-
1
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002; 16:6-21.
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
2
-
-
0037224722
-
DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells
-
Robert MF, Morin S, Beaulieu N, Gauthier F, Chute IC, Barsalou A, MacLeod AR. DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. Nat Genet 2003; 33:61-5.
-
(2003)
Nat Genet
, vol.33
, pp. 61-65
-
-
Robert, M.F.1
Morin, S.2
Beaulieu, N.3
Gauthier, F.4
Chute, I.C.5
Barsalou, A.6
MacLeod, A.R.7
-
3
-
-
0033988813
-
DNA methyltransferase Dnmt1 associates with histone deacetylase activity
-
Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T. DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat Genet 2000; 24:88-91.
-
(2000)
Nat Genet
, vol.24
, pp. 88-91
-
-
Fuks, F.1
Burgers, W.A.2
Brehm, A.3
Hughes-Davies, L.4
Kouzarides, T.5
-
4
-
-
0033919595
-
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
-
Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL, Wolffe AP. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat Genet 2000; 25:338-42.
-
(2000)
Nat Genet
, vol.25
, pp. 338-342
-
-
Robertson, K.D.1
Ait-Si-Ali, S.2
Yokochi, T.3
Wade, P.A.4
Jones, P.L.5
Wolffe, A.P.6
-
5
-
-
0031684108
-
Effect of aphidicolin on DNA methyltransferase in the nucleus
-
Suetake I, Kano Y, Tajima S. Effect of aphidicolin on DNA methyltransferase in the nucleus. Cell Struct Funct 1998; 23:137-42.
-
(1998)
Cell Struct Funct
, vol.23
, pp. 137-142
-
-
Suetake, I.1
Kano, Y.2
Tajima, S.3
-
6
-
-
0034658196
-
Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells
-
Robertson KD, Keyomarsi K, Gonzales FA, Velicescu M, Jones PA. Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells. Nucleic Acids Res 2000; 28:2108-13.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 2108-2113
-
-
Robertson, K.D.1
Keyomarsi, K.2
Gonzales, F.A.3
Velicescu, M.4
Jones, P.A.5
-
7
-
-
0029994420
-
Differentiating mouse myoblasts DNA methyltransferase is posttranscriptionally and posttranslationally regulated
-
Liu Y, Sun L, Jost JP. In differentiating mouse myoblasts DNA methyltransferase is posttranscriptionally and posttranslationally regulated. Nucleic Acids Res 1996; 24:2718-22.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 2718-2722
-
-
Liu, Y.1
Sun, L.2
Jost, J.P.3
-
8
-
-
32044467674
-
Differential and epigenetic gene expression profiling identifies frequent disruption of the RELN pathway in pancreatic cancers
-
Sato N, Fukushima N, Chang R, Matsubayashi H, Goggins M. Differential and epigenetic gene expression profiling identifies frequent disruption of the RELN pathway in pancreatic cancers. Gastroenterology 2006; 130:548-65.
-
(2006)
Gastroenterology
, vol.130
, pp. 548-565
-
-
Sato, N.1
Fukushima, N.2
Chang, R.3
Matsubayashi, H.4
Goggins, M.5
-
9
-
-
0042674172
-
Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma
-
Sato N, Maitra A, Fukushima N, van Heek NT, Matsubayashi H, Iacobuzio-Donahue CA, et al. Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma. Cancer Res 2003; 63:4158-66.
-
(2003)
Cancer Res
, vol.63
, pp. 4158-4166
-
-
Sato, N.1
Maitra, A.2
Fukushima, N.3
Van Heek, N.T.4
Matsubayashi, H.5
Iacobuzio-Donahue, C.A.6
-
10
-
-
0037742210
-
Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays
-
Sato N, Fukushima N, Maitra A, Matsubayashi H, Yeo CJ, Cameron JL, et al. Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays. Cancer Res 2003; 63:3735-42.
-
(2003)
Cancer Res
, vol.63
, pp. 3735-3742
-
-
Sato, N.1
Fukushima, N.2
Maitra, A.3
Matsubayashi, H.4
Yeo, C.J.5
Cameron, J.L.6
-
11
-
-
33746329002
-
Epigenetic alterations in intraductal papillary mucinous neoplasms of the pancreas
-
Sato N, Goggins M. Epigenetic alterations in intraductal papillary mucinous neoplasms of the pancreas. J Hepatobiliary Pancreat Surg 2006; 13:280-5.
