Neurturin effects on nigrostriatal dopamine release and content: Comparison with GDNF

Neurochemical Research

Volumn 35, Issue 5, 2010, Pages 727-734

  Cass, Wayne A ^a   Peters, Laura E ^a  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

Dopamine; GDNF; Microdialysis; Neurturin; Striatum; Substantia nigra

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; AMPHETAMINE; DOPAMINE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; HOMOVANILLIC ACID; NEURTURIN; POTASSIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOPAMINE RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MICRODIALYSIS; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PRIORITY JOURNAL; RAT; STRIATE CORTEX; SUBSTANTIA NIGRA;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; CORPUS STRIATUM; DOPAMINE; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HOMOVANILLIC ACID; MALE; NEURTURIN; RATS; RATS, INBRED F344; SUBSTANTIA NIGRA;

ANIMALIA; RATTUS;

EID: 77953290370     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-010-0128-0     Document Type: Article

References (37)

1. Hudson J, Granholm A-C, Gerhardt GA et al (1995) Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo. Brain Res Bull 36:425-432
2. Martin D, Miller G, Cullen T et al (1996) Intranigral or intrastriatal injections of GDNF: effects on monoamine levels and behavior in rats. Eur J Pharmacol 317:247-256
3. Hebert MA, Van Horne CG, Hoffer BJ et al (1996) Functional effects of GDNF in normal rat striatum: presynaptic studies using in vivo electrochemistry and microdialysis. J Pharmacol Exp Ther 279:1181-1190
4. Xu K, Dluzen DE (2000) The effect of GDNF on nigrostriatal dopaminergic function in response to a two-pulse K+ stimulation. Exp Neurol 166:450-457
5. Rosenblad C, Georgievska B, Kirik D (2003) Long-term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system. Eur J Neurosci 17:260-270
6. Salvatore MF, Zhang J-L, Large DM et al (2004) Striatal GDNF administration increases tyrosine hydroxylase phosphorylation in the rat striatum and substantia nigra. J Neurochem 90:245-254
7. Kobayashi S, Ogren SO, Hoffer BJ et al (1998) Dopamine D1 and D2 receptor-mediated acute and long-lasting behavioral effects of glial cell line-derived neurotrophic factor administered into the striatum. Exp Neurol 154:302-314
8. Emerich DF, Plone M, Francis J et al (1996) Alleviation of behavioral deficits in aged rodents following implantation of encapsulated GDNF-producing fibroblasts. Brain Res 736:99-110
9. Hebert MA, Gerhardt GA (1997) Behavioral and neurochemical effects of intranigral administration of glial cell line-derived neurotrophic factor on aged Fischer 344 rats. J Pharmacol Exp Ther 282:760-768
10. Lapchak PA, Miller PJ, Jiao S (1997) Glial cell line-derived neurotrophic factor induces the dopaminergic and cholinergic phenotype and increases locomotor activity in aged Fischer 344 rats. Neuroscience 77:745-752
11. Grondin R, Cass WA, Zhang Z et al (2003) Glial cell line-derived neurotrophic factor increases stimulus-evoked dopamine release and motor speed in aged rhesus monkeys. J Neurosci 23: 1974-1980
12. Kotzbauer PT, Lampe PA, Heuckeroth RO et al (1996) Neurturin, a relative of glial-cell-line-derived neurotrophic factor. Nature 384:467-470
13. Horger BA, Nishimura MC, Armanini MP et al (1998) Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons. J Neurosci 18:4929-4937
14. Akerud P, Alberch J, Eketjall S et al (1999) Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons. J Neurochem 73:70-78
15. Zihlmann KB, Ducray AD, Schaller B et al (2005) The GDNF family members neurturin, artemin and persephin promote the morphological differentiation of cultured ventral mesencephalic dopaminergic neurons. Brain Res Bull 68:42-53
16. Hoane MR, Gulwadi AG, Morrison S et al (1999) Differential in vivo effects of neurturin and glial cell-line-derived neurotrophic factor. Exp Neurol 160:235-243
17. Hamilton JF, Morrison PF, Chen MY et al (2001) Heparin coinfusion during convection-enhanced delivery (CED) increases the distribution of the glial-derived neurotrophic factor (GDNF) ligand family in rat striatum and enhances the pharmacological activity of neurturin. Exp Neurol 168:155-161
