Mitigating effects of antioxidant properties of Artemisia campestris leaf extract on hyperlipidemia, advanced glycation end products and oxidative stress in alloxan-induced diabetic rats

Food and Chemical Toxicology

Volumn 48, Issue 7, 2010, Pages 1986-1993

  Sefi, Mediha ^a   Fetoui, Hamadi ^a   Makni, Mohamed ^a   Zeghal, Najiba ^a  

^a Animal Physiology Laboratory   (Tunisia)

Author keywords

Artemisia campestris; Biochemical parameters; Diabetes; Oxidative stress; Pancreas; Rat

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ARTEMISIA CAMPESTRIS EXTRACT; CARBONYL DERIVATIVE; CATALASE; CHOLESTEROL; FLAVONOID; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLANT EXTRACT; PROTEIN; QUERCETIN; SUPEROXIDE DISMUTASE; TANNIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTEMISIA; ARTEMISIA CAMPESTRIS; ARTICLE; CHOLESTEROL BLOOD LEVEL; COMPLICATION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; DRUG MEGADOSE; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPERLIPIDEMIA; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTIOXIDANTS; ARTEMISIA; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, EXPERIMENTAL; FLAVONOIDS; GLUCOSE TOLERANCE TEST; GLYCOSYLATION END PRODUCTS, ADVANCED; HYPERLIPIDEMIAS; HYPOLIPIDEMIC AGENTS; INSULIN; LIPIDS; MALE; OXIDATIVE STRESS; PANCREAS; PHENOLS; PLANT EXTRACTS; PLANT LEAVES; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; TANNINS; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

ARTEMISIA CAMPESTRIS; RATTUS;

EID: 77953536407     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.05.005     Document Type: Article

References (68)

