Involvement of central β2-adrenergic, NMDA and thromboxane A2 receptors in the pressor effect of anandamide in rats

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 381, Issue 4, 2010, Pages 349-360

  Malinowska, B ^a   Zakrzeska, A ^a   Kurz, C M ^b   Gothert M ^a,b   Kwolek, G ^a   Wielgat, P ^a   Braszko, J J ^a   Schlicker, E ^b  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

2 adrenoceptors; Anandamide; Cannabinoid receptors; NMDA receptors; Thromboxane A2 receptor; TRPV1 receptor

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ANANDAMIDE; BETA 2 ADRENERGIC RECEPTOR; CANNABINOID; DALTROBAN; DIZOCILPINE; FUREGRELATE; HYDROCORTISONE; METHANANDAMIDE; N METHYL DEXTRO ASPARTIC ACID; SULOTROBAN; THROMBOXANE A2 RECEPTOR; AMIDE; ARACHIDONIC ACID DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; CATECHOLAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ADRENAL FUNCTION; ADRENALECTOMY; ANIMAL TISSUE; ARTICLE; CATECHOLAMINE RELEASE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG RESPONSE; LIGAND BINDING; MALE; NONHUMAN; PRESSOR RESPONSE; RAT; ADRENAL GLAND; ANIMAL; DOSE RESPONSE; DRUG EFFECT; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; SECRETION; WISTAR RAT;

ADRENAL GLANDS; ANIMALS; ARACHIDONIC ACIDS; CALCIUM CHANNEL BLOCKERS; CATECHOLAMINES; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, INTRAVENTRICULAR; MALE; POLYUNSATURATED ALKAMIDES; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2;

EID: 77953232962     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-010-0497-6     Document Type: Article

References (37)

