Mechanical implications of estrogen supplementation in early postmenopausal women

Journal of Bone and Mineral Research

Volumn 25, Issue 6, 2010, Pages 1406-1414

  Wehrli, Felix W ^a   Rajapakse, Chamith S ^a   Magland, Jeremy F ^a   Snyder, Peter J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cortical bone; Estrogen; Finite element; Menopause; MRI; Structure; Trabecular bone

Indexed keywords

ESTRADIOL;

ADULT; ARTICLE; BIOMECHANICS; BONE PLATE; CONTROLLED STUDY; CORTICAL BONE; ELASTICITY; FEMALE; HUMAN; JOINT STIFFNESS; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTMENOPAUSE; RADIUS; SHEAR STRESS; SUPPLEMENTATION; THREE DIMENSIONAL IMAGING; TIBIA; TRABECULAR BONE;

BIOMECHANICS; DIETARY SUPPLEMENTS; ELASTIC MODULUS; ESTROGENS; FEMALE; FINITE ELEMENT ANALYSIS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MIDDLE AGED; POSTMENOPAUSE;

EID: 77953511836     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.33     Document Type: Article

References (52)

1. Seeman E, Delmas PD. Bone quality-the material and structural basis of bone strength and fragility. N Engl J Med 2006;354:2250-61. (Pubitemid 43788139)
2. Paschalis EP, Boskey AL, Kassem M, Eriksen EF. Effect of hormone replacement therapy on bone quality in early postmenopausal women. J Bone Miner Res 2003;18:955-9. (Pubitemid 37294931)
3. Recker RR, Barger-Lux MJ. The elusive concept of bone quality. Curr Osteoporos Rep 2004;2:97-100.
4. Sarkar S, Mitlak BH, Wong M, Stock JL, Black DM, Harper KD. Relationships between bone mineral density and incident vertebral fracture risk with raloxifene therapy. J Bone Miner Res 2002;17:1-10. (Pubitemid 33150990)
5. Genant HK, Jiang Y. Advanced imaging assessment of bone quality. Ann N Y Acad Sci 2006;1068:410-28. (Pubitemid 43824171)
6. Wehrli FW. Structural and functional assessment of trabecular and cortical bone by micro magnetic resonance imaging. J Magn Reson Imaging 2007;25:390-409. (Pubitemid 46204587)
7. Bouxsein ML. Technology insight: noninvasive assessment of bone strength in osteoporosis. Nat Clin Pract Rheumatol 2008;4:310-8.
8. Hwang SN, Wehrli FW, Williams JL. Probability-based structural parameters from 3D NMR images as predictors of trabecular bone strength. Medical Physics 1997;24:1255-1261.
9. Ulrich D, van Rietbergen B, Laib A, Ruegsegger P. The ability of three-dimensional structural indices to reflect mechanical aspects of trabecular bone. Bone 1999;25:55-60. (Pubitemid 29322061)
10. Genant HK, Engelke K, Prevrhal S. Advanced CT bone imaging in osteoporosis. Rheumatology (Oxford) 2008;47 (Suppl 4): iv9-16.
11. Techawiboonwong A, Song HK, Leonard MB, Wehrli FW. Cortical bone water: in vivo quantification with ultrashort echo-time MR imaging. Radiology 2008;248:824-33.
12. Link TM, Majumdar S, Augat P, et al. In vivo high resolution MRI of the calcaneus: differences in trabecular structure in osteoporosis patients. Journal of Bone and Mineral Research 1998;13:1175-82.
13. Wehrli FW, Gomberg BR, Saha PK, Song HK, Hwang SN, Snyder PJ. Digital topological analysis of in vivo magnetic resonance micro-images of trabecular bone reveals structural implications of osteoporosis. J Bone Miner Res 2001;16:1520-31.
14. Boutry N, Cortet B, Dubois P, Marchandise X, Cotten A. Trabecular bone structure of the calcaneus: preliminary in vivo MR imaging assessment in men with osteoporosis. Radiology 2003;227:708-17. (Pubitemid 36583025)
15. Boutroy S, Bouxsein ML, Munoz F, Delmas PD. In Vivo Assessment of Trabecular Bone Microarchitecture by High-Resolution Peripheral Quantitative Computed Tomography. J Clin Endocrinol Metab 2005;90:6805-15.
16. Khosla S, Riggs BL, Atkinson EJ, et al. Effects of sex and age on bone microstructure at the ultradistal radius: a population-based noninvasive in vivo assessment. J Bone Miner Res 2006;21:124-31. (Pubitemid 43023234)