-
(2006)
J Hepatobiliary Pancreat Surg
, vol.13
, pp. 280-285
-
-
Sato, N.1
Goggins, M.2
-
12
-
-
33746365858
-
The role of epigenetic alterations in pancreatic cancer
-
Sato N, Goggins M. The role of epigenetic alterations in pancreatic cancer. J Hepatobiliary Pancreat Surg 2006; 13:286-95.
-
(2006)
J Hepatobiliary Pancreat Surg
, vol.13
, pp. 286-295
-
-
Sato, N.1
Goggins, M.2
-
13
-
-
27644466889
-
Epigenetic downregulation of CDKN1C/ p57KIP2 in pancreatic ductal neoplasms identified by gene expression profiling
-
Sato N, Matsubayashi H, Abe T, Fukushima N, Goggins M. Epigenetic downregulation of CDKN1C/ p57KIP2 in pancreatic ductal neoplasms identified by gene expression profiling. Clin Cancer Res 2005; 11:4681-8.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4681-4688
-
-
Sato, N.1
Matsubayashi, H.2
Abe, T.3
Fukushima, N.4
Goggins, M.5
-
14
-
-
0036097181
-
Preproenkephalin and p16 gene CpG island hypermethylation in pancreatic intraepithelial neoplasia (PanIN) and pancreatic ductal adenocarcinoma
-
Fukushima N, Sato N, Ueki T, Rosty C, Walter KM, Yeo CJ, Hruban RHMG. Preproenkephalin and p16 gene CpG island hypermethylation in pancreatic intraepithelial neoplasia (PanIN) and pancreatic ductal adenocarcinoma. Am J Pathol 2002; 160:1573-81.
-
(2002)
Am J Pathol
, vol.160
, pp. 1573-1581
-
-
Fukushima, N.1
Sato, N.2
Ueki, T.3
Rosty, C.4
Walter, K.M.5
Yeo, C.J.6
Rhmg, H.7
-
15
-
-
0036305839
-
Aberrant methylation of CpG islands in intraductal papillary mucinous neoplasms of the pancreas increases with histological grade
-
Sato N, Ueki T, Fukushima N, Iacobuzio-Donahue CA, Yeo CJ, Cameron JL, Hruban RHMG. Aberrant methylation of CpG islands in intraductal papillary mucinous neoplasms of the pancreas increases with histological grade. Gastroenterology 2002; 123:1365-72.
-
(2002)
Gastroenterology
, vol.123
, pp. 1365-1372
-
-
Sato, N.1
Ueki, T.2
Fukushima, N.3
Iacobuzio-Donahue, C.A.4
Yeo, C.J.5
Cameron, J.L.6
Hruban, R.H.M.G.7
-
16
-
-
39749128967
-
CpG island methylation profile of pancreatic intraepithelial neoplasia
-
Sato NFN, Hruban RH, Goggins M. CpG island methylation profile of pancreatic intraepithelial neoplasia. Mod Pathol 2007; 21:238-44.
