agents Chemother 51: 1678-1686. (Pubitemid 46744145)
81. Line, J.E., Svetoch, E.A., Eruslanov, B.V., Perelygin, V.V., Mitsevich, E.V., Mitsevich, I.P., et al. (2008) Isolation and purification of enterocin E-760 with broad antimicrobial activity against gram-positive and gram-negative bacteria. Antimicrob Agents Chemother 52: 1094-1100.
82. Linton, D., Allan, E., Karlyshev, A.V., Cronshaw, A.D., and Wren, B.W. (2002) Identification of N-acetylgalactosamine-containing glycoproteins PEB3 and CgpA in Campylobacter jejuni. Mol Microbiol 43: 497-508. (Pubitemid 34146738)
83. Linton, D., Dorrell, N., Hitchen, P.G., Amber, S., Karlyshev, A.V., Morris, H.R., et al. (2005) Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway. Mol Microbiol 55: 1695-1703. (Pubitemid 40445207)
84. Loc, C.C., Atterbury, R.J., El Shibiny, A., Connerton, P.L., Dillon, E., Scott, A., and Connerton, I.F. (2005) Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens. Appl Environ Microbiol 71: 6554-6563. (Pubitemid 43194136)
85. Luangtongkum, T., Jeon, B., Han, J., Plummer, P.J., Logue, C.M., and Zhang, Q. (2009) Antibiotic resistance in Campylobacter: molecular mechanisms and ecology of emergence, transmission and persistence. Future Microbiol 4: 189-200.
86. Luo, N., Sahin, O., Lin, J., Michel, L.O., and Zhang, Q. (2003) In vivo selection of Campylobacter isolates with high levels of fluoroquinolone resistance associated with gyrA mutations and the function of the CmeABC efflux pump. Antimicrob Agents Chemother 47: 390-394. (Pubitemid 36070393)
87. Luo, N., Pereira, S., Sahin, O., Lin, J., Huang, S., Michel, L., and Zhang, Q. (2005) Enhanced in vivo fitness of fluoroquinolone-resistant Campylobacter jejuni in the absence of antibiotic selection pressure. Proc Natl Acad Sci USA 102: 541-546. (Pubitemid 40282701)
88. McDermott, P.F., Bodeis, S.M., English, L.L., White, D.G., Walker, R.D., Zhao, S., et al. (2002) Ciprofloxacin resistance in Campylobacter jejuni evolves rapidly in chickens treated with fluoroquinolones. J Infect Dis 185: 837-840. (Pubitemid 34226213)
89. MacKichan, J.K., Gaynor, E.C., Chang, C., Cawthraw, S., Newell, D.G., Miller, J.F., and Falkow, S. (2004) The Campylobacter jejuni dccRS two-component system is required for optimal in vivo colonization but is dispensable for in vitro growth. Mol Microbiol 54: 1269-1286. (Pubitemid 39578270)
90. McSweegan, E., and Walker, R.I. (1986) Identification and characterization of two Campylobacter jejuni adhesins for cellular and mucous substrates. Infect Immun 53: 141-148. (Pubitemid 16084377)
91. Mendz, G.L., Ball, G.E., and Meek, D.J. (1997) Pyruvate metabolism in Campylobacter spp. Biochim Biophys Acta 1334: 291-302.
92. Miller, J.H. (1996) Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repair. Annu Rev Microbiol 50: 625-643.
93. Misawa, N., and Blaser, M.J. (2000) Detection and characterization of autoagglutination activity by Campylobacter jejuni. Infect Immun 68: 6168-6175.
94. Moen, B., Oust, A., Langsrud, O., Dorrell, N., Marsden, G.L., Hinds, J., et al. (2005) Explorative multifactor approach for investigating global survival mechanisms of Campylobacter jejuni under environmental conditions. Appl Environ Microbiol 71: 2086-2094. (Pubitemid 40546134)
95. Monteiro, M.A., Baqar, S., Hall, E.R., Chen, Y.H., Porter, C.K., Bentzel, D.E., et al. (2008) A capsule polysaccharide conjugate vaccine against diarrheal disease caused by Campylobacter jejuni. Infect Immun 77: 1128-1136.
