Identification of proteins regulated by estradiol in focal cerebral ischemic injury-A proteomics approach

Neuroscience Letters

Volumn 477, Issue 2, 2010, Pages 66-71

  Sung, Jin Hee ^a   Cho, Eun Hae ^a   Min, Wongi ^a   Kim, Mi Jeong ^a   Kim, Myeong Ok ^a   Jung, Eun Jung ^b   Koh, Phil Ok ^a  

^a Gyeongsang National University   (South Korea)

^b Gyeongsang National University School of Medicine   (South Korea)

Author keywords

Estradiol; Neuroprotection; Proteomics

Indexed keywords

ESTRADIOL; GLUTAMIC ACID; HEAT SHOCK PROTEIN 60; OIL; PHOSPHOPROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN PEA 15; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; MASS SPECTROMETRY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; REGULATORY MECHANISM; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

ANIMALS; CEREBRAL CORTEX; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ESTRADIOL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MASS SPECTROMETRY; NEUROPROTECTIVE AGENTS; OVARIECTOMY; PROTEOMICS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77953287960     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.04.028     Document Type: Article

References (34)

1. Araujo H., Danziger N., Cordier J., Glowinski J., Chneiweiss H. Characterization of PEA-15, a major substrate for protein kinase C in astrocytes. J. Biol. Chem. 1993, 268:5911-5920.
2. Behl C., Widmann M., Trapp T., Holsboer F. 17β-Estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochem. Biophys. Res. Commun. 1995, 216:473-482.
3. Behl C., Skutella T., Lezoualch F., Post A., Widmann M., Newton C.J., Holsboer F. Neuroprotection against oxidative stress by estrogens: structure-activity relationship. Mol. Pharmaco1. 1997, 51:535-541.
4. Bulteau A.L., Lundberg K.C., Humphries K.M., Sadek H.A., Szweda P.A., Friguet B., Szweda L.I. Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion. J. Biol. Chem. 2001, 276:30057-30063.
5. Chen A., Liao W.P., Lu Q., Wong W.S., Wong P.T. Upregulation of dihydropyrimidinase-related protein 2, spectrin alpha II chain, heat shock cognate protein 70 pseudogene 1 and tropomodulin 2 after focal cerebral ischemia in rats-a proteomics approach. Neurochem. Int. 2007, 50:1078-1086.
6. Chiueh C., Lee S., Andoh T., Murphy D. Induction of antioxidative and antiapoptotic thioredoxin supports neuroprotective hypothesis of estrogen. Endocrine 2003, 21:27-31.
7. Dubal D.B., Kashon M.L., Pettigrew L.C., Ren J.M., Finklestein S.P., Rau S.W., Wise P.M. Estradiol protects against ischemic injury. J. Cereb. Blood Flow. Metab. 1998, 18:1253-1258.
8. Gerstner B., Sifringer M., Dzietko M., Schüller A., Lee J., Simons S., Obladen M., Volpe J.J., Rosenberg P.A., Felderhoff-Mueser U. Estradiol attenuates hyperoxia-induced cell death in the developing white matter. Ann. Neurol. 2007, 61:562-573.
9. Gong C.K., Lidsky T., Wegiel J., Zuck L., Grundke-Iqbal I., Iqbal K. Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease. J. Biol. Chem. 2000, 275:5535-5544.
10. Green P.S., Gridley K.E., Simpkins J.W. Estradiol protects against β-amyloid (25-35)-induced toxicity in SK-N-SH human neuroblastoma cells. Neurosci. Lett. 1996, 218:165-168.
11. Hattori I., Takagi Y., Nakamura H., Nozaki K., Bai J., Kondo N., Sugino T., Nishimura M., Hashimoto N., Yodoi J. Intravenous administration of thioredoxin decreases brain damage following transient focal cerebral ischemia in mice. Antioxid. Redox Signal. 2004, 6:81-87.
12. Hattori T., Takei N., Mizuno Y., Kato K., Kohsaka S. Neurotrophic and neuroprotective effects of neuron-specific enolase on cultured neurons from embryonic rat brain. Neurosci. Res. 1995, 21:191-198.
