Suppression of proteoglycan-induced arthritis by anti-CD20 B cell depletion therapy is mediated by reduction in autoantibodies and CD4+ T cell reactivity

Journal of Immunology

Volumn 180, Issue 7, 2008, Pages 4994-5003

  Hamel, Keith ^a   Doodes, Paul ^a   Cao, Yanxia ^a   Wang, Yumei ^a   Martinson, Jeffrey ^a   Dunn, Robert ^b   Kehry, Marilyn R ^b   Farkas, Balint ^a   Finnegan, Alison ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b BIOGEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACEBUTOLOL; AUTOANTIBODY; CD20 ANTIBODY; GAMMA INTERFERON; INTERLEUKIN 4; PROTEOGLYCAN; CD20 ANTIGEN; MONOCLONAL ANTIBODY;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; FEMALE; IMMUNOREACTIVITY; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SEVERE COMBINED IMMUNODEFICIENCY; T LYMPHOCYTE; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED DISORDER; IMMUNOLOGY; IMMUNOTHERAPY; PATHOLOGY;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD20; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; FEMALE; IMMUNOTHERAPY; MICE; PROTEOGLYCANS;

EID: 44449094628     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.7.4994     Document Type: Article

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