-
(2007)
Mod Pathol
, vol.21
, pp. 238-244
-
-
Sato, N.F.N.1
Hruban, R.H.2
Goggins, M.3
-
17
-
-
0028001087
-
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
-
DOI 10.1038/ng0894-536
-
Issa JP, Ottaviano YL, Celano P, Hamilton SR, Davidson NE, Baylin SB. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat Genet 1994; 7:536-40. (Pubitemid 24308343)
-
(1994)
Nature Genetics
, vol.7
, Issue.4
, pp. 536-540
-
-
Issa, J.-P.J.1
Ottaviano, Y.L.2
Celano, P.3
Hamilton, S.R.4
Davidson, N.E.5
Baylin, S.B.6
-
18
-
-
23644457453
-
Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes
-
DOI 10.1016/S1542-3565(05)00359-9, PII S1542356505003599
-
Matsubayashi H, Skinner H, Iacobuzio-Donahue C, Abe T, Sato N, Riall TS, et al. Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes. Clin Gastro Hepatol 2005; 3:752-60. (Pubitemid 41116727)
-
(2005)
Clinical Gastroenterology and Hepatology
, vol.3
, Issue.8
, pp. 752-760
-
-
Matsubayashi, H.1
Skinner, H.G.2
Iacobuzio-Donahue, C.3
Abe, T.4
Sato, N.5
Riall, T.S.6
Yeo, C.J.7
Kern, S.E.8
Goggins, M.9
-
19
-
-
12244255359
-
Age- And disease-related methylation of multiple genes in nonneoplastic duodenum and in duodenal juice
-
Matsubayashi H, Sato N, Brune K, Blackford AL, Hruban RH, Canto M, et al. Age- and disease-related methylation of multiple genes in non-neoplastic duodenal tissues. Clin Cancer Res 2005; 11:573-83. (Pubitemid 40116882)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.2 I
, pp. 573-583
-
-
Matsubayashi, H.1
Sato, N.2
Brune, K.3
Blackford, A.L.4
Hruban, R.H.5
Canto, M.6
Yeo, C.J.7
Goggins, M.8
-
20
-
-
0038527642
-
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor
-
DOI 10.1126/science.1065173
-
Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, Faretta M, et al. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 2002; 295:1079-82. (Pubitemid 34132239)
-
(2002)
Science
, vol.295
, Issue.5557
, pp. 1079-1082
-
-
Di Croce, L.1
Raker, V.A.2
Corsaro, M.3
Fazi, F.4
Fanelli, M.5
Faretta, M.6
Fuks, F.7
Lo Coco, F.8
Kouzarides, T.9
Nervi, C.10
Minucci, S.11
Pelicci, P.G.12
-
21
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga MF, Ballestar E, Paz MF, Ropero S, Setien F, Ballestar ML, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 2005; 102:10604-9.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10604-10609
-
-
Fraga, M.F.1
Ballestar, E.2
Paz, M.F.3
Ropero, S.4
Setien, F.5
Ballestar, M.L.6
-
22
-
-
0033563083
-
CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression
-
Eads CA, Danenberg KD, Kawakami K, Saltz LB, Danenberg PV, Laird PW. CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. Cancer Res 1999; 59:2302-6.
-
(1999)
Cancer Res
, vol.59
, pp. 2302-2306
-
-
Eads, C.A.1
Danenberg, K.D.2
Kawakami, K.3
Saltz, L.B.4
Danenberg, P.V.5
Laird, P.W.6
-
23
-
-
0036186811
-
DNA methyltransferase and demethylase in human prostate cancer
-
DOI 10.1002/mc.10033
-
Patra SK, Patra A, Zhao H, Dahiya R. DNA methyltransferase and demethylase in human prostate cancer. Mol Carcinog 2002; 33:163-71. (Pubitemid 34195197)
-
(2002)
Molecular Carcinogenesis
, vol.33
, Issue.3
, pp. 163-171
-
-
Patra, S.K.1
Patra, A.2
Zhao, H.3
Dahiya, R.4
-
24
-
-
0037598752
-
Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas
-
DOI 10.1002/ijc.11127
-
Saito Y, Kanai Y, Nakagawa T, Sakamoto M, Saito H, Ishii H, Hirohashi S. Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas. Int J Cancer 2003; 105:527-32. (Pubitemid 36578558)
-
(2003)
International Journal of Cancer
, vol.105
, Issue.4
, pp. 527-532
-
-
Saito, Y.1
Kanai, Y.2
Nakagawa, T.3
Sakamoto, M.4
Saito, H.5
Ishi, H.6
Hirohashi, S.7
-
25
-
-
0141995080
-
Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas
-
Girault I, Tozlu S, Lidereau R, Bieche I. Expression analysis of DNA methyltransferases 1, 3A and 3B in sporadic breast carcinomas. Clin Cancer Res 2003; 9:4415-22. (Pubitemid 37248399)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.12
