Masking of a cathepsin G cleavage site in vivo contributes to the proteolytic resistance of major histocompatibility complex class II molecules

Immunology

Volumn 130, Issue 3, 2010, Pages 436-446

  Burster, Timo ^a   MacMillan, Henriette ^b   Hou, Tieying ^b   Schilling, James ^b   Truong, Phi ^b   Boehm, Bernhard O ^a   Zou, Fang ^a   Lau, Kenneth ^b   Strohman, Michael ^b   Schaffert, Steven ^b   Busch, Robert ^c   Mellins, Elizabeth D ^b  

^a UNIVERSITY OF ULM   (Germany)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SIDNEY SUSSEX COLLEGE   (United Kingdom)

Author keywords

Antigen presentation; APC; Cathepsin G; MHC class II; Proteolysis

Indexed keywords

CATHEPSIN G; HLA DM ANTIGEN; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; RECOMBINANT ANTIGEN;

ALLELE; ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOBLAST; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; ENDOSOME; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; REGULATORY MECHANISM; STEREOSPECIFICITY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; B-LYMPHOCYTES; CATHEPSIN G; CATHEPSINS; CELL LINE; DENDRITIC CELLS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-D ANTIGENS; HLA-DR ANTIGENS; HLA-DR1 ANTIGEN; HLA-DR3 ANTIGEN; HUMANS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDES; POLYMORPHISM, GENETIC; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT;

EID: 77953504762     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2010.03247.x     Document Type: Article

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