메뉴 건너뛰기




Volumn 1, Issue 6, 2009, Pages 933-947

Potential for immunotherapy with heat-killed Mycobacterium vaccae in respiratory medicine

Author keywords

Bronchospasm; Immune modulation; Immunotherapy; Lung cancer; Mycobacterium vaccae; Respiratory disease; Tuberculosis

Indexed keywords

ETHAMBUTOL; IMMUNOMODULATING AGENT; ISONIAZID; PLACEBO; PYRAZINAMIDE; RIFAMPICIN;

EID: 77953386628     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/imt.09.62     Document Type: Article
Times cited : (8)

References (82)
  • 1
    • 0025247068 scopus 로고
    • Improved immunotherapy for pulmonary tuberculosis with Mycobacterium vaccae
    • Compares different preparations of Mycobacterium vaccae in relation to their ability to induce immunological changes of apparent benefit in the treatment of tuberculosis
    • Bahr GM, Shaaban MA, Gabriel M et al.: Improved immunotherapy for pulmonary tuberculosis with Mycobacterium vaccae. Tubercle 71, 259-266 (1990). •• Compares different preparations of Mycobacterium vaccae in relation to their ability to induce immunological changes of apparent benefit in the treatment of tuberculosis.
    • (1990) Tubercle , vol.71 , pp. 259-266
    • Bahr, G.M.1    Shaaban, M.A.2    Gabriel, M.3
  • 2
    • 0031055962 scopus 로고    scopus 로고
    • Immunotherapy with Mycobacterium vaccae. 1. In the treatment of newly diagnosed pulmonary tuberculosis in Romania
    • Corlan E, Marica C, Macavei C, Stanford JL, Stanford CA: Immunotherapy with Mycobacterium vaccae. 1. In the treatment of newly diagnosed pulmonary tuberculosis in Romania. Respir. Med. 91, 13-19 (1997).
    • (1997) Respir. Med. , vol.91 , pp. 13-19
    • Corlan, E.1    Marica, C.2    Macavei, C.3    Stanford, J.L.4    Stanford, C.A.5
  • 3
    • 0031047709 scopus 로고    scopus 로고
    • Immunotherapy with Mycobacterium vaccae. 2. In the treatment of chronic or relapsed tuberculosis in Romania
    • Corlan E, Marica C, Macavei C, Stanford JL, Stanford CA: Immunotherapy with Mycobacterium vaccae. 2. In the treatment of chronic or relapsed tuberculosis in Romania. Respir. Med. 91, 21-29 (1997).
    • (1997) Respir. Med. , vol.91 , pp. 21-29
    • Corlan, E.1    Marica, C.2    Macavei, C.3    Stanford, J.L.4    Stanford, C.A.5
  • 4
    • 0028926570 scopus 로고
    • Immunotherapy for tuberculosis in African conditions
    • First evidence that immunotherapy for tuberculosis with M. vaccae can work in HIV-infected patients and suggests that there could be a beneficial effect on HIV itself
    • Onyebujoh P, Abdulmumini T, Robinson S, Rook GAW, Stanford JL: Immunotherapy for tuberculosis in African conditions. Respir. Med. 89, 199-207 (1995). • First evidence that immunotherapy for tuberculosis with M. vaccae can work in HIV-infected patients and suggests that there could be a beneficial effect on HIV itself.
    • (1995) Respir. Med. , vol.89 , pp. 199-207
    • Onyebujoh, P.1    Abdulmumini, T.2    Robinson, S.3    Rook, G.A.W.4    Stanford, J.L.5
  • 6
    • 0034066912 scopus 로고    scopus 로고
    • Randomized controlled trial of Mycobacterium vaccae immunotherapy in non-human immunodeficiency virus-infected Ugandan adults with newly diagnosed pulmonary tuberculosis
    • The Uganda-Case Western Reserve University Research Collaboration
    • Johnson JL, Kamya RM, Okwera A et al.: Randomized controlled trial of Mycobacterium vaccae immunotherapy in non-human immunodeficiency virus-infected Ugandan adults with newly diagnosed pulmonary tuberculosis. The Uganda-Case Western Reserve University Research Collaboration. J. Infect. Dis. 181, 1304-1312 (2000).
    • (2000) J. Infect. Dis. , vol.181 , pp. 1304-1312
    • Johnson, J.L.1    Kamya, R.M.2    Okwera, A.3
  • 7
    • 33646030263 scopus 로고    scopus 로고
    • Immunological consequences of three doses of heat-killed Mycobacterium vaccae in the immunotherapy of tuberculosis
    • Detailed, though small, study of three doses of M. vaccae against pulmonary tuberculosis. Clinical, haematological, radiological and immunological improvement are all recorded. It was from this study that the stored material for the current paper was obtained
    • Dlugovitzky D, Fiorenza G, Farroni M, Bogue C, Stanford C, Stanford J: Immunological consequences of three doses of heat-killed Mycobacterium vaccae in the immunotherapy of tuberculosis. Respir. Med. 100, 1079-1087 (2006). •• Detailed, though small, study of three doses of M. vaccae against pulmonary tuberculosis. Clinical, haematological, radiological and immunological improvement are all recorded. It was from this study that the stored material for the current paper was obtained.