96. Moss, C.W., Kai, A., Lambert, M.A., and Patton, C. (1984) Isoprenoid quinone content and cellular fatty acid composition of Campylobacter species. J Clin Microbiol 19: 772-776. (Pubitemid 14107715)
97. Murphy, C., Carroll, C., and Jordan, K.N. (2006) Environmental survival mechanisms of the foodborne pathogen Campylobacter jejuni. J Appl Microbiol 100: 623-632.
98. Myers, J.D., and Kelly, D.J. (2005) A sulphite respiration system in the chemoheterotrophic human pathogen Campylobacter jejuni. Microbiology 151: 233-242.
99. Nikaido, H. (2003) Molecular basis of bacterial outer membrane permeability revisited. Microbiol Mol Biol Rev 67: 593-656.
100. Noor, S.M., Husband, A.J., and Widders, P.R. (1995) In ovo oral vaccination with Campylobacter jejuni establishes early development of intestinal immunity in chickens. Br Poult Sci 36: 563-573.
101. Nuijten, P.J., van Asten, F.J., Gaastra, W., and van der Zeijst, B.A. (1990) Structural and functional analysis of two Campylobacter jejuni flagellin genes. J Biol Chem 265: 17798-17804. (Pubitemid 20355935)
102. Olson, C.K., Ethelberg, S., van Pelt, W., and Tauxe, R.V. (2008) Epidemiology of Campylobacter jejuni infections in industrialized nations. In Campylobacter. Nachamkin, I., Szymanski, C., and Blaser, M.J. (eds). Washington, DC, USA: ASM Press, pp. 163-189.
103. Pajaniappan, M., Hall, J.E., Cawthraw, S.A., Newell, D.G., Gaynor, E.C., Fields, J.A., et al. (2008) A temperature-regulated Campylobacter jejuni gluconate dehydrogenase is involved in respiration-dependent energy conservation and chicken colonization. Mol Microbiol 68: 474-491. (Pubitemid 351422962)
104. Palyada, K., Threadgill, D., and Stintzi, A. (2004) Iron acquisition and regulation in Campylobacter jejuni. J Bacteriol 186: 4714-4729. (Pubitemid 38891034)
105. Park, S.F., Purdy, D., and Leach, S. (2000) Localized reversible frameshift mutation in the flhA gene confers phase variability to flagellin gene expression in Campylobacter coli. J Bacteriol 182: 207-210. (Pubitemid 30004577)
106. Parker, C.T., Quinones, B., Miller, W.G., Horn, S.T., and Mandrell, R.E. (2006) Comparative genomic analysis of Campylobacter jejuni strains reveals diversity due to genomic elements similar to those present in C. jejuni strain RM1221. J Clin Microbiol 44: 4125-4135. (Pubitemid 44737259)
107. Parkhill, J., Wren, B.W., Mungall, K., Ketley, J.M., Churcher, C., Basham, D., et al. (2000) The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature 403: 665-668. (Pubitemid 30104008)
108. Patton, T.G., Scupham, A.J., Bearson, S.M., and Carlson, S.A. (2008) Characterization of fecal microbiota from a Salmonella endemic cattle herd as determined by oligonucleotide fingerprinting of rDNA genes. Vet Microbiol 136: 285-292.
