GIPC mediates the generation of reactive oxygen species and the regulation of cancer cell proliferation by insulin-like growth factor-1/IGF-1R signaling

Cancer Letters

Volumn 294, Issue 2, 2010, Pages 254-263

  Choi, Ji Seung ^a   Paek, A Rome ^a   Kim, Soo Youl ^a   You, Hye Jin ^a  

^a National Cancer Center   (South Korea)

Author keywords

GIPC; Growth regulation; IGF 1 signaling; PI3 kinase Akt; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; GAIP INTERACTING PROTEIN C TERMINUS; PDZ PROTEIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER GROWTH; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; FLOW CYTOMETRY; GENE SILENCING; GROWTH REGULATION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BREAST NEOPLASMS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; REACTIVE OXYGEN SPECIES; RECEPTOR, IGF TYPE 1; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 77953356430     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2010.02.007     Document Type: Article

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