-
1
-
-
0025782910
-
CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase
-
Yen TJ, Compton DA, Wise D, Zinkowski RP, Brinkley BR, Earnshaw WC, et al. CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase. EMBO J 1991; 10:1245-54.
-
(1991)
EMBO J
, vol.10
, pp. 1245-1254
-
-
Yen, T.J.1
Compton, D.A.2
Wise, D.3
Zinkowski, R.P.4
Brinkley, B.R.5
Earnshaw, W.C.6
-
2
-
-
0036744787
-
Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E
-
Putkey FR, Cramer T, Morphew MK, Silk AD, Johnson RS, McIntosh JR, et al. Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E. Dev Cell 2002; 3:351-65.
-
(2002)
Dev Cell
, vol.3
, pp. 351-365
-
-
Putkey, F.R.1
Cramer, T.2
Morphew, M.K.3
Silk, A.D.4
Johnson, R.S.5
McIntosh, J.R.6
-
3
-
-
0001665802
-
CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint
-
Yao X, Abrieu A, Zheng Y, Sullivan KF, Cleveland DW. CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint. Nat Cell Biol 2000; 2:484-91.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 484-491
-
-
Yao, X.1
Abrieu, A.2
Zheng, Y.3
Sullivan, K.F.4
Cleveland, D.W.5
-
4
-
-
0032487444
-
Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1
-
Chan GK, Schaar BT, Yen TJ. Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1. J Cell Biol 1998; 143:49-63.
-
(1998)
J Cell Biol
, vol.143
, pp. 49-63
-
-
Chan, G.K.1
Schaar, B.T.2
Yen, T.J.3
-
5
-
-
0038446875
-
Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1
-
Mao Y, Abrieu A, Cleveland DW. Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1. Cell 2003; 114:87-98.
-
(2003)
Cell
, vol.114
, pp. 87-98
-
-
Mao, Y.1
Abrieu, A.2
Cleveland, D.W.3
-
6
-
-
0042978646
-
Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss
-
Weaver BA, Bonday ZQ, Putkey FR, Kops GJ, Silk AD, Cleveland DW. Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss. J Cell Biol 2003; 162:551-63.
-
(2003)
J Cell Biol
, vol.162
, pp. 551-563
-
-
Weaver, B.A.1
Bonday, Z.Q.2
Putkey, F.R.3
Kops, G.J.4
Silk, A.D.5
Cleveland, D.W.6
-
7
-
-
0026767624
-
CENP-E is a putative kinetochore motor that accumulates just before mitosis
-
Yen TJ, Li G, Schaar BT, Szilak I, Cleveland DW. CENP-E is a putative kinetochore motor that accumulates just before mitosis. Nature 1992; 359:536-9.
-
(1992)
Nature
, vol.359
, pp. 536-539
-
-
Yen, T.J.1
Li, G.2
Schaar, B.T.3
Szilak, I.4
Cleveland, D.W.5
-
8
-
-
0027940017
-
Mitotic regulation of microtubule cross-linking activity of CENP-E kinetochore protein
-
Liao H, Li G, Yen TJ. Mitotic regulation of microtubule cross-linking activity of CENP-E kinetochore protein. Science 1994; 265:394-8.
-
(1994)
Science
, vol.265
, pp. 394-398
-
-
Liao, H.1
Li, G.2
Yen, T.J.3
-
9
-
-
3343013148
-
Gene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delay
-
Tanudji M, Shoemaker J, L'Italien L, Russell L, Chin G, Schebye XM. Gene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delay. Mol Biol Cell 2004; 15:3771-81.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 3771-3781
-
-
Tanudji, M.1
Shoemaker, J.2
L'Italien, L.3
Russell, L.4
Chin, G.5
Schebye, X.M.6
-
10
-
-
33846065784
-
Aneuploidy acts both oncogenically and as a tumor suppressor
-
Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW. Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell 2007; 11:25-36.
