IL-10 administration reduces PGE-2 levels and promotes CR3-mediated clearance of Escherichia coli K1 by phagocytes in meningitis

Journal of Experimental Medicine

Volumn 207, Issue 6, 2010, Pages 1307-1319

  Mittal, Rahul ^a   Gonzalez Gomez, Ignacio ^a,b   Panigrahy, Ashok ^a,b   Goth, Kerstin ^a   Bonnet, Richard ^c   Prasadarao, Nemani V ^a,b  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CEFOTAXIME; CELL SURFACE RECEPTOR; CHEMOKINE RECEPTOR CXCR3; FC RECEPTOR; INTERLEUKIN 10; PROSTAGLANDIN E2; PROTEIN CR3; RECOMBINANT INTERLEUKIN 10; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; APOPTOSIS; ARTICLE; BACTEREMIA; BACTERIAL MENINGITIS; BACTERICIDAL ACTIVITY; BRAIN DAMAGE; BRAIN PROTECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DOSE RESPONSE; DRUG TREATMENT FAILURE; ESCHERICHIA COLI; HISTOPATHOLOGY; HUMAN; MACROPHAGE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NEUTROPHIL CHEMOTAXIS; NEWBORN; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; PHAGOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE DRUG DOSE; WILD TYPE;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES; BACTEREMIA; BRAIN; DINOPROSTONE; ESCHERICHIA COLI; HUMANS; INFLAMMATION; INTERLEUKIN-10; MACROPHAGE-1 ANTIGEN; MACROPHAGES; MENINGITIS, ESCHERICHIA COLI; MICE; NEUTROPHILS; PHAGOCYTES; PHAGOCYTOSIS; SURVIVAL ANALYSIS; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 77953531311     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20092265     Document Type: Article

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