메뉴 건너뛰기




Volumn 40, Issue 7, 2010, Pages 623-635

AGEs/RAGE in CKD: Irreversible metabolic memory road toward CVD?

Author keywords

Advanced glycation end products (AGEs); Chronic kidney disease (CKD); Endogenous secretory RAGE (esRAGE); Oxidative stress; Receptor for AGEs (RAGE); Soluble RAGE (sRAGE)

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; AUTACOID; BIOLOGICAL MARKER;

EID: 77953522847     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2010.02298.x     Document Type: Review
Times cited : (45)

References (137)
  • 1
    • 0016403709 scopus 로고
    • Accelerated atherosclerosis in prolonged maintenance hemodialysis
    • Lindner A, Charra B, Sherrard DJ, Scribner BH. Accelerated atherosclerosis in prolonged maintenance hemodialysis. N Engl J Med 1974 290: 697 701.
    • (1974) N Engl J Med , vol.290 , pp. 697-701
    • Lindner, A.1    Charra, B.2    Sherrard, D.J.3    Scribner, B.H.4
  • 2
    • 0032229826 scopus 로고    scopus 로고
    • Epidemiology of cardiovascular disease in chronic renal disease
    • Foley RN, Parfrey PS, Sarnak MJ. Epidemiology of cardiovascular disease in chronic renal disease. J Am Soc Nephrol 1998 9: S16 23.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 16-23
    • Foley, R.N.1    Parfrey, P.S.2    Sarnak, M.J.3
  • 3
    • 0034922894 scopus 로고    scopus 로고
    • Prevalence and clinical correlates of coronary artery disease among new dialysis patients in the United States: A cross-sectional study
    • Stack AG, Bloembergen WE. Prevalence and clinical correlates of coronary artery disease among new dialysis patients in the United States: a cross-sectional study. J Am Soc Nephrol 2001 12: 1516 1523.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 1516-1523
    • Stack, A.G.1    Bloembergen, W.E.2
  • 4
    • 2342519703 scopus 로고    scopus 로고
    • The United States Renal Data System
    • USRDS.
    • USRDS. The United States Renal Data System. Am J Kidney Dis 2003 42: 1 230.
    • (2003) Am J Kidney Dis , vol.42 , pp. 1-230
  • 5
    • 3242811281 scopus 로고    scopus 로고
    • Myocardial scintigraphy using a fatty acid analogue detects coronary artery disease in hemodialysis patients
    • Nishimura M, Hashimoto T, Kobayashi H, Fukuda T, Okino K, Yamamoto N et al. Myocardial scintigraphy using a fatty acid analogue detects coronary artery disease in hemodialysis patients. Kidney Int 2004 66: 811 819.
    • (2004) Kidney Int , vol.66 , pp. 811-819
    • Nishimura, M.1    Hashimoto, T.2    Kobayashi, H.3    Fukuda, T.4    Okino, K.5    Yamamoto, N.6
  • 6
    • 0030995276 scopus 로고    scopus 로고
    • Onset of coronary artery disease prior to initiation of haemodialysis in patients with end-stage renal disease
    • Joki N, Hase H, Nakamura R, Yamaguchi T. Onset of coronary artery disease prior to initiation of haemodialysis in patients with end-stage renal disease. Nephrol Dial Transplant 1997 12: 718 723.
    • (1997) Nephrol Dial Transplant , vol.12 , pp. 718-723
    • Joki, N.1    Hase, H.2    Nakamura, R.3    Yamaguchi, T.4
  • 7
    • 24344477577 scopus 로고    scopus 로고
    • High prevalence of occult coronary artery stenosis in patients with chronic kidney disease at the initiation of renal replacement therapy: An angiographic examination
    • Ohtake T, Kobayashi S, Moriya H, Negishi K, Okamoto K, Maesato K et al. High prevalence of occult coronary artery stenosis in patients with chronic kidney disease at the initiation of renal replacement therapy: an angiographic examination. J Am Soc Nephrol 2005 16: 1141 1148.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1141-1148
    • Ohtake, T.1    Kobayashi, S.2    Moriya, H.3    Negishi, K.4    Okamoto, K.5    Maesato, K.6
  • 8
    • 33748430950 scopus 로고    scopus 로고
    • Risk factors for de novo acute cardiac events in patients initiating hemodialysis with no previous cardiac symptom
    • Hase H, Tsunoda T, Tanaka Y, Takahashi Y, Imamura Y, Ishikawa H et al. Risk factors for de novo acute cardiac events in patients initiating hemodialysis with no previous cardiac symptom. Kidney Int 2006 70: 1142 1148.
    • (2006) Kidney Int , vol.70 , pp. 1142-1148
    • Hase, H.1    Tsunoda, T.2    Tanaka, Y.3    Takahashi, Y.4    Imamura, Y.5    Ishikawa, H.6
  • 12
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group
    • UKPDS.
    • UKPDS. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998 352: 837 853.
    • (1998) Lancet , vol.352 , pp. 837-853
  • 15
    • 4544249175 scopus 로고    scopus 로고
    • Chronic kidney disease predicts cardiovascular disease
    • Hostetter TH. Chronic kidney disease predicts cardiovascular disease. N Engl J Med 2004 351: 1344 1346.
    • (2004) N Engl J Med , vol.351 , pp. 1344-1346
    • Hostetter, T.H.1
  • 16
    • 0019475899 scopus 로고
    • Nonenzymatic browning in vivo: Possible process for aging of long-lived proteins
    • Monnier VM, Cerami A. Nonenzymatic browning in vivo: possible process for aging of long-lived proteins. Science 1981 211: 491 493.
    • (1981) Science , vol.211 , pp. 491-493
    • Monnier, V.M.1    Cerami, A.2
  • 17
    • 0031040243 scopus 로고    scopus 로고
    • Oxidation conspires with glycation to generate noxious advanced glycation end products in renal failure
    • Miyata T, Maeda K, Kurokawa K, van Ypersele de Strihou C. Oxidation conspires with glycation to generate noxious advanced glycation end products in renal failure. Nephrol Dial Transplant 1997 12: 255 258.
    • (1997) Nephrol Dial Transplant , vol.12 , pp. 255-258
    • Miyata, T.1    Maeda, K.2    Kurokawa, K.3    Van Ypersele De Strihou, C.4
  • 18
    • 0028073640 scopus 로고
    • Erythrocyte redox state in uremic anemia: Effects of hemodialysis and relevance of glutathione metabolism
    • Canestrari F, Galli F, Giorgini A, Albertini MC, Galiotta P, Pascucci M et al. Erythrocyte redox state in uremic anemia: effects of hemodialysis and relevance of glutathione metabolism. Acta Haematol 1994 91: 187 193.
    • (1994) Acta Haematol , vol.91 , pp. 187-193
    • Canestrari, F.1    Galli, F.2    Giorgini, A.3    Albertini, M.C.4    Galiotta, P.5    Pascucci, M.6
  • 19
    • 0030902220 scopus 로고    scopus 로고
    • Implication of an increased oxidative stress in the formation of advanced glycation end products in patients with end-stage renal failure
    • Miyata T, Wada Y, Cai Z, Iida Y, Horie K, Yasuda Y et al. Implication of an increased oxidative stress in the formation of advanced glycation end products in patients with end-stage renal failure. Kidney Int 1997 51: 1170 1181.
    • (1997) Kidney Int , vol.51 , pp. 1170-1181
    • Miyata, T.1    Wada, Y.2    Cai, Z.3    Iida, Y.4    Horie, K.5    Yasuda, Y.6
  • 20
    • 5444257487 scopus 로고    scopus 로고
    • Oxidative stress in uremia: Nature, mechanisms, and potential consequences
    • Vaziri ND. Oxidative stress in uremia: nature, mechanisms, and potential consequences. Semin Nephrol 2004 24: 469 473.