109. Pei, Z., Burucoa, C., Grignon, B., Baqar, S., Huang, X.Z., Kopecko, D.J., et al. (1998) Mutation in the peb1A locus of Campylobacter jejuni reduces interactions with epithelial cells and intestinal colonization of mice. Infect Immun 66: 938-943. (Pubitemid 28101130)
110. Pittman, M.S., Elvers, K.T., Lee, L., Jones, M.A., Poole, R.K., Park, S.F., and Kelly, D.J. (2007) Growth of Campylobacter jejuni on nitrate and nitrite: electron transport to NapA and NrfA via NrfH and distinct roles for NrfA and the globin Cgb in protection against nitrosative stress. Mol Microbiol 63: 575-590. (Pubitemid 46058941)
111. Poly, F., and Guerry, P. (2008) Pathogenesis of Campylobacter. Curr Opin Gastroenterol 24: 27-31.
112. Poly, F., Ewing, C., Goon, S., Hickey, T.E., Rockabrand, D., Majam, G., et al. (2007) Heterogeneity of a Campylobacter jejuni protein that is secreted through the flagellar filament. Infect Immun 75: 3859-3867. (Pubitemid 47206283)
113. Pumbwe, L., and Piddock, L.J. (2002) Identification and molecular characterisation of CmeB, a Campylobacter jejuni multidrug efflux pump. FEMS Microbiol Lett 206: 185-189. (Pubitemid 34117617)
114. Qu, A., Brulc, J.M., Wilson, M.K., Law, B.F., Theoret, J.R., Joens, L.A., et al. (2008) Comparative metagenomics reveals host specific metavirulomes and horizontal gene transfer elements in the chicken cecum microbiome. PLoS ONE 3: e2945.
115. Ramos, J.L., Martinez-Bueno, M., Molina-Henares, A.J., Teran, W., Watanabe, K., Zhang, X., et al. (2005) The TetR family of transcriptional repressors. Microbiol Mol Biol Rev 69: 326-356.
116. Raphael, B.H., Pereira, S., Flom, G.A., Zhang, Q., Ketley, J.M., and Konkel, M.E. (2005) The Campylobacter jejuni response regulator, CbrR, modulates sodium deoxycholate resistance and chicken colonization. J Bacteriol 187: 3662-3670. (Pubitemid 40705568)
117. Reid, A.N., Pandey, R., Palyada, K., Naikare, H., and Stintzi, A. (2008) Identification of Campylobacter jejuni genes involved in the response to acidic pH and stomach transit. Appl Environ Microbiol 74: 1583-1597. (Pubitemid 351358456)
118. Rice, B.E., Rollins, D.M., Mallinson, E.T., Carr, L., and Joseph, S.W. (1997) Campylobacter jejuni in broiler chickens: colonization and humoral immunity following oral vaccination and experimental infection. Vaccine 15: 1922-1932. (Pubitemid 27504689)
119. Robinson, D.A. (1981) Infective dose of Campylobacter jejuni in milk. Br Med J (Clin Res Ed) 282: 1584.
120. Rosenquist, H., Nielsen, N.L., Sommer, H.M., Norrung, B., and Christensen, B.B. (2003) Quantitative risk assessment of human campylobacteriosis associated with thermophilic Campylobacter species in chickens. Int J Food Microbiol 83: 87-103. (Pubitemid 36379126)
121. Routh, M.D., Su, C.C., Zhang, Q., and Yu, E.W. (2009) Structures of AcrR and CmeR: insight into the mechanisms of transcriptional repression and multi-drug recognition in the TetR family of regulators. Biochim Biophys Acta 1794: 844-851.
122. Ruiz-Palacios, G.M. (2007) The health burden of Campylobacter infection and the impact of antimicrobial resistance: playing chicken. Clin Infect Dis 44: 701-703. (Pubitemid 46272981)
123. Sauer, U., and Eikmanns, B.J. (2005) The PEP-pyruvate-oxaloacetate node as the switch point for carbon flux distribution in bacteria. FEMS Microbiol Rev 29: 765-794. (Pubitemid 41149049)
124. Schaffer, C., Graninger, M., and Messner, P. (2001) Prokaryotic glycosylation. Proteomics 1: 248-261.
125. Schoeni, J.L., and Doyle, M.P. (1992) Reduction of Campylobacter jejuni colonization of chicks by cecum-colonizing bacteria producing anti-C. jejuni metabolites. Appl Environ Microbiol 58: 664-670.
