One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer: A nested case-referent study

Cancer Causes and Control

Volumn 21, Issue 4, 2010, Pages 557-566

  Van Guelpen, Bethany ^a   Dahlin, Anna M ^a   Hultdin, Johan ^a   Eklöf, Vincy ^a   Johansson, Ingegerd ^a   Henriksson, Maria L ^a   Cullman, Inger ^a   Hallmans, Göran ^a   Palmqvist, Richard ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

Colorectal cancer; Dna methylation; Folate; Homocysteine; MTHFR; Vitamin b12

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ADENINE; B RAF KINASE; CYANOCOBALAMIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYTOSINE; DNA; FOLIC ACID; HOMOCYSTEINE; NEUROGENIN 1; PROTEIN MLH1; PROTEIN P53; RETINOIC ACID BINDING PROTEIN; SOMATOMEDIN B; SUPPRESSOR OF CYTOKINE SIGNALING 1; THYMINE; TRANSCRIPTION FACTOR RUNX3; VOLTAGE GATED CALCIUM CHANNEL;

ADULT; AGED; ARTICLE; CANCER RISK; CARBON METABOLISM; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; CPG ISLAND; FEMALE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN METHYLATION; RISK REDUCTION; SWEDEN;

AGED; CARBON; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; FEMALE; FOLIC ACID; GENETIC PREDISPOSITION TO DISEASE; HOMOCYSTEINE; HUMANS; INCIDENCE; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SWEDEN; VITAMIN B 12;

EID: 77953293058     PISSN: 09575243     EISSN: 15737225     Source Type: Journal    
DOI: 10.1007/s10552-009-9484-y     Document Type: Article

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