    • (2006) Respir. Med. , vol.100 , pp. 1079-1087
    • Dlugovitzky, D.1    Fiorenza, G.2    Farroni, M.3    Bogue, C.4    Stanford, C.5    Stanford, J.6
  • 8
    • 3042802064 scopus 로고    scopus 로고
    • Evaluation of adjunct immunotherapy with killed Mycobacterium vaccae in the treatment of multibacillary leprosy and erythema nodosum leprosum
    • Casal M (Ed.), Barcelona, Prous Science Publishers, Barcelona, Spain
    • Ramu G, Grange J, Stanford J: Evaluation of adjunct immunotherapy with killed Mycobacterium vaccae in the treatment of multibacillary leprosy and erythema nodosum leprosum. In: Clinical Mycobacteriology. Casal M (Ed.), Barcelona, Prous Science Publishers, Barcelona, Spain 393-402 (1998).
    • (1998) Clinical Mycobacteriology , pp. 393-402
    • Ramu, G.1    Grange, J.2    Stanford, J.3
  • 9
    • 12244290348 scopus 로고    scopus 로고
    • The effects of Mycobacterium vaccae on allergen-induced airway responses in atopic asthma
    • Camporota L, Corkhill A, Long H et al.: The effects of Mycobacterium vaccae on allergen-induced airway responses in atopic asthma. Eur. Respir. J. 21, 287-293 (2003).
    • (2003) Eur. Respir. J. , vol.21 , pp. 287-293
    • Camporota, L.1    Corkhill, A.2    Long, H.3
  • 10
    • 33750245788 scopus 로고    scopus 로고
    • Mycobacterial immunization in grass pollen asthma and rhinitis
    • Hopkin JM, Ferry B, Coull P et al.: Mycobacterial immunization in grass pollen asthma and rhinitis. Thorax 53, 63 (1998).
    • (1998) Thorax , vol.53 , pp. 63
    • Hopkin, J.M.1    Ferry, B.2    Coull, P.3
  • 11
    • 0035094643 scopus 로고    scopus 로고
    • Intradermal administration of a killed Mycobacterium vaccae suspension (SRL 172) is associated with improvement in atopic dermatitis in children with moderate-to-severe disease
    • Arkwright PD, David TJ: Intradermal administration of a killed Mycobacterium vaccae suspension (SRL 172) is associated with improvement in atopic dermatitis in children with moderate-to-severe disease. J. Allergy Clin. Immunol. 107, 531-534 (2001).
    • (2001) J. Allergy Clin. Immunol. , vol.107 , pp. 531-534
    • Arkwright, P.D.1    David, T.J.2
  • 12
    • 0031836413 scopus 로고    scopus 로고
    • Immunotherapy with Mycobacterium vaccae in the treatment of psoriasis
    • Lehrer A, Bressanelli A, Wachsmann V et al.: Immunotherapy with Mycobacterium vaccae in the treatment of psoriasis. FEMS Immunol. Med. Microbiol. 21, 71-77 (1998).
    • (1998) FEMS Immunol. Med. Microbiol. , vol.21 , pp. 71-77
    • Lehrer, A.1    Bressanelli, A.2    Wachsmann, V.3
  • 13
    • 38149032470 scopus 로고    scopus 로고
    • Successful immunotherapy with Mycobacterium vaccae in the treatment of adenocarcinoma of the lung
    • Important paper describing how several doses of M. vaccae can significantly lengthen survival in patients with advanced adenocarcinoma of the lung, while having no such effect in patients with squamous carcinoma of the lung
    • Stanford JL, Stanford CA, O'Brien M, Grange JM: Successful immunotherapy with Mycobacterium vaccae in the treatment of adenocarcinoma of the lung. Eur. J. Cancer 44, 224-227 (2008). •• Important paper describing how several doses of M. vaccae can significantly lengthen survival in patients with advanced adenocarcinoma of the lung, while having no such effect in patients with squamous carcinoma of the lung.
    • (2008) Eur. J. Cancer , vol.44 , pp. 224-227
    • Stanford, J.L.1    Stanford, C.A.2    O'Brien, M.3    Grange, J.M.4
  • 14
    • 33748431182 scopus 로고    scopus 로고
    • Killed Mycobacterium vaccae suspension in children with moderate-to-severe atopic dermatitis: A randomized, double-blind, placebo-controlled trial
    • Berth-Jones J, Arkwright PD, Marasovic D, et al.: Killed Mycobacterium vaccae suspension in children with moderate-to-severe atopic dermatitis: a randomized, double-blind, placebo-controlled trial. Clin. Exp. Allergy. 36(9), 1115-1121 (2006).
    • (2006) Clin. Exp. Allergy , vol.36 , Issue.9 , pp. 1115-1121
    • Berth-Jones, J.1    Arkwright, P.D.2    Marasovic, D.3
  • 15
    • 33646564045 scopus 로고    scopus 로고
    • An open study to assess the efficacy clinically and immunologically of M. vaccae vaccine in patients with atopic dermatitis
    • Davies MG, Symons C, Shaw S, Kaminski ER: An open study to assess the efficacy clinically and immunologically of M. vaccae vaccine in patients with atopic dermatitis. J. Dermatolog. Treat. 17(2), 74-77 (2006).
    • (2006) J. Dermatolog. Treat. , vol.17 , Issue.2 , pp. 74-77
    • Davies, M.G.1    Symons, C.2    Shaw, S.3    Kaminski, E.R.4
  • 16
    • 0035224066 scopus 로고    scopus 로고
    • Environmental echoes
    • Explains how relationships with environmental mycobacteria change with time and the potential influence this could have on the prevalence of disease and the efficacy of bacterial immunotherapeutics
    • Stanford JL, Stanford CA, Grange JM: Environmental echoes. Sci. Prog. 84, 105-124 (2001). •• Explains how relationships with environmental mycobacteria change with time and the potential influence this could have on the prevalence of disease and the efficacy of bacterial immunotherapeutics.
