메뉴 건너뛰기




Volumn 2, Issue , 2009, Pages 251-260

Rational use of cetuximab in the treatment of advanced non-small cell lung cancer

Author keywords

Cetuximab; Lung cancer; Monoclonal antibody

Indexed keywords

ANTIBIOTIC AGENT; BEVACIZUMAB; BORTEZOMIB; CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; EMOLLIENT AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; GEMCITABINE; NAVELBINE; PACLITAXEL; PANITUMUMAB; PEMETREXED; STEROID;

EID: 77953371486     PISSN: None     EISSN: 11786930     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (1)

References (109)
  • 2
    • 57349182464 scopus 로고    scopus 로고
    • Annual report to the nation on the status of cancer, 1975-2005, featuring trends in lung cancer, tobacco use, and tobacco control
    • Jemal A, Thun MJ, Ries LA, et al; Annual report to the nation on the status of cancer, 1975-2005, featuring trends in lung cancer, tobacco use, and tobacco control. J Natl Cancer Inst. 2008;100:1672-1694.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1672-1694
    • Jemal, A.1    Thun, M.J.2    Ries, L.A.3
  • 3
    • 34548457234 scopus 로고    scopus 로고
    • The IASLC lung cancer staging project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours
    • DOI 10.1097/JTO.0b013e31812f3c1a, PII 0124389420070800000006
    • Goldstraw P, Crowley J, Chansky K, et al; The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J Thorac Oncol. 2007;2:706-714. (Pubitemid 47357522)
    • (2007) Journal of Thoracic Oncology , vol.2 , Issue.8 , pp. 706-714
    • Goldstraw, P.1    Crowley, J.2    Chansky, K.3    Giroux, D.J.4    Groome, P.A.5    Rami-Porta, R.6    Postmus, P.E.7    Rusch, V.8    Sobin, L.9
  • 10
    • 55549138045 scopus 로고    scopus 로고
    • Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups
    • Strauss GM, Herndon JE 2nd, Maddaus MA, et al. Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups. J Clin Oncol. 2008;26:5043-5051.
    • (2008) J Clin Oncol , vol.26 , pp. 5043-5051
    • Strauss, G.M.1    Herndon II, J.E.2    Maddaus, M.A.3
  • 11
    • 20644462118 scopus 로고    scopus 로고
    • Current standards and ongoing controversies in the management of locally advanced non-small cell lung cancer
    • DOI 10.1053/j.seminoncol.2005.02.015, PII S0093775405000849
    • West H, Albain KS. Current standards and ongoing controversies in the management of locally advanced non-small cell lung cancer. Semin Oncol. 2005;32:284-292. (Pubitemid 40834485)
    • (2005) Seminars in Oncology , vol.32 , Issue.3 SOPEC. ISS , pp. 284-292
    • West, H.1    Albain, K.S.2
  • 12
    • 0023849681 scopus 로고
    • A randomized comparative trial of sequential versus alternating cyclophosphamide, doxorubicin, and cisplatin and mitomycin, lomustine, and methotrexate in metastatic non-small-cell lung cancer
    • Eagan RT, Frytak S, Richardson RL, et al. A randomized comparative trial of sequential versus alternating cyclophosphamide, doxorubicin, and cisplatin and mitomycin, lomustine, and methotrexate in metastatic non-small-cell lung cancer. J Clin Oncol. 1988;6:5-8. (Pubitemid 18039984)
    • (1988) Journal of Clinical Oncology , vol.6 , Issue.1 , pp. 5-8
    • Eagan, R.T.1    Frytak, S.2    Richardson, R.L.3    Creagan, E.T.4    Therneau, T.M.5    Coles, D.T.6    Jett, J.R.7
  • 14
    • 0023950534 scopus 로고
    • Trimetrexate and cyclophosphamide for metastatic inoperable nonsmall cell lung cancer
    • Mattson K, Maasilta P, Tammilehto L, et al. Trimetrexate and cyclophosphamide for metastatic inoperable nonsmall cell lung cancer. Semin Oncol. 1988;15:32-37. (Pubitemid 18137169)
    • (1988) Seminars in Oncology , vol.15 , Issue.2 SUPPL. 2 , pp. 32-37
    • Mattson, K.1    Maasilta, P.2    Tammilehto, L.3    Holsti, L.R.4    Grove, W.5
  • 15
    • 0006453669 scopus 로고    scopus 로고
    • Effects of vinorelbine on quality of life and survival of elderly patients with advanced non-small-cell lung cancer
    • The Elderly Lung Cancer Vinorelbine Italian Study Group
    • Effects of vinorelbine on quality of life and survival of elderly patients with advanced non-small-cell lung cancer. The Elderly Lung Cancer Vinorelbine Italian Study Group. J Natl Cancer Inst. 1999;91:66-72.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 66-72
  • 16
    • 0033913982 scopus 로고    scopus 로고
    • Gemcitabine plus best supportive care (BSC) vs BSC in inoperable non-small cell lung cancer - A randomized trial with quality of life as the primary outcome
    • UK NSCLC Gemcitabine Group. Non-Small Cell Lung Cancer
    • Anderson H, Hopwood P, Stephens RJ, et al. Gemcitabine plus best supportive care (BSC) vs BSC in inoperable non-small cell lung cancer - a randomized trial with quality of life as the primary outcome. UK NSCLC Gemcitabine Group. Non-Small Cell Lung Cancer. Br J Cancer. 2000;83:447-453.