, pp. 4415-4422
-
-
Girault, I.1
Tozlu, S.2
Lidereau, R.3
Bieche, I.4
-
26
-
-
0033555953
-
Role of DNA 5-methylcytosine transferase in cell transformation by fos
-
Bakin AV, Curran T. Role of DNA 5-methylcytosine transferase in cell transformation by fos. Science 1999; 283:387-90. (Pubitemid 129501100)
-
(1999)
Science
, vol.283
, Issue.5400
, pp. 387-390
-
-
Bakin, A.V.1
Curran, T.2
-
27
-
-
51049117752
-
Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells
-
Zhou Q, Agoston AT, Atadja P, Nelson WG, Davidson NE. Inhibition of histone deacetylases promotes ubiquitin- dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells. Mol Cancer Res 2008; 6:873-83.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 873-883
-
-
Zhou, Q.1
Agoston, A.T.2
Atadja, P.3
Nelson, W.G.4
Davidson, N.E.5
-
28
-
-
24044493602
-
Increased protein stability causes DNA methyltransferase 1 dysregulation in breast cancer
-
DOI 10.1074/jbc.M501675200
-
Agoston AT, Argani P, Yegnasubramanian S, De Marzo AM, Ansari-Lari MA, Hicks JL, et al. Increased protein stability causes DNA methyltransferase 1 dysregulation in breast cancer. J Biol Chem 2005; 280:18302-10. (Pubitemid 41389076)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.18
, pp. 18302-18310
-
-
Agoston, A.T.1
Argani, P.2
Yegnasubramanian, S.3
De Marzo, A.M.4
Ansari-Lari, M.A.5
Hicks, J.L.6
Davidson, N.E.7
Nelson, W.G.8
-
29
-
-
26444473234
-
Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis
-
DOI 10.1073/pnas.0506612102
-
Yamada Y, Jackson-Grusby L, Linhart H, Meissner A, Eden A, Lin H, Jaenisch R. Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. Proc Natl Acad Sci USA 2005; 102:13580-5. (Pubitemid 41420891)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.38
, pp. 13580-13585
-
-
Yamada, Y.1
Jackson-Grusby, L.2
Linhart, H.3
Meissner, A.4
Eden, A.5
Lin, H.6
Jaenisch, R.7
-
30
-
-
23644457453
-
Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes
-
DOI 10.1016/S1542-3565(05)00359-9, PII S1542356505003599
-
Matsubayashi H, Skinner HG, Iacobuzio-Donahue C, Abe T, Sato N, Riall TS, et al. Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes. Clin Gastroenterol Hepatol 2005; 3:752-60. (Pubitemid 41116727)
-
(2005)
Clinical Gastroenterology and Hepatology
, vol.3
, Issue.8
, pp. 752-760
-
-
Matsubayashi, H.1
Skinner, H.G.2
Iacobuzio-Donahue, C.3
Abe, T.4
Sato, N.5
Riall, T.S.6
Yeo, C.J.7
Kern, S.E.8
Goggins, M.9
-
31
-
-
0033577229
-
Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers
-
Stolzenberg-Solomon RZ, Albanes D, Nieto FJ, Hartman TJ, Tangrea JA, Rautalahti M, et al. Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers. J Natl Cancer Inst 1999; 91:535-41. (Pubitemid 29157062)
-
(1999)
Journal of the National Cancer Institute
, vol.91
, Issue.6
, pp. 535-541
-
-
Stolzenberg-Solomon, R.Z.1
Albanes, D.2
Nieto, F.J.3
Hartman, T.J.4
Tangrea, J.A.5
Rautalahti, M.6
Sehlub, J.7
Virtamo, J.8
Taylor, P.R.9
-
32
-
-
0035313096
-
Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers
-
DOI 10.1093/aje/153.7.680
-
Stolzenberg-Solomon RZ, Pietinen P, Barrett MJ, Taylor PR, Virtamo J, Albanes D. Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers. Am J Epidemiol 2001; 153:680-7. (Pubitemid 32250976)
-
(2001)
American Journal of Epidemiology
, vol.153
, Issue.7
, pp. 680-687
-
-
Stolzenberg-Solomon, R.Z.1
Pietinen, P.2
Barrett, M.J.3
Taylor, P.R.4
Virtamo, J.5
Albanes, D.6
-
33
-
-
0034720284
-
CpG methylation is maintained in human cancer cells lacking DNMT1
-
DOI 10.1038/35010000
-
Rhee I, Jair KW, Yen RW, Lengauer C, Herman JG, Kinzler KW, et al. CpG methylation is maintained in human cancer cells lacking DNMT1. Nature 2000; 404:1003-7. (Pubitemid 30243595)
-
(2000)
Nature
, vol.404
, Issue.6781
, pp. 1003-1007
-
-
Rhee, I.1
Jalr, K.-W.2