    • (2004) Semin Nephrol , vol.24 , pp. 469-473
    • Vaziri, N.D.1
  • 21
    • 0031656155 scopus 로고    scopus 로고
    • Autoxidation products of both carbohydrates and lipids are increased in uremic plasma: Is there oxidative stress in uremia?
    • Miyata T, Fu MX, Kurokawa K, van Ypersele de Strihou C, Thorpe SR, Baynes JW. Autoxidation products of both carbohydrates and lipids are increased in uremic plasma: is there oxidative stress in uremia? Kidney Int 1998 54: 1290 1295.
    • (1998) Kidney Int , vol.54 , pp. 1290-1295
    • Miyata, T.1    Fu, M.X.2    Kurokawa, K.3    Van Ypersele De Strihou, C.4    Thorpe, S.R.5    Baynes, J.W.6
  • 23
    • 0038015008 scopus 로고    scopus 로고
    • Dialysis filter type determines the acute effect of haemodialysis on endothelial function and oxidative stress
    • Kosch M, Levers A, Fobker M, Barenbrock M, Schaefer RM, Rahn KH et al. Dialysis filter type determines the acute effect of haemodialysis on endothelial function and oxidative stress. Nephrol Dial Transplant 2003 18: 1370 1375.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 1370-1375
    • Kosch, M.1    Levers, A.2    Fobker, M.3    Barenbrock, M.4    Schaefer, R.M.5    Rahn, K.H.6
  • 25
    • 18844471606 scopus 로고    scopus 로고
    • Advanced oxidation protein products as novel mediators of inflammation and monocyte activation in chronic renal failure
    • Witko-Sarsat V, Friedlander M, Nguyen Khoa T, Capeillere-Blandin C, Nguyen AT, Canteloup S et al. Advanced oxidation protein products as novel mediators of inflammation and monocyte activation in chronic renal failure. J Immunol 1998 161: 2524 2532.
    • (1998) J Immunol , vol.161 , pp. 2524-2532
    • Witko-Sarsat, V.1    Friedlander, M.2    Nguyen Khoa, T.3    Capeillere-Blandin, C.4    Nguyen, A.T.5    Canteloup, S.6
  • 26
    • 33748306000 scopus 로고    scopus 로고
    • Increased phagocytic nicotinamide adenine dinucleotide phosphate oxidase-dependent superoxide production in patients with early chronic kidney disease
    • Fortuno A, Beloqui O, San Jose G, Moreno MU, Zalba G, Diez J. Increased phagocytic nicotinamide adenine dinucleotide phosphate oxidase-dependent superoxide production in patients with early chronic kidney disease. Kidney Int Suppl 2005 68: S71 5.
    • (2005) Kidney Int Suppl , vol.68 , pp. 71-5
    • Fortuno, A.1    Beloqui, O.2    San Jose, G.3    Moreno, M.U.4    Zalba, G.5    Diez, J.6
  • 27
    • 29244461434 scopus 로고    scopus 로고
    • The determinants of endothelial dysfunction in CKD: Oxidative stress and asymmetric dimethylarginine
    • Yilmaz MI, Saglam M, Caglar K, Cakir E, Sonmez A, Ozgurtas T et al. The determinants of endothelial dysfunction in CKD: oxidative stress and asymmetric dimethylarginine. Am J Kidney Dis 2006 47: 42 50.
    • (2006) Am J Kidney Dis , vol.47 , pp. 42-50
    • Yilmaz, M.I.1    Saglam, M.2    Caglar, K.3    Cakir, E.4    Sonmez, A.5    Ozgurtas, T.6
  • 29
    • 79952985620 scopus 로고    scopus 로고
    • Cardiovascular complications in renal failure: Implications of advanced glycation end-products and their receptor, RAGE
    • Miyata, T. Eckardt, K.U. Nangaku, M. editors.
    • Koyama H, Nishizawa Y. Cardiovascular complications in renal failure: implications of advanced glycation end-products and their receptor, RAGE. In: Miyata T, Eckardt KU, Nangaku M, editors. Oxidative Stress in Applied Basic Research and Clinical Practice 'Renal Disorders'.
    • Oxidative Stress in Applied Basic Research and Clinical Practice 'Renal Disorders'.
    • Koyama, H.1    Nishizawa, Y.2
  • 31
    • 33645955293 scopus 로고    scopus 로고
    • Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients
    • Meerwaldt R, Hartog JW, Graaff R, Huisman RJ, Links TP, den Hollander NC et al. Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients. J Am Soc Nephrol 2005 16: 3687 3693.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3687-3693
    • Meerwaldt, R.1    Hartog, J.W.2    Graaff, R.3    Huisman, R.J.4    Links, T.P.5    Den Hollander, N.C.6
  • 32
    • 51649086086 scopus 로고    scopus 로고
    • Skin autofluorescence, a marker for advanced glycation end product accumulation, is associated with arterial stiffness in patients with end-stage renal disease
    • Ueno H, Koyama H, Tanaka S, Fukumoto S, Shinohara K, Shoji T et al. Skin autofluorescence, a marker for advanced glycation end product accumulation, is associated with arterial stiffness in patients with end-stage renal disease. Metabolism 2008 57: 1452 1457.
    • (2008) Metabolism , vol.57 , pp. 1452-1457
    • Ueno, H.1    Koyama, H.2    Tanaka, S.3    Fukumoto, S.4    Shinohara, K.5    Shoji, T.6
  • 36
    • 0034827942 scopus 로고    scopus 로고
    • Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease
    • Shoji T, Emoto M, Shinohara K, Kakiya R, Tsujimoto Y, Kishimoto H et al. Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease. J Am Soc Nephrol 2001 12: 2117 2124.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 2117-2124
    • Shoji, T.1    Emoto, M.2    Shinohara, K.3    Kakiya, R.4    Tsujimoto, Y.5    Kishimoto, H.6
  • 37
    • 25644446207 scopus 로고    scopus 로고
    • Impact of brachial-ankle pulse wave velocity and ankle-brachial blood pressure index on mortality in hemodialysis patients
    • Kitahara T, Ono K, Tsuchida A, Kawai H, Shinohara M, Ishii Y et al. Impact of brachial-ankle pulse wave velocity and ankle-brachial blood pressure index on mortality in hemodialysis patients. Am J Kidney Dis 2005 46: 688 696.
    • (2005) Am J Kidney Dis , vol.46 , pp. 688-696
    • Kitahara, T.1    Ono, K.2    Tsuchida, A.3    Kawai, H.4    Shinohara, M.5    Ishii, Y.6
  • 38
    • 0032889858 scopus 로고    scopus 로고
    • Increased advanced glycation end products in atherosclerotic lesions of patients with end-stage renal disease
    • Sakata N, Imanaga Y, Meng J, Tachikawa Y, Takebayashi S, Nagai R et al. Increased advanced glycation end products in atherosclerotic lesions of patients with end-stage renal disease. Atherosclerosis 1999 142: 67 77.
    • (1999) Atherosclerosis , vol.142 , pp. 67-77
    • Sakata, N.1    Imanaga, Y.2    Meng, J.3    Tachikawa, Y.4    Takebayashi, S.5    Nagai, R.6
  • 39
    • 0027956982 scopus 로고
    • Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency
    • Bucala R, Makita Z, Vega G, Grundy S, Koschinsky T, Cerami A et al. Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency. Proc Natl Acad Sci USA 1994 91: 9441 9445.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9441-9445
    • Bucala, R.1    Makita, Z.2    Vega, G.3    Grundy, S.4    Koschinsky, T.5    Cerami, A.6
  • 41
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis
    • Stocker R, Keaney JF Jr. Role of oxidative modifications in atherosclerosis. Physiol Rev 2004 84: 1381 1478.