1. U Baranowska M Göthert R Rudź B Malinowska 2008 Methanandamide allosterically inhibits in vivo the function of peripheral nicotinic acetylcholine receptors containing the α7-subunit J Pharmacol Exp Ther 326 912 917 10.1124/jpet.108.140863 18567834 1:CAS:528: DC%2BD1cXhtVGqurfL
2. S Bátkai P Pacher D Osei-Hyiaman S Radaeva J Liu J Harvey-White L Offertáler K Mackie MA Rudd RD Bukoski G Kunos 2004 Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension Circulation 110 1996 2002 10.1161/01.CIR.0000143230.23252.D2 15451779 1:CAS:528:DC%2BD2cXnvFams74%3D (Pubitemid 39331913)
3. F Bertolino JP Valentin JF Patoiseau JP Rieu FC Colpaert GW John 1997 Evidence for partial agonist properties of daltroban (BM 13, 505) at TP receptors in the anaesthetized open-chest rat Naunyn-Schmiedeberg's Arch Pharmacol 356 462 466 10.1007/PL00005077 1:CAS:528:DyaK2sXlvFOlsrw%3D (Pubitemid 27402085)
4. JJ Braszko J Własienko W Koziołkiewicz A Janecka K Wiśniewski 1991 The 3-7 fragment of angiotensin II is probably responsible for its psychoactive properties Brain Res 542 49 54 10.1016/0006-8993(91)90996-9 2054657 1:CAS:528:DyaK3MXks1Cqs7o%3D
5. 1 spinal receptors in urethane-anaesthetized rats Naunyn-Schmiedeberg's Arch Pharmacol 368 270 276 10.1007/s00210-003-0800-x 1:CAS:528:DC%2BD3sXot1OrsLc%3D (Pubitemid 37372549)
6. V Di Marzo 2009 The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation Pharmacol Res 60 77 84 10.1016/j.phrs.2009.02.010 19559360 1:CAS:528:DC%2BD1MXnvVWmsrY%3D
7. H Gao B Peng WJ Welch CS Wilcox 1997 Central thromboxane receptors: mRNA expression and mediation of pressor responses Am J Physiol 272 R1493 R1500 9176341 1:CAS:528:DyaK2sXjsFWgsbw%3D
8. SM Gardiner JE March PA Kemp T Bennet 2009 Factors influencing the regional haemodynamic responses to methanandamide and anandamide in conscious rats Br J Pharmacol 158 1143 1152 10.1111/j.1476-5381.2009.00363.x 19702785 1:CAS:528:DC%2BD1MXhsVSks7bF
9. AJ Hampson LM Bornheim M Scanziani CS Yost AT Gray BM Hansen DJ Leonoudakis PE Bickler 1998 Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission J Neurochem 70 671 676 9453561 1:CAS:528:DyaK1cXmtFartg%3D%3D
10. A Hedberg SE Hall ML Ogletree DN Harris EC Liu 1988 Characterization of [5, 6-3H]SQ 29, 548 as a high affinity radioligand, binding to thromboxane A2/prostaglandin H2-receptors in human platelets J Pharmacol Exp Ther 245 786 792 2968449 1:CAS:528:DyaL1cXlt1ejtLw%3D
11. JP Herman O Eyigor DR Ziegler L Jennes 2000 Expression of ionotropic glutamate receptor subunit mRNAs in the hypothalamic paraventricular nucleus of the rat J Comp Neurol 422 352 362 10.1002/1096-9861(20000703)422:3<352::AID- CNE3>3.0.CO;2-F 10861512 1:CAS:528:DC%2BD3cXksVCiurw%3D (Pubitemid 30387667)
12. G Kwolek A Zakrzeska E Schlicker M Göthert G Godlewski B Malinowska 2005 Central and peripheral components of the pressor effect of anandamide in urethane-anaesthetized rats Br J Pharmacol 145 567 575 10.1038/sj.bjp.0706195 15834445 1:CAS:528:DC%2BD2MXlslWhsLs%3D (Pubitemid 41032628)
13. KD Lake BR Martin G Kunos K Varga 1997 Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats Hypertension 29 1204 1210 9149688 1:CAS:528:DyaK2sXjs1Cks7c%3D
14. DP Li HL Pan 2007 Glutamatergic inputs in the hypothalamic paraventricular nucleus maintain sympathetic vasomotor tone in hypertension Hypertension 49 916 925 10.1161/01.HYP.0000259666.99449.74 17309953 1:CAS:528:DC%2BD2sXivVamtrc%3D (Pubitemid 351664213)
15. 3 receptors in the pithed rat Naunyn-Schmiedeberg's Arch Pharmacol 347 55 60 10.1007/BF00168772 1:CAS:528:DyaK3sXhsVSms78%3D
16. 1 receptor-mediated inhibition of the neurogenic vasopressor response in the pithed rat Naunyn-Schmiedeberg's Arch Pharmacol 356 197 202 10.1007/PL00005041 1:CAS:528:DyaK2sXkslGms7Y%3D (Pubitemid 27341974)
17. 1 receptor-mediated changes in heart rate and blood pressure in anaesthetized rats Naunyn-Schmiedeberg's Arch Pharmacol 364 562 569 10.1007/s00210-001-0498-6 1:CAS:528:DC%2BD3MXosFGnsLg%3D (Pubitemid 33145097)
18. 1 receptors Naunyn-Schmiedeberg's Arch Pharmacol 364 233 241 10.1007/s002100100450 1:CAS:528:DC%2BD3MXmtV2rs7g%3D (Pubitemid 32802152)
19. 2+ modulation of glycinergic synaptic currents in rodent hypoglossal motoneurones J Physiol 569 817 831 10.1113/jphysiol.2005.094862 16123105 1:CAS:528: DC%2BD28XivVKqsQ%3D%3D (Pubitemid 41830225)