-
(2007)
Cancer Cell
, vol.11
, pp. 25-36
-
-
Weaver, B.A.1
Silk, A.D.2
Montagna, C.3
Verdier-Pinard, P.4
Cleveland, D.W.5
-
11
-
-
0018387446
-
Promotion of microtubule assembly in vitro by taxol
-
Schiff PB, Fant J, Horwitz SB. Promotion of microtubule assembly in vitro by taxol. Nature 1979; 277:665-7.
-
(1979)
Nature
, vol.277
, pp. 665-667
-
-
Schiff, P.B.1
Fant, J.2
Horwitz, S.B.3
-
12
-
-
0000297058
-
Taxol stabilizes microtubules in mouse fibroblast cells
-
Schiff PB, Horwitz SB. Taxol stabilizes microtubules in mouse fibroblast cells. Proc Natl Acad Sci USA 1980; 77:1561-5.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 1561-1565
-
-
Schiff, P.B.1
Horwitz, S.B.2
-
13
-
-
0032933622
-
Taxol suppresses dynamics of individual microtubules in living human tumor cells
-
Yvon AM, Wadsworth P, Jordan MA. Taxol suppresses dynamics of individual microtubules in living human tumor cells. Mol Biol Cell 1999; 10:947-59.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 947-959
-
-
Yvon, A.M.1
Wadsworth, P.2
Jordan, M.A.3
-
14
-
-
0345275866
-
Gene expression and mitotic exit induced by microtubule-stabilizing drugs
-
Chen JG, Yang CP, Cammer M, Horwitz SB. Gene expression and mitotic exit induced by microtubule-stabilizing drugs. Cancer Res 2003; 63:7891-9.
-
(2003)
Cancer Res
, vol.63
, pp. 7891-7899
-
-
Chen, J.G.1
Yang, C.P.2
Cammer, M.3
Horwitz, S.B.4
-
15
-
-
26444449908
-
Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy
-
Ikui AE, Yang CP, Matsumoto T, Horwitz SB. Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy. Cell Cycle 2005; 4:1385-8.
-
(2005)
Cell Cycle
, vol.4
, pp. 1385-1388
-
-
Ikui, A.E.1
Yang, C.P.2
Matsumoto, T.3
Horwitz, S.B.4
-
16
-
-
0029049468
-
Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action
-
Bollag DM, McQueney PA, Zhu J, Hensens O, Koupal L, Liesch J, et al. Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action. Cancer Res 1995; 55:2325-33.
-
(1995)
Cancer Res
, vol.55
, pp. 2325-2333
-
-
Bollag, D.M.1
McQueney, P.A.2
Zhu, J.3
Hensens, O.4
Koupal, L.5
Liesch, J.6
-
17
-
-
0031027531
-
Activities of the microtubule-stabilizing agents epothilones a and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R))
-
Kowalski RJ, Giannakakou P, Hamel E. Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)). J Biol Chem 1997; 272:2534-41.
-
(1997)
J Biol Chem
, vol.272
, pp. 2534-2541
-
-
Kowalski, R.J.1
Giannakakou, P.2
Hamel, E.3
-
18
-
-
36048979369
-
Ixabepilone, first in a new class of antineoplastic agents: The natural epothilones and their analogues
-
Fornier MN. Ixabepilone, first in a new class of antineoplastic agents: the natural epothilones and their analogues. Clin Breast Cancer 2007; 7:757-63.
-
(2007)
Clin Breast Cancer
, vol.7
, pp. 757-763
-
-
Fornier, M.N.1
-
19
-
-
56049127901
-
Ixabepilone: A novel microtubule-stabilizing agent for the treatment of metastatic breast cancer
-
Goodin S. Ixabepilone: a novel microtubule-stabilizing agent for the treatment of metastatic breast cancer. Am J Health Syst Pharm 2008; 65:2017-26.
-
(2008)
Am J Health Syst Pharm
, vol.65
, pp. 2017-2026
-
-
Goodin, S.1
-
21
-
-
33749370142
-
A photoaffinity analogue of disco-dermolide specifically labels a peptide in beta-tubulin
-
Xia S, Kenesky CS, Rucker PV, Smith AB, 3rd, Orr GA, Horwitz SB. A photoaffinity analogue of disco-dermolide specifically labels a peptide in beta-tubulin. Biochemistry 2006; 45:11762-75.