18. Moghaddam B, Bunney BS (1989) Ionic composition of microdialysis perfusing solution alters the pharmacological responsiveness and basal outflow of striatal dopamine. J Neurochem 53:652-654
19. Cass WA, Harned ME, Peters LE et al (2003) HIV-1 protein tat potentiation of methamphetamine-induced decreases in evoked overflow of dopamine in the striatum of the rat. Brain Res 984:133-142
20. Glick SD, Dong N, Keller RW Jr et al (1994) Estimating extracellular concentrations of dopamine and 3, 4-dihydroxyphenylacetic acid in nucleus accumbens and striatum using microdialysis: relationships between in vitro and in vivo recoveries. J Neurochem 62:2017-2021
21. Cass WA, Manning MW (1999) GDNF protection against 6-OHDA-induced reductions in potassium-evoked overflow of striatal dopamine. J Neurosci 19:1416-1423
22. Pothos EN, Davila V, Sulzer D (1998) Presynaptic recording of quanta from midbrain dopamine neurons and modulation of the quantal size. J Neurosci 18:4106-4118.
23. Eisenhofer G, Kopin IJ, Goldstein DS (2004) Catecholamine metabolism: a contemporary view with implications for physiology and medicine. Pharmacol Rev 56:331-349
24. Wood PL, Alter CA (1988) Dopamine release in vivo from nigrostriatal, mesolimbic, and mesocortical neurons: utility of 3-methoxytyramine measurements. Pharmacol Rev 40:163-187
25. Zetterstrom T, Sharp T, Collin AK et al (1988) In vivo measurement of extracellular dopamine and DOPAC in rat striatum after various dopamine-releasing drugs; implications for the origin of extracellular DOPAC. Eur J Pharmacol 148:327-334
26. Salvatore MF, Gerhardt GA, Dayton RD et al (2009) Bilateral effects of unilateral GDNF administration on dopamine- and GABA-regulating proteins in the rat nigrostriatal system. Exp Neurol 219:197-207
27. Robertson GS, Robertson HA (1989) Evidence that L-dopainduced rotational behavior is dependent on both striatal and nigral mechanisms. J Neurosci 9:3326-3331
28. Trevitt JT, Carlson BB, Nowend K et al (2001) Substantia nigra pars reticulata is a highly potent site of action for the behavioral effects of the D1 antagonist SCH 23390 in the rat. Psychopharmacology 156:32-41
29. Gerhardt GA, Cass WA, Yi A et al (2002) Changes in somatodendritic but not terminal dopamine regulation in aged rhesus monkeys. J Neurochem 80:168-177
30. Hoffman AF, Van Horne CG, Eken S et al (1997) In vivo microdialysis studies of somatodendritic dopamine release in the rat substantia nigra: effects of unilateral 6-OHDA lesions and GDNF. Exp Neurol 147:130-147
31. Baloh RH, Enomoto H, Johnson EM Jr et al (2000) The GDNF family ligands and receptors-implications for neural development. Curr Opin Neurobiol 10:103-110
32. Airaksinen MS, Saarma M (2002) The GDNF family: signaling, biological functions and therapeutic value. Nat Rev Neurosci 3:383-394
33. Widenfalk J, Nosrat C, Tomac A et al (1997) Neurturin and glial cell line-derived neurotrophic factor receptor-β (GDNFR-β), novel proteins related to GDNF and GDNFR-a with specific cellular patters of expression suggesting roles in the developing and adult nervous system and in peripheral organs. J Neurosci 17:8506-8519
34. Golden JP, Baloh RH, Kotzbauer PT et al (1998) Expression of neurturin, GDNF, and their receptors in the adult mouse CNS. J Comp Neurol 398:139-150
35. Burazin TCD, Gundlach AL (1999) Localization of GDNF/ neurturin receptor (c-ret, GFRa-1 and a-2) mRNAs in postnatal rat brain: differential regional and temporal expression in hippocampus, cortex and cerebellum. Mol Brain Res 73:151-171
36. Kozlowski DA, Miljan EA, Bremer EG et al (2004) Quantitative analysis of GFRa-1 and GFRa-2 mRNAs and tyrosine hydroxylase protein in the nigrostriatal system reveal bilateral compensatory changes following unilateral 6-OHDA lesions in the rat. Brain Res 1016:170-181
37. Rosenblad C, Kirik D, Devaux B et al (1999) Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle. Eur J Neurosci 11:1554-1566