20. Y Murakami S Okada M Nishihara K Yokotani 2002 Roles of brain prostaglandin E2 and thromboxane A2 in the activation of the central sympatho-adrenomedullary outflow in rats Eur J Pharmacol 452 289 294 10.1016/S0014-2999(02)02308-7 12359269 1:CAS:528:DC%2BD38XnsVagt70%3D (Pubitemid 35279431)
21. N Niederhoffer K Schmidt B Szabo 2003 The peripheral sympathetic nervous system is the major target of cannabinoids in eliciting cardiovascular depression Naunyn-Schmiedeberg's Arch Pharmacol 367 434 443 10.1007/s00210-003- 0755-y 1:CAS:528:DC%2BD3sXjslams7Y%3D (Pubitemid 36718294)
22. S Okada Y Murakami M Nishihara K Yokotani Y Osumi 2000 Perfusion of the hypothalamic paraventricular nucleus with N-methyl-d-aspartate produces thromboxane A2 and centrally activates adrenomedullary outflow in rats Neuroscience 96 585 590 10.1016/S0306-4522(99)00598-9 10717438 1:CAS:528:DC%2BD3cXhslamtr8%3D (Pubitemid 30136323)
23. 2-mediated mechanisms in rats Eur J Pharmacol 586 145 150 10.1016/j.ejphar.2008.02.069 18374330 1:CAS:528:DC%2BD1cXmsVGmtrs%3D
24. P Pacher S Bátkai G Kunos 2004 Haemodynamic profile and responsiveness to anandamide of TRPV1 receptor knock-out mice J Physiol 558 647 657 10.1113/jphysiol.2004.064824 15121805 1:CAS:528:DC%2BD2cXmtlKitbY%3D (Pubitemid 39117608)
25. P Pacher P Mukhopadhyay R Mohanraj G Godlewski S Bátkai G Kunos 2008 Modulation of the endocannabinoid system in cardiovascular disease: therapeutic potential and limitations Hypertension 52 601 607 10.1161/HYPERTENSIONAHA.105.063651 18779440 1:CAS:528:DC%2BD1cXhtV2jsrrL
26. T Pfitzer N Niederhoffer B Szabo 2005 Search for an endogenous cannabinoid-mediated effect in the sympathetic nervous system Naunyn-Schmiedeberg's Arch Pharmacol 371 9 17 10.1007/s00210-004-1003-9 1:CAS:528:DC%2BD2MXhsFGjsro%3D (Pubitemid 40379383)
27. 2-adrenergic receptors in rat brain Proc Natl Acad Sci USA 81 1585 1589 10.1073/pnas.81.5.1585 6324206 1:CAS:528:DyaL2cXhsFWmu7Y%3D
28. E Schlicker M Kathmann 2001 Modulation of transmitter release via presynaptic cannabinoid receptors Trends Pharmacol Sci 22 565 572 10.1016/S0165-6147(00)01805-8 11698100 1:CAS:528:DC%2BD3MXotFSmsbk%3D (Pubitemid 33042646)
29. MM Sellers JN Stallone 2008 Sympathy for the devil: the role of thromboxane in the regulation of vascular tone and blood pressure Am J Physiol Heart Circ Physiol 294 H1978 H1986 10.1152/ajpheart.01318.2007 18310512 1:CAS:528:DC%2BD1cXmtVWgtLc%3D
30. K Stegmeier J Pill B Müller-Beckmann FH Schmidt EC Witte HP Wolff H Patscheke 1984 The pharmacological profile of the thromboxane A2 antagonist BM 13.177. A new anti-platelet and anti-thrombotic drug Thromb Res 35 379 395 10.1016/0049-3848(84)90230-5 6385334 1:CAS:528:DyaL2cXls1ens78%3D
31. 1 cannabinoid receptor in the hypotensive action of anandamide Eur J Pharmacol 278 279 283 10.1016/0014-2999(95)00181-J 7589169 1:CAS:528:DyaK2MXlvFKns7Y%3D
32. K Varga KD Lake D Huangfu PG Guyenet G Kunos 1996 Mechanism of the hypotensive action of anandamide in anesthetized rats Hypertension 28 682 686 8843898 1:CAS:528:DyaK28XmsVOrtrY%3D
33. M Yalcin S Cavun MS Yilmaz V Savci 2005 The involvement of central cholinergic system in the pressor effect of intracerebroventricularly injected U-46619, a thromboxane A2 analog, in conscious normotensive rats Naunyn-Schmiedeberg's Arch Pharmacol 372 31 40 10.1007/s00210-005-1087-x 1:CAS:528:DC%2BD2MXhtVClt7rI (Pubitemid 41414043)
34. 1 receptor antagonist administration prevents endotoxic hypotension affecting norepinephrine release in the preoptic anterior hypothalamic area Shock 32 614 620 10.1097/SHK. 0b013e3181a4fd8f 19295473 1:CAS:528:DC%2BD1MXhsFOmsbnN
35. 1 receptors Eur J Pharmacol 423 203 210 10.1016/S0014-2999(01) 01112-8 11448486 1:CAS:528:DC%2BD3MXltVGjs7c%3D (Pubitemid 32614159)
36. M Yu D Ives CS Ramesha 1997 Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2 J Biol Chem 272 21181 21186 10.1074/jbc.272.34.21181 9261124 1:CAS:528:DyaK2sXls1Ojt7g%3D (Pubitemid 27373979)
37. Zakrzeska A, Schlicker E, Baranowska M, Kozłowska H, Kwolek K, Malinowska B (2010) Involvement of an O-1918-sensitive receptor in the anandamide-induced delayed hypotension in anaesthetized rats. Br J Pharmacol (online)