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Volumn 83, Issue 4, 2000, Pages 447-453

Gemcitabine plus best supportive care (BSC) vs BSC in inoperable non-small cell lung cancer - A randomized trial with quality of life as the primary outcome

(14)  Anderson, H a   Hopwood, P b   Stephens, R J c   Thatcher, N b   Cottier, B d   Nicholson, M e   Milroy, R f   Maughan, T S g   Falk, S J h   Bond, M G i   Burt, P A b   Connolly, C K j   McIllmurray, M B k   Carmichael, J l  


Author keywords

BSC; Gemcitabine; NSCLC; Quality of life

Indexed keywords

GEMCITABINE;

EID: 0033913982     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2000.1307     Document Type: Article
Times cited : (322)

References (30)
  • 3
    • 0003277919 scopus 로고    scopus 로고
    • Correlation of quality of life (QOL) with survival, treatment response, and anemia in patients with advanced non-small cell lung cancer (NSCLC) treated with carboplatin and paclitaxel
    • Barsevik A, Langer C, Brunet D, Grindel C, Leighton J and Luckscheider C (1997) Correlation of quality of life (QOL) with survival, treatment response, and anemia in patients with advanced non-small cell lung cancer (NSCLC) treated with carboplatin and paclitaxel [abstract]. Proc Am Soc Clin Oncol 16:44a
    • (1997) Proc Am Soc Clin Oncol , vol.16
    • Barsevik, A.1    Langer, C.2    Brunet, D.3    Grindel, C.4    Leighton, J.5    Luckscheider, C.6
  • 4
    • 0031018391 scopus 로고    scopus 로고
    • Do oncologists have an increasing interest in the quality of life of their patients? A literature review of the last 15 years
    • Batel-Copel M, Kornblith AB and Batel PC (1997) Do oncologists have an increasing interest in the quality of life of their patients? A literature review of the last 15 years. Eur J Cancer 33: 29-32
    • (1997) Eur J Cancer , vol.33 , pp. 29-32
    • Batel-Copel, M.1    Kornblith, A.B.2    Batel, P.C.3
  • 5
    • 0028275927 scopus 로고
    • The EORTC QLQ-LC13: A modular supplement to the EORTC core quality of life questionnaire (QLQ-C30) for use in lung cancer clinical trials
    • Bergman B, Aaronson NK, Ahmedzai S, Kaasa S and Sullivan M (1994) The EORTC QLQ-LC13: a modular supplement to the EORTC core quality of life questionnaire (QLQ-C30) for use in lung cancer clinical trials. Eur J Cancer 30A(5): 635-642
    • (1994) Eur J Cancer , vol.30 A , Issue.5 , pp. 635-642
    • Bergman, B.1    Aaronson, N.K.2    Ahmedzai, S.3    Kaasa, S.4    Sullivan, M.5
  • 6
    • 0000948360 scopus 로고    scopus 로고
    • Workshop on missing data in quality of life research in cancer clinical trials: Practical and methodological issues
    • Bernhard J and Gelber RD (eds) (1998) Workshop on missing data in quality of life research in cancer clinical trials: practical and methodological issues. Stat Med 17: 5-7
    • (1998) Stat Med , vol.17 , pp. 5-7
    • Bernhard, J.1    Gelber, R.D.2
  • 7
    • 0001857996 scopus 로고    scopus 로고
    • Mitomycin, ifosfamide and cisplatin (MIC) in non-small cell lung cancer: 3. Results of a randomised trial evaluating palliation and quality of life
    • Billingham LJ, Cullen MH, Woods AD and Chetiyawardana RC (1997) Mitomycin, ifosfamide and cisplatin (MIC) in non-small cell lung cancer: 3. Results of a randomised trial evaluating palliation and quality of life [abstract]. Lung Cancer 18(Suppl 1): 9
    • (1997) Lung Cancer , vol.18 , Issue.SUPPL. 1 , pp. 9