    • (2001) Sci. Prog. , vol.84 , pp. 105-124
    • Stanford, J.L.1    Stanford, C.A.2    Grange, J.M.3
  • 17
    • 0033542849 scopus 로고    scopus 로고
    • Immunotherapy with Mycobacterium vaccae in patients with newly diagnosed pulmonary tuberculosis: A randomised controlled trial
    • Durban Immunotherapy Trial Group
    • Durban Immunotherapy Trial Group: Immunotherapy with Mycobacterium vaccae in patients with newly diagnosed pulmonary tuberculosis: a randomised controlled trial. Lancet 354, 116-119 (1999).
    • (1999) Lancet , vol.354 , pp. 116-119
  • 18
    • 0037264496 scopus 로고    scopus 로고
    • Mycobacterium vaccae immunotherapy for treating tuberculosis
    • CD001166
    • de Bruyn G, Garner P: Mycobacterium vaccae immunotherapy for treating tuberculosis. Cochrane Database Syst. Rev. CD001166 (2003).
    • (2003) Cochrane Database Syst. Rev.
    • De Bruyn, G.1    Garner, P.2
  • 19
    • 0037027056 scopus 로고    scopus 로고
    • Mycobacterium vaccae (SRL172) immunotherapy as an adjunct to standard antituberculosis treatment in HIV-infected adults with pulmonary tuberculosis: A randomised placebo-controlled trial
    • Mwinga A, Nunn A, Ngwira B et al.: Mycobacterium vaccae (SRL172) immunotherapy as an adjunct to standard antituberculosis treatment in HIV-infected adults with pulmonary tuberculosis: a randomised placebo-controlled trial. Lancet 360, 1050-1055 (2002).
    • (2002) Lancet , vol.360 , pp. 1050-1055
    • Mwinga, A.1    Nunn, A.2    Ngwira, B.3
  • 20
    • 0030760776 scopus 로고    scopus 로고
    • Pathogenesis of tuberculosis exposed to low and high doses of an environmental mycobacterial saprophyte before infection
    • Hernandez-Pando R, Pavon L, Arriaga K, Orozco H, Madrid-Marina V, Rook G: Pathogenesis of tuberculosis exposed to low and high doses of an environmental mycobacterial saprophyte before infection. Infect. Immun. 65(8), 3317-3327 (1997).
    • (1997) Infect. Immun. , vol.65 , Issue.8 , pp. 3317-3327
    • Hernandez-Pando, R.1    Pavon, L.2    Arriaga, K.3    Orozco, H.4    Madrid-Marina, V.5    Rook, G.6
  • 21
    • 0036278230 scopus 로고    scopus 로고
    • Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells
    • Zuany-Amorim C, Sawicka E, Manlius C et al.: Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells. Nat. Med. 8, 625-629 (2002).
    • (2002) Nat. Med. , vol.8 , pp. 625-629
    • Zuany-Amorim, C.1    Sawicka, E.2    Manlius, C.3
  • 22
    • 43049124077 scopus 로고    scopus 로고
    • Role of Mycobacterium vaccae in the protection induced by first generation Leishmania vaccine against murine model of leishmaniasis
    • Valian HK, Kenedy LKA, Rostami MN, Mohammadi AM, Khamesipour A: Role of Mycobacterium vaccae in the protection induced by first generation Leishmania vaccine against murine model of leishmaniasis. Parasitol. Res. 103, 21-28 (2008).
    • (2008) Parasitol. Res. , vol.103 , pp. 21-28
    • Valian, H.K.1    Kenedy, L.K.A.2    Rostami, M.N.3    Mohammadi, A.M.4    Khamesipour, A.5
  • 23
    • 0031732867 scopus 로고    scopus 로고
    • Mycobacterium vaccae (SRL172): A potential immunological adjuvant evaluated in rat prostate cancer
    • Hrouda D, Souberbielle BE, Kayaga J, Corbishley CM, Kirby RS, Dalgleish G: Mycobacterium vaccae (SRL172): a potential immunological adjuvant evaluated in rat prostate cancer. Br. J. Urol. 82(6), 870-876 (1998).
    • (1998) Br. J. Urol. , vol.82 , Issue.6 , pp. 870-876
    • Hrouda, D.1    Souberbielle, B.E.2    Kayaga, J.3    Corbishley, C.M.4    Kirby, R.S.5    Dalgleish, G.6
  • 24
    • 34047137281 scopus 로고    scopus 로고
    • Improved outcome of Trypanosoma cruzi infection in rats following treatment in early life with suspensions of heat-killed environmental Actinomycetales
    • DOI 10.1016/j.vaccine.2006.11.062, PII S0264410X06013028
    • Fontanella GH, Pascutti MF, Daurelio L et al.: Improved outcome of Trypanosoma cruzi infection in rats following treatment in early life with suspensions of heat-killed environmental Actinomycetales. Vaccine 25, 3492-3500 (2007). (Pubitemid 46527982)
    • (2007) Vaccine , vol.25 , Issue.17 , pp. 3492-3500
    • Fontanella, G.H.1    Pascutti, M.F.2    Daurelio, L.3    Perez, A.R.4    Nocito, A.L.5    Wojdyla, D.6    Bottasso, O.7    Revelli, S.S.8    Stanford, J.L.9
  • 25
    • 0035240289 scopus 로고    scopus 로고
    • The immunotherapeutic effect of Mycobacterium vaccae vaccine on initially treated pulmonary tuberculosis
    • Luo Y: The immunotherapeutic effect of Mycobacterium vaccae vaccine on initially treated pulmonary tuberculosis. Chin. J. Evid. Based Med. 24, 43-47 (2001).