17. Chesnut CH 3rd, Majumdar S, Newitt DC, et al. Effects of salmon calcitonin on trabecular microarchitecture as determined by magnetic resonance imaging: results from the QUEST study. J Bone Miner Res 2005;20:1548-61.
18. Benito M, Vasilic B, Wehrli FW, et al. Effect of testosterone replacement on bone architecture in hypogonadal men. J Bone Miner Res 2005;20:1785-91. (Pubitemid 41361879)
19. Graeff C, Timm W, Nickelsen TN, et al. Monitoring Teriparatide associated Changes in Vertebral Microstructure by High-Resolution Computed Tomography in vivo: Results from the EUROFORS study. J Bone Miner Res 2007;22:1426-33. (Pubitemid 351339687)
20. Wehrli FW, Ladinsky GA, Jones C, et al. In vivo magnetic resonance detects rapid remodeling changes in the topology of the trabecular bone network after menopause and the protective effect of estradiol. J Bone Miner Res 2008;23:730-40.
21. Liu XS, Sajda P, Saha PK, Wehrli FW, Guo XE. Quantification of the roles of trabecular microarchitecture and trabecular type in determining the elastic modulus of human trabecular bone. J Bone Miner Res 2006;21:1608-17. (Pubitemid 44484606)
22. Ciarelli TE, Fyhrie DP, Schaffler MB, Goldstein SA. Variations in three-dimensional cancellous bone architecture of the proximal femur in female hip fractures and in controls. J Bone Miner Res 2000;15:32-40.
23. Keaveny TM, Morgan EF, Niebur GL, Yeh OC. Biomechanics of trabecular bone. Annu Rev Biomed Eng 2001;3:307-33.
24. Kabel J, van Rietbergen B, Dalstra M, Odgaard A, Huiskes R. The role of an effective isotropic tissue modulus in the elastic properties of cancellous bone. J Biomech 1999;32:673-80. (Pubitemid 29322086)
25. Rajapakse CS, Magland J, Zhang XH, et al. Implications of noise and resolution on mechanical properties of trabecular bone estimated by image-based finite-element analysis. J Orthop Res. 2009.
26. Muller R, Ruegsegger P. Analysis of mechanical properties of cancellous bone under conditions of simulated bone atrophy. J Biomech 1996;29:1053-60. (Pubitemid 26199772)
27. van Rietbergen B, Majumdar S, Newitt D, MacDonald B. High-resolution MRI and micro-FE for the evaluation of changes in bone mechanical properties during longitudinal clinical trials: application to calcaneal bone in postmenopausal women after one year of idoxifene treatment. Clin Biomech (Bristol, Avon) 2002;17:81-8. (Pubitemid 34097755)
28. Zhang XH, Liu XS, Vasilic B, et al. In vivo microMRI-based finite element and morphological analyses of tibial trabecular bone in eugonadal and hypogonadal men before and after testosterone treatment. J Bone Miner Res 2008;23:1426-34.
29. Song HK, Wehrli FW. In vivo micro-imaging using alternating navigator echoes with applications to cancellous bone structural analysis. Magnetic Resonance in Medicine 1999;41:947-953.
30. Ladinsky GA, Vasilic B, Popescu AM, et al. Trabecular Structure Quantified With the MRI-Based Virtual Bone Biopsy in Postmenopausal Women Contributes to Vertebral Deformity Burden Independent of Areal Vertebral BMD. J Bone Miner Res 2008;23:64-74.
31. Vasilic B, Wehrli FW. A novel local thresholding algorithm for trabecular bone volume fraction mapping in the limited spatial resolution regime of in-vivo MRI. IEEE Trans Med Imaging 2005;24:1574-1585. (Pubitemid 41812025)
32. Rajapakse CS, Magland JF, Wald MJ, et al. Estimation of Relative Stiffness Contributions of Cortical and Trabecular Compartments by MRI-based Finite Element Analysis. Journal of Bone and Mineral Research 2008;23:S366-S366.
33. Magland JF, Jones CE, Leonard MB, Wehrli FW. Retrospective 3D registration of trabecular bone MR images for longitudinal studies. J Magn Reson Imaging 2009;29:118-26.
