Monoclonal Antibodies Specific for the Empty Conformation of HLA-DR1 Reveal Aspects of the Conformational Change Associated with Peptide Binding

Journal of Biological Chemistry

Volumn 279, Issue 16, 2004, Pages 16561-16570

  Carven, Gregory J ^a   Chitta, Sriram ^b   Hilgert, Ivan ^c   Rushe, Mia M ^a   Baggio, Rick F ^d   Palmer, Michelle ^d   Arenas, Jaime E ^d   Strominger, Jack L ^e,f   Horejsi, Vaclav ^c   Santambrogio, Laura ^g   Stern, Lawrence J ^b,h  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^d Applied Biosystems   (United States)

^e HARVARD UNIVERSITY   (United States)

^f DANA FARBER CANCER INSTITUTE   (United States)

^g ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^h Dept of Pathology ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CONFORMATIONS; HYDRODYNAMICS; IMMUNOLOGY; SPECTROSCOPIC ANALYSIS;

CONFORMATIONAL CHANGES; PEPTIDE BINDING;

BIOCHEMISTRY;

CD4 ANTIGEN; HLA DR1 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ANTIGENIC VARIATION; ARTICLE; BETA CHAIN; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; GENE MAPPING; MOUSE; NONHUMAN; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; EPITOPE MAPPING; EPITOPES; HLA-DR1 ANTIGEN; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION;

ANIMALIA;

EID: 11144356225     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M314315200     Document Type: Article

References (62)