    • (2000) Br J Cancer , vol.83 , pp. 447-453
    • Anderson, H.1    Hopwood, P.2    Stephens, R.J.3
  • 17
    • 0033749713 scopus 로고    scopus 로고
    • Management of elderly patients with lung cancer
    • Ranson MR, White S, Thatcher N. Management of elderly patients with lung cancer. Curr Oncol Rep. 2000;2:90-95.
    • (2000) Curr Oncol Rep , vol.2 , pp. 90-95
    • Ranson, M.R.1    White, S.2    Thatcher, N.3
  • 24
    • 62449124416 scopus 로고    scopus 로고
    • Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: Avail
    • Reck M, von Pawel J, Zatloukal P, et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: Avail. J Clin Oncol. 2009;27:1227-1234.
    • (2009) J Clin Oncol , vol.27 , pp. 1227-1234
    • Reck, M.1    Von Pawel, J.2    Zatloukal, P.3
  • 25
    • 49049089802 scopus 로고    scopus 로고
    • Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
    • Scagliotti GV, Parikh P, von Pawel J, et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol. 2008;26:3543-3551.
    • (2008) J Clin Oncol , vol.26 , pp. 3543-3551
    • Scagliotti, G.V.1    Parikh, P.2    Von Pawel, J.3
  • 26
    • 36048959189 scopus 로고    scopus 로고
    • Optimal duration of chemotherapy in advanced non-small cell lung cancer
    • Lustberg MB, Edelman MJ. Optimal duration of chemotherapy in advanced non-small cell lung cancer. Curr Treat Options Oncol. 2007;8:38-46.
    • (2007) Curr Treat Options Oncol , vol.8 , pp. 38-46
    • Lustberg, M.B.1    Edelman, M.J.2
  • 27
    • 36849051803 scopus 로고    scopus 로고
    • Duration of first-line chemotherapy in advanced non small-cell lung cancer: Less is more in the era of effective subsequent therapies
    • Socinski MA, Stinchcombe TE. Duration of first-line chemotherapy in advanced non small-cell lung cancer: less is more in the era of effective subsequent therapies. J Clin Oncol. 2007;25:5155-5157.
    • (2007) J Clin Oncol , vol.25 , pp. 5155-5157
    • Socinski, M.A.1    Stinchcombe, T.E.2
  • 28
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS, Brandt R, Ciardiello F, et al. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol. 1995;19:183-232.
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3
  • 29
    • 0037215106 scopus 로고    scopus 로고
    • Targeting epidermal growth factor receptor in head and neck cancer
    • DOI 10.1002/hed.10224
    • Ford AC, Grandis JR. Targeting epidermal growth factor receptor in head and neck cancer. Head Neck. 2003;25:67-73. (Pubitemid 36005333)
    • (2003) Head and Neck , vol.25 , Issue.1 , pp. 67-73
    • Ford, A.C.1    Grandis, J.R.2
  • 30
    • 0037106273 scopus 로고    scopus 로고
    • Targeting the epidermal growth factor receptor for cancer therapy
    • Mendelsohn J. Targeting the epidermal growth factor receptor for cancer therapy. J Clin Oncol. 2002;20:1S-13S. (Pubitemid 35051707)
    • (2002) Journal of Clinical Oncology , vol.20 , Issue.18 SUPPL.
    • Mendelsohn, J.1
  • 31
    • 33745828702 scopus 로고    scopus 로고
    • EGF-ERBB signalling: Towards the systems level
    • DOI 10.1038/nrm1962, PII NRM1962
    • Citri A, Yarden Y. EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol. 2006;7:505-516. (Pubitemid 44036456)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.7 , pp. 505-516
    • Citri, A.1    Yarden, Y.2
  • 32
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • DOI 10.1038/nrc1609
    • Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer. 2005;5:341-354. (Pubitemid 40637826)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 33
    • 15744378043 scopus 로고    scopus 로고
    • EGR1 predicts PTEN and survival in patients with non-small-cell lung cancer
    • DOI 10.1200/JCO.2005.08.127
    • Ferraro B, Bepler G, Sharma S, et al. EGR1 predicts PTEN and survival in patients with non-small-cell lung cancer. J Clin Oncol. 2005;23:1921-1926. (Pubitemid 46211370)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.9 , pp. 1921-1926
    • Ferraro, B.1    Bepler, G.2    Sharma, S.3    Cantor, A.4    Haura, E.B.5
  • 34
    • 28544438023 scopus 로고    scopus 로고
    • Activated epidermal growth factor receptor-stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer
    • DOI 10.1158/1078-0432.CCR-05-0827
    • Haura EB, Zheng Z, Song L, et al. Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer. Clin Cancer Res. 2005;11:8288-8294. (Pubitemid 41746939)
    • (2005) Clinical Cancer Research , vol.11 , Issue.23 , pp. 8288-8294
    • Haura, E.B.1    Zheng, Z.2    Song, L.3    Cantor, A.4    Bepler, G.5
  • 40
    • 0034332542 scopus 로고    scopus 로고
    • New therapeutic agents targeting the epidermal growth factor receptor
    • Baselga J: New therapeutic agents targeting the epidermal growth factor receptor. J Clin Oncol 2000;18:54S-59S.