1. Aebi H. Catalase in vitro. Methods. Enzymol. 1984, 105:121-126.
2. Ananthan R., Latha M., Pari L., Baskar C., Narmatha V. Modulatory effects of Gymnema montanum leaf extract on alloxan induced oxidative stress in wistar rats. Nutrition 2004, 20:280-285.
3. Baynes J.W. The role of oxidative stress in the development of complication in diabetes. Diabetes 1991, 40:405-412.
4. Beauchamp C., Fridovich I. Superoxide dismutase: improved assays and an assay applicable to acrylamide gel. Anal. Biochem. 1971, 44:276-287.
5. Behmanesh B., Heshmati G.A., Mazandarani M., Rezaei M.B., Ahmadi A.R., Ghaemi E.O., Bakhshandeh Nosrat S. Chemical composition and antibacterial activity from essential oil of Artemisia sieberi Besser subsp. Sieberi in North of Iran. Asian J. Plant. Sci. 2007, 6:562-564.
6. Bopanna K.N., Kannan J., Sushma G., Balaraman R., Rathod S.P. Antidiabetic and antihyperlipidemic effects of neem kernel powder on alloxan diabetic rabbits. Ind. J. Pharmacol. 1997, 29:162-167.
7. Boukef, M.K., 1986. In: Librairie Larose, (Ed.), Les plantes dans la médecine traditionnelle tunisienne. Médecine traditionnelle et pharmacopée, Paris, pp. 350.
8. Brown J.E., Khodr H., Hider R.C., Rice-Evans C.A. Structure dependence of flavonoid interactions with Cu2+ ions: implications for their antioxidant properties. J. Biochem. 1998, 330:1173-1178.
9. Chanwitheesuk A., Teerawutgulrag A., Rakariyatham N. Screening of antioxidant activity and antioxidant compounds of some edible plants of Thailand. Food Chem. 2005, 92:491-497.
10. Cuenod A., Pottier-Alapetite G., Labre A. Flore Analytique et Synoptique de la Tunisie: Cryptogames Vasculaires Gymnospermes et monocotyledones 1954, Office de l'experimentation et de la vulgarisation agricoles de Tunisie, Tunis, pp. 39-287.
11. Das N.P., Ramanathan L. Studies on flavonoids and related compounds as anti-oxidants in food. Lipid-Soluble Anti-Oxidants: Biochemistry and Clinical Applications 1992, 295-306. Birkhauser, Basel. A.S.H. Ong, L. Packer (Eds.).
12. Dincer Y., Akcay T., Alademir Z., Ilkova H. Effects of oxidative stress on glutathione pathway in red blood cells from patients with insulin-dependant diabetes mellitus. Metabolism 2002, 51:1360-1362.
13. Draper H.H., Hadley M. Malondialdehyde determination as index of lipid peroxidation. Meth. Enzymol. 1990, 86:421-431.
14. Dukworth W.C. Hyperglycemia and cardiovascular disease. Curr. Atheroscler. Rep. 2001, 3:383-391.
15. Dunn D., Sheehan H., McLetchin N. Necrosis of islets of langerhans produced experimentally. Lancet 1943, 244:484-487.
16. Ellman G.L. Tissue sulfhydryl groups. Arch. Biochem. 1959, 82:70-77.
17. Feillet-Coudray C., Rock E., Coudray C., Grzelkowska K., Azais-Braesco V., Dardevet D. Lipid peroxidation and antioxidant status in experimental diabetes. Clin. Chim. Acta 1999, 284:31-43.
18. Flohe L., Gunzler W.A. Assays of glutathione peroxidase. Meth. Enzymol. 1984, 105:114-121.
19. Friedewald W.T., Levy R.T., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin. Chem. 1972, 226:499-502.
20. Furusho T., Kataota E., Yasuhara T., Wada M., Innami S. Administration of ß-carotene suppresses lipidperoxidation in tissues and improves the glucose tolerance ability of streptozotocin-induced diabetic rats. Int. J. Vitam. Nutr. Res. 2002, 72:71-76.
21. Gallan P.M., Carrascosa A., Gussinye M., Dominguez C. Biomarkers of diabetes-associated oxidative stress and antioxidant status in young diabetic patients with or without subclinical complication. Free Radic. Biol. Med. 2003, 34:1563-1574.
22. Goldberg R.B. Lipid disorders in diabetes. Diab. Care 1981, 4:561-572.
23. Hanasaki Y., Ogawa S., Fukui S. The correlation between active oxygens scavenging and antioxidative effects of flavonoids. Free Radical. Biol. Med. 1994, 16:845-850.