126. Schoeni, J.L., and Wong, A.C. (1994) Inhibition of Campylobacter jejuni colonization in chicks by defined competitive exclusion bacteria. Appl Environ Microbiol 60: 1191-1197.
127. Scott, A.E., Timms, A.R., Connerton, P.L., El Shibiny, A., and Connerton, I.F. (2007a) Bacteriophage influence Campylobacter jejuni types populating broiler chickens. Environ Microbiol 9: 2341-2353.
128. Scott, A.E., Timms, A.R., Connerton, P.L., Loc, C.C., Adzfa, R.K., and Connerton, I.F. (2007b) Genome dynamics of Campylobacter jejuni in response to bacteriophage predation. PLoS Pathog 3: e119.
129. Scott, N.E., and Cordwell, S.J. (2009) Campylobacter proteomics: guidelines, challenges and future perspectives. Expert Rev Proteomics 6: 61-74.
130. Selby, C.P., and Sancar, A. (1994) Mechanisms of transcription-repair coupling and mutation frequency decline. Microbiol Rev 58: 317-329. (Pubitemid 24279095)
131. Sellars, M.J., Hall, S.J., and Kelly, D.J. (2002) Growth of Campylobacter jejuni supported by respiration of fumarate, nitrate, nitrite, trimethylamine-N-oxide, or dimethyl sulfoxide requires oxygen. J Bacteriol 184: 4187-4196.
132. Shoaf-Sweeney, K.D., Larson, C.L., Tang, X., and Konkel, M.E. (2008) Identification of Campylobacter jejuni proteins recognized by chicken maternal antibodies. Appl Environ Microbiol 74: 6867-6875.
133. Sizemore, D.R., Warner, B., Lawrence, J., Jones, A., and Killeen, K.P. (2006) Live, attenuated Salmonella typhimurium vectoring Campylobacter antigens. Vaccine 24: 3793-3803.
134. Smith, M.A., Finel, M., Korolik, V., and Mendz, G.L. (2000) Characteristics of the aerobic respiratory chains of the microaerophiles Campylobacter jejuni and Helicobacter pylori. Arch Microbiol 174: 1-10. (Pubitemid 30625674)
135. Song, Y.C., Jin, S., Louie, H., Ng, D., Lau, R., Zhang, Y., et al. (2004) FlaC, a protein of Campylobacter jejuni TGH9011 (ATCC43431) secreted through the flagellar apparatus, binds epithelial cells and influences cell invasion. Mol Microbiol 53: 541-553. (Pubitemid 38998174)
136. St Maurice, M., Cremades, N., Croxen, M.A., Sisson, G., Sancho, J., and Hoffman, P.S. (2007) Flavodoxin: quinone reductase (FqrB): a redox partner of pyruvate: ferredoxin oxidoreductase that reversibly couples pyruvate oxidation to NADPH production in Helicobacter pylori and Campylobacter jejuni. J Bacteriol 189: 4764-4773. (Pubitemid 47025588)
137. Stern, N.J., Svetoch, E.A., Eruslanov, B.V., Perelygin, V.V., Mitsevich, E.V., Mitsevich, I.P., et al. (2006) Isolation of a Lactobacillus salivarius strain and purification of its bacteriocin, which is inhibitory to Campylobacter jejuni in the chicken gastrointestinal system. Antimicrob Agents Chemother 50: 3111-3116.
138. Stintzi, A. (2003) Gene expression profile of Campylobacter jejuni in response to growth temperature variation. J Bacteriol 185: 2009-2016.
