Role of salt and excipient properties on disproportionation in the solid-state

Pharmaceutical Research

Volumn 26, Issue 8, 2009, Pages 2015-2026

  Guerrieri, Peter ^a   Taylor, Lynne S ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Disproportionation; Microenvironmental pH; PH solubility; Pharmaceutical salts; Raman spectroscopy

Indexed keywords

BENZOCAINE; DRUG ADDITIVE; EXCIPIENT; MESYLATE SALT; MESYLIC ACID DERIVATIVE; MICONAZOLE; NAPSYLATE SALT; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; CRYSTALLIZATION; DISPROPORTIONATION; DRUG FORMULATION; DRUG SOLUBILITY; HUMIDITY; INFRARED SPECTROSCOPY; IONIZATION; PH MEASUREMENT; PHYSICAL PHASE; PRIORITY JOURNAL; RAMAN SPECTROMETRY; SOLID STATE; SURFACE PROPERTY;

EXCIPIENTS; HYDROGEN-ION CONCENTRATION; PHARMACEUTICAL PREPARATIONS; SALTS; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SPECTRUM ANALYSIS, RAMAN;

EID: 67650084888     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9918-y     Document Type: Article

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