    • (2004) Physiol Rev , vol.84 , pp. 1381-1478
    • Stocker, R.1    Keaney, Jr.J.F.2
  • 42
    • 33845398312 scopus 로고    scopus 로고
    • Plasma pentosidine and total homocysteine levels in relation to change in common carotid intima-media area in the first year of dialysis therapy
    • Suliman ME, Stenvinkel P, Jogestrand T, Maruyama Y, Qureshi AR, Barany P et al. Plasma pentosidine and total homocysteine levels in relation to change in common carotid intima-media area in the first year of dialysis therapy. Clin Nephrol 2006 66: 418 425.
    • (2006) Clin Nephrol , vol.66 , pp. 418-425
    • Suliman, M.E.1    Stenvinkel, P.2    Jogestrand, T.3    Maruyama, Y.4    Qureshi, A.R.5    Barany, P.6
  • 43
    • 77953500963 scopus 로고    scopus 로고
    • Advanced glycation end-products, carotid atherosclerosis and circulating endothelial progenitor cells in patients with end-stage renal disease
    • in press).
    • Ueno H, Koyama H, Fukumoto S, Tanaka S, Shoji T, Shoji T et al. Advanced glycation end-products, carotid atherosclerosis and circulating endothelial progenitor cells in patients with end-stage renal disease. Metabolism 2010 in press).
    • (2010) Metabolism
    • Ueno, H.1    Koyama, H.2    Fukumoto, S.3    Tanaka, S.4    Shoji, T.5    Shoji, T.6
  • 44
    • 33745683623 scopus 로고    scopus 로고
    • Oxidative stress, advanced glycation end product, and coronary artery calcification in hemodialysis patients
    • Taki K, Takayama F, Tsuruta Y, Niwa T. Oxidative stress, advanced glycation end product, and coronary artery calcification in hemodialysis patients. Kidney Int 2006 70: 218 224.
    • (2006) Kidney Int , vol.70 , pp. 218-224
    • Taki, K.1    Takayama, F.2    Tsuruta, Y.3    Niwa, T.4
  • 46
    • 33746009579 scopus 로고    scopus 로고
    • Low molecular weight advanced glycation end products predict mortality in asymptomatic patients receiving chronic haemodialysis
    • Roberts MA, Thomas MC, Fernando D, Macmillan N, Power DA, Ierino FL. Low molecular weight advanced glycation end products predict mortality in asymptomatic patients receiving chronic haemodialysis. Nephrol Dial Transplant 2006 21: 1611 1617.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 1611-1617
    • Roberts, M.A.1    Thomas, M.C.2    Fernando, D.3    MacMillan, N.4    Power, D.A.5    Ierino, F.L.6
  • 48
    • 0036315606 scopus 로고    scopus 로고
    • Advanced glycation end products and mortality in hemodialysis patients
    • Schwedler SB, Metzger T, Schinzel R, Wanner C. Advanced glycation end products and mortality in hemodialysis patients. Kidney Int 2002 62: 301 310.
    • (2002) Kidney Int , vol.62 , pp. 301-310
    • Schwedler, S.B.1    Metzger, T.2    Schinzel, R.3    Wanner, C.4
  • 49
    • 3042762893 scopus 로고    scopus 로고
    • Potential cardiovascular risk factors in chronic kidney disease: AGEs, total homocysteine and metabolites, and the C-reactive protein
    • Busch M, Franke S, Muller A, Wolf M, Gerth J, Ott U et al. Potential cardiovascular risk factors in chronic kidney disease: AGEs, total homocysteine and metabolites, and the C-reactive protein. Kidney Int 2004 66: 338 347.
    • (2004) Kidney Int , vol.66 , pp. 338-347
    • Busch, M.1    Franke, S.2    Muller, A.3    Wolf, M.4    Gerth, J.5    Ott, U.6
  • 50
    • 0036413438 scopus 로고    scopus 로고
    • The malnutrition, inflammation, and atherosclerosis (MIA) syndrome-The heart of the matter
    • Pecoits-Filho R, Lindholm B, Stenvinkel P. The malnutrition, inflammation, and atherosclerosis (MIA) syndrome-the heart of the matter. Nephrol Dial Transplant 2002 17 (Suppl. 11 28 31.
    • (2002) Nephrol Dial Transplant , vol.17 , Issue.SUPPL. 11 , pp. 28-31
    • Pecoits-Filho, R.1    Lindholm, B.2    Stenvinkel, P.3
  • 51
    • 58249118039 scopus 로고    scopus 로고
    • Association of Malnutrition-Inflammation Score with quality of life and mortality in hemodialysis patients: A 5-year prospective cohort study
    • Rambod M, Bross R, Zitterkoph J, Benner D, Pithia J, Colman S et al. Association of Malnutrition-Inflammation Score with quality of life and mortality in hemodialysis patients: a 5-year prospective cohort study. Am J Kidney Dis 2009 53: 298 309.
    • (2009) Am J Kidney Dis , vol.53 , pp. 298-309
    • Rambod, M.1    Bross, R.2    Zitterkoph, J.3    Benner, D.4    Pithia, J.5    Colman, S.6
  • 52
    • 0026650438 scopus 로고
    • Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface
    • Schmidt AM, Vianna M, Gerlach M, Brett J, Ryan J, Kao J et al. Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface. J Biol Chem 1992 267: 14987 14997.
    • (1992) J Biol Chem , vol.267 , pp. 14987-14997
    • Schmidt, A.M.1    Vianna, M.2    Gerlach, M.3    Brett, J.4    Ryan, J.5    Kao, J.6
  • 53
    • 0026659883 scopus 로고
    • Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins
    • Neeper M, Schmidt AM, Brett J, Yan SD, Wang F, Pan YC et al. Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. J Biol Chem 1992 267: 14998 14004.
    • (1992) J Biol Chem , vol.267 , pp. 14998-14004
    • Neeper, M.1    Schmidt, A.M.2    Brett, J.3    Yan, S.D.4    Wang, F.5    Pan, Y.C.6
  • 54
    • 55249118389 scopus 로고    scopus 로고
    • Structural basis for pattern recognition by the receptor for advanced glycation end products (RAGE)
    • Xie J, Reverdatto S, Frolov A, Hoffmann R, Burz DS, Shekhtman A. Structural basis for pattern recognition by the receptor for advanced glycation end products (RAGE). J Biol Chem 2008 283: 27255 27269.
    • (2008) J Biol Chem , vol.283 , pp. 27255-27269
    • Xie, J.1    Reverdatto, S.2    Frolov, A.3    Hoffmann, R.4    Burz, D.S.5    Shekhtman, A.6
  • 55
    • 56749146313 scopus 로고    scopus 로고
    • Solution structure of the variable-type domain of the receptor for advanced glycation end products: New insight into AGE-RAGE interaction
    • Matsumoto S, Yoshida T, Murata H, Harada S, Fujita N, Nakamura S et al. Solution structure of the variable-type domain of the receptor for advanced glycation end products: new insight into AGE-RAGE interaction. Biochemistry 2008 47: 12299 12311.
    • (2008) Biochemistry , vol.47 , pp. 12299-12311
    • Matsumoto, S.1    Yoshida, T.2    Murata, H.3    Harada, S.4    Fujita, N.5    Nakamura, S.6
  • 56
    • 0033603241 scopus 로고    scopus 로고
    • RAGE mediates a novel proinflammatory axis: A central cell surface receptor for S100/calgranulin polypeptides
    • Hofmann MA, Drury S, Fu C, Qu W, Taguchi A, Lu Y et al. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 1999 97: 889 901.
