Elucidating the pathways of degradation of denagliptin

Journal of Pharmaceutical Sciences

Volumn 99, Issue 7, 2010, Pages 3030-3040

  Joshi, Biren K ^a   Ramsey, Beverly ^a   Johnson, Byron ^a   Patterson, Daniel E ^a   Powers, Jeremiah ^a   Facchine, Kevin L ^a   Osterhout, Martin ^a   Leblanc, Michael P ^a   Bryant Mills, Renetta ^a   Copley, Royston C B ^b   Sides, Scott L ^a  

^a GLAXOSMITHKLINE   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Chemical stability; Formulation; Mass spectrometry; NMR spectroscopy; Preformulation; Solid state stability; Stability

Indexed keywords

AMIDINE; DENAGLIPTIN; PIPERAZINEDIONE;

ACIDITY; ALKALINITY; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG CAPSULE; DRUG DEGRADATION; DRUG STABILITY; EPIMERIZATION; HEAT STRESS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMIDITY; HYDROLYSIS; LIGHT EXPOSURE; SOLID STATE; TABLET FORMULATION; WATER STRESS;

EID: 77953303299     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22069     Document Type: Article

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