    • (2001) Chin. J. Evid. Based Med. , vol.24 , pp. 43-47
    • Luo, Y.1
  • 26
    • 0034142781 scopus 로고    scopus 로고
    • Immunotherapeutic effect of Mycobacterium vaccae on multi-drug resistant pulmonary tuberculosis
    • Luo YA, Lu SH, Guo SL et al.: Immunotherapeutic effect of Mycobacterium vaccae on multi-drug resistant pulmonary tuberculosis. Chin. J. Tuberc. Resp. Dis. 23(2), 85-88 (2000).
    • (2000) Chin. J. Tuberc. Resp. Dis. , vol.23 , Issue.2 , pp. 85-88
    • Luo, Y.A.1    Lu, S.H.2    Guo, S.L.3
  • 27
    • 34347377411 scopus 로고    scopus 로고
    • Adjuvant effect of Mycobacterium vaccae on treatment of recurrent treated pulmonary tuberculosis: A meta-analysis
    • Fan MY, Chen XR, Wang K et al.: Adjuvant effect of Mycobacterium vaccae on treatment of recurrent treated pulmonary tuberculosis: a meta-analysis. Chin. J. Evid. based Med. 7(6), 449-455 (2007).
    • (2007) Chin. J. Evid. Based Med. , vol.7 , Issue.6 , pp. 449-455
    • Fan, M.Y.1    Chen, X.R.2    Wang, K.3
  • 28
    • 65549169610 scopus 로고    scopus 로고
    • Immunotherapeutical potential of Mycobacterium vaccae on M. tuberculosis infection in mice
    • Lijun X, Yanyan W, Xiaodong Z, Xiangdong G, Lifeng T, Haimimg W: Immunotherapeutical potential of Mycobacterium vaccae on M. tuberculosis infection in mice. Cell. Molec. Immunol. 6(1), 67-72 (2009).
    • (2009) Cell. Molec. Immunol. , vol.6 , Issue.1 , pp. 67-72
    • Lijun, X.1    Yanyan, W.2    Xiaodong, Z.3    Xiangdong, G.4    Lifeng, T.5    Haimimg, W.6
  • 29
    • 28744447221 scopus 로고    scopus 로고
    • Effects of M. vaccae on airway contraction and inflammation in asthmatic guinea pigs
    • Zhao XY, Xie QM, Chen JQ, Bian RL: [Effects of M. vaccae on airway contraction and inflammation in asthmatic guinea pigs] Zhonghua Jie He He Hu Xi Za Zhi 26(4), 218-222 (2003).
    • (2003) Zhonghua Jie He He Hu Xi Za Zhi , vol.26 , Issue.4 , pp. 218-222
    • Zhao, X.Y.1    Xie, Q.M.2    Chen, J.Q.3    Bian, R.L.4
  • 30
    • 0033213894 scopus 로고    scopus 로고
    • Pulmonary epithelial cells are a source of IL-8 in the response to Mycobacterium tuberculosis: Essential role of IL-1 from infected monocytes in a NF-κB dependent network
    • Wickremasinghe MI, Thomas LH, Friedland JS: Pulmonary epithelial cells are a source of IL-8 in the response to Mycobacterium tuberculosis: essential role of IL-1 from infected monocytes in a NF-κB dependent network. J. Immunol. 163, 3936-3947 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 3936-3947
    • Wickremasinghe, M.I.1    Thomas, L.H.2    Friedland, J.S.3
  • 31
    • 0028890171 scopus 로고
    • Enhanced interleukin-8 release and gene expression in macrophages after exposure to Mycobacterium tuberculosis and its components
    • Zhang Y, Broser M, Cohen H et al.: Enhanced interleukin-8 release and gene expression in macrophages after exposure to Mycobacterium tuberculosis and its components. J. Clin. Invest. 95, 586-592 (1995).
    • (1995) J. Clin. Invest. , vol.95 , pp. 586-592
    • Zhang, Y.1    Broser, M.2    Cohen, H.3
  • 32
    • 0029050004 scopus 로고
    • Inhibition of ex vivo proinflammatory cytokine secretion in fatal Mycobacterium tuberculosis infection
    • Friedland JS, Hartley JC, Hartley CG, Shattock RJ, Griffin GE: Inhibition of ex vivo proinflammatory cytokine secretion in fatal Mycobacterium tuberculosis infection. Clin. Exp. Immunol. 100, 233-238 (1995).
    • (1995) Clin. Exp. Immunol. , vol.100 , pp. 233-238
    • Friedland, J.S.1    Hartley, J.C.2    Hartley, C.G.3    Shattock, R.J.4    Griffin, G.E.5
  • 33
    • 0032161567 scopus 로고    scopus 로고
    • Chemokines induced by infection of mononuclear phagocytes with mycobacteria and present in lung alveoli during active pulmonary tuberculosis
    • Sadek MI, Sada E, Toossi Z, Schwander SK, Rich EA: Chemokines induced by infection of mononuclear phagocytes with mycobacteria and present in lung alveoli during active pulmonary tuberculosis. Am. J. Respir. Cell. Mol. Biol. 19, 513-521 (1998).
    • (1998) Am. J. Respir. Cell. Mol. Biol. , vol.19 , pp. 513-521
    • Sadek, M.I.1    Sada, E.2    Toossi, Z.3    Schwander, S.K.4    Rich, E.A.5
  • 34
    • 0023706894 scopus 로고
    • Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
    • Ding AH, Nathan CF, Stuehr DJ: Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 141, 2407-2412 (1988).