    • (1999) Cell , vol.97 , pp. 889-901
    • Hofmann, M.A.1    Drury, S.2    Fu, C.3    Qu, W.4    Taguchi, A.5    Lu, Y.6
  • 57
    • 0028851635 scopus 로고
    • The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system
    • Hori O, Brett J, Slattery T, Cao R, Zhang J, Chen JX et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J Biol Chem 1995 270: 25752 25761.
    • (1995) J Biol Chem , vol.270 , pp. 25752-25761
    • Hori, O.1    Brett, J.2    Slattery, T.3    Cao, R.4    Zhang, J.5    Chen, J.X.6
  • 58
    • 0034682315 scopus 로고    scopus 로고
    • Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases
    • Taguchi A, Blood DC, del Toro G, Canet A, Lee DC, Qu W et al. Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases. Nature 2000 405: 354 360.
    • (2000) Nature , vol.405 , pp. 354-360
    • Taguchi, A.1    Blood, D.C.2    Del Toro, G.3    Canet, A.4    Lee, D.C.5    Qu, W.6
  • 59
    • 0013615899 scopus 로고    scopus 로고
    • RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease
    • Yan SD, Chen X, Fu J, Chen M, Zhu H, Roher A et al. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature 1996 382: 685 691.
    • (1996) Nature , vol.382 , pp. 685-691
    • Yan, S.D.1    Chen, X.2    Fu, J.3    Chen, M.4    Zhu, H.5    Roher, A.6
  • 60
    • 0342646984 scopus 로고    scopus 로고
    • Interaction of the receptor for advanced glycation end products (RAGE) with transthyretin triggers nuclear transcription factor kB (NF-kB) activation
    • Sousa MM, Yan SD, Stern D, Saraiva MJ. Interaction of the receptor for advanced glycation end products (RAGE) with transthyretin triggers nuclear transcription factor kB (NF-kB) activation. Lab Invest 2000 80: 1101 1110.
    • (2000) Lab Invest , vol.80 , pp. 1101-1110
    • Sousa, M.M.1    Yan, S.D.2    Stern, D.3    Saraiva, M.J.4
  • 61
    • 10744229528 scopus 로고    scopus 로고
    • The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: A novel pathway for inflammatory cell recruitment
    • Chavakis T, Bierhaus A, Al-Fakhri N, Schneider D, Witte S, Linn T et al. The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment. J Exp Med 2003 198: 1507 1515.
    • (2003) J Exp Med , vol.198 , pp. 1507-1515
    • Chavakis, T.1    Bierhaus, A.2    Al-Fakhri, N.3    Schneider, D.4    Witte, S.5    Linn, T.6
  • 62
    • 0035460055 scopus 로고    scopus 로고
    • Series introduction: Multiligand receptors and human disease
    • Krieger M, Stern DM. Series introduction: multiligand receptors and human disease. J Clin Invest 2001 108: 645 647.
    • (2001) J Clin Invest , vol.108 , pp. 645-647
    • Krieger, M.1    Stern, D.M.2
  • 63
    • 0034795140 scopus 로고    scopus 로고
    • The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
    • Schmidt AM, Yan SD, Yan SF, Stern DM. The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J Clin Invest 2001 108: 949 955.
    • (2001) J Clin Invest , vol.108 , pp. 949-955
    • Schmidt, A.M.1    Yan, S.D.2    Yan, S.F.3    Stern, D.M.4
  • 64
    • 0034947508 scopus 로고    scopus 로고
    • Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice
    • Yamamoto Y, Kato I, Doi T, Yonekura H, Ohashi S, Takeuchi M et al. Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice. J Clin Invest 2001 108: 261 268.
    • (2001) J Clin Invest , vol.108 , pp. 261-268
    • Yamamoto, Y.1    Kato, I.2    Doi, T.3    Yonekura, H.4    Ohashi, S.5    Takeuchi, M.6
  • 65
    • 33750590947 scopus 로고    scopus 로고
    • RAGE control of diabetic nephropathy in a mouse model: Effects of RAGE gene disruption and administration of low-molecular weight heparin
    • Myint KM, Yamamoto Y, Doi T, Kato I, Harashima A, Yonekura H et al. RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low-molecular weight heparin. Diabetes 2006 55: 2510 2522.
    • (2006) Diabetes , vol.55 , pp. 2510-2522
    • Myint, K.M.1    Yamamoto, Y.2    Doi, T.3    Kato, I.4    Harashima, A.5    Yonekura, H.6
  • 66
    • 20844442808 scopus 로고    scopus 로고
    • Haplotype analysis of the RAGE gene: Identification of a haplotype marker for diabetic nephropathy in type 2 diabetes mellitus
    • Kankova K, Stejskalova A, Hertlova M, Znojil V. Haplotype analysis of the RAGE gene: identification of a haplotype marker for diabetic nephropathy in type 2 diabetes mellitus. Nephrol Dial Transplant 2005 20: 1093 1102.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 1093-1102
    • Kankova, K.1    Stejskalova, A.2    Hertlova, M.3    Znojil, V.4
  • 67
    • 14744274872 scopus 로고    scopus 로고
    • Polymorphisms of the receptor of advanced glycation endproducts (RAGE) and the development of nephropathy in type 1 diabetic patients
    • Prevost G, Fajardy I, Besmond C, Balkau B, Tichet J, Fontaine P et al. Polymorphisms of the receptor of advanced glycation endproducts (RAGE) and the development of nephropathy in type 1 diabetic patients. Diabetes Metab 2005 31: 35 9.
    • (2005) Diabetes Metab , vol.31 , pp. 35-9
    • Prevost, G.1    Fajardy, I.2    Besmond, C.3    Balkau, B.4    Tichet, J.5    Fontaine, P.6
  • 68
    • 85047694774 scopus 로고    scopus 로고
    • Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily
    • Bierhaus A, Haslbeck KM, Humpert PM, Liliensiek B, Dehmer T, Morcos M et al. Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily. J Clin Invest 2004 114: 1741 1751.
    • (2004) J Clin Invest , vol.114 , pp. 1741-1751
    • Bierhaus, A.1    Haslbeck, K.M.2    Humpert, P.M.3    Liliensiek, B.4    Dehmer, T.5    Morcos, M.6
  • 69
    • 42449157139 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGEs) and experimental diabetic neuropathy
    • Toth C, Rong LL, Yang C, Martinez J, Song F, Ramji N et al. Receptor for advanced glycation end products (RAGEs) and experimental diabetic neuropathy. Diabetes 2008 57: 1002 1017.
    • (2008) Diabetes , vol.57 , pp. 1002-1017
    • Toth, C.1    Rong, L.L.2    Yang, C.3    Martinez, J.4    Song, F.5    Ramji, N.6
  • 70
    • 0141960264 scopus 로고    scopus 로고
    • Phosphatidylinositol 3′-kinase-dependent activation of renal mesangial cell Ki-Ras and ERK by advanced glycation end products
    • Xu D, Kyriakis JM. Phosphatidylinositol 3′-kinase-dependent activation of renal mesangial cell Ki-Ras and ERK by advanced glycation end products. J Biol Chem 2003 278: 39349 39355.
    • (2003) J Biol Chem , vol.278 , pp. 39349-39355
    • Xu, D.1    Kyriakis, J.M.2
  • 71
    • 0028304625 scopus 로고
    • Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins
    • Yan SD, Schmidt AM, Anderson GM, Zhang J, Brett J, Zou YS et al. Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins. J Biol Chem 1994 269: 9889 9897.
    • (1994) J Biol Chem , vol.269 , pp. 9889-9897
    • Yan, S.D.1    Schmidt, A.M.2    Anderson, G.M.3    Zhang, J.4    Brett, J.5    Zou, Y.S.6
  • 73
    • 0141755110 scopus 로고    scopus 로고
    • Signal transduction pathways in mouse microglia N-11 cells activated by advanced glycation endproducts (AGEs)
    • Dukic-Stefanovic S, Gasic-Milenkovic J, Deuther-Conrad W, Munch G. Signal transduction pathways in mouse microglia N-11 cells activated by advanced glycation endproducts (AGEs). J Neurochem 2003 87: 44 55.
