Anti-Giardia activity of phenolic-rich essential oils: Effects of Thymbra capitata, Origanum virens, Thymus zygis subsp. sylvestris, and Lippia graveolens on trophozoites growth, viability, adherence, and ultrastructure

Parasitology Research

Volumn 106, Issue 5, 2010, Pages 1205-1215

  Machado, Marisa ^a,b   Dinis, Augusto M ^c   Salgueiro, Ligia ^a   Cavaleiro, Carlos ^a   Custódio, José B A ^d   Do Céu Sousa, Maria ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b Instituto Politécnico de Saúde do Norte   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA PHELLANDRENE; ALPHA THUJENE; BETA ELEMENE; BETA PHELLANDRENE; BETA PINENE; BORNEOL; CAMPHENE; CAMPHOR; CARVACROL; CINEOLE; COPAENE; ESSENTIAL OIL; HERBACEOUS AGENT; HUMULENE; LIMONENE; LINALOOL; LIPPIA GRAVEOLENS EXTRACT; MYRCENE; OCIMENE; ORIGANUM VIRENS EXTRACT; PARA CYMENE; PINENE; SABINENE; TERPINENE; TERPINEOL; TERPINOLENE; THYMBRA CAPITATA EXTRACT; THYMOL; THYMUS ZYGIS EXTRACT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DETERMINATION; GIARDIA LAMBLIA; IC 50; IN VITRO STUDY; LIPPIA GRAVEOLENS; MEDICINAL PLANT; MOUSE; NONHUMAN; ORIGANUM VIRENS; PARASITE VIABILITY; PRIORITY JOURNAL; THYMBRA CAPITATA; THYMUS ZYGIS; TROPHOZOITE; ULTRASTRUCTURE;

ANIMALS; CATTLE; CELL ADHESION; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; ENDOTHELIAL CELLS; GIARDIA LAMBLIA; INHIBITORY CONCENTRATION 50; LAMIACEAE; LIPPIA; MACROPHAGES; MICE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; OILS, VOLATILE; PHENOLS; TROPHOZOITES;

GIARDIA; GIARDIA INTESTINALIS; LIPPIA GRAVEOLENS; MAMMALIA; ORIGANUM; PROTOZOA; THYMBRA CAPITATA; THYMUS ZYGIS;

EID: 77953289947     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00436-010-1800-7     Document Type: Article

References (47)