Yen, R.-W.C.3
Lengauer, C.4
Herman, J.G.5
Kinzler, K.W.6
Vogelstein, B.7
Baylin, S.B.8
Schuebel, K.E.9
-
34
-
-
33847293264
-
Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
-
DOI 10.1038/ng1982, PII NG1982
-
Chen T, Hevi S, Gay F, Tsujimoto N, He T, Zhang B, et al. Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells. Nat Genet 2007; 39:391-6. (Pubitemid 46328497)
-
(2007)
Nature Genetics
, vol.39
, Issue.3
, pp. 391-396
-
-
Chen, T.1
Hevi, S.2
Gay, F.3
Tsujimoto, N.4
He, T.5
Zhang, B.6
Ueda, Y.7
Li, E.8
-
35
-
-
0028151343
-
Toxicity of 5-aza-2′- Deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
-
Juttermann R, Li E, Jaenisch R. Toxicity of 5-aza-2′- deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc Natl Acad Sci USA 1994; 91:11797-801.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11797-11801
-
-
Juttermann, R.1
Li, E.2
Jaenisch, R.3
-
36
-
-
0037093195
-
Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome a study of the cancer and leukemia group B
-
Silverman LR, Demakos EP, Peterson BL, Kornblith AB, Holland JC, Odchimar-Reissig R, et al. Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B. J Clin Oncol 2002; 20:2429-40.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2429-2440
-
-
Silverman, L.R.1
Demakos, E.P.2
Peterson, B.L.3
Kornblith, A.B.4
Holland, J.C.5
Odchimar-Reissig, R.6
-
37
-
-
0345275879
-
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
-
Fang MZ, Wang Y, Ai N, Hou Z, Sun Y, Lu H, et al. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 2003; 63:7563-70.
-
(2003)
Cancer Res
, vol.63
, pp. 7563-7570
-
-
Fang, M.Z.1
Wang, Y.2
Ai, N.3
Hou, Z.4
Sun, Y.5
Lu, H.6
-
38
-
-
25144507259
-
Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids
-
Lee WJ, Shim JY, Zhu BT. Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids. Mol Pharmacol 2005; 68:1018-30.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 1018-1030
-
-
Lee, W.J.1
Shim, J.Y.2
Zhu, B.T.3
-
39
-
-
19844374460
-
Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells
-
Qanungo S, Das M, Haldar S, Basu A. Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells. Carcinogenesis 2005; 26:958-67.
-
(2005)
Carcinogenesis
, vol.26
, pp. 958-967
-
-
Qanungo, S.1
Das, M.2
Haldar, S.3
Basu, A.4
-
40
-
-
0033153303
-
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
-
Robertson KD, Uzvolgyi E, Liang G, Talmadge C, Sumegi J, Gonzales FA, Jones PA. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res 1999; 27:2291-8.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 2291-2298
-
-
Robertson, K.D.1
Uzvolgyi, E.2
Liang, G.3
Talmadge, C.4
Sumegi, J.5
Gonzales, F.A.6
Jones, P.A.7
-
41
-
-
0033566973
-
Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis
-
De Marzo AM, Marchi VL, Yang ES, Veeraswamy R, Lin X, Nelson WG. Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis. Cancer Res 1999; 59:3855-60.
-
(1999)
Cancer Res
, vol.59
, pp. 3855-3860
-
-
De Marzo, A.M.1
Marchi, V.L.2
Yang, E.S.3
Veeraswamy, R.4
Lin, X.5
Nelson, W.G.6
-
42
-
-
35548953686
-
An elaborate pathway required for Ras-mediated epigenetic silencing
-
DOI 10.1038/nature06251, PII NATURE06251
-
Gazin C, Wajapeyee N, Gobeil S, Virbasius CM, Green MR. An elaborate pathway required for Ras-mediated epigenetic silencing. Nature 2007; 449:1073-7. (Pubitemid 350014604)
-
(2007)
Nature
, vol.449
, Issue.7165
, pp. 1073-1077
-
-
Gazin, C.1
Wajapeyee, N.2
Gobeil, S.3
Virbasius, C.-M.4
Green, M.R.5
-
43
-
-
0027733796
-
K-ras oncogene activation in adenocarcinomas of the human pancreas: A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization
-
Hruban RH, van Mansfeld ADM, Offerhaus GJA, van Weering DHJ, Allison DC, Goodman SN, et al. K-ras oncogene activation in adenocarcinomas of the human pancreas: a study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization. Am J Pathol 1993; 143:545-54.