    • (2003) J Neurochem , vol.87 , pp. 44-55
    • Dukic-Stefanovic, S.1    Gasic-Milenkovic, J.2    Deuther-Conrad, W.3    Munch, G.4
  • 74
    • 0030910830 scopus 로고    scopus 로고
    • Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products
    • Li J, Schmidt AM. Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products. J Biol Chem 1997 272: 16498 16506.
    • (1997) J Biol Chem , vol.272 , pp. 16498-16506
    • Li, J.1    Schmidt, A.M.2
  • 75
    • 0035656173 scopus 로고    scopus 로고
    • Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB
    • Bierhaus A, Schiekofer S, Schwaninger M, Andrassy M, Humpert PM, Chen J et al. Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB. Diabetes 2001 50: 2792 2808.
    • (2001) Diabetes , vol.50 , pp. 2792-2808
    • Bierhaus, A.1    Schiekofer, S.2    Schwaninger, M.3    Andrassy, M.4    Humpert, P.M.5    Chen, J.6
  • 76
    • 0042317299 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products
    • Shanmugam N, Kim YS, Lanting L, Natarajan R. Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products. J Biol Chem 2003 278: 34834 34844.
    • (2003) J Biol Chem , vol.278 , pp. 34834-34844
    • Shanmugam, N.1    Kim, Y.S.2    Lanting, L.3    Natarajan, R.4
  • 77
    • 0029088742 scopus 로고
    • Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes
    • Schmidt AM, Hori O, Chen JX, Li JF, Crandall J, Zhang J et al. Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes. J Clin Invest 1995 96: 1395 1403.
    • (1995) J Clin Invest , vol.96 , pp. 1395-1403
    • Schmidt, A.M.1    Hori, O.2    Chen, J.X.3    Li, J.F.4    Crandall, J.5    Zhang, J.6
  • 78
    • 0035668462 scopus 로고    scopus 로고
    • The AGE-receptor in the pathogenesis of diabetic complications
    • Vlassara H. The AGE-receptor in the pathogenesis of diabetic complications. Diabetes Metab Res Rev 2001 17: 436 443.
    • (2001) Diabetes Metab Res Rev , vol.17 , pp. 436-443
    • Vlassara, H.1
  • 79
    • 0037133280 scopus 로고    scopus 로고
    • Advanced glycation end products activate endothelium through signal-transduction receptor RAGE: A mechanism for amplification of inflammatory responses
    • Basta G, Lazzerini G, Massaro M, Simoncini T, Tanganelli P, Fu C et al. Advanced glycation end products activate endothelium through signal-transduction receptor RAGE: a mechanism for amplification of inflammatory responses. Circulation 2002 105: 816 822.
    • (2002) Circulation , vol.105 , pp. 816-822
    • Basta, G.1    Lazzerini, G.2    Massaro, M.3    Simoncini, T.4    Tanganelli, P.5    Fu, C.6
  • 80
    • 3042668028 scopus 로고    scopus 로고
    • Enhanced expression of receptor for advanced glycation end products in chronic kidney disease
    • Hou FF, Ren H, Owen WF Jr., Guo ZJ, Chen PY, Schmidt AM et al. Enhanced expression of receptor for advanced glycation end products in chronic kidney disease. J Am Soc Nephrol 2004 15: 1889 1896.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1889-1896
    • Hou, F.F.1    Ren, H.2    Owen, Jr.W.F.3    Guo, Z.J.4    Chen, P.Y.5    Schmidt, A.M.6
  • 82
    • 44649098371 scopus 로고    scopus 로고
    • Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation
    • Linden E, Cai W, He JC, Xue C, Li Z, Winston J et al. Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation. Clin J Am Soc Nephrol 2008 3: 691 698.
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 691-698
    • Linden, E.1    Cai, W.2    He, J.C.3    Xue, C.4    Li, Z.5    Winston, J.6
  • 84
    • 0034682796 scopus 로고    scopus 로고
    • The receptor for advanced glycation end products is induced by the glycation products themselves and tumor necrosis factor-alpha through nuclear factor-kappa B, and by 17beta-estradiol through Sp-1 in human vascular endothelial cells
    • Tanaka N, Yonekura H, Yamagishi S, Fujimori H, Yamamoto Y, Yamamoto H. The receptor for advanced glycation end products is induced by the glycation products themselves and tumor necrosis factor-alpha through nuclear factor-kappa B, and by 17beta-estradiol through Sp-1 in human vascular endothelial cells. J Biol Chem 2000 275: 25781 25790.
    • (2000) J Biol Chem , vol.275 , pp. 25781-25790
    • Tanaka, N.1    Yonekura, H.2    Yamagishi, S.3    Fujimori, H.4    Yamamoto, Y.5    Yamamoto, H.6
  • 85
    • 0041315638 scopus 로고    scopus 로고
    • The receptor RAGE as a progression factor amplifying arachidonate- dependent inflammatory and proteolytic response in human atherosclerotic plaques: Role of glycemic control
    • Cipollone F, Iezzi A, Fazia M, Zucchelli M, Pini B, Cuccurullo C et al. The receptor RAGE as a progression factor amplifying arachidonate-dependent inflammatory and proteolytic response in human atherosclerotic plaques: role of glycemic control. Circulation 2003 108: 1070 1077.
    • (2003) Circulation , vol.108 , pp. 1070-1077
    • Cipollone, F.1    Iezzi, A.2    Fazia, M.3    Zucchelli, M.4    Pini, B.5    Cuccurullo, C.6
  • 87
    • 0031717894 scopus 로고    scopus 로고
    • Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts
    • Park L, Raman KG, Lee KJ, Lu Y, Ferran LJ Jr., Chow WS et al. Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts. Nat Med 1998 4: 1025 1031.
    • (1998) Nat Med , vol.4 , pp. 1025-1031
    • Park, L.1    Raman, K.G.2    Lee, K.J.3    Lu, Y.4    Ferran, Jr.L.J.5    Chow, W.S.6
  • 88
    • 0035715443 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice
    • Kislinger T, Tanji N, Wendt T, Qu W, Lu Y, Ferran LJ Jr. et al. Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice. Arterioscler Thromb Vasc Biol 2001 21: 905 910.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 905-910
    • Kislinger, T.1    Tanji, N.2    Wendt, T.3    Qu, W.4    Lu, Y.5    Ferran, Jr.L.J.6
  • 89
    • 30944454884 scopus 로고    scopus 로고
    • RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes
    • Wendt T, Harja E, Bucciarelli L, Qu W, Lu Y, Rong LL et al. RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes. Atherosclerosis 2006 185: 70 7.
    • (2006) Atherosclerosis , vol.185 , pp. 70-7
    • Wendt, T.1    Harja, E.2    Bucciarelli, L.3    Qu, W.4    Lu, Y.5    Rong, L.L.6
  • 90
    • 52749084063 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes
    • Soro-Paavonen A, Watson AM, Li J, Paavonen K, Koitka A, Calkin AC et al. Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes. Diabetes 2008 57: 2461 2469.
    • (2008) Diabetes , vol.57 , pp. 2461-2469
    • Soro-Paavonen, A.1    Watson, A.M.2    Li, J.3    Paavonen, K.4    Koitka, A.5    Calkin, A.C.6
  • 91
    • 38149078193 scopus 로고    scopus 로고
    • Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/-mice
    • Harja E, Bu DX, Hudson BI, Chang JS, Shen X, Hallam K et al. Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/-mice. J Clin Invest 2008 118: 183 194.