    • (2000) J Clin Oncol , vol.18
    • Baselga, J.1
  • 41
    • 0028819660 scopus 로고
    • Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model
    • Goldstein NI, Prewett M, Zuklys K, et al. Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model. Clin Cancer Res. 1995;1:1311-1318.
    • (1995) Clin Cancer Res , vol.1 , pp. 1311-1318
    • Goldstein, N.I.1    Prewett, M.2    Zuklys, K.3
  • 42
    • 0034779291 scopus 로고    scopus 로고
    • The EGFR as a target for anticancer therapy - Focus on cetuximab
    • PII S0959804901002337
    • Baselga J. The EGFR as a target for anticancer therapy - focus on cetuximab. Eur J Cancer. 2001;37 Suppl 4:S16-S22. (Pubitemid 32938125)
    • (2001) European Journal of Cancer , vol.37 , Issue.SUPPL. 4
    • Baselga, J.1
  • 43
    • 0035884307 scopus 로고    scopus 로고
    • Targeting the epidermal growth factor receptor: A clinical reality
    • Baselga J. Targeting the epidermal growth factor receptor: a clinical reality. J Clin Oncol. 2001;19:S41-S44. (Pubitemid 32880078)
    • (2001) Journal of Clinical Oncology , vol.19 , Issue.18 SUPPL.
    • Baselga, J.1
  • 44
    • 33644635247 scopus 로고    scopus 로고
    • A review of EGFR targeted therapy
    • Baselga J. A review of EGFR targeted therapy. Clin Adv Hematol Oncol. 2003;1:218-219.
    • (2003) Clin Adv Hematol Oncol , vol.1 , pp. 218-219
    • Baselga, J.1
  • 47
    • 17444403242 scopus 로고    scopus 로고
    • Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
    • DOI 10.1016/j.ccr.2005.03.003
    • Li S, Schmitz KR, Jeffrey PD, et al. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell. 2005;7:301-311. (Pubitemid 40544648)
    • (2005) Cancer Cell , vol.7 , Issue.4 , pp. 301-311
    • Li, S.1    Schmitz, K.R.2    Jeffrey, P.D.3    Wiltzius, J.J.W.4    Kussie, P.5    Ferguson, K.M.6
  • 48
    • 33749018813 scopus 로고    scopus 로고
    • Clinical implications of the mechanism of epidermal growth factor receptors inhibitors
    • DOI 10.1002/cncr.22133
    • Marshall J. Clinical implications of the mechanism of epidermal growth factor receptor inhibitors. Cancer. 2006;107:1207-1218. (Pubitemid 44452768)
    • (2006) Cancer , vol.107 , Issue.6 , pp. 1207-1218
    • Marshall, J.1
  • 49
    • 48549088895 scopus 로고    scopus 로고
    • Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation
    • Sigismund S, Argenzio E, Tosoni D, et al. Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation. Dev Cell. 2008;15:209-219.
    • (2008) Dev Cell , vol.15 , pp. 209-219
    • Sigismund, S.1    Argenzio, E.2    Tosoni, D.3
  • 50
    • 1342323632 scopus 로고    scopus 로고
    • ErbB Receptors: Directing Key Signaling Networks Throughout Life
    • DOI 10.1146/annurev.pharmtox.44.101802.121440
    • Holbro T, Hynes NE. ErbB receptors: directing key signaling networks throughout life. Annu Rev Pharmacol Toxicol. 2004;44:195-217. (Pubitemid 38263839)
    • (2004) Annual Review of Pharmacology and Toxicology , vol.44 , pp. 195-217
    • Holbro, T.1    Hynes, N.E.2
  • 51
    • 0030693984 scopus 로고    scopus 로고
    • Reciprocal changes in p27(Kip1) and p21(Cip1) in growth inhibition mediated by blockade or overstimulation of epidermal growth factor receptors
    • Fan Z, Shang BY, Lu Y, et al. Reciprocal changes in p27(Kip1) and p21(Cip1) in growth inhibition mediated by blockade or overstimulation of epidermal growth factor receptors. Clin Cancer Res. 1997;3:1943-1948. (Pubitemid 27505119)
    • (1997) Clinical Cancer Research , vol.3 , Issue.11 , pp. 1943-1948
    • Fan, Z.1    Shang, B.Y.2    Lu, Y.3    Chou, J.-L.4    Mendelsohn, J.5
  • 52
    • 0029776415 scopus 로고    scopus 로고
    • 1 arrest in prostatic cancer cell line DU145
    • Peng D, Fan Z, Lu Y, et al. Anti-epidermal growth factor receptor monoclonal antibody 225 up-regulates p27KIP1 and induces G1 arrest in prostatic cancer cell line DU145. Cancer Res. 1996;56:3666-3669. (Pubitemid 26272010)
    • (1996) Cancer Research , vol.56 , Issue.16 , pp. 3666-3669
    • Peng, D.1    Fan, Z.2    Lu, Y.3    Deblasio, T.4    Scher, H.5    Mendelsohn, J.6