1. Watts, C. (1997) Annu. Rev. Immunol. 15, 821-850
2. McFarland, B. J., and Beeson, C. (2002) Med. Res. Rev. 22, 168-203
3. Jardetzky, T. S., Brown, J. H., Gorga, J. C., Stern, L. J., Urban, R. G., Strominger, J. L., and Wiley, D. C. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 734-738
4. Stern, L. J., and Wiley, D. C. (1994) Structure 2, 245-251
5. Sato, A. K., Zarutskie, J. A., Rushe, M. M., Lomakin, A., Natarajan, S. K., Sadegh-Nasseri, S., Benedek, G. B., and Stern, L. J. (2000) J. Biol. Chem. 275, 2165-2173
6. Natarajan, S. K., Assadi, M., and Sadegh-Nasseri, S. (1999) J. Immunol. 162, 4030-4036
7. Natarajan, S. K., Stern, L. J., and Sadegh-Nasseri, S. (1999) J. Immunol. 162, 3463-3470
8. Zarutskie, J. A., Sato, A. K., Rushe, M. M., Chan, I. C., Lomakin, A., Benedek, G. B., and Stern, L. J. (1999) Biochemistry 38, 5878-5887
9. Mason, K., Denney, D. W., Jr., and McConnell, H. M. (1995) J. Immunol. 154, 5216-5227
10. Mason, K., and McConnell, H. M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 12463-12466
11. Sadegh-Nasseri, S., and McConnell, H. M. (1989) Nature 337, 274-276
12. Sadegh-Nasseri, S., Stern, L. J., Wiley, D. C., and Germain, R. N. (1994) Nature 370, 647-650
13. Beeson, C., and McConnell, H. M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8842-8845
14. Beeson, C., Rabinowitz, J., Tate, K., Gutgemann, I., Chien, Y. H., Jones, P. P., Davis, M. M., and McConnell, H. M. (1996) J. Exp. Med. 184, 777-782
15. Schmitt, L., Boniface, J. J., Davis, M. M., and McConnell, H. M. (1999) J. Mol. Biol. 286, 207-218
16. Sadegh-Nasseri, S., and Germain, R. N. (1991) Nature 353, 167-170
17. Jensen, P. E. (1990) J. Exp. Med. 171, 1779-1784
18. Dornmair, K., Rothenhausler, B., and McConnell, H. M. (1989) Cold Spring Harbor Symp. Quant. Biol. 54, 409-416
19. Rabinowitz, J. D., Vrljic, M., Kasson, P. M., Liang, M. N., Busch, R., Boniface, J. J., Davis, M. M., and McConnell, H. M. (1998) Immunity 9, 699-709
20. Denzin, L. K., and Cresswell, P. (1995) Cell 82, 155-165
21. Kropshofer, H., Vogt, A. B., Moldenhauer, G., Hammer, J., Blum, J. S., and Hammerling, G. J. (1996) EMBO J. 15, 6144-6154
22. Joshi, R. V., Zarutskie, J. A., and Stern, L. J. (2000) Biochemistry 39, 3751-3762
23. Goldberg, M. E. (1991) Trends Biochem. Sci. 16, 358-362
24. Fedorov, A. N., Friguet, B., Djavadi-Ohaniance, L., Alakhov, Y. B., and Goldberg, M. E. (1992) J. Mol. Biol. 228, 351-358
25. Frayser, M., Sato, A. K., Xu, L., and Stern, L. J. (1999) Protein Expression Purif. 15, 105-114
26. Li, Y., Li, H., Martin, R., and Mariuzza, R. A. (2000) J. Mol. Biol. 304, 177-188
27. Stern, L. J., Brown, J. H., Jardetzky, T. S., Gorga, J. C., Urban, R. G., Strominger, J. L., and Wiley, D. C. (1994) Nature 368, 215-221
28. Cameron, T. O., Norris, P. J., Patel, A., Moulon, C., Rosenberg, E. S., Mellins, E. D., Wedderburn, L. R., and Stern, L. J. (2002) J. Immunol. Methods 268, 51-69
29. Cochran, J. R., and Stern, L. J. (2000) Chem. Biol. 7, 683-696
30. Bouvier, M., and Wiley, D. C. (1994) Science 265, 398-402
31. Bouvier, M., and Wiley, D. C. (1998) Nat. Struct. Biol. 5, 377-384
32. Boniface, J. J., Lyons, D. S., Wettstein, D. A., Allbritton, N. L., and Davis, M. M. (1996) J. Exp. Med. 183, 119-126
33. Fahnestock, M. L., Tamir, I., Narhi, L., and Bjorkman, P. J. (1992) Science 258, 1658-1662
34. Runnels, H. A., Moore, J. C., and Jensen, P. E. (1996) J. Exp. Med. 183, 127-136
35. Zarutskie, J. A., Busch, R., Zavala-Ruiz, Z., Rushe, M., Mellins, E. D., and Stern, L. J. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 12450-12455
36. Gorga, J. C., Knudsen, P. J., Foran, J. A., Strominger, J. L., and Burakoff, S. J. (1986) Cell Immunol. 103, 160-173
37. Fu, X. T., and Karr, R. W. (1994) Hum. Immunol. 39, 253-260
38. Stratikos, E., Wiley, D. C., and Stern, L. J. (2004) J. Immunol. 172, 1109-1117
39. Robinson, J., Waller, M. J., Parham, P., de Groot, N., Bontrop, R., Kennedy, L. J., Stoehr, P., and Marsh, S. G. (2003) Nucleic Acids Res. 31, 311-314
40. Hansen, B. E., Andersson, E. C., Madsen, L. S., Engberg, J., Sondergaard, L., Svejgaard, A., and Fugger, L. (1998) Tissue Antigens 51, 119-128
41. Scheirle, A., Takacs, B., Kremer, L., Marin, F., and Sinigaglia, F. (1992) J. Immunol. 149, 1994-1999
42. Stockel, J., Meinl, E., Hahnel, C., Malotka, J., Seitz, R., Drexler, K., Wekerle, H., and Dornmair, K. (1994) J. Biol. Chem. 269, 29571-29578
43. Scott, C. A., Garcia, K. C., Carbone, F. R., Wilson, I. A., and Teyton, L. (1996) J. Exp. Med. 183, 2087-2095
44. Scott, C. A., Garcia, K. C., Stura, E. A., Peterson, P. A., Wilson, I. A., and Teyton, L. (1998) Protein Sci. 7, 413-418
45. Stratmann, T., Apostolopoulos, V., Mallet-Designe, V., Corper, A. L., Scott, C. A., Wilson, I. A., Kang, A. S., and Teyton, L. (2000) J. Immunol. 165, 3214-3225
46. Wu, S., Maslanka, K., and Gorski, J. (1997) J. Immunol. 158, 3221-3226
47. Santambrogio, L., Sato, A. K., Fischer, F. R., Dorf, M. E., and Stern, L. J. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 15050-15055
48. Romani, N., Reider, D., Heuer, M., Ebner, S., Kampgen, E., Eibl, B., Niederwieser, D., and Schuler, G. (1996) J. Immunol. Methods 196, 137-151
49. Geysen, H. M., Rodda, S. J., Mason, T. J., Tribbick, G., and Schoofs, P. G. (1987) J. Immunol. Methods 102, 259-274
50. Gampfer, J. M., Samstag, A., Waclavicek, M., Wolf, H. M., Eibl, M. M., and Gulle, H. (2002) Vaccine 20, 3675-3684
51. Maeda, H., Miyamoto, M., Kokeguchi, S., Kono, T., Nishimura, F., Takashiba, S., and Murayama, Y. (2000) FEMS Immunol. Med. Microbiol. 26, 219-224
52. Matsushita, K., Nisizawa, T., Nagaoka, S., Kawagoe, M., and Koga, T. (1994) Infect. Immun. 62, 4034-4042
53. Kabat, E. A. (1970) Ann. N. Y. Acad. Sci. 169, 43-54
54. MacCallum, R. M., Martin, A. C., and Thornton, J. M. (1996) J. Mol. Biol. 262, 732-745
55. LaPan, K. E., Klapper, D. G., and Frelinger, J. A. (1992) Hybridoma 11, 217-223
56. Bolin, D. R., Swain, A. L., Sarabu, R., Berthel, S. J., Gillespie, P., Huby, N. J., Makofske, R., Orzechowski, L., Perrotta, A., Toth, K., Cooper, J. P., Jiang, N., Falcioni, F., Campbell, R., Cox, D., Gaizband, D., Belunis, C. J., Vidovic, D., Ito, K., Crowther, R., Kammlott, U., Zhang, X., Palermo, R., Weber, D., Guenot, J., Nagy, Z., and Olson, G. L. (2000) J. Med. Chem. 43, 2135-2148
57. Brown, J. H., Jardetzky, T., Saper, M. A., Samraoui, B., Bjorkman, P. J., and Wiley, D. C. (1988) Nature 332, 845-850
58. Murthy, V. L., and Stern, L. J. (1997) Structure 5, 1385-1396
59. Schmitt, L., Kratz, J. R., Davis, M. M., and McConnell, H. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 6581-6586
60. Chou, C. L., and Sadegh-Nasseri, S. (2000) J. Exp. Med. 192, 1697-1706
61. Doebele, R. C., Busch, R., Scott, H. M., Pashine, A., and Mellins, E. D. (2000) Immunity 13, 517-527
62. Sadegh-Nasseri, S., and Germain, R. N. (1992) Immunol. Today 13, 43-46