139. Stintzi, A., Marlow, D., Palyada, K., Naikare, H., Panciera, R., Whitworth, L., and Clarke, C. (2005) Use of genome-wide expression profiling and mutagenesis to study the intestinal lifestyle of Campylobacter jejuni. Infect Immun 73: 1797-1810. (Pubitemid 40470769)
140. Szymanski, C.M., Yao, R., Ewing, C.P., Trust, T.J., and Guerry, P. (1999) Evidence for a system of general protein glycosylation in Campylobacter jejuni. Mol Microbiol 32: 1022-1030.
141. Szymanski, C.M., Goon, S., Allan, B., and Guerry, P. (2005) Protein glycosylation in Campylobacter. In Campylobacter: Molecular and Cellular Biology. Ketley, J.M., and Konkel, M.E. (eds). Wymondham, UK: Horizon Bioscience, pp. 259-274.
142. Taboada, E.N., Acedillo, R.R., Carrillo, C.D., Findlay, W.A., Medeiros, D.T., Mykytczuk, O.L., et al. (2004) Large-scale comparative genomics meta-analysis of Campylobacter jejuni isolates reveals low level of genome plasticity. J Clin Microbiol 42: 4566-4576.
143. Taylor, D.E., De Grandis, S.A., Karmali, M.A., and Fleming, P.C. (1981) Transmissible plasmids from Campylobacter jejuni. Antimicrob Agents Chemother 19: 831-835.
144. Thibault, P., Logan, S.M., Kelly, J.F., Brisson, J.R., Ewing, C.P., Trust, T.J., and Guerry, P. (2001) Identification of the carbohydrate moieties and glycosylation motifs in Campylobacter jejuni flagellin. J Biol Chem 276: 34862-34870. (Pubitemid 37384488)
145. Vandamme, P., Dewhirst, F.E., Paster, B.J., and On, S.L. (2005) Genus I. Campylobacter. In Bergey's Manual of Systematic Bacteriology. Garrity, G., Brenner, D.J., Krieg, N.R., and Staley, J.T. (eds). New York, USA: Springer, pp. 1147-1161.
146. Velayudhan, J., and Kelly, D.J. (2002) Analysis of gluconeogenic and anaplerotic enzymes in Campylobacter jejuni: an essential role for phosphoenolpyruvate carboxykinase. Microbiology 148: 685-694. (Pubitemid 34232851)
147. Velayudhan, J., Jones, M.A., Barrow, P.A., and Kelly, D.J. (2004) L-serine catabolism via an oxygen-labile L-serine dehydratase is essential for colonization of the avian gut by Campylobacter jejuni. Infect Immun 72: 260-268. (Pubitemid 38018184)
148. van Vliet, A.H., Wooldridge, K.G., and Ketley, J.M. (1998) Iron-responsive gene regulation in a Campylobacter jejuni fur mutant. J Bacteriol 180: 5291-5298. (Pubitemid 28471523)
149. Wacker, M., Linton, D., Hitchen, P.G., Nita-Lazar, M., Haslam, S.M., North, S.J., et al. (2002) N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli. Science 298: 1790-1793. (Pubitemid 35404123)
150. Wacker, M., Feldman, M.F., Callewaert, N., Kowarik, M., Clarke, B.R., Pohl, N.L., et al. (2006) Substrate specificity of bacterial oligosaccharyltransferase suggests a common transfer mechanism for the bacterial and eukaryotic systems. Proc Natl Acad Sci USA 103: 7088-7093.
151. Wagenaar, J.A., Van Bergen, M.A., Mueller, M.A., Wassenaar, T.M., and Carlton, R.M. (2005) Phage therapy reduces Campylobacter jejuni colonization in broilers. Vet Microbiol 109: 275-283. (Pubitemid 41073509)
152. Wassenaar, T.M., Bleumink-Pluym, N.M., and van der Zeijst, B.A. (1991) Inactivation of Campylobacter jejuni flagellin genes by homologous recombination demonstrates that flaA but not flaB is required for invasion. EMBO J 10: 2055-2061.