-
(1993)
Am J Pathol
, vol.143
, pp. 545-554
-
-
Hruban, R.H.1
Van Mansfeld, A.D.M.2
Offerhaus, G.J.A.3
Van Weering, D.H.J.4
Allison, D.C.5
Goodman, S.N.6
-
44
-
-
33748056792
-
Detailed pathologic evaluation of non-invasive precursor lesions of the pancreas in patients with a strong family history of pancreatic cancer
-
Brune K, Goggins M, O'Mailey L, Abe T, Canto M, Klein A, et al. Detailed pathologic evaluation of non-invasive precursor lesions of the pancreas in patients with a strong family history of pancreatic cancer. Am J Surg Pathol 2006; 30:1067-76.
-
(2006)
Am J Surg Pathol
, vol.30
, pp. 1067-1076
-
-
Brune, K.1
Goggins, M.2
O'Mailey, L.3
Abe, T.4
Canto, M.5
Klein, A.6
-
45
-
-
0028222269
-
Detection of K-ras mutations in mucinous pancreatic duct hyperplasia from a patient with a family history of pancreatic carcinoma
-
DiGiuseppe JA, Hruban RH, Offerhaus GJ, Clement MJ, van den Berg FM, Cameron JL, van Mansfeld AD. Detection of K-ras mutations in mucinous pancreatic duct hyperplasia from a patient with a family history of pancreatic carcinoma. Am J of Pathol 1994; 144:889-95.
-
(1994)
Am J of Pathol
, vol.144
, pp. 889-895
-
-
DiGiuseppe, J.A.1
Hruban, R.H.2
Offerhaus, G.J.3
Clement, M.J.4
Van Den Berg, F.M.5
Cameron, J.L.6
Van Mansfeld, A.D.7
-
46
-
-
56649085104
-
Multiple genes are hypermethylated in intraductal papillary mucinous neoplasms of the pancreas
-
Hong SM, Kelly D, Griffith M, Omura N, Li A, Li CP, et al. Multiple genes are hypermethylated in intraductal papillary mucinous neoplasms of the pancreas. Modern Path 2008; 21:1499-507.
-
(2008)
Modern Path
, vol.21
, pp. 1499-1507
-
-
Hong, S.M.1
Kelly, D.2
Griffith, M.3
Omura, N.4
Li, A.5
Li, C.P.6
-
47
-
-
39749128967
-
CpG island methylation profile of pancreatic intraepithelial neoplasia
-
DOI 10.1038/modpathol.3800991, PII 3800991
-
Sato N, Fukushima N, Hruban RH, Goggins M. CpG island methylation profile of pancreatic intraepithelial neoplasia. Mod Pathol 2008; 21:238-44. (Pubitemid 351304281)
-
(2008)
Modern Pathology
, vol.21
, Issue.3
, pp. 238-244
-
-
Sato, N.1
Fukushima, N.2
Hruban, R.H.3
Goggins, M.4
-
48
-
-
41149156431
-
Genome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays
-
DOI 10.1038/sj.onc.1210832, PII 1210832
-
Harada T, Chelala C, Bhakta V, Chaplin T, Caulee K, Baril P, et al. Genome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays. Oncogene 2008; 27:1951-60. (Pubitemid 351430826)
-
(2008)
Oncogene
, vol.27
, Issue.13
, pp. 1951-1960
-
-
Harada, T.1
Chelala, C.2
Bhakta, V.3
Chaplin, T.4
Caulee, K.5
Baril, P.6
Young, B.D.7
Lemoine, N.R.8
-
49
-
-
33748057487
-
Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays
-
DOI 10.1158/0008-5472.CAN-06-0721
-
Calhoun ES, Hucl T, Gallmeier E, West KM, Arking DE, Maitra A, et al. Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays. Cancer Res 2006; 66:7920-8. (Pubitemid 44299154)
-
(2006)
Cancer Research
, vol.66
, Issue.16
, pp. 7920-7928
-
-
Calhoun, E.S.1
Hucl, T.2
Gallmeier, E.3
West, K.M.4
Arking, D.E.5
Maitra, A.6
Iacobuzio-Donahue, C.A.7