    • (1988) J. Immunol. , vol.141 , pp. 2407-2412
    • Ding, A.H.1    Nathan, C.F.2    Stuehr, D.J.3
  • 35
    • 0028245493 scopus 로고
    • Growth inhibition of Mycobacterium bovis by IFN-γ stimulated macrophages: Regulation by endogenous tumor necrosis factor-α and by IL-10
    • Flesch IE, Hess JH, Oswald IP, Kaufmann SH: Growth inhibition of Mycobacterium bovis by IFN-γ stimulated macrophages: regulation by endogenous tumor necrosis factor-α and by IL-10. Int. Immunol. 6, 693-700 (1994).
    • (1994) Int. Immunol. , vol.6 , pp. 693-700
    • Flesch, I.E.1    Hess, J.H.2    Oswald, I.P.3    Kaufmann, S.H.4
  • 36
    • 0028979703 scopus 로고
    • Tumor necrosis factor α is required in the protective immune response against Mycobacterium tuberculosis in mice
    • Flynn J, Goldstein MM, Chan J et al.: Tumor necrosis factor α is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity 2, 561-572 (1995).
    • (1995) Immunity , vol.2 , pp. 561-572
    • Flynn, J.1    Goldstein, M.M.2    Chan, J.3
  • 37
    • 0041653315 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: A multicenter active-surveillance report
    • DOI 10.1002/art.11137
    • Gomez-Reino JJ, Carmona L, Valverde VR et al.: Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: a multicenter active-surveillance report. Arthritis Rheum. 48, 2122-2127 (2003). (Pubitemid 36959191)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.8 , pp. 2122-2127
    • Gomez-Reino, J.J.1    Carmona, L.2    Rodriguez Valverde, V.3    Mola, E.M.4    Montero, M.D.5
  • 38
    • 0023229507 scopus 로고
    • 3 metabolites and tumour necrosis factor in the pathogenesis of tuberculosis
    • Rook GAW, Taverne J, Leveton C et al.: The role of γ interferon, vitamin D3 metabolites and tumour necrosis factor in the pathogenesis of tuberculosis. Immunology 62, 229-234 (1987). (Pubitemid 17140031)
    • (1987) Immunology , vol.62 , Issue.2 , pp. 229-234
    • Rook, G.A.W.1    Taverne, J.2    Leveton, C.3    Steele, J.4
  • 39
    • 0034440521 scopus 로고    scopus 로고
    • Immunopathologic effects of tumor necrosis factor α in murine mycobacterial infection are dose dependent
    • Bekker LG, Moreira AL, Bergtold A et al.: Immunopathologic effects of tumor necrosis factor α in murine mycobacterial infection are dose dependent. Infect. Immun. 68, 6954-6961 (2000).
    • (2000) Infect. Immun. , vol.68 , pp. 6954-6961
    • Bekker, L.G.1    Moreira, A.L.2    Bergtold, A.3
  • 40
    • 0028168447 scopus 로고
    • The role of TNF-alpha in T-cell-mediated inflammation depends on the Th1/Th2 cytokine balance
    • Hernandez-Pando R, Rook GA: The role of TNF-α in T-cell-mediated inflammation depends on the Th1/Th2 cytokine balance. Immunology 82, 591-595 (1994). (Pubitemid 2119263)
    • (1994) Immunology , vol.82 , Issue.4 , pp. 591-595
    • Hernandez-Pando, R.1    Rook, G.A.W.2
  • 41
    • 1642473161 scopus 로고    scopus 로고
    • Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: Changes in the inflammatory effects of TNF-α and in the regulation of fibrosis
    • Hernandez-Pando R, Aguilar D, Hernandez ML, Orozco H, Rook G: Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-α and in the regulation of fibrosis. Eur. J. Immunol. 34, 174-183 (2004).
    • (2004) Eur. J. Immunol. , vol.34 , pp. 174-183
    • Hernandez-Pando, R.1    Aguilar, D.2    Hernandez, M.L.3    Orozco, H.4    Rook, G.5
  • 42
    • 0034113481 scopus 로고    scopus 로고
    • + T cells from patients with tuberculosis is related to the presence of pulmonary cavities
    • + T cells from patients with tuberculosis is related to the presence of pulmonary cavities. J. Infect. Dis. 181, 1194-1197 (2000).
    • (2000) J. Infect. Dis. , vol.181 , pp. 1194-1197
    • Van Crevel, R.1    Karyadi, E.2    Preyers, F.3
  • 43
    • 0037541415 scopus 로고    scopus 로고
    • T lymphocyte phenotypic profile in lung segments affected by cavitary and non-cavitary tuberculosis
    • Mazzarella G, Bianco A, Perna F et al.: T lymphocyte phenotypic profile in lung segments affected by cavitary and non-cavitary tuberculosis. Clin. Exp. Immunol. 132, 283-288 (2003).
    • (2003) Clin. Exp. Immunol. , vol.132 , pp. 283-288
    • Mazzarella, G.1    Bianco, A.2    Perna, F.3
  • 44
    • 0025335954 scopus 로고
    • In vitro production of tumour necrosis factor and prostaglandin E2 by peripheral blood mononuclear cells from tuberculosis patients
    • Cadranel J, Philippe C, Perez J et al.: In vitro production of tumour necrosis factor and prostaglandin E2 by peripheral blood mononuclear cells from tuberculosis patients. Clin. Exp. Immunol. 81, 319-324 (1990).
    • (1990) Clin. Exp. Immunol. , vol.81 , pp. 319-324
    • Cadranel, J.1    Philippe, C.2    Perez, J.3
  • 45
    • 0031947095 scopus 로고    scopus 로고
    • Local immune responses correlate with presentation and outcome in tuberculosis
    • Condos R, Rom WN, Liu YM, Schluger NW: Local immune responses correlate with presentation and outcome in tuberculosis. Am. J. Respir. Crit. Care Med. 157, 729-735 (1998).