    • (2008) J Clin Invest , vol.118 , pp. 183-194
    • Harja, E.1    Bu, D.X.2    Hudson, B.I.3    Chang, J.S.4    Shen, X.5    Hallam, K.6
  • 92
    • 77953525199 scopus 로고    scopus 로고
    • Receptor for advanced glycation end-products (RAGE) regulation of adiposity and adiponectin is associated with atherogenesis in apo E-deficient mouse
    • in press).
    • Ueno H, Koyama H, Shoji T, Kurato M, Fukumoto S, Tanaka S et al. Receptor for advanced glycation end-products (RAGE) regulation of adiposity and adiponectin is associated with atherogenesis in apo E-deficient mouse. Atherosclerosis 2010 in press).
    • (2010) Atherosclerosis
    • Ueno, H.1    Koyama, H.2    Shoji, T.3    Kurato, M.4    Fukumoto, S.5    Tanaka, S.6
  • 93
    • 0037180531 scopus 로고    scopus 로고
    • RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice
    • Bucciarelli LG, Wendt T, Qu W, Lu Y, Lalla E, Rong LL et al. RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice. Circulation 2002 106: 2827 2835.
    • (2002) Circulation , vol.106 , pp. 2827-2835
    • Bucciarelli, L.G.1    Wendt, T.2    Qu, W.3    Lu, Y.4    Lalla, E.5    Rong, L.L.6
  • 94
    • 20844459438 scopus 로고    scopus 로고
    • Uremia accelerates both atherosclerosis and arterial calcification in apolipoprotein e knockout mice
    • Massy ZA, Ivanovski O, Nguyen-Khoa T, Angulo J, Szumilak D, Mothu N et al. Uremia accelerates both atherosclerosis and arterial calcification in apolipoprotein E knockout mice. J Am Soc Nephrol 2005 16: 109 116.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 109-116
    • Massy, Z.A.1    Ivanovski, O.2    Nguyen-Khoa, T.3    Angulo, J.4    Szumilak, D.5    Mothu, N.6
  • 96
    • 56649083783 scopus 로고    scopus 로고
    • A neutralizing antibody against receptor for advanced glycation end products (RAGE) reduces atherosclerosis in uremic mice
    • Bro S, Flyvbjerg A, Binder CJ, Bang CA, Denner L, Olgaard K et al. A neutralizing antibody against receptor for advanced glycation end products (RAGE) reduces atherosclerosis in uremic mice. Atherosclerosis 2008 201: 274 280.
    • (2008) Atherosclerosis , vol.201 , pp. 274-280
    • Bro, S.1    Flyvbjerg, A.2    Binder, C.J.3    Bang, C.A.4    Denner, L.5    Olgaard, K.6
  • 97
    • 0032741165 scopus 로고    scopus 로고
    • CDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein
    • Malherbe P, Richards JG, Gaillard H, Thompson A, Diener C, Schuler A et al. cDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein. Brain Res Mol Brain Res 1999 71: 159 170.
    • (1999) Brain Res Mol Brain Res , vol.71 , pp. 159-170
    • Malherbe, P.1    Richards, J.G.2    Gaillard, H.3    Thompson, A.4    Diener, C.5    Schuler, A.6
  • 98
    • 0037444761 scopus 로고    scopus 로고
    • Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury
    • Yonekura H, Yamamoto Y, Sakurai S, Petrova RG, Abedin MJ, Li H et al. Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury. Biochem J 2003 370: 1097 1109.
    • (2003) Biochem J , vol.370 , pp. 1097-1109
    • Yonekura, H.1    Yamamoto, Y.2    Sakurai, S.3    Petrova, R.G.4    Abedin, M.J.5    Li, H.6
  • 99
    • 0142122366 scopus 로고    scopus 로고
    • Tissue-specific expression patterns of the RAGE receptor and its soluble forms-A result of regulated alternative splicing?
    • Schlueter C, Hauke S, Flohr AM, Rogalla P, Bullerdiek J. Tissue-specific expression patterns of the RAGE receptor and its soluble forms-a result of regulated alternative splicing? Biochim Biophys Acta 2003 1630: 1 6.
    • (2003) Biochim Biophys Acta , vol.1630 , pp. 1-6
    • Schlueter, C.1    Hauke, S.2    Flohr, A.M.3    Rogalla, P.4    Bullerdiek, J.5
  • 100
    • 1142273309 scopus 로고    scopus 로고
    • Expression of a novel secreted splice variant of the receptor for advanced glycation end products (RAGE) in human brain astrocytes and peripheral blood mononuclear cells
    • Park IH, Yeon SI, Youn JH, Choi JE, Sasaki N, Choi IH et al. Expression of a novel secreted splice variant of the receptor for advanced glycation end products (RAGE) in human brain astrocytes and peripheral blood mononuclear cells. Mol Immunol 2004 40: 1203 1211.
    • (2004) Mol Immunol , vol.40 , pp. 1203-1211
    • Park, I.H.1    Yeon, S.I.2    Youn, J.H.3    Choi, J.E.4    Sasaki, N.5    Choi, I.H.6
  • 101
    • 8844263841 scopus 로고    scopus 로고
    • Splice variants of the receptor for advanced glycosylation end products (RAGE) in human brain
    • Ding Q, Keller JN. Splice variants of the receptor for advanced glycosylation end products (RAGE) in human brain. Neurosci Lett 2005 373: 67 72.
    • (2005) Neurosci Lett , vol.373 , pp. 67-72
    • Ding, Q.1    Keller, J.N.2
  • 102
    • 43249092154 scopus 로고    scopus 로고
    • Identification, classification, and expression of RAGE gene splice variants
    • Hudson BI, Carter AM, Harja E, Kalea AZ, Arriero M, Yang H et al. Identification, classification, and expression of RAGE gene splice variants. FASEB J 2008 22: 1572 1580.
    • (2008) FASEB J , vol.22 , pp. 1572-1580
    • Hudson, B.I.1    Carter, A.M.2    Harja, E.3    Kalea, A.Z.4    Arriero, M.5    Yang, H.6
  • 103
    • 67649344400 scopus 로고    scopus 로고
    • Alternative splicing of the murine receptor for advanced glycation end-products (RAGE) gene
    • Kalea AZ, Reiniger N, Yang H, Arriero M, Schmidt AM, Hudson BI. Alternative splicing of the murine receptor for advanced glycation end-products (RAGE) gene. FASEB J 2009 23: 1766 1774.
    • (2009) FASEB J , vol.23 , pp. 1766-1774
    • Kalea, A.Z.1    Reiniger, N.2    Yang, H.3    Arriero, M.4    Schmidt, A.M.5    Hudson, B.I.6
  • 105
    • 33749327828 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products is involved in impaired angiogenic response in diabetes
    • Shoji T, Koyama H, Morioka T, Tanaka S, Kizu A, Motoyama K et al. Receptor for advanced glycation end products is involved in impaired angiogenic response in diabetes. Diabetes 2006 55: 2245 2255.
    • (2006) Diabetes , vol.55 , pp. 2245-2255
    • Shoji, T.1    Koyama, H.2    Morioka, T.3    Tanaka, S.4    Kizu, A.5    Motoyama, K.6
  • 106
    • 18344376046 scopus 로고    scopus 로고
    • Soluble levels of receptor for advanced glycation endproducts (sRAGE) and coronary artery disease: The next C-reactive protein?
    • Hudson BI, Harja E, Moser B, Schmidt AM. Soluble levels of receptor for advanced glycation endproducts (sRAGE) and coronary artery disease: the next C-reactive protein? Arterioscler Thromb Vasc Biol 2005 25: 879 882.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 879-882
    • Hudson, B.I.1    Harja, E.2    Moser, B.3    Schmidt, A.M.4
  • 107
    • 9644302477 scopus 로고    scopus 로고
    • Purification and characterization of mouse soluble receptor for advanced glycation end products (sRAGE)
    • Hanford LE, Enghild JJ, Valnickova Z, Petersen SV, Schaefer LM, Schaefer TM et al. Purification and characterization of mouse soluble receptor for advanced glycation end products (sRAGE). J Biol Chem 2004 279: 50019 50024.
