A novel local thresholding algorithm for trabecular bone volume fraction mapping in the limited spatial resolution regime of in vivo MRI

IEEE Transactions on Medical Imaging

Volumn 24, Issue 12, 2005, Pages 1574-1585

  Vasilic, Branimir ^a   Wehrli, Felix W ^b  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Image segmentation; Local; Threshold; Trabecular bone

Indexed keywords

BONE; HISTOLOGY; IMAGE SEGMENTATION; IMAGING SYSTEMS; MAGNETIC RESONANCE IMAGING; ROBUSTNESS (CONTROL SYSTEMS); SIGNAL TO NOISE RATIO; VOLUME FRACTION;

IMAGE NOISE; LOCAL; THRESHOLD; TRABECULAR BONE;

ALGORITHMS;

ALGORITHM; ARTICLE; ARTIFICIAL INTELLIGENCE; AUTOMATED PATTERN RECOGNITION; CLINICAL TRIAL; COMPUTER ASSISTED DIAGNOSIS; HISTOLOGY; HUMAN; IMAGE ENHANCEMENT; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; ORGAN SIZE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; THREE DIMENSIONAL IMAGING; TIBIA;

ALGORITHMS; ARTIFICIAL INTELLIGENCE; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MAGNETIC RESONANCE IMAGING; ORGAN SIZE; PATTERN RECOGNITION, AUTOMATED; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TIBIA;

EID: 29144441427     PISSN: 02780062     EISSN: None     Source Type: Journal    
DOI: 10.1109/TMI.2005.859192     Document Type: Article

References (18)

1. J. Wolff, Das Gesetz der Transformation der Knochen. Berlin, Germany: A. Hirschwald, 1892.
2. H. Roesler, "The history of some fundamental concepts in bone biomechanics," J. Biomech., vol. 20, pp. 1025-1034, 1987.
3. S. C. Cowin, "Wolff s law of trabecular bone architecture at remodeling equilibrium," J. Biomech. Eng., vol. 108, pp. 83-88, 1986.
4. B. L. Riggs and L. J. Melton, III, Eds., Osteoporosis: Etiology, Diagnosis, and Management, 2nd ed. Philadelphia, PA: Lippincott - Raven, 1995.
5. S. Majumdar, "Magnetic resonance imaging of trabecular bone structure," Topics Magn. Reson. Imag., vol. 13, no. 5, pp. 323-334.
6. F. W. Wehrli, P. K. Saha, B. R. Gomberg, and H. K. Song, "Noninvasive assessment of bone architecture by magnetic resonance micro-imaging-based virtual bone biopsy," Proc. IEEE, vol. 91, no. 10, pp. 1520-1542, Oct. 2003.
7. J. Ma, F. W. Wehrli, and H. K. Song, "Fast 3D large-angle spin-echo imaging (3D FLASH)," Magn. Reson. Med., vol. 35, pp. 903-910, 1996.
8. S. N. Hwang and F. W. Wehrli, "Estimating voxel volume fractions of trabecular bone on the basis of magnetic resonance images acquired in vivo," Int. J. Imag. Syst. Technol., vol. 10, pp. 186-198, 1999.
9. M. Sezgin and B. Sankur, "Survey over image thresholding techniques and quantitative performance evaluation," J. Electron. Imag., vol. 13, no. 1, pp. 146-165, 2004.
10. S. N. Hwang and F. W. Wehrli, "A fast method for estimating voxel bone volume fractions from in vivo high-resolution MR images," in Proc. 2003 Annu. Meeting Int. Soc. Magnetic Resonance in Medicine, Glasgow, U.K., 2001, p. 844.
11. R. M. Henkelman, "Measurement of signal intensities in the presence of noise in MR images," Med. Phys., vol. 12, no. 2, pp. 222-223, 1985.
12. H. Gudbjartsson and S. Patz, "The rician distribution of noisy MRI data," Magn. Reson. Med., vol. 34, pp. 910-914, 1995.
13. E. M. Haacke, R. W. Brown, M. R. Thompson, and R. Venkateshan, "Magnetic resonance imaging," Physical Principles and Sequence Design, pp. 240-247, 1999.
14. H. K. Song and F. W. Wehrli, "In vivo mirco-imaging using alternating navigator echoes with applications to cancelous bone structural analysis," Magn. Reson. Med., vol. 41, pp. 974-953, 1999.
15. S. N. Hwang and F. W. Wehrli, "Subvoxel processing: A method for reducing partial volume blurring with application to in vivo MR images of trabecular bone," Magn. Reson. Med., vol. 47, pp. 948-957, 2002.
16. B. R. Gomberg, P. K. Saha, H. K. Song, S. N. Hwang, and F. W. Wehrli, "Topological analysis of trabecular bone MR images," IEEE Trans. Med. Imag., vol. 19, no. 3, pp. 166-174, Mar 2000.
17. P. K. Saha and F. W. Wehrli, "Measurement of trabecular bone thickness in the limited resolution regime of in vivo MRI by fuzzy distance transform," IEEE Trans. Med. Imag., vol. 23, pp. 53-62, Jan. 2004.
18. M. Benito, B. Vasilić, F. W. Wehrli, B. Bunker, M. Wald, B. Gomberg, A. C. Wright, B. Zemel, A. Cucchiara, and P. J. Snyder, "Effect of testosterone replacement on trabecular architecture in hypogonadal men," J. Bone Mineral Res., to be published.