Synthesis and biological activity of α-l-fucosyl ceramides, analogues of the potent agonist, α-d-galactosyl ceramide KRN7000

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 11, 2010, Pages 3223-3226

  Veerapen, Natacha ^a   Reddington, Faye ^a   Bricard, Gabriel ^b   Porcelli, Steven A ^b   Besra, Gurdyal S ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Antigen; CD1d; Ceramide; iNKT; Lipid

Indexed keywords

1 O (ALPHA GALACTOPYRANOSYL) 2 HEXACOSANOYLAMINO 1,3,4 OCTADECANETRIOL; ALPHA LEVO FUCOSYL CERAMIDE; AZIDE; CERAMIDE DERIVATIVE; GLYCOSIDE; IODIDE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; BIOLOGICAL ACTIVITY; CELL EXPANSION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; EX VIVO STUDY; HUMAN; HUMAN CELL; NATURAL KILLER T CELL; SCALE UP; STEREOCHEMISTRY;

ACYLATION; CERAMIDES; GALACTOSYLCERAMIDES; HUMANS; MONOCYTES;

EID: 77953292181     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.04.079     Document Type: Article

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