24. Heikkila R.E., Winston B., Cohen G., Barden H. Alloxan induced diabetes, evidence for hydroxyl radicals as a cytotoxic intermediate. Biochem. Pharmacol. 1976, 25:1085-1092.
25. Hong J.H., Lee I.S. Effects of Artemisia capillaris ethyl acetate fraction on oxidative stress and antioxidant enzyme in high-fat diet induced obese mice. Chem. Biol. Interact. 2009, 179:88-93.
26. Hurabielle M., Eberle J., Paris M. Flavonoids of Artemisia campestris ssp. glutinosa. Planta. Med. 1982, 46:124-125.
27. Jean, V., Jiri, S., 1983. Plantes médicinales. In: Larousse (Ed.), 250 Illustrations en Couleurs, Paris, pp. 319.
28. Jollow D.J., Mitchell J.R., Zamppaglione Z., Gillette J.R. Bromobenzene induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolites. Pharmacology 1974, 11:151-157.
29. Jovanovic S.V., Steenken S., Tosic M., Marjanovic B., Simic M.G. Flavonoids as antioxidants. J. Am. Chem. Soc. 1994, 116:4846-4851.
30. Julkunen-Titto R. Phenolic constituents in the leaves of northern willows: methods for the analysis of certain phenolics. J. Agric. Food Chem. 1985, 33:213-217.
31. Kayali R., Cakatay U., Akcay T., Altug T. Effect of alpha-lipoic acid supplementation on markers of protein oxidation in post-mitotic tissues of ageing rat. Cell Biochem. Funct. 2006, 24:79-85.
32. 2+ in alloxan-induced pancreatic beta-cell damage. Biochem. Biophys. Acta 1994, 1227:87-91.
33. Larson R.A. The antioxidants of higher plants. Phytochemistry 1988, 27:969-978.
34. Locckie L.Z., Meerman J.H.N., Commander J.N.M., Vermeulen N.P.E. Biomarkers of free radical damage: application in experimental animals and in human. Free Radic. Biol. Med. 1999, 26:202-226.
35. Lowry O.H., Rosenbrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951, 193:265-275.
36. Mansour H.A., Newairy A.A., Youssef M.I., Sheweita S.A. Biochemical study on the effects of some Egyptian herbs in alloxan-induced diabetic rats. Toxicology 2002, 170:221-228.
37. Markku L. Epidemiology of diabetes dyslipidemia. Diab. Rev. 1995, 3:408-422.
38. Memmi A., Sansa G., Rjeibi I., El Ayeb M., Srairi-Abid N., Bellasfer Z., Fekhih A. Use of medicinal plants against scorpionic and ophidian venoms. Arch. Inst. Pasteur. Tunis. 2007, 84:49-55.
39. Middleton E. Biological properties of plant flavonoids: an overview. Int. J. Pharmacol. 1996, 34:344-348.
40. 50 and its error by means of logarithmic Probit paper. Proc. Soc. Exp. Biol. Med. 1944, 57:261-264.
41. Miura T., Itoh C., Iwamoto N., Kato M., Kawai M., Park S.R., Suzuki I. Hypoglycemic activity of the fruit of the Momordica charantia in type 2 diabetic mice. J. Nutr. Sci. Vitaminol. 2001, 47:340-344.
42. Murota K., Terao J. Antioxidative flavonoid quercetin: implication of its intestinal absorption and mechanism. Arch. Biochem. Biophys. 2003, 12:1193-1196.
43. Nazirogilu M., Butterworth P. Protective effects of moderate exercise with dietary vitamin C and E on blood antioxidative defense mechanism in rats with streptozotocin-induced diabetes. App. Physiol. Nutr. Metab. 2005, 30:172-185.
44. Nicotera P., Orrenius S. Role of thiols in protection against biological reactive intermediates. Adv. Exp. Med. Biol. 1986, 197:41-49.
45. Obrosova I., Fathallah L., Liu E., Nourooz-Zadeh J. Early oxidative stress in diabetic kidney: effect of DL-alpha lipoic acid. Free Radical. Bio. Med. 2003, 34:186-195.
46. Okutan P.A., Ozcelik N., Yilmaz H.R., Uz E. Effects of caffeic acid phenethyl ester on lipid peroxidation and antioxidant enzymes in diabetic rat heart. Clin. Biochem. 2005, 38:191-196.
47. Osawa T., Kato Y. Protective role of antioxidative food factors in oxidative stress caused by hyperglycemia. Ann. NY Acad. Sci. 2005, 1043:440-451.
48. Ozkaya Y.G., Agar A., Yargicoglu P., Hacioglu G., Bilmen Sarikcioglu S. The effect of exercise on brain antioxidant status of diabetic rats. Diab. Metabol. 2002, 28:377-384.