1. Abodeely M, DuBois KN, Hehl A et al (2009) A contiguous compartment functions as endoplasmic reticulum and endosome/lysosome in Giardia lamblia. Eukaryot Cell 8:1665-1676
2. Abonyi A (1995) Examination of nonflagellate and flagellate round forms of Trichomonas vaginalis by transmission electron microscopy. Appl Parasitol 36:303-310
3. Adam RD (2001) Biology of Giardia lamblia. Clin Microbiol Rev 14:447-475
4. Adams RP (1995) Identification of essential oils components by gas chromatography/mass spectroscopy. Allured Publishing Corporation, Carol Stream
5. Barbosa E, Calzada F, Campos R (2007) In vivo antigiardial activity of three flavonoids isolated of some medicinal plants used in Mexican traditional medicine for the treatment of diarrhea. J Ethnopharmacol 109:552-554
6. Burt S (2004) Essential oils: their antibacterial properties and potential applications in foods - a review. Int J Food Microbiol 94:223-253
7. Busatti HG, Vieira AE, Viana JC et al (2007) Effect of metronidazole analogues on Giardia lamblia cultures. Parasitol Res 102:145-149
8. Calzada F, Yepez-Mulia L, Aguilar A (2006) In vitro susceptibility of Entamoeba histolytica and Giardia lamblia to plants used in Mexican traditional medicine for the treatment of gastrointestinal disorders. J Ethnopharmacol 108:367-370
9. Council of Europe (1997) European Pharmacopoeia. Europe Co., Strasbourg
10. Cristani M, D'Arrigo M, Mandalari G et al (2007) Interaction of four monoterpenes contained in essential oils with model membranes: implications for their antibacterial activity. J Agric Food Chem 55:6300-6308
11. Custodio JB, Moreno AJ, Wallace KB (1998) Tamoxifen inhibits induction of the mitochondrial permeability transition by Ca2+ and inorganic phosphate. Toxicol Appl Pharmacol 152:10-17
12. de Almeida I, Alviano DS, Vieira DP et al (2007) Antigiardial activity of Ocimum basilicum essential oil. Parasitol Res 101:443-452
13. Denizot F, Lang R (1986) Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods 89:271-277
14. Dorman HJ, Deans SG (2000) Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol 88:308-316
15. Eckmann L (2003) Mucosal defences against Giardia. Parasite Immunol 25:259-270
16. Edinger AL, Thompson CB (2004) Death by design: apoptosis, necrosis and autophagy. Curr Opin Cell Biol 16:663-669
17. Edris AE (2007) Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: a review. Phytother Res 21:308-323
18. Elmendorf HG, Dawson SC, McCaffery JM (2003) The cytoskeleton of Giardia lamblia. Int J Parasitol 33:3-28
19. Faleiro L, Miguel G, Gomes S et al (2005) Antibacterial and antioxidant activities of essential oils isolated from Thymbra capitata L. (Cav.) and Origanum vulgare L. J Agric Food Chem 53:8162-8168
20. Flanagan PA (1992) Giardia - diagnosis, clinical course and epidemiology. A review. Epidemiol Infect 109:1-22
21. Fraser D, Bilenko N, Deckelbaum RJ et al (2000) Giardia lamblia carriage in Israeli Bedouin infants: risk factors and consequences. Clin Infect Dis 30:419-424
22. Gadelha AP, Vidal F, Castro TM et al (2005) Susceptibility of Giardia lamblia to Hovenia dulcis extracts. Parasitol Res 97:399-407
23. Gardner TB, Hill DR (2001) Treatment of giardiasis. Clin Microbiol Rev 14:114-128
24. Gillin FD, Reiner DS (1982) Attachment of the flagellate Giardia lamblia: role of reducing agents, serum, temperature, and ionic composition. Mol Cell Biol 2:369-377
25. Gonçalves MJ, Vicente AM, Cavaleiro C et al (2007) Composition and antifungal activity of the essential oil of Mentha cervina from Portugal. Nat Prod Res 21:867-871
26. Hansen WR, Tulyathan O, Dawson SC et al (2006) Giardia lamblia attachment force is insensitive to surface treatments. Eukaryot Cell 5:781-783
27. Harris JC, Plummer S, Turner MP et al (2000) The microaerophilic flagellate Giardia intestinalis: Allium sativum (garlic) is an effective antigiardial. Microbiology 146:3119-3127
28. Hill DR, Pohl R, Pearson RD (1986) Giardia lamblia: a culture method for determining parasite viability. Am J Trop Med Hyg 35:1129-1133
29. Holberton DV (1973) Fine structure of the ventral disk apparatus and the mechanism of attachment in the flagellate Giardia muris. J Cell Sci 13:11-41
30. Holberton DV (1974) Attachment of Giardia - a hydrodynamic model based on flagellar activity. J Exp Biol 60:207-221
31. Joulain D, König W (1998) The atlas of spectral data of sesquiterpene hydrocarbons. E. B., Hamburg
32. Keister DB (1983) Axenic culture of Giardia lamblia in TYI-S-33 medium supplemented with bile. Trans R Soc Trop Med Hyg 77:487-488
33. Lanfredi-Rangel A, Attias M, de Carvalho TM et al (1998) The peripheral vesicles of trophozoites of the primitive protozoan Giardia lamblia may correspond to early and late endosomes and to lysosomes. Struct Biol 123:225-235
34. Machado M, Sousa MC, Salgueiro L et al (2010) Effects of essential oils on the growth of Giardia lamblia trophozoites. Nat Prod Commun 5:137-141
35. Moon T, Wilkinson JM, Cavanagh HM (2006) Antiparasitic activity of two Lavandula essential oils against Giardia duodenalis, Trichomonas vaginalis and Hexamita inflata. Parasitol Res 99:722-728
36. Niven GW, Miles CA, Mackey BM (1999) The effects of hydrostatic pressure on ribosome conformation in Escherichia coli: and in vivo study using differential scanning calorimetry. Microbiology 145:419-425
37. Park JH, Schofield PJ, Edwards MR (1997) Giardia intestinalis: volume recovery in response to cell swelling. Exp Parasitol 86:19-28
38. Perez-Arriaga L, Mendoza-Magana ML, Cortes-Zarate R et al (2006) Cytotoxic effect of curcumin on Giardia lamblia trophozoites. Acta Trop 98:152-161
39. Ponce-Macotela M, Rufino-Gonzalez Y, Gonzalez-Maciel A et al (2006) Oregano (Lippia spp.) kills Giardia intestinalis trophozoites in vitro: antigiardiasic activity and ultrastructural damage. Parasitol Res 98:557-560
40. Santoro GF, das Gracas Cardoso M et al (2007) Effect of oregano (Origanum vulgare L.) and thyme (Thymus vulgaris L.) essential oils on Trypanosoma cruzi (Protozoa: Kinetoplastida) growth and ultrastructure. Parasitol Res 100:783-790
41. Sawangjaroen N, Subhadhirasakul S, Phongpaichit S et al (2005) The in vitro anti-giardial activity of extracts from plants that are used for self-medication by AIDS patients in southern Thailand. Parasitol Res 95:17-21
42. Silva MT, Appelberg R, Silva MN et al (1987) In vivo killing and degradation of Mycobacterium aurum within mouse peritoneal macrophages. Infect Immun 55:2006-2016
43. Sousa MC, Poiares-Da-Silva J (1999) A new method for assessing metronidazole susceptibility of Giardia lamblia trophozoites. Antimicrob Agents Chemother 43:2939-2942
44. Sousa MC, Goncalves CA, Bairos VA et al (2001) Adherence of Giardia lamblia trophozoites to Int-407 human intestinal cells. Clin Diagn Lab Immunol 8:258-265
45. Thompson RC (2000) Giardiasis as a re-emerging infectious disease and its zoonotic potential. Int J Parasitol 30:1259-1267
46. Upcroft P, Upcroft JA (2001) Drug targets and mechanisms of resistance in the anaerobic protozoa. Clin Microbiol Rev 14:150-164
47. Vidal F, Vidal JC, Gadelha AP et al (2007) Giardia lamblia: the effects of extracts and fractions from Mentha x piperita Lin. (Lamiaceae) on trophozoites. Exp Parasitol 115:25-31