Chakravarti, A.8
Hruban, R.H.9
Kern, S.E.10
-
50
-
-
33748669269
-
High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation
-
DOI 10.1038/sj.onc.1209570, PII 1209570
-
Pole JC, Courtay-Cahen C, Garcia MJ, Blood KA, Cooke SL, Alsop AE, et al. High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation. Oncogene 2006; 25:5693-706. (Pubitemid 44387624)
-
(2006)
Oncogene
, vol.25
, Issue.41
, pp. 5693-5706
-
-
Pole, J.C.M.1
Courtay-Cahen, C.2
Garcia, M.J.3
Blood, K.A.4
Cooke, S.L.5
Alsop, A.E.6
Tse, D.M.L.7
Caldas, C.8
Edwards, P.A.W.9
-
51
-
-
35948976564
-
Genome-wide allelotypes of familial pancreatic adenocarcinomas and familial and sporadic intraductal papillary mucinous neoplasms
-
DOI 10.1158/1078-0432.CCR-07-0471
-
Abe T, Fukushima N, Brune K, Boehm C, Sato N, Matsubayashi H, et al. Genome-wide allelotypes of familial pancreatic adenocarcinomas and familial and sporadic intraductal papillary mucinous neoplasms. Clin Cancer Res 2007; 13:6019-25. (Pubitemid 350075057)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.20
, pp. 6019-6025
-
-
Abe, T.1
Fukushima, N.2
Brune, K.3
Boehm, C.4
Sato, N.5
Matsubayashi, H.6
Canto, M.7
Petersen, G.M.8
Hruban, R.H.9
Goggins, M.10
-
52
-
-
34548678180
-
Chromosomal abnormalities of adenocarcinoma of the pancreas: Identifying early and late changes
-
DOI 10.1016/j.cancergencyto.2007.06.004, PII S0165460807003810
-
Kowalski J, Morsberger LA, Blackford A, Hawkins A, Yeo CJ, Hruban RH, Griffin CA. Chromosomal abnormalities of adenocarcinoma of the pancreas: identifying early and late changes. Cancer Genet Cytogenet 2007; 178:26-35. (Pubitemid 47419041)
-
(2007)
Cancer Genetics and Cytogenetics
, vol.178
, Issue.1
, pp. 26-35
-
-
Kowalski, J.1
Morsberger, L.A.2
Blackford, A.3
Hawkins, A.4
Yeo, C.J.5
Hruban, R.H.6
Griffin, C.A.7
-
53
-
-
33750317308
-
Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: A model for patient classification to aid fluoropyrimidine therapy
-
Brody JR, Hucl T, Gallmeier E, Winter JM, Kern SE, Murphy KM. Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: a model for patient classification to aid fluoropyrimidine therapy. Cancer Res 2006; 66:9369-73.
-
(2006)
Cancer Res
, vol.66
, pp. 9369-9373
-
-
Brody, J.R.1
Hucl, T.2
Gallmeier, E.3
Winter, J.M.4
Kern, S.E.5
Murphy, K.M.6
-
54
-
-
10744229498
-
Large-scale allelotype of pancreaticobiliary carcinoma provides quantitative estimates of genome-wide allelic loss
-
Iacobuzio-Donahue CA, van der Heijden MS, Baumgartner MR, Troup WJ, Romm JM, Doheny K, et al. Large-scale allelotype of pancreaticobiliary carcinoma provides quantitative estimates of genome-wide allelic loss. Cancer Res 2004; 64:871-5.
-
(2004)
Cancer Res
, vol.64
, pp. 871-875
-
-
Iacobuzio-Donahue, C.A.1
Van Der Heijden, M.S.2
Baumgartner, M.R.3
Troup, W.J.4
Romm, J.M.5
Doheny, K.6
-
55
-
-
33748057487
-
Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays
-
Calhoun ES, Hucl T, Gallmeier E, West KM, Arking DE, Maitra A, et al. Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays. Cancer Res 2006; 66:7920-8.