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , pp. 729-735
    • Condos, R.1    Rom, W.N.2    Liu, Y.M.3    Schluger, N.W.4
  • 46
    • 0035154749 scopus 로고    scopus 로고
    • Circulating TNF-α, TGF-β, and IL-10 in tuberculosis patients and healthy contacts
    • Olobo JO, Geletu M, Demissie A et al.: Circulating TNF-α, TGF-β, and IL-10 in tuberculosis patients and healthy contacts. Scand. J. Immunol. 53, 85-91 (2001).
    • (2001) Scand. J. Immunol. , vol.53 , pp. 85-91
    • Olobo, J.O.1    Geletu, M.2    Demissie, A.3
  • 47
    • 15844380037 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis
    • Nicholson S, Bonecini-Almeida Mda G, Lapa e Silva JR et al.: Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis. J. Exp. Med. 183, 2293-2302 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 2293-2302
    • Nicholson, S.1    Bonecini-Almeida, Mda.G.2    Lapa E Silva, J.R.3
  • 48
    • 0033978631 scopus 로고    scopus 로고
    • Nitric oxide modulates interleukin-1β and tumor necrosis factor-α synthesis by alveolar macrophages in pulmonary tuberculosis
    • Kuo HP, Wang CH, Huang KS et al.: Nitric oxide modulates interleukin-1β and tumor necrosis factor-α synthesis by alveolar macrophages in pulmonary tuberculosis. Am. J. Respir. Crit. Care Med. 161, 192-199 (2000).
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 192-199
    • Kuo, H.P.1    Wang, C.H.2    Huang, K.S.3
  • 49
    • 0031745963 scopus 로고    scopus 로고
    • Increased exhaled nitric oxide in active pulmonary tuberculosis due to inducible NO synthase upregulation in alveolar macrophages
    • Wang CH, Liu CY, Lin HC, Yu CT, Chung KF, Kuo HP: Increased exhaled nitric oxide in active pulmonary tuberculosis due to inducible NO synthase upregulation in alveolar macrophages. Eur. Respir. J. 11, 809-815 (1998).
    • (1998) Eur. Respir. J. , vol.11 , pp. 809-815
    • Wang, C.H.1    Liu, C.Y.2    Lin, H.C.3    Yu, C.T.4    Chung, K.F.5    Kuo, H.P.6
  • 50
    • 0031400122 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis (MTB)-stimulated production of nitric oxide by human alveolar macrophages and relationship of nitric oxide production to growth inhibition of MTB
    • Rich EA, Torres M, Sada E, Finegan CK, Hamilton BD, Toossi Z: Mycobacterium tuberculosis (MTB)-stimulated production of nitric oxide by human alveolar macrophages and relationship of nitric oxide production to growth inhibition of MTB. Tuber. Lung Dis. 78, 247-255 (1997).
    • (1997) Tuber. Lung Dis. , vol.78 , pp. 247-255
    • Rich, E.A.1    Torres, M.2    Sada, E.3    Finegan, C.K.4    Hamilton, B.D.5    Toossi, Z.6
  • 51
    • 0032412102 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line
    • Rockett KA, Brookes R, Udalova I, Vidal V, Hill AV, Kwiatkowski D: 1,25-dihydroxyvitamin D3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line. Infect. Immunol. 66, 5314-5321 (1998).
    • (1998) Infect. Immunol. , Issue.66 , pp. 5314-5321
    • Rockett, K.A.1    Brookes, R.2    Udalova, I.3    Vidal, V.4    Hill, A.V.5    Kwiatkowski, D.6
  • 52
    • 0034535335 scopus 로고    scopus 로고
    • Influence of disease severity on nitrite and cytokine production by peripheral blood mononuclear cells from patients with pulmonary tuberculosis
    • Dlugovitzky D, Bay ML, Rateni L et al.: Influence of disease severity on nitrite and cytokine production by peripheral blood mononuclear cells from patients with pulmonary tuberculosis. Clin. Exp. Immunol. 122, 343-349 (2000).
    • (2000) Clin. Exp. Immunol. , vol.122 , pp. 343-349
    • Dlugovitzky, D.1    Bay, M.L.2    Rateni, L.3
  • 53
    • 0028894398 scopus 로고
    • The production of cytokines by polymorphonuclear neutrophils
    • Cassatella MA: The production of cytokines by polymorphonuclear neutrophils. Immunol. Today 16, 21 (1995).
    • (1995) Immunol. Today , vol.16 , pp. 21
    • Cassatella, M.A.1
  • 54
    • 33744920115 scopus 로고    scopus 로고
    • Production of interferon-γ by myeloid cells - Fact or fancy?
    • Bogdan C, Schleicher U: Production of interferon-γ by myeloid cells - fact or fancy? Trends Immunology 27, 282-290 (2006).
    • (2006) Trends Immunology , vol.27 , pp. 282-290
    • Bogdan, C.1    Schleicher, U.2
  • 55
  • 56
  • 57
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri G: Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3, 133-146 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 58
    • 0036219062 scopus 로고    scopus 로고
    • Genetic dissection of immunity to mycobacteria: The human model
    • Casanova JL, Abel L: Genetic dissection of immunity to mycobacteria: the human model. Annu. Rev. Immunol. 20, 581-620 (2002).
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 581-620
    • Casanova, J.L.1    Abel, L.2
  • 59
    • 0027944179 scopus 로고
    • Enhancement of intracellular growth of Mycobacterium tuberculosis in human monocytes by transforming growth factor-β1
    • Hirsch CS, Yoneda T, Averill L et al.: Enhancement of intracellular growth of Mycobacterium tuberculosis in human monocytes by transforming growth factor-β1. J. Infect. Dis. 170, 1229-1237 (1994).
