Simultaneous determination of ginsenoside Rg1, Re, Rd, Rb1 and ophiopogonin D in rat plasma by liquid chromatography/electrospray ionization mass spectrometric method and its application to pharmacokinetic study of 'SHENMAI' injection

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 862, Issue 1-2, 2008, Pages 72-78

  Xia, Chunhua ^a,b   Wang, Guangji ^a   Sun, Jianguo ^a   Hao, Haiping ^a   Xiong, Yuqing ^b   Gu, Shenghua ^a   Shang, Lili ^a   Zheng, Chaonan ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANCHANG UNIVERSITY   (China)

Author keywords

'SHENMAI' injection; Ginsenoside Rg1; LC ESI MS; Ophiopogonin D; Pharmacokinetics; Rb1; Rd; Re

Indexed keywords

CHROMATOGRAPHIC SEPARATION; GINSENOSIDE RG1; OPHIOPOGONIN D; RAT PLASMA; SELECTED ION MONITORING (SIM);

LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; PHASE INTERFACES; RATS;

DRUG PRODUCTS;

GINSENOSIDE RB 1; GINSENOSIDE RD; GINSENOSIDE RE; GINSENOSIDE RG 1; GLYCOSIDE; OPHIOPOGONIN D; UNCLASSIFIED DRUG;

ARTICLE; DRUG BLOOD LEVEL; ELECTROSPRAY MASS SPECTROMETRY; ION MONITORING; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GINSENOSIDES; RATS; REPRODUCIBILITY OF RESULTS; SAPONINS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPIROSTANS;

RATTUS;

EID: 38649110457     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.11.020     Document Type: Article

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