-
(2006)
Cancer Res
, vol.66
, pp. 7920-7928
-
-
Calhoun, E.S.1
Hucl, T.2
Gallmeier, E.3
West, K.M.4
Arking, D.E.5
Maitra, A.6
-
56
-
-
34250889432
-
Retinoblastoma pathway dysregulation causes DNA methyltransferase 1 overexpression in cancer via MAD2-mediated inhibition of the anaphase-promoting complex
-
Agoston AT, Argani P, De Marzo AM, Hicks JL, Nelson WG. Retinoblastoma pathway dysregulation causes DNA methyltransferase 1 overexpression in cancer via MAD2-mediated inhibition of the anaphase-promoting complex. Am J Pathol 2007; 170:1585-93.
-
(2007)
Am J Pathol
, vol.170
, pp. 1585-1593
-
-
Agoston, A.T.1
Argani, P.2
De Marzo, A.M.3
Hicks, J.L.4
Nelson, W.G.5
-
57
-
-
55149093212
-
DNA methylation alterations in endoscopic retrograde cholangiopancreatography brush samples of patients with suspected pancreaticobiliary disease
-
Parsi MA, Li A, Li CP, Goggins M. DNA methylation alterations in endoscopic retrograde cholangiopancreatography brush samples of patients with suspected pancreaticobiliary disease. Clin Gastroenterol Hepatol 2008; 6:1270-8.
-
(2008)
Clin Gastroenterol Hepatol
, vol.6
, pp. 1270-1278
-
-
Parsi, M.A.1
Li, A.2
Li, C.P.3
Goggins, M.4
-
58
-
-
57449111916
-
Genetic and epigenetic alterations of familial pancreatic cancers
-
Brune K, Hong SM, Li A, Yachida S, Abe T, Griffith M, et al. Genetic and epigenetic alterations of familial pancreatic cancers. Cancer Epidemiol Biomarkers Prev 2008; 17:3536-42.
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 3536-3542
-
-
Brune, K.1
Hong, S.M.2
Li, A.3
Yachida, S.4
Abe, T.5
Griffith, M.6
-
59
-
-
12244255359
-
Age- and disease-related methylation of multiple genes in nonneoplastic duodenum and in duodenal juice
-
Matsubayashi H, Sato N, Brune K, Blackford AL, Hruban RH, Canto M, et al. Age- and disease-related methylation of multiple genes in nonneoplastic duodenum and in duodenal juice. Clin Cancer Res 2005; 11:573-83.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 573-583
-
-
Matsubayashi, H.1
Sato, N.2
Brune, K.3
Blackford, A.L.4
Hruban, R.H.5
Canto, M.6
-
60
-
-
18944383889
-
5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal
-
Ghoshal K, Datta J, Majumder S, Bai S, Kutay H, Motiwala T, Jacob ST. 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal. Mol Cell Biol 2005; 25:4727-41.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4727-4741
-
-
Ghoshal, K.1
Datta, J.2
Majumder, S.3
Bai, S.4
Kutay, H.5
Motiwala, T.6
Jacob, S.T.7
-
61
-
-
1642499364
-
Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells
-
Cheng JC, Weisenberger DJ, Gonzales FA, Liang G, Xu GL, Hu YG, et al. Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells. Mol Cell Biol 2004; 24:1270-8.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1270-1278
-
-
Cheng, J.C.1
Weisenberger, D.J.2
Gonzales, F.A.3
Liang, G.4
Xu, G.L.5
Hu, Y.G.6
-
62
-
-
33747339752
-
Overcoming resistance to interferon- induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation
-
Reu FJ, Bae SI, Cherkassky L, Leaman DW, Lindner D, Beaulieu N, et al. Overcoming resistance to interferon- induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation. J Clin Oncol 2006; 24:3771-9.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3771-3779
-
-
Reu, F.J.1
Bae, S.I.2
Cherkassky, L.3
Leaman, D.W.4
Lindner, D.5
Beaulieu, N.6
|