  • 53
    • 0029670014 scopus 로고    scopus 로고
    • 1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody
    • Wu X, Rubin M, Fan Z, et al. Involvement of p27KIP1 in G1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody. Oncogene. 1996;12:1397-1403. (Pubitemid 26135156)
    • (1996) Oncogene , vol.12 , Issue.7 , pp. 1397-1403
    • Wu, X.1    Rubin, M.2    Fan, Z.3    Deblasio, T.4    Soos, T.5    Koff, A.6    Mendelsohn, J.7
  • 54
    • 34548404210 scopus 로고    scopus 로고
    • Mechanisms for oncogenic activation of the epidermal growth factor receptor
    • DOI 10.1016/j.cellsig.2007.06.023, PII S089865680700174X
    • Zandi R, Larsen AB, Andersen P, et al. Mechanisms for oncogenic activation of the epidermal growth factor receptor. Cell Signal. 2007;19:2013-2023. (Pubitemid 47353811)
    • (2007) Cellular Signalling , vol.19 , Issue.10 , pp. 2013-2023
    • Zandi, R.1    Larsen, A.B.2    Andersen, P.3    Stockhausen, M.-T.4    Poulsen, H.S.5
  • 56
    • 0027428571 scopus 로고
    • Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenografts
    • Fan Z, Baselga J, Masui H, et al. Antitumor effect of antiepidermal growth factor receptor monoclonal antibodies pluscis-diamminedichloroplatinum on well established A431 cell xenografts. Cancer Res. 1993;53:4637-4642. (Pubitemid 23304392)
    • (1993) Cancer Research , vol.53 , Issue.18 , pp. 4637-4642
    • Fan, Z.1    Baselga, J.2    Masui, H.3    Mendelsohn, J.4
  • 57
    • 0031427295 scopus 로고    scopus 로고
    • Antitumor activity of anti-epidermal growth factor receptor monoclonal antibodies and cisplatin in ten human head and neck squamous cell carcinoma lines
    • Hoffmann T, Hafner D, Ballo H, et al. Antitumor activity of anti-epidermal growth factor receptor monoclonal antibodies and cisplatin in ten human head and neck squamous cell carcinoma lines. Anticancer Res. 1997;17:4419-4425. (Pubitemid 28081723)
    • (1997) Anticancer Research , vol.17 , Issue.6 D , pp. 4419-4425
    • Hoffmann, T.1    Hafner, D.2    Ballo, H.3    Haas, I.4    Bier, H.5
  • 58
    • 0032127350 scopus 로고    scopus 로고
    • Recombinant humanized anti-HER2 antibody (herceptin(TM)) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
    • Baselga J, Norton L, Albanell J, et al. Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res. 1998;58:2825-2831. (Pubitemid 28311914)
    • (1998) Cancer Research , vol.58 , Issue.13 , pp. 2825-2831
    • Baselga, J.1    Norton, L.2    Albanell, J.3    Kim, Y.-M.4    Mendelsohn, J.5
  • 60
    • 0029913172 scopus 로고    scopus 로고
    • Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c- Raf-1 and represents a novel c-Raf-1 signal transduction pathway
    • Blagosklonny MV, Schulte T, Nguyen P, et al. Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway. Cancer Res. 1996;56:1851-1854. (Pubitemid 26118221)
    • (1996) Cancer Research , vol.56 , Issue.8 , pp. 1851-1854
    • Blagosklonny, M.V.1    Schulte, T.2    Nguyen, P.3    Trepel, J.4    Neckers, L.M.5
  • 61
    • 33845455068 scopus 로고    scopus 로고
    • EGF induces cell motility and multi-drug resistance gene expression in breast cancer cells
    • Garcia R, Franklin RA, McCubrey JA. EGF induces cell motility and multi-drug resistance gene expression in breast cancer cells. Cell Cycle. 2006;5:2820-2826. (Pubitemid 44901745)
    • (2006) Cell Cycle , vol.5 , Issue.23 , pp. 2820-2826
    • Garcia, R.1    Franklin, R.A.2    McCubrey, J.A.3
  • 62
    • 40049099220 scopus 로고    scopus 로고
    • The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
    • Yun CH, Mengwasser KE, Toms AV, et al. The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. Proc Natl Acad Sci U S A. 2008;105:2070-2075.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2070-2075
    • Yun, C.H.1    Mengwasser, K.E.2    Toms, A.V.3
  • 63
    • 33745727112 scopus 로고    scopus 로고
    • HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors
    • Wang SE, Narasanna A, Perez-Torres M, et al. HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Cancer Cell. 2006;10:25-38.