    • (1994) J. Infect. Dis. , vol.170 , pp. 1229-1237
    • Hirsch, C.S.1    Yoneda, T.2    Averill, L.3
  • 60
    • 0029038092 scopus 로고
    • Selective deactivation of human monocyte functions by TGF-β
    • Warwick-Davies J, Lowrie DB, Cole PJ: Selective deactivation of human monocyte functions by TGF-β. J. Immunol. 155, 3186-3195 (1995).
    • (1995) J. Immunol. , vol.155 , pp. 3186-3195
    • Warwick-Davies, J.1    Lowrie, D.B.2    Cole, P.J.3
  • 61
    • 0032708776 scopus 로고    scopus 로고
    • Interaction of Mycobacterium tuberculosis-induced transforming growth factor-β1 and interleukin-10
    • Othieno C, Hirsch CS, Hamilton BD et al.: Interaction of Mycobacterium tuberculosis-induced transforming growth factor-β1 and interleukin-10. Infect. Immun. 67, 5730-5735 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 5730-5735
    • Othieno, C.1    Hirsch, C.S.2    Hamilton, B.D.3
  • 62
    • 0028984644 scopus 로고
    • Enhanced production of TGF-β by blood monocytes from patients with active tuberculosis and presence of TGF-β in tuberculous granulomatous lung lesions
    • Toossi Z, Gogate P, Shiratsuchi H et al.: Enhanced production of TGF-β by blood monocytes from patients with active tuberculosis and presence of TGF-β in tuberculous granulomatous lung lesions. J. Immunol. 154, 465-473 (1995).
    • (1995) J. Immunol. , vol.154 , pp. 465-473
    • Toossi, Z.1    Gogate, P.2    Shiratsuchi, H.3
  • 63
    • 0027980203 scopus 로고
    • Mechanism of suppression of nitric oxide synthase expression by interleukin-4 in primary mouse macrophages
    • Bogdan C, Vodovotz Y, Paik J, Xie QW, Nathan C: Mechanism of suppression of nitric oxide synthase expression by interleukin-4 in primary mouse macrophages. J. Leukoc. Biol. 55, 227-233 (1994).
    • (1994) J. Leukoc. Biol. , vol.55 , pp. 227-233
    • Bogdan, C.1    Vodovotz, Y.2    Paik, J.3    Xie, Q.W.4    Nathan, C.5
  • 65
    • 0141796312 scopus 로고    scopus 로고
    • TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
    • Belghith M, Bluestone JA, Barriot S, Megret J, Bach JF, Chatenoud L: TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat. Med. 9, 1202-1208 (2003).
    • (2003) Nat. Med. , vol.9 , pp. 1202-1208
    • Belghith, M.1    Bluestone, J.A.2    Barriot, S.3    Megret, J.4    Bach, J.F.5    Chatenoud, L.6
  • 66
    • 0742269689 scopus 로고    scopus 로고
    • TGF-β, T-cell tolerance and anti-CD3 therapy
    • Bommireddy R, Doetschman T: TGF-β, T-cell tolerance and anti-CD3 therapy. Trends Mol. Med. 10, 3-9 (2004).
    • (2004) Trends Mol. Med. , vol.10 , pp. 3-9
    • Bommireddy, R.1    Doetschman, T.2
  • 67
    • 34748873441 scopus 로고    scopus 로고
    • Regulatory T cells and infection: A dangerous necessity
    • Belkaid Y: Regulatory T cells and infection: a dangerous necessity. Nat. Rev. Immunol. 7, 875-888 (2007).
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 875-888
    • Belkaid, Y.1
  • 69
    • 38949133035 scopus 로고    scopus 로고
    • IL-23 and IL-17 in tuberculosis
    • Shabaana AK, Cooper AM: IL-23 and IL-17 in tuberculosis. Cytokine 41, 79-83 (2008).
    • (2008) Cytokine , vol.41 , pp. 79-83
    • Shabaana, A.K.1    Cooper, A.M.2
  • 70
    • 0033152737 scopus 로고    scopus 로고
    • Lung carcinoma: Analysis of T helper type 1 and 2 cells and T cytotoxic type 1 and 2 cells by intracellular cytokine detection with flow cytometry
    • Ito N, Nakamura H, Tanaka Y, Ohgi S: Lung carcinoma: analysis of T helper type 1 and 2 cells and T cytotoxic type 1 and 2 cells by intracellular cytokine detection with flow cytometry. Cancer 85(11), 2359-2367 (1999).
    • (1999) Cancer , vol.85 , Issue.11 , pp. 2359-2367
    • Ito, N.1    Nakamura, H.2    Tanaka, Y.3    Ohgi, S.4
  • 71
    • 0032822849 scopus 로고
    • Therapeutic vaccination for cancer, the potential value of mycobacterial products
    • Stanford JL. Stanford CA, Baban B, Grange JM: Therapeutic vaccination for cancer, the potential value of mycobacterial products. Int. J. Pharmaceut. Med. 12, 191-195 (1992).
    • (1992) Int. J. Pharmaceut. Med. , vol.12 , pp. 191-195
    • Stanford, J.L.1    Stanford, C.A.2    Baban, B.3    Grange, J.M.4
  • 72
    • 0032812103 scopus 로고    scopus 로고
    • Possible improved survival of patients with stage IV AJCC melanoma receiving SRL 172 immunotherapy: Correlation with induction of increased levels of intracellular interleukin-2 in peripheral blood leucocytes
    • Maraveyas A, Baban B, Kennard D et al.: Possible improved survival of patients with stage IV AJCC melanoma receiving SRL 172 immunotherapy: correlation with induction of increased levels of intracellular interleukin-2 in peripheral blood leucocytes. Ann. Oncol. 10, 817-824 (1999).