    • Billingham, L.J.1    Cullen, M.H.2    Woods, A.D.3    Chetiyawardana, R.C.4
  • 8
    • 0021927461 scopus 로고
    • Quality of life in cancer trials
    • Brinkley D (1985) Quality of life in cancer trials. BMJ 291: 685-686
    • (1985) BMJ , vol.291 , pp. 685-686
    • Brinkley, D.1
  • 9
    • 0028969271 scopus 로고
    • Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC)
    • Cox JD, Stetz J and Pajak TF (1995) Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys 31(5): 1341-1346
    • (1995) Int J Radiat Oncol Biol Phys , vol.31 , Issue.5 , pp. 1341-1346
    • Cox, J.D.1    Stetz, J.2    Pajak, T.F.3
  • 10
    • 0027216301 scopus 로고
    • The MIC regimen in non-small cell lung cancer
    • Cullen MH (1993) The MIC regimen in non-small cell lung cancer. Lung Cancer 9(Suppl 2): 81-89
    • (1993) Lung Cancer , vol.9 , Issue.SUPPL. 2 , pp. 81-89
    • Cullen, M.H.1
  • 11
    • 0006453669 scopus 로고    scopus 로고
    • Effects of vinorelbine on quality of life and survival of elderly patients with advanced non-small cell lung cancer
    • Elderly Lung Cancer Vinorelbine Italian Study Group (1999) Effects of vinorelbine on quality of life and survival of elderly patients with advanced non-small cell lung cancer. J Natl Cancer Inst 91: 66-72
    • (1999) J Natl Cancer Inst , vol.91 , pp. 66-72
  • 12
    • 0024477469 scopus 로고
    • Quality of life during chemotherapy in non-small cell lung cancer patients
    • Fernandez C, Rosell R and Abad Esteve A et al (1989) Quality of life during chemotherapy in non-small cell lung cancer patients. Acta Oncol 28: 29-33
    • (1989) Acta Oncol , vol.28 , pp. 29-33
    • Fernandez, C.1    Rosell, R.2    Abad Esteve, A.3
  • 13
    • 0024347325 scopus 로고
    • Symptom relief with moderate dose chemotherapy (mitomycin-C, vinblastine and cisplatin) in advanced non-small cell lung cancer
    • Hardy JR, Noble T and Smith IE (1989) Symptom relief with moderate dose chemotherapy (mitomycin-C, vinblastine and cisplatin) in advanced non-small cell lung cancer. Br J Cancer 60: 764-766
    • (1989) Br J Cancer , vol.60 , pp. 764-766
    • Hardy, J.R.1    Noble, T.2    Smith, I.E.3
  • 14
    • 0000838898 scopus 로고    scopus 로고
    • Five day oral etoposide treatment for advanced small cell lung cancer (SCLC): Quality of life (QOL) assessments in a randomised comparison with intravenous chemotherapy
    • Harper PG, James LE, Spiro SG and Rudd RM (1997) Five day oral etoposide treatment for advanced small cell lung cancer (SCLC): quality of life (QOL) assessments in a randomised comparison with intravenous chemotherapy [abstract]. Lung Cancer (18 Suppl 1): 204
    • (1997) Lung Cancer , vol.18 , Issue.SUPPL. 1 , pp. 204
    • Harper, P.G.1    James, L.E.2    Spiro, S.G.3    Rudd, R.M.4
  • 15
    • 0029807906 scopus 로고    scopus 로고
    • Quality of life assessment in chemotherapy trials for non-small cell lung cancer: Are theory and practice significantly different?
    • Hopwood P (1996) Quality of life assessment in chemotherapy trials for non-small cell lung cancer: are theory and practice significantly different? Semin Oncol 23(5 Suppl 10): 60-64
    • (1996) Semin Oncol , vol.23 , Issue.5 SUPPL. 10 , pp. 60-64
    • Hopwood, P.1
  • 16
    • 0008572417 scopus 로고    scopus 로고
    • Evidence for the impact of quality of life
    • Hopwood P (1997) Evidence for the impact of quality of life. Lung Cancer 18(Suppl 2): 66