13. Izaki K., Kinouchi H., Watanabe K., Owada Y., Okubo A., Itoh H., Kondo H., Tashima Y., Tamura S., Yoshimoto T., Mizoi K. Induction of mitochondrial heat shock protein 60 and 10 mRNAs following transient focal cerebral ischemia in the rat. Brain Res. Mol. Brain Res. 2001, 88:14-25.
14. Janssens V., Goris J. Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem. J. 2001, 353:417-439.
15. Koh P.O. Estradiol prevents the injury-induced decrease of 90 ribosomal S6 kinase (p90RSK) and Bad phosphorylation. Neurosci. Lett. 2007, 412:68-72.
16. Koh P.O. 17beta-estradiol prevents the glutamate-induced decrease of Akt and its downstream targets in HT22 cells. J. Vet. Med. Sci. 2007, 285-288.
17. Krueger J., Chou F.L., Glading A., Schaefer E., Ginsberg M.H. Phosphorylation of phosphoprotein enriched in astrocytes (PEA-15) regulates extracellular signal-regulated kinase-dependent transcription and cell proliferation. Mol. Biol. Cell 2005, 16:3552-3561.
18. Longa E.Z., Weinstein P.R., Carlson S., Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989, 20:84-91.
19. Maher P., Davis J.B. The role of monoamine metabolism in oxidative glutamate toxicity. J. Neurosci. 1996, 16(1996):6394-6401.
20. Mize A.L., Shapiro R.A., Dorsa D.M. Estrogen receptor-mediated neuroprotection from oxidative stress requires activation of the mitogen-activated protein kinase pathway. Endocrinology 2003, 144:306-312.
21. Okubo A., Kinouchi H., Owada Y., Kunizuka H., Itoh H., Izaki K., Kondo H., Tashima Y., Yoshimoto T., Mizoi K. Simultaneous induction of mitochondrial heat shock protein mRNAs in rat forebrain ischemia. Brain Res. Mol. Brain Res. 2000, 84:127-134.
22. Oliver C.N., Starke-Reed P.E., Stadtman E.R., Liu G.J., Carney J.M., Floyd R.A. Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proc. Natl. Acad. Sci. U.S.A. 1990, 87:5144-5147.
23. Paganini-Hill A., Henderson V.W. Estrogen replacement therapy and risk of Alzheimer disease. Arch. Intern. Med. 1996, 156:2213-2217.
24. Pearson G., Robinson F., Beers Gibson T., Xu B.E., Karandikar M., Berman K., Cobb M.H. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr. Rev. 2001, 22:153-183.
25. Perry G., Cash A.D., Smith M.A. Alzheimer disease and oxidative stress. J. Biomed. Biotechnol. 2002, 2:120-123.
26. Quinn C.C., Gray G.E., Hockfield S. A family of proteins implicated in axon guidance and outgrowth. J. Neurobiol. 1999, 41:158-164.
27. Schmechel D.E., Brightman M.W., Marangos P.J. Neurons switch from non-neuronal enolase to neuron-specific enolase during differentiation. Brain Res. 1980, 190:195-214.
28. Sharif A., Canton B., Junier M.P., Chneiweiss H. PEA-15 modulates TNFalpha intracellular signaling in astrocytes. Ann. N. Y. Acad. Sci. 2003, 1010:43-50.
29. Shea T.B., Ortiz D. 17β-Estradiol alleviates synergistic oxidative stress resulting from folate deprivation and amyloid-β treatment. J. Alzheimers Dis. 2003, 5:323-327.
30. Sontag E. Protein phosphatase 2A: the Trojan Horse of cellular signaling. Cell Signal. 2001, 13:7-16.
31. Stone S.R., Hofsteenge J., Hemmings B.A. Molecular cloning of cDNAs encoding two isoforms of the catalytic subunit of protein phosphatase 2A. Biochemistry 1987, 26:7215-7220.
32. Strack S., Zaucha J.A., Ebner F.F., Colbran R.J., Wadzinski B.E. Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits. J. Comp. Neurol. 1998, 392:515-527.
33. Yi K.D., Chung J., Pang P., Simpkins J.W. Role of protein phosphatases in estrogen-mediated neuroprotection. Neuroscience 2005, 25:7191-7198.
34. Yi K.D., Simpkins J.W. Protein phosphatase 1, protein phosphatase 2A, and calcineurin play a role in estrogen-mediated neuroprotection. Endocrinology 2008, 149:5235-5243.