34. Van Rietbergen B, Odgaard A, Kabel J, Huiskes R. Direct mechanics assessment of elastic symmetries and properties of trabecular bone architecture. Journal of Biomechanics 1996;29:1653-1657. (Pubitemid 26381880)
35. Hollister SJ, Brennan JM, Kikuchi N. A homogenization sampling procedure for calculating trabecular bone effective stiffness and tissue level stress. J Biomech 1994;27:433-44.
36. Macneil JA, Boyd SK. Bone strength at the distal radius can be estimated from high-resolution peripheral quantitative computed tomography and the finite element method. Bone 2008;42:1203-13.
37. Gomberg BG, Saha PK, Song HK, Hwang SN, Wehrli FW. Application of topological analysis to magnetic resonance images of human trabecular bone. IEEE Transactions on Medical Imaging 2000;19:166-174.
38. Magland JF, Wehrli FW. Trabecular bone structure analysis in the limited spatial resolution regime of in vivo MRI. Acad Radiol 2008;15:1482-93.
39. Manzanera A, Bernard TM, Preteux P, Longuet B. N-dimensional skeletonization: a unified mathematical framework. Journal of Electronic Imaging 2002;11:25-37. (Pubitemid 34278370)
40. MacNeil JA, Boyd SK. Load distribution and the predictive power of morphological indices in the distal radius and tibia by high resolution peripheral quantitative computed tomography. Bone 2007;41:129-37.
41. Akhter MP, Lappe JM, Davies KM, Recker RR. Transmenopausal changes in the trabecular bone structure. Bone 2007;41:111-6.
42. Jee WS, Tian XY. The benefit of combining non-mechanical agents with mechanical loading: a perspective based on the Utah Paradigm of Skeletal Physiology. J Musculoskelet Neuronal Interact 2005;5:110-8.
43. Westerlind KC, Wronski TJ, Ritman EL, et al. Estrogen regulates the rate of bone turnover but bone balance in ovariectomized rats is modulated by prevailing mechanical strain. Proc Natl Acad Sci U S A 1997;94:4199-204.
44. Tromp AM, Bravenboer N, Tanck E, et al. Additional weight bearing during exercise and estrogen in the rat: the effect on bone mass, turnover, and structure. Calcif Tissue Int 2006;79:404-15. (Pubitemid 46020452)
45. Vedi S, Croucher PI, Garrahan NJ, Compston JE. Effects of hormone replacement therapy on cancellous bone microstructure in postmenopausal women. Bone 1996;19:69-72. (Pubitemid 26318748)
46. Khastgir G, Studd J, Holland N, Alaghband-Zadeh J, Fox S, Chow J. Anabolic effect of estrogen replacement on bone in postmenopausal women with osteoporosis: histomorphometric evidence in a longitudinal study. J Clin Endocrinol Metab 2001;86:289-95. (Pubitemid 32109808)
47. Vedi S, Bell KL, Loveridge N, Garrahan N, Purdie DW, Compston JE. The effects of hormone replacement therapy on cortical bone in postmenopausal women. A histomorphometric study. Bone 2003;33:330-4.
48. Gourion-Arsiquaud S, Faibish D, Myers E, et al. Use of FTIR spectroscopic imaging to identify parameters associated with fragility fracture. J Bone Miner Res 2009;24:1565-71.
49. Boutroy S, Van Rietbergen B, Sornay-Rendu E, Munoz F, Bouxsein ML, Delmas PD. Finite element analysis based on in vivo HR-pQCT images of the distal radius is associated with wrist fracture in postmenopausal women. J Bone Miner Res 2008;23:392-9. (Pubitemid 351304669)
50. Macneil JA, Boyd SK. Accuracy of high-resolution peripheral quantitative computed tomography for measurement of bone quality. Med Eng Phys. 2007;
51. Magland JF, Rajapakse CS, Wald MJ, et al. 2008: Grayscale MR image based finite element mechanical modeling of trabecular bone at in vivo resolution 30th Annual Meeting of the American Society for Bone and Mineral Research. ASBMR, Montréal, Quebéc; Canada: pp S310.
52. Pistoia W, van Rietbergen B, Lochmuller EM, Lill CA, Eckstein F, Ruegsegger P. 2002; Estimation of distal radius failure load with micro-finite element analysis models based on three-dimensional peripheral quantitative computed tomography images. Bone 30:842-8. (Pubitemid 34616011)