-
(2006)
Biochemistry
, vol.45
, pp. 11762-11775
-
-
Xia, S.1
Kenesky, C.S.2
Rucker, P.V.3
Smith III, A.B.4
Orr, G.A.5
Horwitz, S.B.6
-
22
-
-
0032883001
-
Molecular effects of paclitaxel: Myths and reality
-
a critical review
-
Blagosklonny MV, Fojo T. Molecular effects of paclitaxel: myths and reality (a critical review). Int J Cancer 1999; 83:151-6.
-
(1999)
Int J Cancer
, vol.83
, pp. 151-156
-
-
Blagosklonny, M.V.1
Fojo, T.2
-
24
-
-
0037444386
-
Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an α-tubulin mutation
-
Martello LA, Verdier-Pinard P, Shen HJ, He L, Torres K, Orr GA, et al. Elevated levels of microtubule destabilizing factors in a Taxol-resistant/ dependent A549 cell line with an alpha-tubulin mutation. Cancer Res 2003; 63:1207-13. (Pubitemid 36355832)
-
(2003)
Cancer Research
, vol.63
, Issue.6
, pp. 1207-1213
-
-
Martello, L.A.1
Verdier-Pinard, P.2
Shen, H.-J.3
He, L.4
Torres, K.5
Orr, G.A.6
Horwitz, S.B.7
-
25
-
-
1942474378
-
Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint
-
Sudo T, Nitta M, Saya H, Ueno NT. Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint. Cancer Res 2004; 64:2502-8.
-
(2004)
Cancer Res
, vol.64
, pp. 2502-2508
-
-
Sudo, T.1
Nitta, M.2
Saya, H.3
Ueno, N.T.4
-
26
-
-
0035523572
-
Mutations in beta-tubulin map to domains involved in regulation of microtubule stability in epothilone-resistant cell lines
-
He L, Yang CP, Horwitz SB. Mutations in beta-tubulin map to domains involved in regulation of microtubule stability in epothilone-resistant cell lines. Mol Cancer Ther 2001; 1:3-10.
-
(2001)
Mol Cancer Ther
, vol.1
, pp. 3-10
-
-
He, L.1
Yang, C.P.2
Horwitz, S.B.3
-
27
-
-
0034730625
-
Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules
-
Ashar HR, James L, Gray K, Carr D, Black S, Armstrong L, et al. Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules. J Biol Chem 2000; 275:30451-7.
-
(2000)
J Biol Chem
, vol.275
, pp. 30451-30457
-
-
Ashar, H.R.1
James, L.2
Gray, K.3
Carr, D.4
Black, S.5
Armstrong, L.6
-
28
-
-
34248170746
-
Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function
-
Schafer-Hales K, Iaconelli J, Snyder JP, Prussia A, Nettles JH, El-Naggar A, et al. Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function. Mol Cancer Ther 2007; 6:1317-28.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1317-1328
-
-
Schafer-Hales, K.1
Iaconelli, J.2
Snyder, J.P.3
Prussia, A.4
Nettles, J.H.5
El-Naggar, A.6
-
29
-
-
0035844878
-
Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3 and CENP-E independently of its kinase activity
-
Sharp-Baker H, Chen RH. Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3 and CENP-E, independently of its kinase activity. J Cell Biol 2001; 153:1239-50.
-
(2001)
J Cell Biol
, vol.153
, pp. 1239-1250
-
-
Sharp-Baker, H.1
Chen, R.H.2
-
30
-
-
15244346231
-
A mitotic septin scaffold required for Mammalian chromosome congression and segregation
-
Spiliotis ET, Kinoshita M, Nelson WJ. A mitotic septin scaffold required for Mammalian chromosome congression and segregation. Science 2005; 307:1781-5.
-
(2005)
Science
, vol.307
, pp. 1781-1785
-
-
Spiliotis, E.T.1
Kinoshita, M.2
Nelson, W.J.3
-
31
-
-
34547101028
-
Human NUF2 interacts with centromere-associated protein e and is essential for a stable spindle microtubule-kinetochore attachment
-
Liu D, Ding X, Du J, Cai X, Huang Y, Ward T, et al. Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment. J Biol Chem 2007; 282:21415-24.