    • (2006) Cancer Cell , vol.10 , pp. 25-38
    • Wang, S.E.1    Narasanna, A.2    Perez-Torres, M.3
  • 64
  • 66
    • 34249049000 scopus 로고    scopus 로고
    • Implication of the insulin-like growth factor-IR pathway in the resistance of non-small cell lung cancer cells to treatment with gefitinib
    • DOI 10.1158/1078-0432.CCR-06-2077
    • Morgillo F, Kim WY, Kim ES, et al. Implication of the insulin-like growth factor-IR pathway in the resistance of non-small cell lung cancer cells to treatment with gefitinib. Clin Cancer Res. 2007;13:2795-2803. (Pubitemid 46788049)
    • (2007) Clinical Cancer Research , vol.13 , Issue.9 , pp. 2795-2803
    • Morgillo, F.1    Kim, W.-Y.2    Kim, E.S.3    Ciardiello, F.4    Waun, K.H.5    Lee, H.-Y.6
  • 67
    • 42649145667 scopus 로고    scopus 로고
    • Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
    • Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol. 2008;26:1626-1634.
    • (2008) J Clin Oncol , vol.26 , pp. 1626-1634
    • Amado, R.G.1    Wolf, M.2    Peeters, M.3
  • 68
    • 54949085398 scopus 로고    scopus 로고
    • K-ras mutations and benefit from cetuximab in advanced colorectal cancer
    • Karapetis CS, Khambata-Ford S, Jonker DJ, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med. 2008;359:1757-1765.
    • (2008) N Engl J Med , vol.359 , pp. 1757-1765
    • Karapetis, C.S.1    Khambata-Ford, S.2    Jonker, D.J.3
  • 69
    • 33646228635 scopus 로고    scopus 로고
    • KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
    • Lievre A, Bachet JB, Le Corre D, et al. KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res. 2006;66:3992-3995.
    • (2006) Cancer Res , vol.66 , pp. 3992-3995
    • Lievre, A.1    Bachet, J.B.2    Le Corre, D.3
  • 71
    • 65349116059 scopus 로고    scopus 로고
    • Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): An open-label randomised phase III trial
    • Pirker R, Pereira JR, Szczesna A, et al. Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial. Lancet. 2009;373:1525-1531.
    • (2009) Lancet , vol.373 , pp. 1525-1531
    • Pirker, R.1    Pereira, J.R.2    Szczesna, A.3
  • 72
    • 68949124435 scopus 로고    scopus 로고
    • Molecular and clinical predictors of outcome for cetuximab in non-small cell lung cancer (NSCLC): Data from the FLEX study
    • J Clin Oncol, 2009 ASCO Annual Meeting Proceedings. abstr 8007
    • O'Byrne K, Bondarenko I, Barrios C. Molecular and clinical predictors of outcome for cetuximab in non-small cell lung cancer (NSCLC): Data from the FLEX study. J Clin Oncol, 2009 ASCO Annual Meeting Proceedings. J Clin Oncol. 2009;27:15s, (suppl; abstr 8007).
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL.
    • O'Byrne, K.1    Bondarenko, I.2    Barrios, C.3
  • 75
    • 49149127726 scopus 로고    scopus 로고
    • Increased EGFR gene copy number detected by fluorescent in situ hybridization predicts outcome in non-small-cell lung cancer patients treated with cetuximab and chemotherapy
    • Hirsch FR, Herbst RS, Olsen C, et al. Increased EGFR gene copy number detected by fluorescent in situ hybridization predicts outcome in non-small-cell lung cancer patients treated with cetuximab and chemotherapy. J Clin Oncol. 2008;26:3351-3357.
    • (2008) J Clin Oncol , vol.26 , pp. 3351-3357
    • Hirsch, F.R.1    Herbst, R.S.2    Olsen, C.3
  • 76
    • 0022468532 scopus 로고
    • Expression of epidermal growth factor receptor (EGF-R) in human lung tumours
    • Cerny T, Barnes DM, Hasleton P, et al. Expression of epidermal growth factor receptor (EGF-R) in human lung tumours. Br J Cancer. 1986;54:265-269. (Pubitemid 16076118)
    • (1986) British Journal of Cancer , vol.54 , Issue.2 , pp. 265-269
    • Cerny, T.1    Barnes, D.M.2    Hasleton, P.3
  • 78
    • 33144481184 scopus 로고    scopus 로고
    • Phase I/IIa study of cetuximab with gemcitabine plus carboplatin in patients with chemotherapy-naive advanced non-small-cell lung cancer
    • DOI 10.1200/JCO.2004.00.1438
    • Robert F, Blumenschein G, Herbst RS, et al. Phase I/IIa study of cetuximab with gemcitabine plus carboplatin in patients with chemotherapy-naive advanced non-small-cell lung cancer. J Clin Oncol. 2005;23:9089-9096. (Pubitemid 46264008)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.36 , pp. 9089-9096
    • Robert, F.1    Blumenschein, G.2    Herbst, R.S.3    Fossella, F.V.4    Tseng, J.5    Saleh, M.N.6    Needle, M.7
  • 79
    • 37649022615 scopus 로고    scopus 로고
    • Randomized phase II study of gemcitabine plus cisplatin or carboplatin [corrected], with or without cetuximab, as first-line therapy for patients with advanced or metastatic non small-cell lung cancer
    • Butts CA, Bodkin D, Middleman EL, et al. Randomized phase II study of gemcitabine plus cisplatin or carboplatin [corrected], with or without cetuximab, as first-line therapy for patients with advanced or metastatic non small-cell lung cancer. J Clin Oncol. 2007;25:5777-5784.
