Anti-IgD antibody attenuates collagen-induced arthritis by selectively depleting mature B-cells and promoting immune tolerance

Journal of Autoimmunity

Volumn 35, Issue 1, 2010, Pages 86-97

  Nguyen, Tue G ^a   Little, Christopher B ^a   Yenson, Vanessa M ^a   Jackson, Christopher J ^a   McCracken, Sharon A ^a   Warning, Julia ^a   Stevens, Veronica ^a   Gallery, Eileen G ^a,b   Morris, Jonathan M ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

Adaptive; Arthritis; Autoimmune; B cell; IgD; Innate; T helper cell; Tolerance

Indexed keywords

AUTOANTIBODY; COLLAGEN; IMMUNOGLOBULIN D ANTIBODY; ANTI-IGD; ANTIIDIOTYPIC ANTIBODY;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IN VIVO STUDY; INNATE IMMUNITY; KNEE; LYMPHOCYTE COUNT; LYMPHOCYTE DEPLETION; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE; TH1 CELL; TH2 CELL; ANIMAL; ARTHRITIS, EXPERIMENTAL; DBA MOUSE; DISEASE COURSE; DRUG EFFECTS; IMMUNOLOGY; IMMUNOTHERAPY; JOINT; LYMPHOCYTE SUBPOPULATION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

ADAPTIVE IMMUNITY; ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ARTHRITIS, EXPERIMENTAL; B-LYMPHOCYTES; DISEASE PROGRESSION; HUMANS; IMMUNE TOLERANCE; IMMUNITY, INNATE; IMMUNOTHERAPY; JOINTS; LYMPHOCYTE DEPLETION; LYMPHOCYTE SUBSETS; MALE; MICE; MICE, INBRED DBA; TH1 CELLS; TH2 CELLS;

EID: 77953290902     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2010.03.003     Document Type: Article

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