49. Paganga G., Al-Hashim H., Khodr H., Scott B.C., Aruoma O.I., Hider R.C., Halliwell B., Rice-Evans C.A. Mechanisms of antioxidant activities of quercetin and catechin. Redox Rep. 1996, 2:359-364.
50. Park B.H., Rho H.W., Park J.W., Cho C.G., Kim J.S., Chung H.T., Kim H.R. Protective mechanism of glucose against alloxan-induced pancreatic beta-cell damage. Biochem. Biophys. Res. Commun. 1995, 210:1-6.
51. Rajasekaran S., Kasiappan R., Karuran S., Sorimutha S. Beneficial effects of Aloe Vera Leaf Gel extract on lipid profile status in rats with streptozotocin diabetes. Clin. Exp. Pharmacol. P 2006, 33:232-237.
52. Reznick A.Z., Packer L. Oxidative Damage to Proteins: Spectrophotometric Method for Carbonyl. Method Enzymol 1994, Academic Press, New York, pp. 357.
53. Reznick A.Z., Packer L. Oxidative damage to proteins: spectrophotometric method for carbonyl. Method Enzymol 1994, Academic. Press, New York, pp. 357.
54. Ribes G., Dacosta C., Loubatieres-Mariani M.M. Hypocholesterolaemic and hypotriglyceridaemic effects of subfractions from fenugreek seeds in diabetic dogs. Physiol. Res. 1987, 1:38-43.
55. Sharma S.B., Nasir A., Prabhu K.M., Murthy P.S., Gev G. Hypoglycaemic and hypolipidemic effect of ethanolic extract of seeds of Eugenia jambolana in alloxan-induced diabetic rabbits. J. Ethnopharmacol. 2003, 85:201-206.
56. Sheweita S.A., Newairy A.A., Mansour H.A., Youssef M.I. Effect of some hypoglycaemic herbs on the activity of phase I and II drug-metabolizing enzymes in alloxan-induced diabetic rats. Toxicology 2002, 174:131-139.
57. Solomon G., Raosaheb K.K., Nazma B. Alteration in antioxidant enzymes and oxidative damage in experimental diabetic rat tissues: effect of Vanadate and fenugreek (Trigonella foenum graecum). Mol. Cell Biochem. 2002, 236:7-12.
58. Sozmen E.Y., Sozmen B., Delen Y., Onat T. Catalase/superoxide dismutase (SOD) and catalase/paraoxonase (PON) ratios implicate poor glycemic control. Arch. Med. Res. 2001, 32:283-287.
59. Sugiura M., Ohshima M., Ogawa K., Yano M. Chronic administration of Satsuma mandarin fruit (Citrus unshiu Marc.) improves oxidative stress in streptozotocin-induced diabetic rat liver. Biol. Pharm. Bull 2006, 29:588-591.
60. Szkudelski T. The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol. Res. 2001, 50:536-546.
61. Vasu V.T., Modi H., Thaikoottathil J.V., Gupta S. Hypolipidaemic and antioxidant effect of Enicostemma littorale Blume aqueous extract in cholesterol fed rats. J. Ethnopharmacol. 2005, 101:277-282.
62. Venkateshwarlu V., Kokate C.K., Rambhau D., Veerasham C. Antidiabetic activity of roots of Salacia macrosperma. Planta. Med. 1993, 59:391.
63. Venkateswaran S., Pari L. Antioxidant effect of Phaseolus vulgaris in streptozotocin-induced diabetic rats. Asia Pac. J. Clin. Nutr. 2002, 11:206-209.
64. Verma A.K., Johnson J.A., Gould M.N., Tanner M.A. Inhibition of 7,12-dimethylbenz(a)anthracene and N-nitro-methylurea induced rat mammary cancer by dietary flavonolquercetin. Cancer Res. 1998, 48:5754-5788.
65. Wollenweber, E., 1988. Occurrence of flavonoid aglycones in medicinal plants. In: Cody, V, Middelton Jr., E., Harbone, J.B., Beretz A. (Eds.), Plant Flavonoids in Biology and Medicine II: Biochemical, Cellular and Medicinal Properties. Prog. Clin. Biol. Res. pp. 45-55.
66. Yilmaz H.R., Uz E., Yucel N., Altuntas I., Ozcelic N. Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver. J. Biochem. Mol. Toxic. 2004, 18:234-238.
67. Yoshida M., Sakai T., Hosokawa N., Marui N., Matsumoto K., Fujioka A. The effect of quercetin on cell cycle progression and growth of human gastric cancer cells. FEBS Lett. 1990, 260:10-13.
68. Zhishen J., Mengcheng T., Jianming W. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem. 1999, 64:555-559.