    • (1997) Lung Cancer , vol.18 , Issue.SUPPL. 2 , pp. 66
    • Hopwood, P.1
  • 17
    • 0028032893 scopus 로고
    • Approaches to the analysis of quality of life data: Experiences gained from a Medical Research Council Lung Cancer Working Party palliative chemotherapy trial
    • Hopwood P, Stephens RJ and Machin D, for the MRC Lung Cancer Working Party (1994) Approaches to the analysis of quality of life data: experiences gained from a Medical Research Council Lung Cancer Working Party palliative chemotherapy trial. Qual Life Res 3: 339-352
    • (1994) Qual Life Res , vol.3 , pp. 339-352
    • Hopwood, P.1    Stephens, R.J.2    Machin, D.3
  • 18
    • 0028963973 scopus 로고
    • Symptoms at presentation for treatment in patients with lung cancer: Implications for the evaluation of palliative treatment
    • Hopwood P and Stephens RJ, on behalf of the Medical Research Council (MRC) Lung Cancer Working Party (1995) Symptoms at presentation for treatment in patients with lung cancer: implications for the evaluation of palliative treatment. Br J Cancer 7: 633-636
    • (1995) Br J Cancer , vol.7 , pp. 633-636
    • Hopwood, P.1    Stephens, R.J.2
  • 19
    • 0031913005 scopus 로고    scopus 로고
    • Survey of the administration of quality of life (QL) questionnaires in three multicentre randomised trials in cancer
    • Hopwood P, Harvey A, Davies J, Stephens RJ, Girling DJ, Gibson D and Parmar MK (1998) Survey of the administration of quality of life (QL) questionnaires in three multicentre randomised trials in cancer. Eur J Cancer 34(1): 49-57
    • (1998) Eur J Cancer , vol.34 , Issue.1 , pp. 49-57
    • Hopwood, P.1    Harvey, A.2    Davies, J.3    Stephens, R.J.4    Girling, D.J.5    Gibson, D.6    Parmar, M.K.7
  • 20
    • 9044227618 scopus 로고    scopus 로고
    • Randomised trial of four-drug vs less intensive two-drug chemotherapy in the palliative treatment of patients with small-cell lung cancer (SCLC) and poor prognosis
    • MRC LCWP (1996a) Randomised trial of four-drug vs less intensive two-drug chemotherapy in the palliative treatment of patients with small-cell lung cancer (SCLC) and poor prognosis. Br J Cancer 73: 406-413
    • (1996) Br J Cancer , vol.73 , pp. 406-413
  • 21
    • 0010622331 scopus 로고    scopus 로고
    • Randomised trial of palliative two-fraction versus more intensive 13-fraction radiotherapy for patients with inoperable non-small cell lung cancer and good performance status
    • MRC LCWP (1996b). Randomised trial of palliative two-fraction versus more intensive 13-fraction radiotherapy for patients with inoperable non-small cell lung cancer and good performance status. Clin Oncol 8: 167-75
    • (1996) Clin Oncol , vol.8 , pp. 167-175
  • 22
    • 0030870485 scopus 로고    scopus 로고
    • Gemcitabine: A review of its pharmacology and clinical potential in non-small cell lung cancer and pancreatic cancer
    • Noble S and Goa KL (1997) Gemcitabine: a review of its pharmacology and clinical potential in non-small cell lung cancer and pancreatic cancer. Drugs 54: 447-472
    • (1997) Drugs , vol.54 , pp. 447-472
    • Noble, S.1    Goa, K.L.2
  • 23
    • 0028843552 scopus 로고
    • Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials
    • Non-small Cell Lung Cancer Collaborative Group (1995) Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. BMJ 311: 899-909
    • (1995) BMJ , vol.311 , pp. 899-909
  • 24
    • 0016799829 scopus 로고