-
(2007)
J Biol Chem
, vol.282
, pp. 21415-21424
-
-
Liu, D.1
Ding, X.2
Du, J.3
Cai, X.4
Huang, Y.5
Ward, T.6
-
32
-
-
49649114642
-
Septin 7 interacts with centromere-associated protein e and is required for its kinetochore localization
-
Zhu M, Wang F, Yan F, Yao PY, Du J, Gao X, et al. Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization. J Biol Chem 2008; 283:18916-25.
-
(2008)
J Biol Chem
, vol.283
, pp. 18916-18925
-
-
Zhu, M.1
Wang, F.2
Yan, F.3
Yao, P.Y.4
Du, J.5
Gao, X.6
-
33
-
-
40849115019
-
SUMO-2/3 modification and binding regulate the association of CENP-E with kinetochores and progression through mitosis
-
Zhang XD, Goeres J, Zhang H, Yen TJ, Porter AC, Matunis MJ. SUMO-2/3 modification and binding regulate the association of CENP-E with kinetochores and progression through mitosis. Mol Cell 2008; 29:729-41.
-
(2008)
Mol Cell
, vol.29
, pp. 729-741
-
-
Zhang, X.D.1
Goeres, J.2
Zhang, H.3
Yen, T.J.4
Porter, A.C.5
Matunis, M.J.6
-
34
-
-
77953503003
-
Kinesin-14 Family Proteins HSET/XCTK2 Control Spindle Length by Cross-Linking and Sliding Microtubules
-
Cai S, Weaver LN, Ems-McClung SC, Walczak CE. Kinesin-14 Family Proteins HSET/XCTK2 Control Spindle Length by Cross-Linking and Sliding Microtubules. Mol Biol Cell 2008.
-
(2008)
Mol Biol Cell
-
-
Cai, S.1
Weaver, L.N.2
Ems-McClung, S.C.3
Walczak, C.E.4
-
35
-
-
19644392512
-
Roles of polymerization dynamics, opposed motors and a tensile element in governing the length of Xenopus extract meiotic spindles
-
Mitchison TJ, Maddox P, Gaetz J, Groen A, Shirasu M, Desai A, et al. Roles of polymerization dynamics, opposed motors and a tensile element in governing the length of Xenopus extract meiotic spindles. Mol Biol Cell 2005; 16:3064-76.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 3064-3076
-
-
Mitchison, T.J.1
Maddox, P.2
Gaetz, J.3
Groen, A.4
Shirasu, M.5
Desai, A.6
-
36
-
-
34249655122
-
Nonredundant functions of Kinesin-13s during meiotic spindle assembly
-
Ohi R, Burbank K, Liu Q, Mitchison TJ. Nonredundant functions of Kinesin-13s during meiotic spindle assembly. Curr Biol 2007; 17:953-9.
-
(2007)
Curr Biol
, vol.17
, pp. 953-959
-
-
Ohi, R.1
Burbank, K.2
Liu, Q.3
Mitchison, T.J.4
-
37
-
-
35148832753
-
Wild-type class I beta-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a beta-tubulin mutation
-
Wiesen KM, Xia S, Yang CP, Horwitz SB. Wild-type class I beta-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a beta-tubulin mutation. Cancer Lett 2007; 257:227-35.
-
(2007)
Cancer Lett
, vol.257
, pp. 227-235
-
-
Wiesen, K.M.1
Xia, S.2
Yang, C.P.3
Horwitz, S.B.4
-
38
-
-
0034665140
-
Taxol mediates serine phosphorylation of the 66-kDa Shc isoform
-
Yang CP, Horwitz SB. Taxol mediates serine phosphorylation of the 66-kDa Shc isoform. Cancer Res 2000; 60:5171-8.
-
(2000)
Cancer Res
, vol.60
, pp. 5171-5178
-
-
Yang, C.P.1
Horwitz, S.B.2
-
39
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, Vistica D, et al. New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 1990; 82:1107-12.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
|