    • (2007) J Clin Oncol , vol.25 , pp. 5777-5784
    • Butts, C.A.1    Bodkin, D.2    Middleman, E.L.3
  • 80
    • 77953383439 scopus 로고    scopus 로고
    • Docetaxel, gemcitabine, and cetuximab in untreated advanced non-small cell lung cancer: P3-144
    • 12th World Conference on Lung Cancer; 2007 September 2-6; Seoul, Korea
    • Spigel D, Greco F, Burris H. Docetaxel, gemcitabine, and cetuximab in untreated advanced non-small cell lung cancer: P3-144. 12th World Conference on Lung Cancer; 2007 September 2-6; J Thorac Oncol, Seoul, Korea: 2007;2(8) Suppl 4:S740-S741.
    • (2007) J Thorac Oncol , vol.2 , Issue.8 SUPPL. 4
    • Spigel, D.1    Greco, F.2    Burris, H.3
  • 81
    • 55549127901 scopus 로고    scopus 로고
    • Cetuximab in combination with carboplatin and docetaxel for patients with metastatic or advanced-stage nonsmall cell lung cancer: A multicenter phase 2 study
    • Belani CP, Schreeder MT, Steis RG, et al. Cetuximab in combination with carboplatin and docetaxel for patients with metastatic or advanced-stage nonsmall cell lung cancer: a multicenter phase 2 study. Cancer. 2008;113:2512-2517.
    • (2008) Cancer , vol.113 , pp. 2512-2517
    • Belani, C.P.1    Schreeder, M.T.2    Steis, R.G.3
  • 82
    • 58949087252 scopus 로고    scopus 로고
    • Phase II study of paclitaxel, carboplatin, and cetuximab as first line treatment, for patients with advanced non-small cell lung cancer (NSCLC): Results of OPN-017
    • Borghaei H, Langer CJ, Millenson M, et al. Phase II study of paclitaxel, carboplatin, and cetuximab as first line treatment, for patients with advanced non-small cell lung cancer (NSCLC): results of OPN-017. J Thorac Oncol. 2008;3:1286-1292.
    • (2008) J Thorac Oncol , vol.3 , pp. 1286-1292
    • Borghaei, H.1    Langer, C.J.2    Millenson, M.3
  • 83
    • 55849146855 scopus 로고    scopus 로고
    • Randomized phase II trial of two dose schedules of carboplatin/ paclitaxel/cetuximab in stage IIIB/IV non-small cell lung cancer (NSCLC)
    • ASCO Annual Meeting Proceedings Part I. June 20 Suppl:Abstract 7586
    • Saleh M, Socinski M, Trent D. Randomized phase II trial of two dose schedules of carboplatin/paclitaxel/cetuximab in stage IIIB/IV non-small cell lung cancer (NSCLC). ASCO Annual Meeting Proceedings Part I. J Clin Oncol. 2007;25(18S) June 20 Suppl:Abstract 7586.
    • (2007) J Clin Oncol , vol.25 , Issue.18 S
    • Saleh, M.1    Socinski, M.2    Trent, D.3
  • 84
    • 37649016023 scopus 로고    scopus 로고
    • A phase II randomized selection trial evaluating concurrent chemotherapy plus cetuximab or chemotherapy followed by cetuximab in patients with advanced non-small cell lung cancer (NSCLC): Final report of SWOG 0342
    • ASCO Annual Meeting Proceedings Part I. June 20 Suppl: Abstract 7545
    • Herbst R, Chansky K, Kelly K. A phase II randomized selection trial evaluating concurrent chemotherapy plus cetuximab or chemotherapy followed by cetuximab in patients with advanced non-small cell lung cancer (NSCLC): Final report of SWOG 0342. ASCO Annual Meeting Proceedings Part I. J Clin Oncol. 2007;25(18S) June 20 Suppl: Abstract 7545.
    • (2007) J Clin Oncol , vol.25 , Issue.18 S
    • Herbst, R.1    Chansky, K.2    Kelly, K.3
  • 85
    • 55849104686 scopus 로고    scopus 로고
    • Phase II trial of carboplatin plus cetuximab for the treatment of stage IIIB/IV non-small cell lung cancer (NSCLC)
    • ASCO Annual Meeting Proceedings Part I June 20 Suppl:Abstract 18005
    • Bradford D, Socinski M, LaRocca R. Phase II trial of carboplatin plus cetuximab for the treatment of stage IIIB/IV non-small cell lung cancer (NSCLC). ASCO Annual Meeting Proceedings Part I. J Clin Oncol. 2007;25(18S) June 20 Suppl:Abstract 18005.
    • (2007) J Clin Oncol , vol.25 , Issue.18 S
    • Bradford, D.1    Socinski, M.2    Larocca, R.3
  • 86
    • 38749154518 scopus 로고    scopus 로고
    • Phase II randomized trial of docetaxel plus cetuximab or bortezomib in patients with advanced NSCLC and performance status (PS) 2-CALGB 30402
    • ASCO Annual Meeting Proceedings Part I June 20 Suppl:Abstract 7595
    • Lilenbaum R, Wang X, Gu L. Phase II randomized trial of docetaxel plus cetuximab or bortezomib in patients with advanced NSCLC and performance status (PS) 2-CALGB 30402. ASCO Annual Meeting Proceedings Part I. J Clin Oncol. 2007;25(18S) June 20 Suppl:Abstract 7595.