153. Wassenaar, T.M., van der Zeijst, B.A., Ayling, R., and Newell, D.G. (1993) Colonization of chicks by motility mutants of Campylobacter jejuni demonstrates the importance of flagellin A expression. J Gen Microbiol 139: 1171-1175. (Pubitemid 23212240)
154. Weerakoon, D.R., and Olson, J.W. (2008) The Campylobacter jejuni NADH: ubiquinone oxidoreductase (complex I) utilizes flavodoxin rather than NADH. J Bacteriol 190: 915-925.
155. Weingarten, R.A., Grimes, J.L., and Olson, J.W. (2008) Role of Campylobacter jejuni respiratory oxidases and reductases in host colonization. Appl Environ Microbiol 74: 1367-1375. (Pubitemid 351358431)
156. White, D. (2007) Bioenergetics in the cytosol. In The Physiology and Biochemistry of Prokaryotes. White, D. (ed.). New York, USA: Oxford University Press, pp. 181-195.
157. Wiesner, R.S., Hendrixson, D.R., and Dirita, V.J. (2003) Natural transformation of Campylobacter jejuni requires components of a type II secretion system. J Bacteriol 185: 5408-5418.
158. Woodall, C.A., Jones, M.A., Barrow, P.A., Hinds, J., Marsden, G.L., Kelly, D.J., et al. (2005) Campylobacter jejuni gene expression in the chick cecum: evidence for adaptation to a low-oxygen environment. Infect Immun 73: 5278-5285. (Pubitemid 41105697)
159. Wösten, M.M., Wagenaar, J.A., and van Putten, J.P. (2004) The FlgS/FlgR two-component signal transduction system regulates the fla regulon in Campylobacter jejuni. J Biol Chem 279: 16214-16222.
160. Wright, J.A., Grant, A.J., Hurd, D., Harrison, M., Guccione, E.J., Kelly, D.J., and Maskell, D.J. (2009) Metabolite and transcriptome analysis of Campylobacter jejuni in vitro growth reveals a stationary-phase physiological switch. Microbiology 155: 80-94.
161. Wyszynska, A., Raczko, A., Lis, M., and Jagusztyn-Krynicka, E.K. (2004) Oral immunization of chickens with avirulent Salmonella vaccine strain carrying C. jejuni 72Dz/92 cjaA gene elicits specific humoral immune response associated with protection against challenge with wild-type Campylobacter. Vaccine 22: 1379-1389. (Pubitemid 38446914)
162. Yan, M., Sahin, O., Lin, J., and Zhang, Q. (2006) Role of the CmeABC efflux pump in the emergence of fluoroquinolone-resistant Campylobacter under selection pressure. J Antimicrob Chemother 58: 1154-1159. (Pubitemid 44884133)
163. Young, K.T., Davis, L.M., and Dirita, V.J. (2007) Campylobacter jejuni: molecular biology and pathogenesis. Nat Rev Microbiol 5: 665-679.
164. Zhang, Q., and Plummer, P.J. (2008) Mechanisms of antibiotic resistance in Campylobacter jejuni. In Campylobacter. Nachamkin, I., Szymanski, C., and Blaser, M.J. (eds). Washington, DC, USA: ASM Press, pp. 263-276.
165. Zilbauer, M., Dorrell, N., Wren, B.W., and Bajaj-Elliott, M. (2008) Campylobacter jejuni-mediated disease pathogenesis: an update. Trans R Soc Trop Med Hyg 102: 123-129.
166. Ziprin, R.L., Young, C.R., Stanker, L.H., Hume, M.E., and Konkel, M.E. (1999) The absence of cecal colonization of chicks by a mutant of Campylobacter jejuni not expressing bacterial fibronectin-binding protein. Avian Dis 43: 586-589.
167. de Zoete, M.R., van Putten, J.P., and Wagenaar, J.A. (2007) Vaccination of chickens against Campylobacter. Vaccine 25: 5548-5557.