    • (2004) J Biol Chem , vol.279 , pp. 50019-50024
    • Hanford, L.E.1    Enghild, J.J.2    Valnickova, Z.3    Petersen, S.V.4    Schaefer, L.M.5    Schaefer, T.M.6
  • 108
    • 54049108485 scopus 로고    scopus 로고
    • A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)
    • Raucci A, Cugusi S, Antonelli A, Barabino SM, Monti L, Bierhaus A et al. A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10). FASEB J 2008 22: 3716 3727.
    • (2008) FASEB J , vol.22 , pp. 3716-3727
    • Raucci, A.1    Cugusi, S.2    Antonelli, A.3    Barabino, S.M.4    Monti, L.5    Bierhaus, A.6
  • 109
    • 58149101483 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases
    • Zhang L, Bukulin M, Kojro E, Roth A, Metz VV, Fahrenholz F et al. Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases. J Biol Chem 2008 283: 35507 35516.
    • (2008) J Biol Chem , vol.283 , pp. 35507-35516
    • Zhang, L.1    Bukulin, M.2    Kojro, E.3    Roth, A.4    Metz, V.V.5    Fahrenholz, F.6
  • 110
    • 33845681592 scopus 로고    scopus 로고
    • Soluble receptor for advanced glycation end products triggers a proinflammatory cytokine cascade via beta2 integrin Mac-1
    • Pullerits R, Brisslert M, Jonsson IM, Tarkowski A. Soluble receptor for advanced glycation end products triggers a proinflammatory cytokine cascade via beta2 integrin Mac-1. Arthritis Rheum 2006 54: 3898 3907.
    • (2006) Arthritis Rheum , vol.54 , pp. 3898-3907
    • Pullerits, R.1    Brisslert, M.2    Jonsson, I.M.3    Tarkowski, A.4
  • 112
    • 61449143384 scopus 로고    scopus 로고
    • Levels of soluble receptor for AGE are cross-sectionally associated with cardiovascular disease in type 1 diabetes, and this association is partially mediated by endothelial and renal dysfunction and by low-grade inflammation: The EURODIAB Prospective Complications Study
    • Nin JW, Ferreira I, Schalkwijk CG, Prins MH, Chaturvedi N, Fuller JH et al. Levels of soluble receptor for AGE are cross-sectionally associated with cardiovascular disease in type 1 diabetes, and this association is partially mediated by endothelial and renal dysfunction and by low-grade inflammation: the EURODIAB Prospective Complications Study. Diabetologia 2009 52: 705 714.
    • (2009) Diabetologia , vol.52 , pp. 705-714
    • Nin, J.W.1    Ferreira, I.2    Schalkwijk, C.G.3    Prins, M.H.4    Chaturvedi, N.5    Fuller, J.H.6
  • 113
    • 61449087504 scopus 로고    scopus 로고
    • Serum endogenous secretory RAGE level is an independent risk factor for the progression of carotid atherosclerosis in type 1 diabetes
    • Katakami N, Matsuhisa M, Kaneto H, Matsuoka TA, Sakamoto K, Yasuda T et al. Serum endogenous secretory RAGE level is an independent risk factor for the progression of carotid atherosclerosis in type 1 diabetes. Atherosclerosis 2009 204: 288 292.
    • (2009) Atherosclerosis , vol.204 , pp. 288-292
    • Katakami, N.1    Matsuhisa, M.2    Kaneto, H.3    Matsuoka, T.A.4    Sakamoto, K.5    Yasuda, T.6
  • 114
    • 36849085490 scopus 로고    scopus 로고
    • RAGE and soluble RAGE: Potential therapeutic targets for cardiovascular diseases
    • Koyama H, Yamamoto H, Nishizawa Y. RAGE and soluble RAGE: potential therapeutic targets for cardiovascular diseases. Mol Med 2007 13: 625 635.
    • (2007) Mol Med , vol.13 , pp. 625-635
    • Koyama, H.1    Yamamoto, H.2    Nishizawa, Y.3
  • 116
    • 33644808985 scopus 로고    scopus 로고
    • Plasma level of endogenous secretory RAGE is associated with components of the metabolic syndrome and atherosclerosis
    • Koyama H, Shoji T, Yokoyama H, Motoyama K, Mori K, Fukumoto S et al. Plasma level of endogenous secretory RAGE is associated with components of the metabolic syndrome and atherosclerosis. Arterioscler Thromb Vasc Biol 2005 25: 2587 2593.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2587-2593
    • Koyama, H.1    Shoji, T.2    Yokoyama, H.3    Motoyama, K.4    Mori, K.5    Fukumoto, S.6
  • 117
    • 33947386181 scopus 로고    scopus 로고
    • Soluble RAGE but not endogenous secretory RAGE is associated with albuminuria in patients with type 2 diabetes
    • Humpert PM, Djuric Z, Kopf S, Rudofsky G, Morcos M, Nawroth PP et al. Soluble RAGE but not endogenous secretory RAGE is associated with albuminuria in patients with type 2 diabetes. Cardiovasc Diabetol 2007 6: 9.
    • (2007) Cardiovasc Diabetol , vol.6 , pp. 9
    • Humpert, P.M.1    Djuric, Z.2    Kopf, S.3    Rudofsky, G.4    Morcos, M.5    Nawroth, P.P.6
  • 118
    • 32844466467 scopus 로고    scopus 로고
    • Decreased endogenous secretory advanced glycation end product receptor in type 1 diabetic patients: Its possible association with diabetic vascular complications
    • Katakami N, Matsuhisa M, Kaneto H, Matsuoka TA, Sakamoto K, Nakatani Y et al. Decreased endogenous secretory advanced glycation end product receptor in type 1 diabetic patients: its possible association with diabetic vascular complications. Diabetes Care 2005 28: 2716 2721.
    • (2005) Diabetes Care , vol.28 , pp. 2716-2721
    • Katakami, N.1    Matsuhisa, M.2    Kaneto, H.3    Matsuoka, T.A.4    Sakamoto, K.5    Nakatani, Y.6
  • 119
    • 51749105625 scopus 로고    scopus 로고
    • Endogenous secretory RAGE but not soluble RAGE is associated with carotid atherosclerosis in type 1 diabetes patients
    • Katakami N, Matsuhisa M, Kaneto H, Matsuoka TA, Sakamoto K, Yasuda T et al. Endogenous secretory RAGE but not soluble RAGE is associated with carotid atherosclerosis in type 1 diabetes patients. Diab Vasc Dis Res 2008 5: 190 197.
    • (2008) Diab Vasc Dis Res , vol.5 , pp. 190-197
    • Katakami, N.1    Matsuhisa, M.2    Kaneto, H.3    Matsuoka, T.A.4    Sakamoto, K.5    Yasuda, T.6
  • 120
    • 70349525016 scopus 로고    scopus 로고
    • Increased glycated albumin and decreased esRAGE levels are related to angiographic severity and extent of coronary artery disease in patients with type 2 diabetes
    • Lu L, Pu LJ, Zhang Q, Wang LJ, Kang S, Zhang RY et al. Increased glycated albumin and decreased esRAGE levels are related to angiographic severity and extent of coronary artery disease in patients with type 2 diabetes. Atherosclerosis 2009 206: 540 545.