    • Sequential treatment assignment with balancing of prognostic factors in controlled clinical trials
    • Pocock S and Simon R (1975) Sequential treatment assignment with balancing of prognostic factors in controlled clinical trials. Biometrics 31: 103-115
    • (1975) Biometrics , vol.31 , pp. 103-115
    • Pocock, S.1    Simon, R.2
  • 25
    • 0030837409 scopus 로고    scopus 로고
    • Randomized trials with quality of life endpoints. Are doctors' ratings of patients' physical symptoms interchangeable with patients' self-ratings?
    • Stephens RJ, Hopwood P, Girling DJ and Machin D (1997) Randomized trials with quality of life endpoints. Are doctors' ratings of patients' physical symptoms interchangeable with patients' self-ratings? Qual Life Res 6: 225-236
    • (1997) Qual Life Res , vol.6 , pp. 225-236
    • Stephens, R.J.1    Hopwood, P.2    Girling, D.J.3    Machin, D.4
  • 26
    • 0032928624 scopus 로고    scopus 로고
    • Defining and analysing symptom palliation in cancer clinical trials: A deceptively difficult exercise
    • Stephens RJ, Hopwood P and Girling D (1999) Defining and analysing symptom palliation in cancer clinical trials: a deceptively difficult exercise. Br J Cancer 79: 538-544
    • (1999) Br J Cancer , vol.79 , pp. 538-544
    • Stephens, R.J.1    Hopwood, P.2    Girling, D.3
  • 27
    • 0000049913 scopus 로고
    • A meta-analysis using individual patient data from randomised clinical trials (RCTs) of chemotherapy (CT) in non-small cell lung cancer (NSCLC): (3) Survival in the supportive care setting
    • Stewart LA, Pignon JP, Parmar MKB, Le Chevalier T and Souhami RL, on behalf of the NSCLC Collaborators Group (1994) A meta-analysis using individual patient data from randomised clinical trials (RCTs) of chemotherapy (CT) in non-small cell lung cancer (NSCLC): (3) Survival in the supportive care setting [abstract]. Proc Am Soc Clin Oncol 13: 337
    • (1994) Proc Am Soc Clin Oncol , vol.13 , pp. 337
    • Stewart, L.A.1    Pignon, J.P.2    Parmar, M.K.B.3    Le Chevalier, T.4    Souhami, R.L.5
  • 28
    • 0029558567 scopus 로고
    • Symptomatic benefit from gemcitabine and other chemotherapy in advanced non-small cell lung cancer: Changes in performance status and tumour-related symptoms
    • Thatcher N, Anderson H, Betticher DC and Ranson M (1995) Symptomatic benefit from gemcitabine and other chemotherapy in advanced non-small cell lung cancer: changes in performance status and tumour-related symptoms. Anti-Cancer Drugs 6(Suppl 6): 39-48
    • (1995) Anti-cancer Drugs , vol.6 , Issue.SUPPL. 6 , pp. 39-48
    • Thatcher, N.1    Anderson, H.2    Betticher, D.C.3    Ranson, M.4
  • 29
    • 0030931222 scopus 로고    scopus 로고
    • Improving quality of life in patients with non-small cell lung cancer: Research experience with gemcitabine
    • Thatcher N, Hopwood P and Anderson H (1997) Improving quality of life in patients with non-small cell lung cancer: research experience with gemcitabine. Eur J Cancel 33(Suppl 1): S8-S13
    • (1997) Eur J Cancel , vol.33 , Issue.SUPPL. 1
    • Thatcher, N.1    Hopwood, P.2    Anderson, H.3
  • 30
    • 85040094128 scopus 로고
    • WHO handbook for reporting results of cancer treatment
    • Geneva
    • World Health Organization (1979) WHO Handbook for Reporting Results of Cancer Treatment. World Health Organization 48: Geneva
    • (1979) World Health Organization , vol.48


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