    • (2007) J Clin Oncol , vol.25 , Issue.18 S
    • Lilenbaum, R.1    Wang, X.2    Gu, L.3
  • 88
    • 51349109631 scopus 로고    scopus 로고
    • FLEX: A randomized, multicenter, phase III study of cetuximab in combination with cisplatin/vinorelbine (CV) versus CV alone in the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC)
    • May 20 Abstract 3
    • Pirker R, Szczesna A, von Pawel J. FLEX: A randomized, multicenter, phase III study of cetuximab in combination with cisplatin/vinorelbine (CV) versus CV alone in the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC). J Clin Oncol. 2008;26:(May 20 Suppl):Abstract 3.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Pirker, R.1    Szczesna, A.2    Von Pawel, J.3
  • 89
    • 39849111354 scopus 로고    scopus 로고
    • A randomized multicenter phase III study of cetuximab (Erbitux®) in combination with Taxane/Carboplatin versus Taxane/Carboplatin alone as first-line treatment for patients with advanced/metastatic Non-small cell lung cancer (NSCLC): B3-03
    • Lynch T, Taral P, Luke D. A randomized multicenter phase III study of cetuximab (Erbitux®) in combination with Taxane/Carboplatin versus Taxane/Carboplatin alone as first-line treatment for patients with advanced/metastatic Non-small cell lung cancer (NSCLC): B3-03. J Thorac Oncol. 2007;2(8) Suppl 4:S340-S341.
    • (2007) J Thorac Oncol , vol.2 , Issue.8 SUPPL. 4
    • Lynch, T.1    Taral, P.2    Luke, D.3
  • 91
    • 55849101937 scopus 로고    scopus 로고
    • Pemetrexed plus cetuximab in patients (pts) with recurrent non-small cell lung cancer (NSCLC): A phase I-IIa dose-ranging study from the Hoosier Oncology Group
    • ASCO Annual Meeting Proceedings Part I June 20 Suppl:Abstract 7698
    • Jalal S, Waterhouse D, Edelman M. Pemetrexed plus cetuximab in patients (pts) with recurrent non-small cell lung cancer (NSCLC): A phase I-IIa dose-ranging study from the Hoosier Oncology Group. ASCO Annual Meeting Proceedings Part I. J Clin Oncol. 2007;25(18S) June 20 Suppl:Abstract 7698.
    • (2007) J Clin Oncol , vol.25 , Issue.18 S
    • Jalal, S.1    Waterhouse, D.2    Edelman, M.3
  • 92
    • 65249157122 scopus 로고    scopus 로고
    • A phase 2 study of cetuximab in combination with docetaxel in chemotherapy-refractory/resistant patients with advanced nonsmall-cell lung cancer
    • Kim ES, Mauer AM, William WN Jr, et al. A phase 2 study of cetuximab in combination with docetaxel in chemotherapy-refractory/resistant patients with advanced nonsmall-cell lung cancer. Cancer. 2009.
    • (2009) Cancer
    • Kim, E.S.1    Mauer, A.M.2    William Jr., W.N.3
  • 94
    • 55849152977 scopus 로고    scopus 로고
    • Safety study of induction chemotherapy and synchronous radiotherapy (RT) and cetuximab in stage III non-small cell lung cancer (NSCLC): SCRATCH (Cohort I)
    • ASCO Annual Meeting Proceedings Part I June 20 Suppl: Abstract 18032
    • Hughes S, Liong J, Miah A. Safety study of induction chemotherapy and synchronous radiotherapy (RT) and cetuximab in stage III non-small cell lung cancer (NSCLC): SCRATCH (Cohort I). ASCO Annual Meeting Proceedings Part I. J Clin Oncol. 2007;25(18S) June 20 Suppl: Abstract 18032.
    • (2007) J Clin Oncol , vol.25 , Issue.18 S
    • Hughes, S.1    Liong, J.2    Miah, A.3
  • 95
    • 65349185779 scopus 로고    scopus 로고
    • A phase II study of cetuximab (C225) in combination with chemoradiation (CRT) in patients (PTS) with stage IIIA/B non-small cell lung cancer (NSCLC): A report of the 2 year and median survival (MS) for the RTOG 0324 trial
    • May 20 Abstract 7516
    • Blumenschein G, Paulus R, Curran W. A phase II study of cetuximab (C225) in combination with chemoradiation (CRT) in patients (PTS) with stage IIIA/B non-small cell lung cancer (NSCLC): A report of the 2 year and median survival (MS) for the RTOG 0324 trial. J Clin Oncol. 2008;26:(May 20 Suppl):Abstract 7516.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Blumenschein, G.1    Paulus, R.2    Curran, W.3
  • 96
    • 66749182764 scopus 로고    scopus 로고
    • A phase II study of pemetrexed, carboplatin and thoracic radiation with or without cetuximab in patients with locally advanced unresectable non-small cell lung cancer: CALGB 30407-Early evaluation of feasibility and toxicity
    • May 20 Abstract 7518
    • Govindan R, Bogart J, Wang X. A phase II study of pemetrexed, carboplatin and thoracic radiation with or without cetuximab in patients with locally advanced unresectable non-small cell lung cancer: CALGB 30407-Early evaluation of feasibility and toxicity. J Clin Oncol. 2008;26:(May 20 Suppl):Abstract 7518.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Govindan, R.1    Bogart, J.2    Wang, X.3
  • 97
    • 33847717475 scopus 로고    scopus 로고
    • Incidence and management of cutaneous toxicities associated with cetuximab
    • DOI 10.1517/14740338.6.2.175
    • Saif MW, Kim R. Incidence and management of cutaneous toxicities associated with cetuximab. Expert Opin Drug Saf. 2007;6:175-182. (Pubitemid 46380811)
    • (2007) Expert Opinion on Drug Safety , vol.6 , Issue.2 , pp. 175-182
    • Saif, M.W.1    Kim, R.2
  • 98
    • 24644513947 scopus 로고    scopus 로고
    • Cutaneous adverse effects with HER1/EGFR-targeted agents: Is there a silver lining?
