Ras signaling requires dynamic properties of Ets1 for phosphorylation- enhanced binding to coactivator CBP

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 22, 2010, Pages 10026-10031

  Nelson, Mary L ^a   Kang, Hyun Seo ^b   Lee, Gregory M ^b   Blaszczak, Adam G ^a   Lau, Desmond K W ^b   McIntosh, Lawrence P ^b   Graves, Barbara J ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Ets2; MAP kinase; Protein structure dynamics; Protein protein interaction; Transcriptional regulation

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; RAS PROTEIN; SERINE; THREONINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS1; TRANSCRIPTION FACTOR TAZ1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ASSAY; CONTROLLED STUDY; IONIC STRENGTH; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; SURFACE PROPERTY; TITRIMETRY;

AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; CREB-BINDING PROTEIN; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTO-ONCOGENE PROTEIN C-ETS-1; RAS PROTEINS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; STATIC ELECTRICITY;

EID: 77953395033     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0915137107     Document Type: Article

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