    • (2009) Atherosclerosis , vol.206 , pp. 540-545
    • Lu, L.1    Pu, L.J.2    Zhang, Q.3    Wang, L.J.4    Kang, S.5    Zhang, R.Y.6
  • 121
    • 33947408459 scopus 로고    scopus 로고
    • Association between serum levels of soluble receptor for advanced glycation end products and circulating advanced glycation end products in type 2 diabetes
    • Tan KC, Shiu SW, Chow WS, Leng L, Bucala R, Betteridge DJ. Association between serum levels of soluble receptor for advanced glycation end products and circulating advanced glycation end products in type 2 diabetes. Diabetologia 2006 49: 2756 2762.
    • (2006) Diabetologia , vol.49 , pp. 2756-2762
    • Tan, K.C.1    Shiu, S.W.2    Chow, W.S.3    Leng, L.4    Bucala, R.5    Betteridge, D.J.6
  • 123
    • 37049007394 scopus 로고    scopus 로고
    • Endogenous secretory receptor for advanced glycation end-products and cardiovascular disease in end-stage renal disease
    • Nishizawa Y, Koyama H. Endogenous secretory receptor for advanced glycation end-products and cardiovascular disease in end-stage renal disease. J Ren Nutr 2008 18: 76 82.
    • (2008) J Ren Nutr , vol.18 , pp. 76-82
    • Nishizawa, Y.1    Koyama, H.2
  • 124
    • 33847043439 scopus 로고    scopus 로고
    • Pregnancy-associated plasma protein a and soluble receptor for advanced glycation end products after kidney transplantation
    • Kalousova M, Bartosova K, Zima T, Skibova J, Teplan V, Viklicky O. Pregnancy-associated plasma protein a and soluble receptor for advanced glycation end products after kidney transplantation. Kidney Blood Press Res 2007 30: 31 7.
    • (2007) Kidney Blood Press Res , vol.30 , pp. 31-7
    • Kalousova, M.1    Bartosova, K.2    Zima, T.3    Skibova, J.4    Teplan, V.5    Viklicky, O.6
  • 125
    • 74449089368 scopus 로고    scopus 로고
    • Circulating soluble receptor of advanced glycation end product inversely correlates with atherosclerosis in patients with chronic kidney disease
    • Basta G, Leonardis D, Mallamaci F, Cutrupi S, Pizzini P, Gaetano L et al. Circulating soluble receptor of advanced glycation end product inversely correlates with atherosclerosis in patients with chronic kidney disease. Kidney Int 2010 77: 225 231.
    • (2010) Kidney Int , vol.77 , pp. 225-231
    • Basta, G.1    Leonardis, D.2    Mallamaci, F.3    Cutrupi, S.4    Pizzini, P.5    Gaetano, L.6
  • 126
    • 33847608713 scopus 로고    scopus 로고
    • Low circulating endogenous secretory receptor for AGEs predicts cardiovascular mortality in patients with end-stage renal disease
    • Koyama H, Shoji T, Fukumoto S, Shinohara K, Emoto M, Mori K et al. Low circulating endogenous secretory receptor for AGEs predicts cardiovascular mortality in patients with end-stage renal disease. Arterioscler Thromb Vasc Biol 2007 27: 147 153.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 147-153
    • Koyama, H.1    Shoji, T.2    Fukumoto, S.3    Shinohara, K.4    Emoto, M.5    Mori, K.6
  • 128
    • 33751509416 scopus 로고    scopus 로고
    • Circulating soluble receptor for advanced glycation end products is inversely associated with glycemic control and S100A12 protein
    • Basta G, Sironi AM, Lazzerini G, Del Turco S, Buzzigoli E, Casolaro A et al. Circulating soluble receptor for advanced glycation end products is inversely associated with glycemic control and S100A12 protein. J Clin Endocrinol Metab 2006 91: 4628 4634.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 4628-4634
    • Basta, G.1    Sironi, A.M.2    Lazzerini, G.3    Del Turco, S.4    Buzzigoli, E.5    Casolaro, A.6
  • 130
    • 28444472740 scopus 로고    scopus 로고
    • Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy
    • Forbes JM, Thorpe SR, Thallas-Bonke V, Pete J, Thomas MC, Deemer ER et al. Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy. J Am Soc Nephrol 2005 16: 2363 2372.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2363-2372
    • Forbes, J.M.1    Thorpe, S.R.2    Thallas-Bonke, V.3    Pete, J.4    Thomas, M.C.5    Deemer, E.R.6
  • 131
    • 4644342944 scopus 로고    scopus 로고
    • Thiazolidinediones reduce endothelial expression of receptors for advanced glycation end products
    • Marx N, Walcher D, Ivanova N, Rautzenberg K, Jung A, Friedl R et al. Thiazolidinediones reduce endothelial expression of receptors for advanced glycation end products. Diabetes 2004 53: 2662 2668.
    • (2004) Diabetes , vol.53 , pp. 2662-2668
    • Marx, N.1    Walcher, D.2    Ivanova, N.3    Rautzenberg, K.4    Jung, A.5    Friedl, R.6
  • 132
    • 0036884617 scopus 로고    scopus 로고
    • Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin
    • Okamoto T, Yamagishi S, Inagaki Y, Amano S, Koga K, Abe R et al. Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin. FASEB J 2002 16: 1928 1930.
    • (2002) FASEB J , vol.16 , pp. 1928-1930
    • Okamoto, T.1    Yamagishi, S.2    Inagaki, Y.3    Amano, S.4    Koga, K.5    Abe, R.6
  • 134
    • 34547659641 scopus 로고    scopus 로고
    • Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes
    • Tan KC, Chow WS, Tso AW, Xu A, Tse HF, Hoo RL et al. Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes. Diabetologia 2007 50: 1819 1825.
    • (2007) Diabetologia , vol.50 , pp. 1819-1825
    • Tan, K.C.1    Chow, W.S.2    Tso, A.W.3    Xu, A.4    Tse, H.F.5    Hoo, R.L.6
  • 135
    • 77049119450 scopus 로고    scopus 로고
    • Effects of atorvastatin on serum soluble receptors for advanced glycation end-products in type 2 diabetes
    • Tam HL, Shiu SW, Wong Y, Chow WS, Betteridge DJ, Tan KC. Effects of atorvastatin on serum soluble receptors for advanced glycation end-products in type 2 diabetes. Atherosclerosis 2009 209: 173 177.
    • (2009) Atherosclerosis , vol.209 , pp. 173-177
    • Tam, H.L.1    Shiu, S.W.2    Wong, Y.3    Chow, W.S.4    Betteridge, D.J.5    Tan, K.C.6
  • 136
    • 33746363247 scopus 로고    scopus 로고
    • Plasma sRAGE is independently associated with urinary albumin excretion in type 2 diabetes
    • Humpert PM, Kopf S, Djuric Z, Wendt T, Morcos M, Nawroth PP et al. Plasma sRAGE is independently associated with urinary albumin excretion in type 2 diabetes. Diabetes Care 2006 29: 1111 1113.
    • (2006) Diabetes Care , vol.29 , pp. 1111-1113
    • Humpert, P.M.1    Kopf, S.2    Djuric, Z.3    Wendt, T.4    Morcos, M.5    Nawroth, P.P.6
  • 137
    • 34547830269 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products - Soluble form and gene polymorphisms in chronic haemodialysis patients
    • DOI 10.1093/ndt/gfm050
    • Kalousova M, Jachymova M, Mestek O, Hodkova M, Kazderova M, Tesar V et al. Receptor for advanced glycation end products-soluble form and gene polymorphisms in chronic haemodialysis patients. Nephrol Dial Transplant 2007 20: 2020 2026. (Pubitemid 47244776)
    • (2007) Nephrology Dialysis Transplantation , vol.22 , Issue.7 , pp. 2020-2026
    • Kalousova, M.1    Jachymova, M.2    Oto, M.3    Hodkova, M.4    Kazderova, M.5    Tesar, V.6    Zima, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.