    • DOI 10.1200/JCO.2005.00.6916
    • Perez-Soler R, Saltz L. Cutaneous adverse effects with HER1/EGFR-targeted agents: is there a silver lining? J Clin Oncol. 2005;23:5235-5246. (Pubitemid 46224035)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.22 , pp. 5235-5246
    • Perez-Soler, R.1    Saltz, L.2
  • 99
    • 33845777130 scopus 로고    scopus 로고
    • Effect of treatment with a colloidal oatmeal lotion on the acneform eruption induced by epidermal growth factor receptor and multiple tyrosine-kinase inhibitors
    • Alexandrescu DT, Vaillant JG, Dasanu CA. Effect of treatment with a colloidal oatmeal lotion on the acneform eruption induced by epidermal growth factor receptor and multiple tyrosine-kinase inhibitors. Clin Exp Dermatol. 2007;32:71-74.
    • (2007) Clin Exp Dermatol , vol.32 , pp. 71-74
    • Alexandrescu, D.T.1    Vaillant, J.G.2    Dasanu, C.A.3
  • 100
    • 34249740340 scopus 로고    scopus 로고
    • Managing dermatologic toxicities of epidermal growth factor receptor inhibitors
    • Chou LS, Garey J, Oishi K, et al. Managing dermatologic toxicities of epidermal growth factor receptor inhibitors. Clin Lung Cancer. 2006;8 Suppl 1:S15-S22.
    • (2006) Clin Lung Cancer , vol.8 , Issue.SUPPL. 1
    • Chou, L.S.1    Garey, J.2    Oishi, K.3
  • 101
    • 42949160079 scopus 로고    scopus 로고
    • Effets secondaires cutanes des nouvelles molecules anticancereuses: Focus sur les molecules ciblant les recepteurs tyrosine kinase et le recepteur a l'EGF
    • DOI 10.1016/S0151-9638(08)70093-0, PII S0151963808700930
    • Deslandres M, Sibaud V, Chevreau C, et al. Cutaneous side effects associated with epidermal growth factor receptor and tyrosine kinase inhibitors. Ann Dermatol Venereol Spec. 2008;1:16-24. (Pubitemid 351620943)
    • (2008) Annales de Dermatologie et de Venereologie , vol.135 , Issue.1 C2 , pp. 16-24
    • Deslandres, M.1    Sibaud, V.2    Chevreau, C.3    Delord, J.P.4
  • 102
    • 33644665064 scopus 로고    scopus 로고
    • Management of rash and other toxicities in patients treated with epidermal growth factor receptor-targeted agents
    • Rhee J, Oishi K, Garey J, et al. Management of rash and other toxicities in patients treated with epidermal growth factor receptor-targeted agents. Clin Colorectal Cancer. 2005;5 Suppl 2:S101-S106.
    • (2005) Clin Colorectal Cancer , vol.5 , Issue.SUPPL. 2
    • Rhee, J.1    Oishi, K.2    Garey, J.3
  • 104
    • 21744437946 scopus 로고    scopus 로고
    • Cetuximab: Adverse event profile and recommendations for toxicity management
    • Thomas M: Cetuximab: adverse event profile and recommendations for toxicity management. Clin J Oncol Nurs. 2005;9:332-338.
    • (2005) Clin J Oncol Nurs , vol.9 , pp. 332-338
    • Thomas, M.1
  • 105
    • 40849142102 scopus 로고    scopus 로고
    • Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3- galactose
    • Chung CH, Mirakhur B, Chan E, et al. Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose. N Engl J Med. 2008;358:1109-11017.
    • (2008) N Engl J Med , vol.358 , pp. 1109-11017
    • Chung, C.H.1    Mirakhur, B.2    Chan, E.3
  • 108
    • 38149034245 scopus 로고    scopus 로고
    • Disorders of renal magnesium handling explain renal magnesium transport
    • Wagner CA. Disorders of renal magnesium handling explain renal magnesium transport. J Nephrol. 2007;20:507-510.
    • (2007) J Nephrol , vol.20 , pp. 507-510
    • Wagner, C.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.