    • (1999) Ann. Oncol. , vol.10 , pp. 817-824
    • Maraveyas, A.1    Baban, B.2    Kennard, D.3
  • 73
    • 0036134656 scopus 로고    scopus 로고
    • Prevention of experimental myointimal hyperplasia by immunomodulation
    • Demonstrates that treatment with M. vaccae reduces the severity of carotid myointimal hyperplasia following experimental balloon angioplasty
    • Stansby G, Chan YC, Berwanger CS, Shurey S, Rook GA, Stanford JL: Prevention of experimental myointimal hyperplasia by immunomodulation. Eur. J. Vasc. Endovasc. Surg. 23, 23-28 (2002). • Demonstrates that treatment with M. vaccae reduces the severity of carotid myointimal hyperplasia following experimental balloon angioplasty.
    • (2002) Eur. J. Vasc. Endovasc. Surg. , vol.23 , pp. 23-28
    • Stansby, G.1    Chan, Y.C.2    Berwanger, C.S.3    Shurey, S.4    Rook, G.A.5    Stanford, J.L.6
  • 74
    • 65649109749 scopus 로고    scopus 로고
    • The common mycobacterial antigens and their importance in the treatment of disease
    • Discusses the part played by immune recognition of the common antigens of mycobacteria, including their heat-shock proteins, in many diseases and the importance of cross-reactive host proteins as targets for M. vaccae immunotherapy
    • Stanford J, Stanford C, Stansby G, Bottasso O, Bahr G, Grange J: The common mycobacterial antigens and their importance in the treatment of disease. Current Pharm. Des. 15, 1248-1260 (2009). •• Discusses the part played by immune recognition of the common antigens of mycobacteria, including their heat-shock proteins, in many diseases and the importance of cross-reactive host proteins as targets for M. vaccae immunotherapy.
    • (2009) Current Pharm. Des. , vol.15 , pp. 1248-1260
    • Stanford, J.1    Stanford, C.2    Stansby, G.3    Bottasso, O.4    Bahr, G.5    Grange, J.6
  • 75
    • 3442886281 scopus 로고    scopus 로고
    • SRL172 (killed Mycobacterium vaccae) in addition to standard chemotherapy improves quality of life, without affecting survival, in patients with advanced non-small-cell lung cancer: Phase III results
    • O'Brien ME, Anderson H, Kaukel E et al.: SRL172 (killed Mycobacterium vaccae) in addition to standard chemotherapy improves quality of life, without affecting survival, in patients with advanced non-small-cell lung cancer: Phase III results. Ann. Oncol. 15, 906-914 (2004).
    • (2004) Ann. Oncol. , vol.15 , pp. 906-914
    • O'Brien, M.E.1    Anderson, H.2    Kaukel, E.3
  • 76
    • 11444268632 scopus 로고    scopus 로고
    • Addition of SRL172 to standard chemotherapy in small-cell lung cancer (SCLC) improves symptom control
    • Harper-Wynne CL, Sumpter K, Ryan C et al.: Addition of SRL172 to standard chemotherapy in small-cell lung cancer (SCLC) improves symptom control. Lung Cancer 47, 289-290 (2005).
    • (2005) Lung Cancer , vol.47 , pp. 289-290
    • Harper-Wynne, C.L.1    Sumpter, K.2    Ryan, C.3
  • 77
    • 41149108949 scopus 로고    scopus 로고
    • The hygiene hypothesis and psychiatric disorders
    • Rook GAW, Lowry CA: The hygiene hypothesis and psychiatric disorders. Trends Immunology 29, 150-158 (2008).
    • (2008) Trends Immunology , vol.29 , pp. 150-158
    • Rook, G.A.W.1    Lowry, C.A.2
  • 78
    • 30644459622 scopus 로고    scopus 로고
    • Stress and depression-induced immune dysfunction: Implications for the development and progression of cancer
    • Reiche EM, Morimoto HK, Nunes SM: Stress and depression-induced immune dysfunction: implications for the development and progression of cancer. Int. Rev. Psychiatry 17, 515-527 (2005).
    • (2005) Int. Rev. Psychiatry , vol.17 , pp. 515-527
    • Reiche, E.M.1    Morimoto, H.K.2    Nunes, S.M.3
  • 79
    • 77953405151 scopus 로고    scopus 로고
    • Experimental immunotherapeutic approaches for athersclerosis
    • (Epub ahead of print)
    • Shahzada A, Binder CJ: Experimental immunotherapeutic approaches for athersclerosis. Clin. Immunol. (2009) (Epub ahead of print).
    • (2009) Clin. Immunol.
    • Shahzada, A.1    Binder, C.J.2
  • 80
    • 0036792154 scopus 로고    scopus 로고
    • A human endogenous retroviral sequence encoding an antigen recognised on melanoma by cytolytic T lymphocytes
    • Firmly associates a human endogenous retrovirus in the etiology of melanoma and shows that a short amino-acid chain length is shared between the virus-induced antigens and some bacteria
    • Schiavetti F, Thonnard J, Colao D, Boon T, Coulie PG: A human endogenous retroviral sequence encoding an antigen recognised on melanoma by cytolytic T lymphocytes. Cancer Res. 62, 5510-5516 (2002). • Firmly associates a human endogenous retrovirus in the etiology of melanoma and shows that a short amino-acid chain length is shared between the virus-induced antigens and some bacteria.
    • (2002) Cancer Res. , vol.62 , pp. 5510-5516
    • Schiavetti, F.1    Thonnard, J.2    Colao, D.3    Boon, T.4    Coulie, P.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.